Disease ID | Disease name | Source of annotation with SDHC | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
606864 | PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA | OMIM | link to OMIM | 3 | SDHB, SDHD, SDHC |
606764 | GASTROINTESTINAL STROMAL TUMOR | ClinVar, OMIM | link to OMIM | 10 | SDHB, SLC19A1, MTHFR, SDHC, FOLR1, MTRR, KIT, PDGFRA, SHMT1, MTR |
604287 | CARNEY TRIAD | ClinVar | link to OMIM | 3 | SDHA, SDHB, SDHC |
PS168000 | PARAGANGLIOMAS | ClinVar, OMIM | link to OMIM | 5 | SDHC, SDHA, SDHD, SDHB, SDHAF2 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Parkinson's disease | hsa05012 | 5.59 |
Oxidative phosphorylation | hsa00190 | 5.69 |
Metabolic pathways | hsa01100 | 2.49 |
Carbon metabolism | hsa01200 | 6.03 |
Citrate cycle (TCA cycle) | hsa00020 | 7.86 |
Huntington's disease | hsa05016 | 5.17 |
Alzheimer's disease | hsa05010 | 5.34 |
Non-alcoholic fatty liver disease (NAFLD) | hsa04932 | 5.51 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Respiratory electron transport | R-HSA-611105 | 6.44 |
Pyruvate metabolism and Citric Acid (TCA) cycle | R-HSA-71406 | 7.56 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
Citric acid cycle (TCA cycle) | R-HSA-71403 | 8.73 |
The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
Metabolism | R-HSA-1430728 | 2.34 |
GO term | GO ID | GO IC |
---|---|---|
oxidoreductase activity | GO:0016491 | 3.12 |
cation binding | GO:0043169 | 1.4 |
metal ion binding | GO:0046872 | 1.41 |
heme binding | GO:0020037 | 4.86 |
tetrapyrrole binding | GO:0046906 | 4.8 |
organic cyclic compound binding | GO:0097159 | 1.05 |
oxidoreductase activity, acting on the CH-CH group of donors | GO:0016627 | 5.66 |
ion binding | GO:0043167 | 1.36 |
catalytic activity | GO:0003824 | 1.05 |
binding | GO:0005488 | 0.18 |
succinate dehydrogenase activity | GO:0000104 | 8.13 |
heterocyclic compound binding | GO:1901363 | 1.06 |
electron carrier activity | GO:0009055 | 4.97 |