Gene table of KIF4A : kinesin family member 4A

Gene-disease associations table

Disease ID	Disease name	Source of annotation with KIF4A	OMIM link	Number of associated genes	genes
PS309530	MENTAL RETARDATION, NONSYNDROMIC, X-LINKED	OMIM	link to OMIM	25	THOC2, HCFC1, RPS6KA3, USP9X, MID2, RAB39B, KIAA2022, ZNF81, PAK3, IQSEC2, DLG3, TSPAN7, ZDHHC15, ZNF711, KIF4A, ACSL4, BRWD3, IL1RAPL1, GDI1, SYP, ARHGEF6, ARX, DDX3X, GRIA3, FTSJ1

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
L1CAM interactions	R-HSA-373760	6.19
Immune System	R-HSA-168256	2.37
Recycling pathway of L1	R-HSA-437239	7.62
Hemostasis	R-HSA-109582	3.98
MHC class II antigen presentation	R-HSA-2132295	6.01
Axon guidance	R-HSA-422475	3.93
Factors involved in megakaryocyte development and platelet production	R-HSA-983231	5.88
Kinesins	R-HSA-983189	7.7
Adaptive Immune System	R-HSA-1280218	3.19
Developmental Biology	R-HSA-1266738	3.48

Associated GO terms for Molecular function

GO term	GO ID	GO IC
ATPase activity	GO:0016887	3.65
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
nucleotide binding	GO:0000166	1.96
ATP-dependent microtubule motor activity, plus-end-directed	GO:0008574	6.91
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
ATP-dependent microtubule motor activity	GO:1990939	6.85
motor activity	GO:0003774	4.81
microtubule motor activity	GO:0003777	5.34
hydrolase activity	GO:0016787	1.9
tubulin binding	GO:0015631	4.1
microtubule binding	GO:0008017	4.42
nucleoside-triphosphatase activity	GO:0017111	3.09
nucleoside phosphate binding	GO:1901265	1.96
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
cytoskeletal protein binding	GO:0008092	3.02
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
pyrophosphatase activity	GO:0016462	3.04
adenyl ribonucleotide binding	GO:0032559	2.41
ATP binding	GO:0005524	2.43
protein binding	GO:0005515	0.46
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19