Disease ID | Disease name | Source of annotation with CUL4B | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS309510 | MENTAL RETARDATION, X-LINKED SYNDROMIC | ClinVar, OMIM, HUMSAVAR | link to OMIM | 27 | AP1S2, PRPS1, IGBP1, RBMX, HUWE1, RAB40AL, HSD17B10, ATP6AP2, PHF8, CLIC2, CASK, TAF1, FGD1, CUL4B, PQBP1, ZDHHC9, NONO, UPF3B, SMS, HDAC8, UBE2A, MECP2, KDM5C, ARX, SLC9A6, GRIA3, PHF6 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Ubiquitin mediated proteolysis | hsa04120 | 5.63 |
Nucleotide excision repair | hsa03420 | 7.15 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
DNA Repair | R-HSA-73894 | 5.8 |
Recognition of DNA damage by PCNA-containing replication complex | R-HSA-110314 | 8.18 |
DNA Damage Bypass | R-HSA-73893 | 7.46 |
GO term | GO ID | GO IC |
---|---|---|
ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
ubiquitin protein ligase binding | GO:0031625 | 4.17 |
ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
protein binding | GO:0005515 | 0.46 |
ubiquitin protein ligase activity | GO:0061630 | 4.47 |
enzyme binding | GO:0019899 | 2.27 |
heterocyclic compound binding | GO:1901363 | 1.06 |
catalytic activity | GO:0003824 | 1.05 |
transferase activity | GO:0016740 | 1.95 |
binding | GO:0005488 | 0.18 |
nucleic acid binding | GO:0003676 | 1.44 |
DNA binding | GO:0003677 | 1.92 |
organic cyclic compound binding | GO:0097159 | 1.05 |
ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
damaged DNA binding | GO:0003684 | 5.58 |
ubiquitin-like protein ligase activity | GO:0061659 | 4.44 |