Disease table of MENTAL RETARDATION, NONSYNDROMIC, X-LINKED OMIM ID: PS309530

Gene-disease associations table

GeneAssociated with MENTAL RETARDATION, NONSYNDROMIC, X-LINKED inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
ZDHHC15OMIMHGNC linkXq13.31PS309530
IL1RAPL1ClinVar, OMIMHGNC linkXp21.31PS309530
RAB39BClinVar, OMIMHGNC linkXq282PS309530, 311510
GRIA3ClinVar, OMIM, HUMSAVARHGNC linkXq252PS309510, PS309530
KIAA2022ClinVar, OMIMHGNC linkXq13.31PS309530
USP9XClinVar, OMIM, HUMSAVARHGNC linkXp11.41PS309530
IQSEC2ClinVar, OMIM, HUMSAVARHGNC linkXp11.221PS309530
MID2ClinVar, OMIM, HUMSAVARHGNC linkXq22.31PS309530
DLG3ClinVar, OMIMHGNC linkXq13.11PS309530
HCFC1ClinVar, OMIM, HUMSAVARHGNC linkXq281PS309530
ARHGEF6ClinVar, OMIMHGNC linkXq26.31PS309530
KIF4AOMIMHGNC linkXq13.11PS309530
FTSJ1ClinVar, OMIMHGNC linkXp11.231PS309530
BRWD3ClinVar, OMIM, HUMSAVARHGNC linkXq21.11PS309530
DDX3XClinVar, OMIM, HUMSAVARHGNC linkXp11.41PS309530
ZNF81ClinVar, OMIM, HUMSAVARHGNC linkXp11.231PS309530
TSPAN7ClinVar, OMIM, HUMSAVARHGNC linkXp11.41PS309530
THOC2ClinVar, OMIM, HUMSAVARHGNC linkXq251PS309530
GDI1ClinVar, OMIM, HUMSAVARHGNC linkXq281PS309530
RPS6KA3ClinVar, OMIM, HUMSAVARHGNC linkXp22.122303600, PS309530
ARXClinVar, OMIM, HUMSAVARHGNC linkXp21.35PS607432, PS309510, 300004, PS308350, PS309530
ZNF711ClinVar, OMIMHGNC linkXq21.11PS309530
ACSL4ClinVar, OMIM, HUMSAVARHGNC linkXq231PS309530
SYPClinVar, OMIM, HUMSAVARHGNC linkXp11.231PS309530
PAK3ClinVar, OMIM, HUMSAVARHGNC linkXq231PS309530

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By sub-band
Shared sub_bandNumber of genes associated with the diseaseGenes associated with the disease
Xp11.233ZNF81, FTSJ1, SYP
Xq232ACSL4, PAK3
Xq21.12ZNF711, BRWD3
Xp21.32IL1RAPL1, ARX
Xp11.43USP9X, DDX3X, TSPAN7
Xq283RAB39B, GDI1, HCFC1
Xq252THOC2, GRIA3
Xq13.12KIF4A, DLG3
Xq13.32ZDHHC15, KIAA2022
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
Xq212ZNF711, BRWD3
Xq283RAB39B, GDI1, HCFC1
Xq134ZDHHC15, KIAA2022, DLG3, KIF4A
Xq252THOC2, GRIA3
Xp212IL1RAPL1, ARX
Xq232ACSL4, PAK3
Xp117USP9X, DDX3X, IQSEC2, SYP, FTSJ1, ZNF81, TSPAN7
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
Xq14ZDHHC15, KIAA2022, DLG3, KIF4A
Xq211RAB39B, MID2, THOC2, ZNF711, BRWD3, ARHGEF6, GDI1, PAK3, HCFC1, GRIA3, ACSL4
Xp17USP9X, DDX3X, IQSEC2, SYP, FTSJ1, ZNF81, TSPAN7
Xp23IL1RAPL1, RPS6KA3, ARX
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
Xp10USP9X, RPS6KA3, DDX3X, ARX, IQSEC2, SYP, ZNF81, FTSJ1, IL1RAPL1, TSPAN7
Xq15RAB39B, MID2, KIF4A, THOC2, KIAA2022, ARHGEF6, BRWD3, DLG3, PAK3, ZDHHC15, ZNF711, HCFC1, GRIA3, ACSL4, GDI1
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
X25RAB39B, RPS6KA3, THOC2, ZNF711, DLG3, GDI1, GRIA3, ARX, USP9X, PAK3, BRWD3, ARHGEF6, ZNF81, MID2, KIF4A, KIAA2022, IQSEC2, ZDHHC15, IL1RAPL1, SYP, HCFC1, ACSL4, TSPAN7, DDX3X, FTSJ1
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
HCFC1YES4RB1, E2F4, BAP1, E2F10
ARXYES1KDM5C0
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
HCFC1YES2YY1, E2F40
RPS6KA3YES1NR3C10
SYPYES2SP1, PKNOX10
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
IL1RAPL1USP9XNo1CFTR
RAB39BMID2No1GOLGA2
GRIA3MID2No1SDCBP
GRIA3DLG3No1DLG4
KIAA2022USP9XNo2TERF2, TERF1
KIAA2022BRWD3No1TERF1
KIAA2022DDX3XNo1TERF2
KIAA2022THOC2No1TERF1
USP9XIQSEC2No1XPO1
USP9XMID2No5UBE2D1, IGBP1, UBXN1, UBE2D2, DCX
USP9XHCFC1No5NTRK1, HDAC5, CUL3, SIRT7, EGFR
USP9XKIF4ANo2NTRK1, SIRT7
USP9XFTSJ1No1CUL3
USP9XBRWD3No2UBXN7, TERF1
USP9XDDX3XNo15CCDC8, UBL7, PRPF8, CRY2, MCM2, ERG, TERF2, CAND1, RPS6KB2, ATP6V1F, XPO1, NTRK1, SMAD3, HDAC5, CUL3
USP9XTHOC2No5NTRK1, KIAA0368, TERF1, SIRT7, SMAD4
USP9XGDI1No4UNK, NTRK1, UCHL3, SIRT7
USP9XRPS6KA3No2NTRK1, EGFR
USP9XZNF711No1CUL3
USP9XACSL4No1HECW2
USP9XPAK3No1SNCA
IQSEC2DLG3No1ELAVL1
IQSEC2HCFC1No1ELAVL1
IQSEC2DDX3XNo2ELAVL1, XPO1
IQSEC2ACSL4No1ELAVL1
MID2HCFC1No1THAP7
MID2KIF4ANo1NXF1
MID2DDX3XNo1BYSL
MID2THOC2No1TOP3B
DLG3HCFC1No2PPP1CA, ELAVL1
DLG3FTSJ1No1ZFP91
DLG3DDX3XNo2CUL2, ELAVL1
DLG3THOC2No1CRIPT
DLG3RPS6KA3No1GDA
DLG3ACSL4No1ELAVL1
HCFC1KIF4ANo3EED, NTRK1, SIRT7
HCFC1FTSJ1No1CUL3
HCFC1DDX3XNo14SP1, LMNA, CDK2, EED, YY1, CUL3, RPA1, PPP1CB, ELAVL1, RPA2, NTRK1, RPA3, HDAC5, FBXW11
HCFC1TSPAN7No1CREB3
HCFC1THOC2No6EED, RPA1, SIRT7, RPA2, NTRK1, RPA3
HCFC1GDI1No4NTRK1, TRIM28, CDK2, SIRT7
HCFC1RPS6KA3No4NTRK1, HSPA8, EGFR, HSP90AA1
HCFC1ZNF711No2CUL3, PHF8
HCFC1ACSL4No1ELAVL1
ARHGEF6DDX3XNo2ARRB2, RAC1
ARHGEF6TSPAN7No1NEF
ARHGEF6THOC2No1MED4
ARHGEF6GDI1No1CDC42
ARHGEF6PAK3No3ARHGEF7, RAC1, CDC42
KIF4AFTSJ1No2SIRT6, APP
KIF4ADDX3XNo2EED, NTRK1
KIF4ATHOC2No3EED, NTRK1, SIRT7
KIF4AGDI1No2NTRK1, SIRT7
KIF4ARPS6KA3No2NTRK1, NFATC1
KIF4AACSL4No1APP
FTSJ1DDX3XNo1CUL3
FTSJ1RPS6KA3No1CDC37
FTSJ1ZNF711No1CUL3
