Gene table of MSX1 : msh homeobox 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with MSX1	OMIM link	Number of associated genes	genes
PS305100	ECTODERMAL DYSPLASIA (SELECT EXAMPLES)	ClinVar, OMIM	link to OMIM	8	EDAR, GJB6, KRT74, KRT85, EDARADD, MSX1, EDA, HOXC13
PS106600	TOOTH AGENESIS, SELECTIVE	ClinVar, OMIM, HUMSAVAR	link to OMIM	5	PAX9, MSX1, EDA, LRP6, WNT10A
PS119530	OROFACIAL CLEFT	ClinVar, OMIM, HUMSAVAR	link to OMIM	6	TP63, BMP4, IRF6, MSX1, NECTIN1, SUMO1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
HTLV-I infection	hsa05166	4.59

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
nucleic acid binding transcription factor activity	GO:0001071	2.65
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
regulatory region nucleic acid binding	GO:0001067	3.03
transcription regulatory region DNA binding	GO:0044212	3.03
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001227	4.61
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
p53 binding	GO:0002039	5.53
binding	GO:0005488	0.18