Gene table of UCP1 : uncoupling protein 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with UCP1OMIM linkNumber of associated genesgenes
601665OBESITYOMIM link to OMIM 15PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL

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Annotation of the gene UCP1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Huntington's diseasehsa050165.17
PPAR signaling pathwayhsa033206.56
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.R-HSA-1632006.12
The citric acid (TCA) cycle and respiratory electron transportR-HSA-14285175.71
The fatty acid cycling modelR-HSA-16782610.66
The proton buffering modelR-HSA-16782710.66
Mitochondrial Uncoupling ProteinsR-HSA-16618710.66
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
oxidative phosphorylation uncoupler activityGO:00170779.05
transporter activityGO:00052152.57
transmembrane transporter activityGO:00228572.82
structural constituent of ribosomeGO:00037354.32
structural molecule activityGO:00051983.1