FTSJ1ACSL4No1APP
BRWD3DDX3XNo2CSNK2A1, CUL4B
BRWD3THOC2No1TERF1
DDX3XTHOC2No15STAU1, OBSL1, RNF2, CUL7, ALYREF, VCAM1, EIF4A3, RPA1, EED, SRSF1, SUZ12, RPA2, NTRK1, RPA3, LGR4
DDX3XGDI1No5NTRK1, DCUN1D1, CUL5, CDK2, NEDD8
DDX3XRPS6KA3No4NTRK1, EIF3C, ESR1, NEDD4
DDX3XZNF711No1CUL3
DDX3XACSL4No4PARK2, YWHAQ, ELAVL1, TP53
DDX3XPAK3No1RAC1
THOC2GDI1No2NTRK1, SIRT7
THOC2RPS6KA3No1NTRK1
GDI1RPS6KA3No1NTRK1
GDI1ACSL4No1MINOS1
GDI1PAK3No1CDC42
RPS6KA3ZNF711No1HIST1H3A

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
GRIA3DLG3No-10GRIA2, GRIN2A, GRIN3A, GRIA4, GRIA1, CACNG2, GRIN3B, GRIN1, DLG4, GRIN2B
USP9XDLG3No-1UBC
USP9XKIF4ANo-2UBC, BIRC5
USP9XDDX3XNo-1UBC
USP9XTHOC2No-2UBC, SMAD4
USP9XRPS6KA3No-3UBC, RPTOR, MTOR
USP9XACSL4No-1UBC
USP9XPAK3No-1UBC
DLG3KIF4ANo-1UBC
DLG3DDX3XNo-1UBC
DLG3THOC2No-1UBC
DLG3RPS6KA3No-3UBC, PHLPP2, PHLPP1
DLG3ACSL4No-1UBC
DLG3PAK3No-1UBC
ARHGEF6RPS6KA3No-1HRAS
ARHGEF6PAK3Yesbinding33RAC1, ACTA1, LAMA5, PXN, PAK2, CDC42, PTK2, RHOV, LAMB3, PAK6, ITGB1, CHRNA1, LAMB1, LAMA3, RRAS, LAMA2, PAK7, PAK1, CHRM1, LAMC3, UTRN, LAMB2, PAK4, SRC, DAG1, GIT2, CTTN, ARHGEF7, RAPSN, LAMC2, ITGA1, LAMC1, RAC3
KIF4ADDX3XNo-1UBC
KIF4ATHOC2No-1UBC
KIF4ARPS6KA3No-8AP2S1, AP2A2, SH3GL2, CLTA, AP2M1, UBC, AP2B1, AP2A1
KIF4AACSL4No-1UBC
KIF4APAK3No-1UBC
DDX3XTHOC2No-3NCBP1, UBC, ALYREF
DDX3XRPS6KA3No-2UBC, RPS6
DDX3XACSL4No-1UBC
DDX3XPAK3No-1UBC
THOC2RPS6KA3No-1UBC
THOC2ACSL4No-1UBC
THOC2PAK3No-1UBC
RPS6KA3ARXNo-2MEF2C, MEF2A
RPS6KA3ACSL4No-1UBC
RPS6KA3PAK3No-2UBC, MAPK14
ACSL4PAK3No-1UBC

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Gene1Gene2Direct InteractionComplexesNumber of shared interactorsShared genes in interaction
HCFC1KIF4ANo-2HDAC1, SIN3A
HCFC1DDX3XNo-1PRPF31
HCFC1THOC2No-1PRPF31
DDX3XTHOC2YesSpliceosome141SF1, DDX5, CDC40, CDC5L, EIF4A3, SNRPD2, SNRPD1, SNRNP200, LSM2, SF3B6, SYF2, DDX23, PAXBP1, SLU7, RNPS1, SNRPE, ZNF207, DHX9, AQR, SNRNP27, CACTIN, SNRNP70, SNRPD3, CTNNBL1, CFAP20, SNRPB, DHX15, XAB2, SRSF11, SF3A1, RBM15, IGF2BP3, CIRBP, SF3A3, THOC5, SRSF4, CWC15, PRPF8, WTAP, PRPF4, SF3B2, MFAP1, HTATSF1, SF3B1, PPIL2, MAGOH, ISY1, TRA2B, SNRPA, NCBP2, WBP11, LSM6, PPWD1, SNRPC, PPIL3, PPIH, SNRPG, CDK12, SART1, SF3A2, ALYREF, BUD13, SNU13, THOC3, CWC22, TCERG1, NCBP1, DHX8, BUD31, PRPF31, SRRT, PABPC1, U2AF1, DHX16, DHX38, CRNKL1, RBM8A, CPSF6, LSM3, TFIP11, SMNDC1, SRSF6, LUC7L3, PPM1G, RBM22, PPIE, THOC6, SRSF5, DDX39B, DDX41, NUDT21, PRPF40A, TXNL4A, CD2BP2, MOV10, PRPF6, SNRPB2, THOC7, U2AF2, SKIV2L2, PRPF4B, DDX46, RBM39, PUF60, FNBP3, BCAS2, SNRPF, SRSF2, SRRM1, SMU1, DNAJC8, SRRM2, SNW1, U2SURP, KIAA1429, USP39, SRSF7, IK, SNRPA1, SRSF1, SNRNP40, ACIN1, C19ORF43, SRSF9, PLRG1, PRPF3, THOC1, SPEN, SF3B4, LSM7, PPIL1, DGCR14, SF3B3, LSM4, PRPF19, DDX17, RBM25, SRSF3, EFTUD2, RBM17, PRPF18

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CENSUS
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
USP9XDDX3XNo1ATP6V1F

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Regulation of actin cytoskeletonhsa048104.92PAK3, ARHGEF6
Transcriptional misregulation in cancerhsa052025.212GRIA3, TSPAN7
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Signal TransductionR-HSA-1625821.785USP9X, RPS6KA3, GDI1, ARHGEF6, PAK3
Axon guidanceR-HSA-4224753.934DLG3, RPS6KA3, PAK3, KIF4A
Developmental BiologyR-HSA-12667383.484DLG3, RPS6KA3, PAK3, KIF4A
L1CAM interactionsR-HSA-3737606.193DLG3, RPS6KA3, KIF4A
Immune SystemR-HSA-1682562.373RPS6KA3, PAK3, KIF4A
Signaling by Rho GTPasesR-HSA-1943154.433PAK3, GDI1, ARHGEF6
Neuronal SystemR-HSA-1123164.823GRIA3, DLG3, RPS6KA3
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic CellR-HSA-1123145.853GRIA3, DLG3, RPS6KA3
Transmission across Chemical SynapsesR-HSA-1123155.283GRIA3, DLG3, RPS6KA3
Signaling by GPCRR-HSA-3727902.682RPS6KA3, ARHGEF6
Signalling by NGFR-HSA-1665204.232RPS6KA3, ARHGEF6
Generic Transcription PathwayR-HSA-2124363.862USP9X, ZNF711
Gene ExpressionR-HSA-741602.722USP9X, ZNF711
Innate Immune SystemR-HSA-1682493.172RPS6KA3, PAK3
Recycling pathway of L1R-HSA-4372397.622RPS6KA3, KIF4A
Rho GTPase cycleR-HSA-1948406.042GDI1, ARHGEF6
Activation of NMDA receptor upon glutamate binding and postsynaptic eventsR-HSA-4427557.72GRIA3, RPS6KA3
Adaptive Immune SystemR-HSA-12802183.192PAK3, KIF4A

NET-GE enrichment

Term New enriched termICP valueGenes
L1CAM interactions (R-HSA-373760) -6.190.041USP9X, RPS6KA3, DLG3, KIF4A
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.1819THOC2, ARHGEF6, GDI1, PAK3, RAB39B, IL1RAPL1, ACSL4, DLG3, RPS6KA3, DDX3X, HCFC1, USP9X, SYP, KIF4A, ARX, ZDHHC15, ZNF81, ZNF711, MID2
protein binding (GO:0005515) 0.4615THOC2, IL1RAPL1, GDI1, RAB39B, ARHGEF6, PAK3, DLG3, RPS6KA3, HCFC1, USP9X, SYP, KIF4A, MID2, DDX3X, ZNF711
