| Disease ID | Disease name | Source of annotation with NECTIN1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS119530 | OROFACIAL CLEFT | ClinVar, OMIM | link to OMIM | 6 | TP63, BMP4, IRF6, MSX1, NECTIN1, SUMO1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Cell adhesion molecules (CAMs) | hsa04514 | 5.36 |
| Adherens junction | hsa04520 | 6.26 |
| Herpes simplex infection | hsa05168 | 5.08 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Cell-Cell communication | R-HSA-1500931 | 5.87 |
| Nectin/Necl trans heterodimerization | R-HSA-420597 | 10.18 |
| Cell-cell junction organization | R-HSA-421270 | 7.03 |
| Cell junction organization | R-HSA-446728 | 6.51 |
| Adherens junctions interactions | R-HSA-418990 | 7.98 |
| GO term | GO ID | GO IC |
|---|---|---|
| cell adhesion molecule binding | GO:0050839 | 4.5 |
| signaling receptor activity | GO:0038023 | 2.49 |
| signal transducer activity | GO:0004871 | 2.28 |
| protein heterodimerization activity | GO:0046982 | 3.64 |
| virus receptor activity | GO:0001618 | 5.49 |
| carbohydrate binding | GO:0030246 | 4.17 |
| virion binding | GO:0046790 | 7.44 |
| molecular transducer activity | GO:0060089 | 2.32 |
| receptor activity | GO:0004872 | 2.32 |
| protein binding | GO:0005515 | 0.46 |
| protein dimerization activity | GO:0046983 | 2.72 |
| protein homodimerization activity | GO:0042803 | 3.16 |
| coreceptor activity | GO:0015026 | 6.1 |
| receptor binding | GO:0005102 | 2.43 |
| identical protein binding | GO:0042802 | 2.63 |
| binding | GO:0005488 | 0.18 |