Gene table of SLC11A1 : solute carrier family 11 member 1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SLC11A1	OMIM link	Number of associated genes	genes
607948	MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO	OMIM	link to OMIM	11	IFNG, TIRAP, CD209, IFNGR1, MC3R, CISH, CCL2, IRGM, SLC11A1, TLR2, SP110
610446	BURULI ULCER, SUSCEPTIBILITY TO	ClinVar, OMIM	link to OMIM	1	SLC11A1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Mineral absorption	hsa04978	7.09
Lysosome	hsa04142	5.78

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Infectious disease	R-HSA-5663205	4.47
Phagosomal maturation (early endosomal stage)	R-HSA-1222556	7.89
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	R-HSA-425366	6.34
Transmembrane transport of small molecules	R-HSA-382551	3.79
Latent infection of Homo sapiens with Mycobacterium tuberculosis	R-HSA-1222352	7.89
SLC-mediated transmembrane transport	R-HSA-425407	4.95
Metal ion SLC transporters	R-HSA-425410	8.34
Disease	R-HSA-1643685	3.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ion antiporter activity	GO:0099516	5.75
binding	GO:0005488	0.18
cation:cation antiporter activity	GO:0015491	6.48
transition metal ion transmembrane transporter activity	GO:0046915	6.05
transmembrane transporter activity	GO:0022857	2.82
transporter activity	GO:0005215	2.57
metal ion transmembrane transporter activity	GO:0046873	3.71
active transmembrane transporter activity	GO:0022804	3.85
protein homodimerization activity	GO:0042803	3.16
antiporter activity	GO:0015297	5.33
secondary active transmembrane transporter activity	GO:0015291	4.29
protein binding	GO:0005515	0.46
metal ion:proton antiporter activity	GO:0051139	9.74
cation transmembrane transporter activity	GO:0008324	3.32
solute:proton antiporter activity	GO:0015299	6.74
solute:cation antiporter activity	GO:0015298	6.24
substrate-specific transmembrane transporter activity	GO:0022891	2.9
inorganic cation transmembrane transporter activity	GO:0022890	3.49
substrate-specific transporter activity	GO:0022892	2.72
ion transmembrane transporter activity	GO:0015075	3.04
monovalent inorganic cation transmembrane transporter activity	GO:0015077	3.87
identical protein binding	GO:0042802	2.63
manganese ion transmembrane transporter activity	GO:0005384	7.95
protein dimerization activity	GO:0046983	2.72
hydrogen ion transmembrane transporter activity	GO:0015078	5.01