catalytic activity (GO:0003824) 1.0512GDI1, PAK3, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, KIF4A, ZDHHC15, DLG3, ACSL4, MID2
organic cyclic compound binding (GO:0097159) 1.0511THOC2, RAB39B, PAK3, DDX3X, RPS6KA3, SYP, KIF4A, ARX, ZNF81, ACSL4, ZNF711
heterocyclic compound binding (GO:1901363) 1.0610THOC2, RAB39B, PAK3, DDX3X, RPS6KA3, KIF4A, ARX, ZNF81, ACSL4, ZNF711
small molecule binding (GO:0036094) 1.897RAB39B, DDX3X, RPS6KA3, SYP, PAK3, ACSL4, KIF4A
cation binding (GO:0043169) 1.46RPS6KA3, MID2, ZNF711, ZDHHC15, ZNF81, PAK3
ion binding (GO:0043167) 1.366RPS6KA3, MID2, ZNF711, ZDHHC15, ZNF81, PAK3
carbohydrate derivative binding (GO:0097367) 2.036RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
purine nucleoside binding (GO:0001883) 2.226RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
nucleotide binding (GO:0000166) 1.966RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
purine ribonucleoside triphosphate binding (GO:0035639) 2.226RAB39B, DDX3X, RPS6KA3, KIF4A, ACSL4, PAK3
transferase activity (GO:0016740) 1.956RPS6KA3, DLG3, FTSJ1, HCFC1, ZDHHC15, PAK3
ribonucleotide binding (GO:0032553) 2.196RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
nucleic acid binding (GO:0003676) 1.446THOC2, DDX3X, KIF4A, ARX, ZNF81, ZNF711
ribonucleoside binding (GO:0032549) 2.226RAB39B, DDX3X, RPS6KA3, KIF4A, ACSL4, PAK3
purine ribonucleotide binding (GO:0032555) 2.26RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
purine nucleotide binding (GO:0017076) 2.196RAB39B, DDX3X, RPS6KA3, KIF4A, ACSL4, PAK3
metal ion binding (GO:0046872) 1.416RPS6KA3, MID2, ZNF711, ZDHHC15, ZNF81, PAK3
purine ribonucleoside binding (GO:0032550) 2.226RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
nucleoside phosphate binding (GO:1901265) 1.966RAB39B, DDX3X, RPS6KA3, PAK3, ACSL4, KIF4A
nucleoside binding (GO:0001882) 2.216RAB39B, DDX3X, RPS6KA3, KIF4A, ACSL4, PAK3
adenyl nucleotide binding (GO:0030554) 2.45DDX3X, RPS6KA3, ACSL4, KIF4A, PAK3
adenyl ribonucleotide binding (GO:0032559) 2.415DDX3X, RPS6KA3, ACSL4, KIF4A, PAK3
ATP binding (GO:0005524) 2.435DDX3X, RPS6KA3, ACSL4, KIF4A, PAK3
DNA binding (GO:0003677) 1.925ZNF711, ZNF81, KIF4A, DDX3X, ARX
transcription factor activity, sequence-specific DNA binding (GO:0003700) 2.654HCFC1, ZNF81, ZNF711, ARX
transporter activity (GO:0005215) 2.574GRIA3, DLG3, SYP, IL1RAPL1
molecular function regulator (GO:0098772) 2.514IQSEC2, RPS6KA3, GDI1, ARHGEF6
nucleic acid binding transcription factor activity (GO:0001071) 2.654HCFC1, ZNF81, ZNF711, ARX
enzyme binding (GO:0019899) 2.274DLG3, RPS6KA3, GDI1, PAK3
substrate-specific transmembrane transporter activity (GO:0022891) 2.93GRIA3, DLG3, IL1RAPL1
hydrolase activity (GO:0016787) 1.93USP9X, DDX3X, KIF4A
substrate-specific transporter activity (GO:0022892) 2.723GRIA3, DLG3, IL1RAPL1
cytoskeletal protein binding (GO:0008092) 3.023KIF4A, RAB39B, MID2
transferase activity, transferring phosphorus-containing groups (GO:0016772) 2.773DLG3, RPS6KA3, PAK3
ion channel activity (GO:0005216) 3.713GRIA3, DLG3, IL1RAPL1
kinase activity (GO:0016301) 2.933DLG3, RPS6KA3, PAK3
ion transmembrane transporter activity (GO:0015075) 3.043GRIA3, DLG3, IL1RAPL1
transmembrane transporter activity (GO:0022857) 2.823GRIA3, DLG3, IL1RAPL1
channel activity (GO:0015267) 3.63GRIA3, DLG3, IL1RAPL1
macromolecular complex binding (GO:0044877) 2.613DDX3X, HCFC1, ARX
protein domain specific binding (GO:0019904) 3.323DLG3, SYP, PAK3
passive transmembrane transporter activity (GO:0022803) 3.63GRIA3, DLG3, IL1RAPL1
substrate-specific channel activity (GO:0022838) 3.673GRIA3, DLG3, IL1RAPL1
enzyme regulator activity (GO:0030234) 2.853RPS6KA3, GDI1, ARHGEF6
identical protein binding (GO:0042802) 2.633SYP, HCFC1, MID2
gated channel activity (GO:0022836) 3.963GRIA3, DLG3, IL1RAPL1
signal transducer activity (GO:0004871) 2.282GRIA3, PAK3
guanyl-nucleotide exchange factor activity (GO:0005085) 4.022IQSEC2, ARHGEF6
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding (GO:0003705) 5.232HCFC1, ARX
molecular transducer activity (GO:0060089) 2.322GRIA3, DLG3
GTPase binding (GO:0051020) 4.052PAK3, GDI1
kinase binding (GO:0019900) 3.322DLG3, RPS6KA3
zinc ion binding (GO:0008270) 2.662ZDHHC15, MID2
ATPase activity (GO:0016887) 3.652DDX3X, KIF4A
enzyme activator activity (GO:0008047) 3.562GDI1, ARHGEF6
sequence-specific DNA binding (GO:0043565) 2.792ZNF711, ARX
sequence-specific double-stranded DNA binding (GO:1990837) 3.22ZNF711, ARX
transition metal ion binding (GO:0046914) 2.482ZDHHC15, MID2
ligase activity (GO:0016874) 3.722ACSL4, MID2
ligand-gated ion channel activity (GO:0015276) 4.82GRIA3, DLG3
protein serine/threonine kinase activity (GO:0004674) 3.642RPS6KA3, PAK3
