Disease ID | Disease name | Source of annotation with UCP3 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
601665 | OBESITY | OMIM, HUMSAVAR | link to OMIM | 15 | PPARGC1B, AGRP, PPARG, MC4R, ADRB3, CARTPT, UCP3, SIM1, POMC, ENPP1, ADRB2, SDC3, NR0B2, UCP1, GHRL |
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REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | R-HSA-163200 | 6.12 |
The citric acid (TCA) cycle and respiratory electron transport | R-HSA-1428517 | 5.71 |
The fatty acid cycling model | R-HSA-167826 | 10.66 |
The proton buffering model | R-HSA-167827 | 10.66 |
Mitochondrial Uncoupling Proteins | R-HSA-166187 | 10.66 |
Metabolism | R-HSA-1430728 | 2.34 |
GO term | GO ID | GO IC |
---|---|---|
transporter activity | GO:0005215 | 2.57 |
structural molecule activity | GO:0005198 | 3.1 |
structural constituent of ribosome | GO:0003735 | 4.32 |
transmembrane transporter activity | GO:0022857 | 2.82 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
oxidative phosphorylation uncoupler activity | GO:0017077 | 9.05 |