| Disease ID | Disease name | Source of annotation with SUMO1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| PS119530 | OROFACIAL CLEFT | OMIM | link to OMIM | 6 | TP63, BMP4, IRF6, MSX1, NECTIN1, SUMO1 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| RNA transport | hsa03013 | 5.37 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Cytokine Signaling in Immune system | R-HSA-1280215 | 3.74 |
| SUMO is transferred from E1 to E2 (UBE2I, UBC9) | R-HSA-3065678 | 10.4 |
| SUMO is proteolytically processed | R-HSA-3065679 | 10.4 |
| G2/M Checkpoints | R-HSA-69481 | 6.46 |
| SUMO is conjugated to E1 (UBA2:SAE1) | R-HSA-3065676 | 10.66 |
| G2/M DNA damage checkpoint | R-HSA-69473 | 7.15 |
| Immune System | R-HSA-168256 | 2.37 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Cell Cycle Checkpoints | R-HSA-69620 | 5.64 |
| Cell Cycle | R-HSA-1640170 | 3.89 |
| Regulation of IFNG signaling | R-HSA-877312 | 9.18 |
| Interferon gamma signaling | R-HSA-877300 | 5.67 |
| SUMOylation | R-HSA-2990846 | 6.68 |
| SUMOylation of DNA damage response and repair proteins | R-HSA-3108214 | 6.77 |
| Interferon Signaling | R-HSA-913531 | 4.95 |
| Post-translational protein modification | R-HSA-597592 | 4.54 |
| Processing and activation of SUMO | R-HSA-3215018 | 9.81 |
| SUMO E3 ligases SUMOylate target proteins | R-HSA-3108232 | 6.77 |
| GO term | GO ID | GO IC |
|---|---|---|
| ubiquitin protein ligase binding | GO:0031625 | 4.17 |
| ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
| protein binding | GO:0005515 | 0.46 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| potassium channel regulator activity | GO:0015459 | 5.93 |
| poly(A) RNA binding | GO:0044822 | 2.69 |
| enzyme binding | GO:0019899 | 2.27 |
| transcription factor binding | GO:0008134 | 3.46 |
| molecular function regulator | GO:0098772 | 2.51 |
| binding | GO:0005488 | 0.18 |
| nucleic acid binding | GO:0003676 | 1.44 |
| channel regulator activity | GO:0016247 | 4.88 |
| ion channel binding | GO:0044325 | 5.02 |
| protein tag | GO:0031386 | 7.66 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| RNA binding | GO:0003723 | 2.36 |