transferase activity, transferring acyl groups (GO:0016746) 4.22ZDHHC15, HCFC1
transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747) 4.372ZDHHC15, HCFC1
protein kinase activity (GO:0004672) 3.272RPS6KA3, PAK3
double-stranded DNA binding (GO:0003690) 3.092ZNF711, ARX
RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981) 3.292HCFC1, ARX
RNA binding (GO:0003723) 2.362THOC2, DDX3X
tubulin binding (GO:0015631) 4.12KIF4A, MID2
RNA polymerase II regulatory region DNA binding (GO:0001012) 3.362ZNF711, ARX
microtubule binding (GO:0008017) 4.422KIF4A, MID2
regulatory region DNA binding (GO:0000975) 3.032ZNF711, ARX
GTPase activator activity (GO:0005096) 4.112GDI1, ARHGEF6
nucleoside-triphosphatase activity (GO:0017111) 3.092DDX3X, KIF4A
Ras GTPase binding (GO:0017016) 4.22PAK3, GDI1
GTPase regulator activity (GO:0030695) 4.012GDI1, ARHGEF6
nucleoside-triphosphatase regulator activity (GO:0060589) 3.922GDI1, ARHGEF6
transcription regulatory region DNA binding (GO:0044212) 3.032ZNF711, ARX
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818) 3.032DDX3X, KIF4A
small GTPase binding (GO:0031267) 4.132PAK3, GDI1
phosphotransferase activity, alcohol group as acceptor (GO:0016773) 3.082RPS6KA3, PAK3
hydrolase activity, acting on acid anhydrides (GO:0016817) 3.032DDX3X, KIF4A
regulatory region nucleic acid binding (GO:0001067) 3.032ZNF711, ARX
pyrophosphatase activity (GO:0016462) 3.042DDX3X, KIF4A
transcription regulatory region sequence-specific DNA binding (GO:0000976) 3.242ZNF711, ARX
RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) 3.372ZNF711, ARX
ligand-gated channel activity (GO:0022834) 4.82GRIA3, DLG3
receptor binding (GO:0005102) 2.432DLG3, IL1RAPL1
chromatin binding (GO:0003682) 3.642HCFC1, ARX
transmembrane receptor activity (GO:0099600) 2.532GRIA3, DLG3
receptor activity (GO:0004872) 2.322GRIA3, DLG3
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.2623IL1RAPL1, RPS6KA3, ARX, ZNF81, ACSL4, THOC2, ARHGEF6, DLG3, SYP, KIF4A, TSPAN7, RAB39B, GRIA3, FTSJ1, MID2, IQSEC2, PAK3, DDX3X, HCFC1, USP9X, BRWD3, ZDHHC15, ZNF711
biological regulation (GO:0065007) 0.3920ARHGEF6, TSPAN7, DDX3X, GDI1, IL1RAPL1, RAB39B, PAK3, GRIA3, DLG3, RPS6KA3, USP9X, HCFC1, IQSEC2, SYP, MID2, ARX, BRWD3, ZNF81, ACSL4, ZNF711
regulation of biological process (GO:0050789) 0.4520PAK3, TSPAN7, GDI1, RAB39B, ARHGEF6, ACSL4, GRIA3, IL1RAPL1, DLG3, RPS6KA3, IQSEC2, HCFC1, USP9X, SYP, MID2, ARX, BRWD3, ZNF81, DDX3X, ZNF711
regulation of cellular process (GO:0050794) 0.520ARHGEF6, TSPAN7, GDI1, IL1RAPL1, RAB39B, PAK3, GRIA3, DLG3, ZNF81, RPS6KA3, IQSEC2, HCFC1, USP9X, SYP, MID2, ARX, BRWD3, ACSL4, DDX3X, ZNF711
single-organism process (GO:0044699) 0.4819THOC2, ARHGEF6, GDI1, DDX3X, IL1RAPL1, RAB39B, PAK3, GRIA3, DLG3, RPS6KA3, USP9X, HCFC1, IQSEC2, SYP, ARX, KIAA2022, ZDHHC15, ACSL4, KIF4A
single-organism cellular process (GO:0044763) 0.6517THOC2, ARHGEF6, IL1RAPL1, RAB39B, PAK3, GRIA3, DDX3X, RPS6KA3, IQSEC2, HCFC1, USP9X, SYP, KIF4A, ARX, ZDHHC15, DLG3, ACSL4
metabolic process (GO:0008152) 0.5816THOC2, PAK3, ZNF81, GDI1, ARHGEF6, ACSL4, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, DLG3, ZNF711
organic substance metabolic process (GO:0071704) 0.6315THOC2, PAK3, ZNF81, ARHGEF6, ACSL4, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, DLG3, ZNF711
cellular metabolic process (GO:0044237) 0.6915THOC2, PAK3, ZNF81, ARHGEF6, ACSL4, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, DLG3, ZNF711
primary metabolic process (GO:0044238) 0.6915THOC2, PAK3, ZNF81, ARHGEF6, ACSL4, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, DLG3, ZNF711
macromolecule metabolic process (GO:0043170) 0.8313THOC2, ARHGEF6, PAK3, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, ZNF81, ZNF711
cellular component organization or biogenesis (GO:0071840) 1.2213IL1RAPL1, RAB39B, ARHGEF6, DDX3X, IQSEC2, HCFC1, USP9X, SYP, PAK3, BRWD3, ZDHHC15, DLG3, KIF4A
cellular macromolecule metabolic process (GO:0044260) 0.9313THOC2, ARHGEF6, PAK3, FTSJ1, DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX, ZDHHC15, ZNF81, ZNF711
cellular component organization (GO:0016043) 1.2413IL1RAPL1, RAB39B, ARHGEF6, DDX3X, IQSEC2, HCFC1, USP9X, SYP, PAK3, BRWD3, ZDHHC15, DLG3, KIF4A
localization (GO:0051179) 1.412THOC2, GDI1, IL1RAPL1, RAB39B, GRIA3, DDX3X, MID2, SYP, KIF4A, ZDHHC15, DLG3, ACSL4
regulation of cellular metabolic process (GO:0031323) 1.0711PAK3, DLG3, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, DDX3X, ZNF711
regulation of metabolic process (GO:0019222) 1.0211PAK3, DLG3, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, DDX3X, ZNF711
developmental process (GO:0032502) 1.3610THOC2, ARX, DLG3, RPS6KA3, USP9X, SYP, KIAA2022, ZDHHC15, ACSL4, PAK3
