| Disease ID | Disease name | Source of annotation with CXCR1 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 609423 | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, SUSCEPTIBILITY TO | OMIM | link to OMIM | 16 | HLA-C, IFNG, CCL3, CD209, IL4R, KIR3DL1, CCL2, TLR3, CCR2, CX3CR1, CCL11, CCR5, CXCL12, CCL3L1, CXCR1, IL10 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Epithelial cell signaling in Helicobacter pylori infection | hsa05120 | 6.58 |
| Chemokine signaling pathway | hsa04062 | 5.19 |
| Endocytosis | hsa04144 | 4.92 |
| Cytokine-cytokine receptor interaction | hsa04060 | 4.67 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Signaling by GPCR | R-HSA-372790 | 2.68 |
| G alpha (i) signalling events | R-HSA-418594 | 5.1 |
| Class A/1 (Rhodopsin-like receptors) | R-HSA-373076 | 4.69 |
| Peptide ligand-binding receptors | R-HSA-375276 | 5.41 |
| Chemokine receptors bind chemokines | R-HSA-380108 | 7.2 |
| GPCR downstream signaling | R-HSA-388396 | 3.07 |
| GPCR ligand binding | R-HSA-500792 | 4.19 |
| Signal Transduction | R-HSA-162582 | 1.78 |
| GO term | GO ID | GO IC |
|---|---|---|
| G-protein coupled peptide receptor activity | GO:0008528 | 4.86 |
| G-protein coupled receptor activity | GO:0004930 | 2.95 |
| signal transducer activity | GO:0004871 | 2.28 |
| G-protein coupled chemoattractant receptor activity | GO:0001637 | 6.52 |
| C-X-C chemokine binding | GO:0019958 | 7.79 |
| interleukin-8 binding | GO:0019959 | 8.64 |
| chemokine binding | GO:0019956 | 6.69 |
| cytokine binding | GO:0019955 | 5.21 |
| interleukin-8 receptor activity | GO:0004918 | 9.05 |
| chemokine receptor activity | GO:0004950 | 6.52 |
| molecular transducer activity | GO:0060089 | 2.32 |
| transmembrane signaling receptor activity | GO:0004888 | 2.57 |
| peptide receptor activity | GO:0001653 | 4.84 |
| receptor activity | GO:0004872 | 2.32 |
| protein binding | GO:0005515 | 0.46 |
| signaling receptor activity | GO:0038023 | 2.49 |
| C-X-C chemokine receptor activity | GO:0016494 | 7.79 |
| cytokine receptor activity | GO:0004896 | 5.24 |
| transmembrane receptor activity | GO:0099600 | 2.53 |
| binding | GO:0005488 | 0.18 |