Disease table of PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO OMIM ID: 607507

Gene-disease associations table

GeneAssociated with PSORIATIC ARTHRITIS, SUSCEPTIBILITY TO inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
LTAOMIMHGNC link6p21.333608446, 610988, 607507
NOD2OMIMHGNC link16q12.14PS266600, 607507, 186580, 609464

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
LTAYES1MSC0
NOD2YES2NR1I2, NFKB10
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
TNF signaling pathwayhsa046685.962NOD2, LTA

NET-GE enrichment

Term New enriched termICP valueGenes
TNF signaling pathway (hsa04668) -5.960.005NOD2, LTA
REACTOME pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Cytokine Signaling in Immune systemR-HSA-12802153.742NOD2, LTA
Immune SystemR-HSA-1682562.372NOD2, LTA
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.182NOD2, LTA
protein binding (GO:0005515) 0.462NOD2, LTA
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
regulation of cell proliferation (GO:0042127) 2.412NOD2, LTA
positive regulation of response to external stimulus (GO:0032103) 4.172NOD2, LTA
regulation of response to external stimulus (GO:0032101) 3.062NOD2, LTA
positive regulation of response to stimulus (GO:0048584) 2.182NOD2, LTA
regulation of response to stimulus (GO:0048583) 1.542NOD2, LTA
regulation of inflammatory response (GO:0050727) 4.032NOD2, LTA
positive regulation of defense response (GO:0031349) 3.832NOD2, LTA
biological regulation (GO:0065007) 0.392NOD2, LTA
signal transduction (GO:0007165) 1.282NOD2, LTA
regulation of cell death (GO:0010941) 2.432NOD2, LTA
regulation of apoptotic process (GO:0042981) 2.52NOD2, LTA
regulation of biological process (GO:0050789) 0.452NOD2, LTA
regulation of defense response (GO:0031347) 3.112NOD2, LTA
positive regulation of inflammatory response (GO:0050729) 4.982NOD2, LTA
response to external biotic stimulus (GO:0043207) 3.132NOD2, LTA
positive regulation of multicellular organismal process (GO:0051240) 2.492NOD2, LTA
response to bacterium (GO:0009617) 4.182NOD2, LTA
positive regulation of immune system process (GO:0002684) 2.962NOD2, LTA
regulation of programmed cell death (GO:0043067) 2.492NOD2, LTA
regulation of immune system process (GO:0002682) 2.52NOD2, LTA
single-organism process (GO:0044699) 0.482NOD2, LTA
positive regulation of biological process (GO:0048518) 1.22NOD2, LTA
negative regulation of biological process (GO:0048519) 1.332NOD2, LTA
positive regulation of cell proliferation (GO:0008284) 3.012NOD2, LTA
cellular process (GO:0009987) 0.262NOD2, LTA
regulation of cellular process (GO:0050794) 0.52NOD2, LTA
defense response (GO:0006952) 2.782NOD2, LTA
response to stress (GO:0006950) 1.82NOD2, LTA
single-organism cellular process (GO:0044763) 0.652NOD2, LTA
regulation of multicellular organismal process (GO:0051239) 1.872NOD2, LTA
immune response (GO:0006955) 2.862NOD2, LTA
response to chemical (GO:0042221) 1.982NOD2, LTA
response to other organism (GO:0051707) 3.482NOD2, LTA
response to organic substance (GO:0010033) 2.22NOD2, LTA
multi-organism process (GO:0051704) 2.652NOD2, LTA
response to oxygen-containing compound (GO:1901700) 2.572NOD2, LTA
regulation of immune response (GO:0050776) 2.982NOD2, LTA
response to biotic stimulus (GO:0009607) 3.092NOD2, LTA
response to external stimulus (GO:0009605) 2.552NOD2, LTA
response to stimulus (GO:0050896) 1.222NOD2, LTA
defense response to bacterium (GO:0042742) 4.312NOD2, LTA
positive regulation of immune response (GO:0050778) 3.42NOD2, LTA
immune system process (GO:0002376) 2.292NOD2, LTA
regulation of cytokine production (GO:0001817) 3.42NOD2, LTA
response to molecule of bacterial origin (GO:0002237) 3.992NOD2, LTA
defense response to other organism (GO:0098542) 3.752NOD2, LTA
positive regulation of cytokine production (GO:0001819) 3.822NOD2, LTA
regulation of response to stress (GO:0080134) 2.532NOD2, LTA
negative regulation of cellular process (GO:0048523) 1.412NOD2, LTA
positive regulation of cellular process (GO:0048522) 1.32NOD2, LTA

NET-GE enrichment

Term New enriched termICP valueGenes
neutrophil migration (GO:1990266) NEW5.520.024NOD2, LTA
regulation of interferon-gamma production (GO:0032649) NEW5.210.01NOD2, LTA
regulation of adaptive immune response (GO:0002819) NEW4.910.041NOD2, LTA
regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) NEW7.430.001NOD2, LTA
positive regulation of humoral immune response (GO:0002922) NEW7.090.001NOD2, LTA
positive regulation of leukocyte mediated immunity (GO:0002705) NEW5.320.019NOD2, LTA
regulation of humoral immune response (GO:0002920) NEW5.820.003NOD2, LTA
regulation of leukocyte mediated immunity (GO:0002703) NEW4.70.045NOD2, LTA
defense response to bacterium (GO:0042742) -4.310.044NOD2, LTA
positive regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002925) NEW8.340.0NOD2, LTA
positive regulation of immunoglobulin mediated immune response (GO:0002891) NEW6.470.0NOD2, LTA
positive regulation of lymphocyte mediated immunity (GO:0002708) NEW5.490.018NOD2, LTA
negative regulation of growth of symbiont in host (GO:0044130) NEW7.020.002NOD2, LTA
granulocyte migration (GO:0097530) NEW5.410.038NOD2, LTA
response to nutrient (GO:0007584) NEW4.490.038NOD2, LTA
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) NEW5.480.018NOD2, LTA
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) NEW4.990.037NOD2, LTA
positive regulation of adaptive immune response (GO:0002821) NEW5.420.019NOD2, LTA
regulation of immunoglobulin mediated immune response (GO:0002889) NEW6.040.028NOD2, LTA
defense response to Gram-positive bacterium (GO:0050830) NEW5.540.004NOD2, LTA
negative regulation of multi-organism process (GO:0043901) NEW4.70.017NOD2, LTA
positive regulation of B cell mediated immunity (GO:0002714) NEW6.470.0NOD2, LTA
regulation of growth of symbiont in host (GO:0044126) NEW6.960.0NOD2, LTA
negative regulation of growth of symbiont involved in interaction with host (GO:0044146) NEW6.960.0NOD2, LTA
modulation of growth of symbiont involved in interaction with host (GO:0044144) NEW6.90.002NOD2, LTA
regulation of lymphocyte mediated immunity (GO:0002706) NEW4.990.033NOD2, LTA
regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903) NEW3.820.043NOD2, LTA
regulation of B cell mediated immunity (GO:0002712) NEW6.020.029NOD2, LTA
regulation of inflammatory response to antigenic stimulus (GO:0002861) NEW6.730.001NOD2, LTA
positive regulation of immune effector process (GO:0002699) NEW4.690.045NOD2, LTA
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
membrane (GO:0016020) 0.682NOD2, LTA
cell part (GO:0044464) 0.112NOD2, LTA
plasma membrane (GO:0005886) 1.392NOD2, LTA