regulation of primary metabolic process (GO:0080090) 1.0810PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.4310PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.4610PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
response to stimulus (GO:0050896) 1.2210GDI1, ARHGEF6, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, MID2, ACSL4, PAK3
regulation of biosynthetic process (GO:0009889) 1.3710PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of macromolecule metabolic process (GO:0060255) 1.0810PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of macromolecule biosynthetic process (GO:0010556) 1.4310PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
signal transduction (GO:0007165) 1.2810TSPAN7, GDI1, RAB39B, ARHGEF6, GRIA3, DDX3X, RPS6KA3, IL1RAPL1, USP9X, PAK3
regulation of cellular biosynthetic process (GO:0031326) 1.3810PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
positive regulation of biological process (GO:0048518) 1.210ARHGEF6, IL1RAPL1, PAK3, DDX3X, RPS6KA3, HCFC1, MID2, ARX, ACSL4, ZNF711
negative regulation of biological process (GO:0048519) 1.3310GDI1, IL1RAPL1, DLG3, RPS6KA3, HCFC1, USP9X, MID2, ARX, ACSL4, DDX3X
establishment of localization (GO:0051234) 1.4810THOC2, GDI1, IL1RAPL1, RAB39B, GRIA3, DLG3, SYP, ZDHHC15, ACSL4, KIF4A
regulation of nitrogen compound metabolic process (GO:0051171) 1.3610PAK3, DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of RNA metabolic process (GO:0051252) 1.529DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
transport (GO:0006810) 1.519THOC2, GDI1, IL1RAPL1, RAB39B, GRIA3, DLG3, SYP, ACSL4, KIF4A
regulation of nucleic acid-templated transcription (GO:1903506) 1.559DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
single-organism developmental process (GO:0044767) 1.499THOC2, ARX, DLG3, USP9X, SYP, KIAA2022, ZDHHC15, ACSL4, PAK3
regulation of transcription, DNA-templated (GO:0006355) 1.569DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of RNA biosynthetic process (GO:2001141) 1.559DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
regulation of gene expression (GO:0010468) 1.379DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, MID2, ARX, ZNF81, ZNF711
negative regulation of cellular process (GO:0048523) 1.419GDI1, IL1RAPL1, DLG3, RPS6KA3, HCFC1, USP9X, MID2, ARX, DDX3X
positive regulation of cellular process (GO:0048522) 1.39IL1RAPL1, ARHGEF6, PAK3, DDX3X, RPS6KA3, HCFC1, MID2, ACSL4, ZNF711
organelle organization (GO:0006996) 2.028DDX3X, IQSEC2, HCFC1, USP9X, SYP, BRWD3, ZDHHC15, KIF4A
cellular protein metabolic process (GO:0044267) 1.638ARHGEF6, RPS6KA3, FTSJ1, HCFC1, USP9X, MID2, ZDHHC15, PAK3
nucleobase-containing compound metabolic process (GO:0006139) 1.358THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
protein metabolic process (GO:0019538) 1.458ARHGEF6, RPS6KA3, FTSJ1, HCFC1, USP9X, MID2, ZDHHC15, PAK3
cellular aromatic compound metabolic process (GO:0006725) 1.38THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
regulation of response to stimulus (GO:0048583) 1.548ARHGEF6, GDI1, DDX3X, RPS6KA3, MID2, IQSEC2, SYP, PAK3
biosynthetic process (GO:0009058) 1.328THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ACSL4, ZNF711
regulation of cellular component organization (GO:0051128) 2.018GDI1, IL1RAPL1, DDX3X, RPS6KA3, HCFC1, BRWD3, ACSL4, PAK3
cellular biosynthetic process (GO:0044249) 1.378THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ACSL4, ZNF711
macromolecule modification (GO:0043412) 1.738ARHGEF6, RPS6KA3, FTSJ1, HCFC1, USP9X, MID2, ZDHHC15, PAK3
nitrogen compound metabolic process (GO:0006807) 1.138THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
organic substance biosynthetic process (GO:1901576) 1.348THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ACSL4, ZNF711
cellular nitrogen compound metabolic process (GO:0034641) 1.228THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
response to chemical (GO:0042221) 1.988GDI1, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, ACSL4, PAK3
regulation of molecular function (GO:0065009) 1.788ARHGEF6, GDI1, DLG3, RPS6KA3, MID2, IQSEC2, DDX3X, PAK3
organic cyclic compound metabolic process (GO:1901360) 1.268THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
heterocycle metabolic process (GO:0046483) 1.318THOC2, DLG3, FTSJ1, HCFC1, ARX, ZNF81, DDX3X, ZNF711
RNA metabolic process (GO:0016070) 1.597THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ZNF711
regulation of catalytic activity (GO:0050790) 1.977GDI1, ARHGEF6, DLG3, RPS6KA3, IQSEC2, DDX3X, PAK3
negative regulation of metabolic process (GO:0009892) 1.937DLG3, RPS6KA3, HCFC1, USP9X, MID2, ARX, DDX3X
