Gene table of ADRB3 : adrenoceptor beta 3

Gene-disease associations table

Disease IDDisease nameSource of annotation with ADRB3OMIM linkNumber of associated genesgenes
601665OBESITYOMIM link to OMIM 15PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL

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Annotation of the gene ADRB3

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
cGMP-PKG signaling pathwayhsa040225.32
Salivary secretionhsa049706.23
Calcium signaling pathwayhsa040205.22
Neuroactive ligand-receptor interactionhsa040804.58
Endocytosishsa041444.92
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Amine ligand-binding receptorsR-HSA-3752807.59
Signaling by GPCRR-HSA-3727902.68
GPCR downstream signalingR-HSA-3883963.07
Class A/1 (Rhodopsin-like receptors)R-HSA-3730764.69
GPCR ligand bindingR-HSA-5007924.19
G alpha (s) signalling eventsR-HSA-4185555.99
AdrenoceptorsR-HSA-3906969.81
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
GO:00513808.35
GO:00316999.05
molecular transducer activityGO:00600892.32
bindingGO:00054880.18
signal transducer activityGO:00048712.28
G-protein coupled receptor bindingGO:00016644.18
G-protein coupled receptor activityGO:00049302.95
adrenergic receptor activityGO:00049356.97
GO:00049398.64
G-protein coupled amine receptor activityGO:00082275.83
adrenergic receptor bindingGO:00316906.85
identical protein bindingGO:00428022.63
protein homodimerization activityGO:00428033.16
receptor bindingGO:00051022.43
GO:00513797.95
catecholamine bindingGO:19013386.97
GO:00150529.74
transmembrane signaling receptor activityGO:00048882.57
protein bindingGO:00055150.46
organic cyclic compound bindingGO:00971591.05
protein dimerization activityGO:00469832.72
transmembrane receptor activityGO:00996002.53
receptor activityGO:00048722.32