Disease ID | Disease name | Source of annotation with ADRB3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
601665 | OBESITY | OMIM | link to OMIM | 15 | PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
cGMP-PKG signaling pathway | hsa04022 | 5.32 |
Salivary secretion | hsa04970 | 6.23 |
Calcium signaling pathway | hsa04020 | 5.22 |
Neuroactive ligand-receptor interaction | hsa04080 | 4.58 |
Endocytosis | hsa04144 | 4.92 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Amine ligand-binding receptors | R-HSA-375280 | 7.59 |
Signaling by GPCR | R-HSA-372790 | 2.68 |
GPCR downstream signaling | R-HSA-388396 | 3.07 |
Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
GPCR ligand binding | R-HSA-500792 | 4.19 |
G alpha (s) signalling events | R-HSA-418555 | 5.99 |
Adrenoceptors | R-HSA-390696 | 9.81 |
Signal Transduction | R-HSA-162582 | 1.78 |
GO term | GO ID | GO IC |
---|---|---|
signaling receptor activity | GO:0038023 | 2.49 |
GO:0051380 | 8.35 | |
GO:0031699 | 9.05 | |
molecular transducer activity | GO:0060089 | 2.32 |
binding | GO:0005488 | 0.18 |
signal transducer activity | GO:0004871 | 2.28 |
G-protein coupled receptor binding | GO:0001664 | 4.18 |
G-protein coupled receptor activity | GO:0004930 | 2.95 |
adrenergic receptor activity | GO:0004935 | 6.97 |
GO:0004939 | 8.64 | |
G-protein coupled amine receptor activity | GO:0008227 | 5.83 |
adrenergic receptor binding | GO:0031690 | 6.85 |
identical protein binding | GO:0042802 | 2.63 |
protein homodimerization activity | GO:0042803 | 3.16 |
receptor binding | GO:0005102 | 2.43 |
GO:0051379 | 7.95 | |
catecholamine binding | GO:1901338 | 6.97 |
GO:0015052 | 9.74 | |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
protein binding | GO:0005515 | 0.46 |
organic cyclic compound binding | GO:0097159 | 1.05 |
protein dimerization activity | GO:0046983 | 2.72 |
transmembrane receptor activity | GO:0099600 | 2.53 |
receptor activity | GO:0004872 | 2.32 |