regulation of signal transduction (GO:0009966) 1.847GDI1, ARHGEF6, DDX3X, MID2, IQSEC2, SYP, PAK3
anatomical structure development (GO:0048856) 1.587THOC2, ARX, DLG3, RPS6KA3, KIAA2022, ACSL4, PAK3
negative regulation of cellular metabolic process (GO:0031324) 2.017DLG3, RPS6KA3, HCFC1, USP9X, MID2, ARX, DDX3X
cellular protein modification process (GO:0006464) 1.797ARHGEF6, RPS6KA3, HCFC1, USP9X, MID2, ZDHHC15, PAK3
nucleic acid metabolic process (GO:0090304) 1.467THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ZNF711
macromolecule biosynthetic process (GO:0009059) 1.617THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ZNF711
protein modification process (GO:0036211) 1.797ARHGEF6, RPS6KA3, HCFC1, USP9X, MID2, ZDHHC15, PAK3
regulation of signaling (GO:0023051) 1.727GDI1, ARHGEF6, DDX3X, MID2, IQSEC2, SYP, PAK3
cellular nitrogen compound biosynthetic process (GO:0044271) 1.597THOC2, DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ZNF711
regulation of cell communication (GO:0010646) 1.737GDI1, ARHGEF6, DDX3X, MID2, IQSEC2, SYP, PAK3
regulation of hydrolase activity (GO:0051336) 2.536ARHGEF6, GDI1, DLG3, RPS6KA3, IQSEC2, DDX3X
cellular response to stimulus (GO:0051716) 1.976ARHGEF6, DDX3X, RPS6KA3, HCFC1, SYP, PAK3
RNA biosynthetic process (GO:0032774) 1.846THOC2, DDX3X, HCFC1, ARX, ZNF81, ZNF711
positive regulation of metabolic process (GO:0009893) 1.746DDX3X, RPS6KA3, HCFC1, PAK3, ARX, ZNF711
positive regulation of macromolecule metabolic process (GO:0010604) 1.816DDX3X, RPS6KA3, HCFC1, PAK3, ARX, ZNF711
cellular macromolecule biosynthetic process (GO:0034645) 1.666DDX3X, FTSJ1, HCFC1, ARX, ZNF81, ZNF711
regulation of transcription from RNA polymerase II promoter (GO:0006357) 2.246DDX3X, RPS6KA3, HCFC1, USP9X, BRWD3, ARX
positive regulation of molecular function (GO:0044093) 2.236GDI1, ARHGEF6, DDX3X, MID2, IQSEC2, PAK3
aromatic compound biosynthetic process (GO:0019438) 1.76THOC2, DDX3X, HCFC1, ARX, ZNF81, ZNF711
nucleobase-containing compound biosynthetic process (GO:0034654) 1.726THOC2, DDX3X, HCFC1, ARX, ZNF81, ZNF711
negative regulation of macromolecule metabolic process (GO:0010605) 2.016DDX3X, RPS6KA3, HCFC1, USP9X, MID2, ARX
intracellular signal transduction (GO:0035556) 2.396RAB39B, ARHGEF6, GDI1, DDX3X, RPS6KA3, PAK3
regulation of intracellular signal transduction (GO:1902531) 2.316ARHGEF6, GDI1, DDX3X, MID2, IQSEC2, PAK3
organic cyclic compound biosynthetic process (GO:1901362) 1.666THOC2, DDX3X, HCFC1, ARX, ZNF81, ZNF711
heterocycle biosynthetic process (GO:0018130) 1.76THOC2, DDX3X, HCFC1, ARX, ZNF81, ZNF711
protein localization (GO:0008104) 2.365DDX3X, MID2, DLG3, GDI1, RAB39B
regulation of multicellular organismal process (GO:0051239) 1.875GDI1, DDX3X, PAK3, IL1RAPL1, ARX
negative regulation of biosynthetic process (GO:0009890) 2.475HCFC1, DDX3X, MID2, USP9X, ARX
positive regulation of biosynthetic process (GO:0009891) 2.295DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
negative regulation of cellular biosynthetic process (GO:0031327) 2.495HCFC1, USP9X, DDX3X, MID2, ARX
positive regulation of cellular metabolic process (GO:0031325) 1.815DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
negative regulation of gene expression (GO:0010629) 2.485HCFC1, DDX3X, MID2, USP9X, ARX
positive regulation of gene expression (GO:0010628) 2.355HCFC1, DDX3X, RPS6KA3, ZNF711, ARX
cell surface receptor signaling pathway (GO:0007166) 2.095GRIA3, USP9X, TSPAN7, DDX3X, PAK3
positive regulation of catalytic activity (GO:0043085) 2.45IQSEC2, GDI1, DDX3X, ARHGEF6, PAK3
single-organism metabolic process (GO:0044710) 1.635DLG3, PAK3, GDI1, ARHGEF6, ACSL4
cellular developmental process (GO:0048869) 1.825THOC2, ACSL4, PAK3, IL1RAPL1, ARX
positive regulation of cellular biosynthetic process (GO:0031328) 2.35DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
nucleic acid-templated transcription (GO:0097659) 1.915HCFC1, ZNF711, ZNF81, DDX3X, ARX
macromolecule localization (GO:0033036) 2.345DDX3X, MID2, DLG3, GDI1, RAB39B
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.355DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
regulation of developmental process (GO:0050793) 2.15IL1RAPL1, BRWD3, GDI1, ARX, PAK3
negative regulation of nitrogen compound metabolic process (GO:0051172) 2.475HCFC1, DDX3X, MID2, USP9X, ARX
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.295DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
response to organic substance (GO:0010033) 2.25RPS6KA3, ACSL4, SYP, PAK3, HCFC1
cellular localization (GO:0051641) 2.325THOC2, DDX3X, KIF4A, DLG3, MID2
immune system process (GO:0002376) 2.295DDX3X, RPS6KA3, KIF4A, MID2, PAK3
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.395DDX3X, RPS6KA3, HCFC1, ZNF711, PAK3
