Gene table of NPM1 : nucleophosmin

Gene-disease associations table

Disease ID	Disease name	Source of annotation with NPM1	OMIM link	Number of associated genes	genes
601626	LEUKEMIA, ACUTE MYELOID	ClinVar, OMIM	link to OMIM	23	FLT3, RUNX1, WHSC1L1, KIT, MLF1, CHIC2, CEBPA, LPP, SH3GL1, PICALM, NPM1, CBFB, ETV6, SETBP1, MLLT10, TERT, NUP214, JAK2, GATA2, TGM6, DDX41, NSD1, KRAS

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Nuclear import of Rev protein	R-HSA-180746	8.03
Host Interactions of HIV factors	R-HSA-162909	5.99
Deposition of new CENPA-containing nucleosomes at the centromere	R-HSA-606279	7.31
Interactions of Rev with host cellular proteins	R-HSA-177243	7.89
Infectious disease	R-HSA-5663205	4.47
HIV Infection	R-HSA-162906	5.22
Nucleosome assembly	R-HSA-774815	7.31
Cell Cycle	R-HSA-1640170	3.89
Chromosome Maintenance	R-HSA-73886	6.56
Disease	R-HSA-1643685	3.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
histone binding	GO:0042393	4.72
kinase regulator activity	GO:0019207	4.5
enzyme binding	GO:0019899	2.27
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
enzyme inhibitor activity	GO:0004857	3.78
molecular function regulator	GO:0098772	2.51
heterocyclic compound binding	GO:1901363	1.06
Tat protein binding	GO:0030957	7.66
transcription factor binding	GO:0008134	3.46
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
unfolded protein binding	GO:0051082	5.13
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
ribonucleoprotein complex binding	GO:0043021	5.15
ribosomal large subunit binding	GO:0043023	7.79
ribosomal small subunit binding	GO:0043024	7.25
identical protein binding	GO:0042802	2.63
protein homodimerization activity	GO:0042803	3.16
kinase inhibitor activity	GO:0019210	5.25
protein kinase regulator activity	GO:0019887	4.6
enzyme regulator activity	GO:0030234	2.85
poly(A) RNA binding	GO:0044822	2.69
NF-kappaB binding	GO:0051059	6.34
protein kinase inhibitor activity	GO:0004860	5.28
kinase binding	GO:0019900	3.32
protein kinase binding	GO:0019901	3.44
organic cyclic compound binding	GO:0097159	1.05
RNA binding	GO:0003723	2.36
protein binding	GO:0005515	0.46
protein dimerization activity	GO:0046983	2.72
protein heterodimerization activity	GO:0046982	3.64