Gene table of SDHC : succinate dehydrogenase complex subunit C

Gene-disease associations table

Disease IDDisease nameSource of annotation with SDHCOMIM linkNumber of associated genesgenes
606864PARAGANGLIOMA AND GASTRIC STROMAL SARCOMAOMIM link to OMIM 3SDHB, SDHD, SDHC
606764GASTROINTESTINAL STROMAL TUMORClinVar, OMIM link to OMIM 10SDHB, SLC19A1, MTHFR, SDHC, FOLR1, MTRR, KIT, PDGFRA, SHMT1, MTR
604287CARNEY TRIADClinVar link to OMIM 3SDHA, SDHB, SDHC
PS168000PARAGANGLIOMASClinVar, OMIM link to OMIM 5SDHC, SDHA, SDHD, SDHB, SDHAF2

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Annotation of the gene SDHC

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Parkinson's diseasehsa050125.59
Oxidative phosphorylationhsa001905.69
Metabolic pathwayshsa011002.49
Carbon metabolismhsa012006.03
Citrate cycle (TCA cycle)hsa000207.86
Huntington's diseasehsa050165.17
Alzheimer's diseasehsa050105.34
Non-alcoholic fatty liver disease (NAFLD)hsa049325.51
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Respiratory electron transportR-HSA-6111056.44
Pyruvate metabolism and Citric Acid (TCA) cycleR-HSA-714067.56
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.R-HSA-1632006.12
Citric acid cycle (TCA cycle)R-HSA-714038.73
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
oxidoreductase activityGO:00164913.12
cation bindingGO:00431691.4
metal ion bindingGO:00468721.41
heme bindingGO:00200374.86
tetrapyrrole bindingGO:00469064.8
organic cyclic compound bindingGO:00971591.05
oxidoreductase activity, acting on the CH-CH group of donorsGO:00166275.66
ion bindingGO:00431671.36
catalytic activityGO:00038241.05
bindingGO:00054880.18
succinate dehydrogenase activityGO:00001048.13
heterocyclic compound bindingGO:19013631.06
electron carrier activityGO:00090554.97