Gene table of IGF2R : insulin like growth factor 2 receptor

Gene-disease associations table

Disease ID	Disease name	Source of annotation with IGF2R	OMIM link	Number of associated genes	genes
114550	HEPATOCELLULAR CARCINOMA	ClinVar, OMIM	link to OMIM	11	CDKN3, CASP8, MTUS1, TP53, MET, AXIN1, APC, IGF2R, PIK3CA, PDGFRL, CTNNB1

Download the gene annotation in CSV format

Annotation of the gene IGF2R

Associated genes in ENSEMBL

ENSG00000197081

Associated proteins - SwissProt Accession ID

P11717

Associated PDB IDs

Cytogenetic Band

6q25.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

USF2

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Lysosome	hsa04142	5.78

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Membrane Trafficking	R-HSA-199991	5.26
trans-Golgi Network Vesicle Budding	R-HSA-199992	6.85
Golgi Associated Vesicle Biogenesis	R-HSA-432722	7.23
Clathrin derived vesicle budding	R-HSA-421837	6.85
Vesicle-mediated transport	R-HSA-5653656	4.33

Associated GO terms for Molecular function

GO term	GO ID	GO IC
signaling receptor activity	GO:0038023	2.49
phosphoprotein binding	GO:0051219	5.64
carbohydrate binding	GO:0030246	4.17
enzyme binding	GO:0019899	2.27
growth factor binding	GO:0019838	4.89
molecular transducer activity	GO:0060089	2.32
receptor activity	GO:0004872	2.32
signal transducer activity	GO:0004871	2.28
anion binding	GO:0043168	4.17
G-protein coupled receptor activity	GO:0004930	2.95
insulin-like growth factor-activated receptor activity	GO:0005010	8.64
ion binding	GO:0043167	1.36
transmembrane receptor protein tyrosine kinase activity	GO:0004714	5.55
G-protein alpha-subunit binding	GO:0001965	6.6
protein tyrosine kinase activity	GO:0004713	4.54
protein kinase activity	GO:0004672	3.27
insulin-like growth factor binding	GO:0005520	6.37
retinoid binding	GO:0005501	6.1
identical protein binding	GO:0042802	2.63
glycoprotein binding	GO:0001948	5.11
carboxylic acid binding	GO:0031406	4.64
transporter activity	GO:0005215	2.57
kinase activity	GO:0016301	2.93
lipid binding	GO:0008289	3.26
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
monocarboxylic acid binding	GO:0033293	5.61
insulin-like growth factor II binding	GO:0031995	7.66
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
isoprenoid binding	GO:0019840	6.05
carbohydrate derivative binding	GO:0097367	2.03
transmembrane signaling receptor activity	GO:0004888	2.57
transferase activity	GO:0016740	1.95
monosaccharide binding	GO:0048029	5.85
mannose binding	GO:0005537	6.85
protein binding	GO:0005515	0.46
retinoic acid binding	GO:0001972	6.6
transmembrane receptor protein kinase activity	GO:0019199	5.32
transmembrane receptor activity	GO:0099600	2.53
binding	GO:0005488	0.18