| Disease ID | Disease name | Source of annotation with F7 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 227500 | FACTOR VII DEFICIENCY | OMIM, HUMSAVAR | link to OMIM | 1 | F7 |
| 608446 | MYOCARDIAL INFARCTION, SUSCEPTIBILITY TO | OMIM | link to OMIM | 14 | LTA, ACE, ITGB3, OLR1, GCLC, ESR1, GCLM, LGALS2, MIAT, LRP8, F7, PSMA6, F13A1, TNFSF4 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Complement and coagulation cascades | hsa04610 | 6.58 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Gamma-carboxylation of protein precursors | R-HSA-159740 | 9.81 |
| Circadian Clock | R-HSA-400253 | 7.03 |
| Gamma carboxylation, hypusine formation and arylsulfatase activation | R-HSA-163841 | 7.81 |
| Metabolism of proteins | R-HSA-392499 | 3.41 |
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | R-HSA-159763 | 9.98 |
| Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | R-HSA-159854 | 9.52 |
| Extrinsic Pathway of Fibrin Clot Formation | R-HSA-140834 | 10.66 |
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | R-HSA-159782 | 9.81 |
| Post-translational protein modification | R-HSA-597592 | 4.54 |
| Formation of Fibrin Clot (Clotting Cascade) | R-HSA-140877 | 7.7 |
| BMAL1:CLOCK,NPAS2 activates circadian gene expression | R-HSA-1368108 | 7.59 |
| Hemostasis | R-HSA-109582 | 3.98 |
| GO term | GO ID | GO IC |
|---|---|---|
| glycoprotein binding | GO:0001948 | 5.11 |
| hydrolase activity | GO:0016787 | 1.9 |
| endopeptidase activity | GO:0004175 | 3.63 |
| serine-type endopeptidase activity | GO:0004252 | 4.4 |
| serine hydrolase activity | GO:0017171 | 4.26 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| cation binding | GO:0043169 | 1.4 |
| ion binding | GO:0043167 | 1.36 |
| serine-type peptidase activity | GO:0008236 | 4.27 |
| catalytic activity | GO:0003824 | 1.05 |
| peptidase activity, acting on L-amino acid peptides | GO:0070011 | 3.26 |
| binding | GO:0005488 | 0.18 |
| protein binding | GO:0005515 | 0.46 |
| peptidase activity | GO:0008233 | 3.23 |
| metal ion binding | GO:0046872 | 1.41 |
| receptor binding | GO:0005102 | 2.43 |
| calcium ion binding | GO:0005509 | 3.17 |