transcription, DNA-templated (GO:0006351) 1.915HCFC1, ZNF711, ZNF81, DDX3X, ARX
negative regulation of macromolecule biosynthetic process (GO:0010558) 2.535HCFC1, DDX3X, MID2, USP9X, ARX
regulation of cell morphogenesis (GO:0022604) 3.44BRWD3, IL1RAPL1, GDI1, PAK3
cellular component assembly (GO:0022607) 2.144DDX3X, KIF4A, IL1RAPL1, ARHGEF6
positive regulation of growth (GO:0045927) 4.254DDX3X, RPS6KA3, ACSL4, ARX
regulation of anatomical structure morphogenesis (GO:0022603) 2.794BRWD3, IL1RAPL1, GDI1, PAK3
cell differentiation (GO:0030154) 2.144THOC2, ACSL4, IL1RAPL1, ARX
cellular response to chemical stimulus (GO:0070887) 2.574DDX3X, SYP, PAK3, HCFC1
regulation of cell differentiation (GO:0045595) 2.424RPS6KA3, GDI1, IL1RAPL1, PAK3
regulation of cell death (GO:0010941) 2.434DDX3X, RPS6KA3, PAK3, ARHGEF6
regulation of apoptotic process (GO:0042981) 2.54DDX3X, RPS6KA3, PAK3, ARHGEF6
cell cycle (GO:0007049) 3.144USP9X, RPS6KA3, PAK3, HCFC1
positive regulation of hydrolase activity (GO:0051345) 2.914IQSEC2, DDX3X, GDI1, ARHGEF6
positive regulation of multicellular organismal process (GO:0051240) 2.494DDX3X, PAK3, IL1RAPL1, ARX
negative regulation of cellular macromolecule biosynthetic process (GO:2000113) 2.64HCFC1, USP9X, DDX3X, ARX
interspecies interaction between organisms (GO:0044419) 3.084THOC2, DDX3X, TSPAN7, HCFC1
regulation of programmed cell death (GO:0043067) 2.494DDX3X, RPS6KA3, PAK3, ARHGEF6
organic substance transport (GO:0071702) 2.154THOC2, ACSL4, RAB39B, GDI1
regulation of biological quality (GO:0065008) 1.684SYP, BRWD3, PAK3, HCFC1
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.564DDX3X, RPS6KA3, HCFC1, ZNF711
negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 2.554HCFC1, USP9X, MID2, ARX
ion transport (GO:0006811) 2.664GRIA3, DLG3, ACSL4, IL1RAPL1
negative regulation of RNA biosynthetic process (GO:1902679) 2.74HCFC1, USP9X, MID2, ARX
response to stress (GO:0006950) 1.84DDX3X, RPS6KA3, MID2, ARHGEF6
multi-organism cellular process (GO:0044764) 3.144THOC2, DDX3X, TSPAN7, HCFC1
positive regulation of transcription, DNA-templated (GO:0045893) 2.564DDX3X, RPS6KA3, HCFC1, ZNF711
system development (GO:0048731) 2.924DLG3, RPS6KA3, KIAA2022, ARX
multi-organism process (GO:0051704) 2.654THOC2, DDX3X, TSPAN7, HCFC1
negative regulation of RNA metabolic process (GO:0051253) 2.664HCFC1, USP9X, MID2, ARX
positive regulation of RNA metabolic process (GO:0051254) 2.514DDX3X, RPS6KA3, HCFC1, ZNF711
positive regulation of RNA biosynthetic process (GO:1902680) 2.544DDX3X, RPS6KA3, HCFC1, ZNF711
phosphate-containing compound metabolic process (GO:0006796) 2.164DLG3, RPS6KA3, PAK3, ARHGEF6
viral process (GO:0016032) 3.154THOC2, DDX3X, TSPAN7, HCFC1
phosphorus metabolic process (GO:0006793) 2.154DLG3, RPS6KA3, PAK3, ARHGEF6
symbiosis, encompassing mutualism through parasitism (GO:0044403) 3.154THOC2, DDX3X, TSPAN7, HCFC1
regulation of growth (GO:0040008) 3.264DDX3X, RPS6KA3, ACSL4, ARX
single-multicellular organism process (GO:0044707) 1.783PAK3, ARX, KIAA2022
regulation of transport (GO:0051049) 2.243ACSL4, IL1RAPL1, GDI1
positive regulation of response to stimulus (GO:0048584) 2.183RPS6KA3, PAK3, MID2
movement of cell or subcellular component (GO:0006928) 2.613USP9X, KIF4A, ARX
membrane organization (GO:0061024) 3.043DLG3, SYP, IL1RAPL1
positive regulation of cell death (GO:0010942) 3.323DDX3X, PAK3, ARHGEF6
regulation of GTPase activity (GO:0043087) 3.213IQSEC2, GDI1, ARHGEF6
regulation of cell projection organization (GO:0031344) 3.383PAK3, IL1RAPL1, GDI1
regulation of neurogenesis (GO:0050767) 3.213PAK3, IL1RAPL1, GDI1
negative regulation of catalytic activity (GO:0043086) 3.03DLG3, RPS6KA3, DDX3X
negative regulation of hydrolase activity (GO:0051346) 3.743DLG3, RPS6KA3, DDX3X
negative regulation of transcription from RNA polymerase II promoter (GO:0000122) 3.123USP9X, HCFC1, ARX
regulation of protein metabolic process (GO:0051246) 1.933DDX3X, RPS6KA3, PAK3
regulation of cell development (GO:0060284) 3.013PAK3, IL1RAPL1, GDI1
multicellular organism development (GO:0007275) 2.543PAK3, KIAA2022, ARX
positive regulation of apoptotic process (GO:0043065) 3.383DDX3X, PAK3, ARHGEF6
regulation of neuron differentiation (GO:0045664) 3.393PAK3, IL1RAPL1, GDI1
cellular response to organic substance (GO:0071310) 2.783SYP, PAK3, HCFC1
regulation of cell morphogenesis involved in differentiation (GO:0010769) 3.913PAK3, IL1RAPL1, GDI1
negative regulation of molecular function (GO:0044092) 2.743DLG3, RPS6KA3, DDX3X
positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 2.813DDX3X, RPS6KA3, HCFC1
positive regulation of programmed cell death (GO:0043068) 3.383DDX3X, PAK3, ARHGEF6
