Gene table of GCLM : glutamate-cysteine ligase modifier subunit

Gene-disease associations table

Disease IDDisease nameSource of annotation with GCLMOMIM linkNumber of associated genesgenes
608446MYOCARDIAL INFARCTION, SUSCEPTIBILITY TOOMIM link to OMIM 14LTA, ACE, ITGB3, OLR1, GCLC, ESR1, GCLM, LGALS2, MIAT, LRP8, F7, PSMA6, F13A1, TNFSF4

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Annotation of the gene GCLM

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Metabolic pathwayshsa011002.49
Glutathione metabolismhsa004806.96
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Biological oxidationsR-HSA-2118595.55
Metabolism of amino acids and derivativesR-HSA-712915.4
Sulfur amino acid metabolismR-HSA-16146358.46
Glutathione conjugationR-HSA-1565907.98
Phase II conjugationR-HSA-1565806.52
Glutathione synthesis and recyclingR-HSA-1744039.52
MetabolismR-HSA-14307282.34
Associated GO terms for Molecular function
GO termGO IDGO IC
protein heterodimerization activityGO:00469823.64
catalytic activityGO:00038241.05
glutamate-cysteine ligase catalytic subunit bindingGO:00352269.74
glutamate-cysteine ligase activityGO:00043579.05
enzyme regulator activityGO:00302342.85
enzyme bindingGO:00198992.27
acid-amino acid ligase activityGO:00168816.69
ligase activity, forming carbon-nitrogen bondsGO:00168795.7
bindingGO:00054880.18
protein bindingGO:00055150.46
protein dimerization activityGO:00469832.72
molecular function regulatorGO:00987722.51
ligase activityGO:00168743.72