Gene table of IRGM : immunity related GTPase M

Gene-disease associations table

Disease ID	Disease name	Source of annotation with IRGM	OMIM link	Number of associated genes	genes
607948	MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO	OMIM	link to OMIM	11	IFNG, TIRAP, CD209, IFNGR1, MC3R, CISH, CCL2, IRGM, SLC11A1, TLR2, SP110
PS266600	INFLAMMATORY BOWEL DISEASE	ClinVar, OMIM	link to OMIM	10	ATG16L1, IL10RB, IRGM, IL10RA, NOD2, IRF5, IL23R, ABCB1, SLC22A5, IL6

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Toxoplasmosis	hsa05145	5.71

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
guanyl ribonucleotide binding	GO:0032561	3.73
hydrolase activity	GO:0016787	1.9
guanyl nucleotide binding	GO:0019001	3.73
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
catalytic activity	GO:0003824	1.05
nucleoside phosphate binding	GO:1901265	1.96
purine ribonucleoside triphosphate binding	GO:0035639	2.22
heterocyclic compound binding	GO:1901363	1.06
small molecule binding	GO:0036094	1.89
ribonucleotide binding	GO:0032553	2.19
nucleoside binding	GO:0001882	2.21
binding	GO:0005488	0.18
ribonucleoside binding	GO:0032549	2.22
purine ribonucleotide binding	GO:0032555	2.2
purine nucleotide binding	GO:0017076	2.19
nucleotide binding	GO:0000166	1.96
purine ribonucleoside binding	GO:0032550	2.22
purine nucleoside binding	GO:0001883	2.22
GTP binding	GO:0005525	3.78