Gene table of SDHD : succinate dehydrogenase complex subunit D

Gene-disease associations table

Disease IDDisease nameSource of annotation with SDHDOMIM linkNumber of associated genesgenes
114900CARCINOID TUMORS, INTESTINALOMIM link to OMIM 1SDHD
171300PHEOCHROMOCYTOMAOMIM, HUMSAVAR link to OMIM 8VHL, GDNF, SDHB, KIF1B, RET, MAX, TMEM127, SDHD
252011MITOCHONDRIAL COMPLEX II DEFICIENCYOMIM, HUMSAVAR link to OMIM 3SDHA, SDHAF1, SDHD
606864PARAGANGLIOMA AND GASTRIC STROMAL SARCOMAOMIM link to OMIM 3SDHB, SDHD, SDHC
PS168000PARAGANGLIOMASClinVar, OMIM, HUMSAVAR link to OMIM 5SDHC, SDHA, SDHD, SDHB, SDHAF2
PS158350COWDEN DISEASEClinVar, OMIM link to OMIM 7AKT1, PTEN, SEC23B, SDHB, PIK3CA, KLLN, SDHD

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Annotation of the gene SDHD

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Parkinson's diseasehsa050125.59
Oxidative phosphorylationhsa001905.69
Metabolic pathwayshsa011002.49
Carbon metabolismhsa012006.03
Citrate cycle (TCA cycle)hsa000207.86
Huntington's diseasehsa050165.17
Alzheimer's diseasehsa050105.34
Non-alcoholic fatty liver disease (NAFLD)hsa049325.51
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Respiratory electron transportR-HSA-6111056.44
Pyruvate metabolism and Citric Acid (TCA) cycleR-HSA-714067.56
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.R-HSA-1632006.12
Citric acid cycle (TCA cycle)R-HSA-714038.73
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
oxidoreductase activityGO:00164913.12
cation bindingGO:00431691.4
succinate dehydrogenase activityGO:00001048.13
heme bindingGO:00200374.86
tetrapyrrole bindingGO:00469064.8
metal ion bindingGO:00468721.41
organic cyclic compound bindingGO:00971591.05
oxidoreductase activity, acting on the CH-CH group of donorsGO:00166275.66
ion bindingGO:00431671.36
catalytic activityGO:00038241.05
cofactor bindingGO:00480374.16
bindingGO:00054880.18
ubiquinone bindingGO:00480398.35
quinone bindingGO:00480386.91
heterocyclic compound bindingGO:19013631.06
electron carrier activityGO:00090554.97