Gene table of HSD17B10 : hydroxysteroid 17-beta dehydrogenase 10

Gene-disease associations table

Disease IDDisease nameSource of annotation with HSD17B10OMIM linkNumber of associated genesgenes
30043817-BETA-HYDROXYSTEROID DEHYDROGENASE X DEFICIENCYClinVar, OMIM, HUMSAVAR link to OMIM 1HSD17B10
PS309510MENTAL RETARDATION, X-LINKED SYNDROMICClinVar, OMIM link to OMIM 27AP1S2, PRPS1, IGBP1, RBMX, HUWE1, RAB40AL, HSD17B10, ATP6AP2, PHF8, CLIC2, CASK, TAF1, FGD1, CUL4B, PQBP1, ZDHHC9, NONO, UPF3B, SMS, HDAC8, UBE2A, MECP2, KDM5C, ARX, SLC9A6, GRIA3, PHF6

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Annotation of the gene HSD17B10

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Valine, leucine and isoleucine degradationhsa002807.09
Alzheimer's diseasehsa050105.34
Metabolic pathwayshsa011002.49
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of amino acids and derivativesR-HSA-712915.4
MetabolismR-HSA-14307282.34
Branched-chain amino acid catabolismR-HSA-708958.89
Associated GO terms for Molecular function
GO termGO IDGO IC
NAD bindingGO:00512875.77
bindingGO:00054880.18
nucleic acid bindingGO:00036761.44
cholate 7-alpha-dehydrogenase activityGO:00087099.74
3-hydroxyacyl-CoA dehydrogenase activityGO:00038577.54
testosterone dehydrogenase [NAD(P)] activityGO:00302839.74
heterocyclic compound bindingGO:19013631.06
nucleoside phosphate bindingGO:19012651.96
oxidoreductase activityGO:00164913.12
coenzyme bindingGO:00506624.53
beta-amyloid bindingGO:00015406.21
nucleotide bindingGO:00001661.96
estradiol 17-beta-dehydrogenase activityGO:00043037.34
identical protein bindingGO:00428022.63
steroid dehydrogenase activityGO:00162296.34
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00337646.48
steroid hormone receptor bindingGO:00352585.32
estrogen receptor bindingGO:00303316.05
amide bindingGO:00332184.14
poly(A) RNA bindingGO:00448222.69
nuclear hormone receptor bindingGO:00352574.7
3-hydroxy-2-methylbutyryl-CoA dehydrogenase activityGO:00470159.74
lipid bindingGO:00082893.26
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
cofactor bindingGO:00480374.16
steroid bindingGO:00054965.24
hormone receptor bindingGO:00514274.57
oxidoreductase activity, acting on CH-OH group of donorsGO:00166144.83
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorGO:00166165.0
peptide bindingGO:00422774.22
organic cyclic compound bindingGO:00971591.05
acetoacetyl-CoA reductase activityGO:00184549.74
RNA bindingGO:00037232.36
protein bindingGO:00055150.46
receptor bindingGO:00051022.43