Gene table of FGD1 : FYVE, RhoGEF and PH domain containing 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with FGD1OMIM linkNumber of associated genesgenes
PS309510MENTAL RETARDATION, X-LINKED SYNDROMICClinVar, OMIM, HUMSAVAR link to OMIM 27AP1S2, PRPS1, IGBP1, RBMX, HUWE1, RAB40AL, HSD17B10, ATP6AP2, PHF8, CLIC2, CASK, TAF1, FGD1, CUL4B, PQBP1, ZDHHC9, NONO, UPF3B, SMS, HDAC8, UBE2A, MECP2, KDM5C, ARX, SLC9A6, GRIA3, PHF6

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Annotation of the gene FGD1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Regulation of actin cytoskeletonhsa048104.9
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
p75 NTR receptor-mediated signallingR-HSA-1937046.59
Signalling by NGFR-HSA-1665204.23
G alpha (12/13) signalling eventsR-HSA-4164826.75
GPCR downstream signalingR-HSA-3883963.07
Signaling by Rho GTPasesR-HSA-1943154.43
Rho GTPase cycleR-HSA-1948406.04
Cell death signalling via NRAGE, NRIF and NADER-HSA-2049987.05
Signaling by GPCRR-HSA-3727902.68
Signal TransductionR-HSA-1625821.78
NRAGE signals death through JNKR-HSA-1936487.49
Associated GO terms for Molecular function
GO termGO IDGO IC
Rho guanyl-nucleotide exchange factor activityGO:00050895.37
Ras guanyl-nucleotide exchange factor activityGO:00050884.31
metal ion bindingGO:00468721.41
cation bindingGO:00431691.4
guanyl-nucleotide exchange factor activityGO:00050854.02
enzyme bindingGO:00198992.27
ion bindingGO:00431671.36
small GTPase bindingGO:00312674.13
GTPase bindingGO:00510204.05
bindingGO:00054880.18
protein bindingGO:00055150.46
molecular function regulatorGO:00987722.51