regulation of small GTPase mediated signal transduction (GO:0051056) 4.083IQSEC2, GDI1, ARHGEF6
protein phosphorylation (GO:0006468) 2.893RPS6KA3, PAK3, ARHGEF6
multicellular organismal process (GO:0032501) 1.453PAK3, ARX, KIAA2022
negative regulation of transport (GO:0051051) 3.63ACSL4, IL1RAPL1, GDI1
cellular protein localization (GO:0034613) 3.113DDX3X, DLG3, MID2
phosphorylation (GO:0016310) 2.633RPS6KA3, PAK3, ARHGEF6
negative regulation of nucleic acid-templated transcription (GO:1903507) 2.713USP9X, HCFC1, ARX
establishment of protein localization (GO:0045184) 2.533ZDHHC15, RAB39B, GDI1
ion transmembrane transport (GO:0034220) 3.083GRIA3, DLG3, IL1RAPL1
regulation of cell growth (GO:0001558) 3.753DDX3X, RPS6KA3, ACSL4
single-organism membrane organization (GO:0044802) 3.193DLG3, SYP, IL1RAPL1
regulation of neuron projection development (GO:0010975) 3.693PAK3, IL1RAPL1, GDI1
regulation of protein complex assembly (GO:0043254) 3.833DDX3X, PAK3, HCFC1
regulation of localization (GO:0032879) 1.943ACSL4, IL1RAPL1, GDI1
transmembrane transport (GO:0055085) 2.723GRIA3, DLG3, IL1RAPL1
single-organism localization (GO:1902578) 2.093DLG3, ACSL4, KIF4A
positive regulation of GTPase activity (GO:0043547) 3.283IQSEC2, GDI1, ARHGEF6
positive regulation of cell differentiation (GO:0045597) 3.013RPS6KA3, PAK3, IL1RAPL1
positive regulation of cell growth (GO:0030307) 4.733DDX3X, RPS6KA3, ACSL4
regulation of cellular protein metabolic process (GO:0032268) 1.993DDX3X, RPS6KA3, PAK3
vesicle-mediated transport (GO:0016192) 2.723SYP, KIF4A, RAB39B
response to external stimulus (GO:0009605) 2.553DDX3X, RPS6KA3, ACSL4
positive regulation of developmental process (GO:0051094) 2.773PAK3, IL1RAPL1, ARX
cellular macromolecule localization (GO:0070727) 3.13DDX3X, DLG3, MID2
nervous system development (GO:0007399) 3.533DLG3, KIAA2022, ARX
regulation of cellular component biogenesis (GO:0044087) 3.083DDX3X, PAK3, HCFC1
single-organism organelle organization (GO:1902589) 2.683ZDHHC15, SYP, IQSEC2
regulation of nervous system development (GO:0051960) 3.13PAK3, IL1RAPL1, GDI1
regulation of multicellular organismal development (GO:2000026) 2.313PAK3, IL1RAPL1, GDI1
cellular response to stress (GO:0033554) 2.513DDX3X, RPS6KA3, ARHGEF6
negative regulation of transcription, DNA-templated (GO:0045892) 2.753USP9X, HCFC1, ARX
regulation of phosphate metabolic process (GO:0019220) 2.352DLG3, PAK3
regulation of secretion (GO:0051046) 3.22ACSL4, IL1RAPL1
negative regulation of secretion (GO:0051048) 4.442ACSL4, IL1RAPL1
positive regulation of defense response (GO:0031349) 3.832RPS6KA3, PAK3
small molecule metabolic process (GO:0044281) 2.382DLG3, ACSL4
enzyme linked receptor protein signaling pathway (GO:0007167) 3.242USP9X, PAK3
regulation of defense response (GO:0031347) 3.112RPS6KA3, PAK3
positive regulation of cell projection organization (GO:0031346) 3.992PAK3, IL1RAPL1
positive regulation of cell cycle (GO:0045787) 3.942DDX3X, HCFC1
response to external biotic stimulus (GO:0043207) 3.132DDX3X, RPS6KA3
synaptic vesicle maturation (GO:0016188) 7.652ZDHHC15, SYP
posttranscriptional regulation of gene expression (GO:0010608) 3.642DDX3X, RPS6KA3
protein modification by small protein conjugation or removal (GO:0070647) 2.952USP9X, MID2
positive regulation of neuron differentiation (GO:0045666) 3.982PAK3, IL1RAPL1
positive regulation of cell development (GO:0010720) 3.572PAK3, IL1RAPL1
regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281) 4.432DDX3X, RPS6KA3
dendritic spine development (GO:0060996) 7.162ACSL4, PAK3
regulation of cell proliferation (GO:0042127) 2.412DLG3, ARX
negative regulation of cell death (GO:0060548) 2.952DDX3X, RPS6KA3
regulation of proteolysis (GO:0030162) 3.22DDX3X, RPS6KA3
positive regulation of neuron projection development (GO:0010976) 4.262PAK3, IL1RAPL1
response to biotic stimulus (GO:0009607) 3.092DDX3X, RPS6KA3
single organism signaling (GO:0044700) 3.252GRIA3, DLG3
single organism reproductive process (GO:0044702) 2.732USP9X, ACSL4
organonitrogen compound metabolic process (GO:1901564) 2.322DLG3, FTSJ1
cell motility (GO:0048870) 3.022USP9X, ARX
vesicle organization (GO:0016050) 4.132ZDHHC15, SYP
anterograde trans-synaptic signaling (GO:0098916) 3.982GRIA3, DLG3
negative regulation of peptidase activity (GO:0010466) 4.222DDX3X, RPS6KA3
neuron migration (GO:0001764) 5.02USP9X, ARX
developmental maturation (GO:0021700) 4.72ZDHHC15, SYP
protein acylation (GO:0043543) 4.652ZDHHC15, HCFC1
immune response-regulating signaling pathway (GO:0002764) 3.722RPS6KA3, PAK3
positive regulation of immune system process (GO:0002684) 2.962RPS6KA3, PAK3
regulation of immune system process (GO:0002682) 2.52RPS6KA3, PAK3
signal transduction by protein phosphorylation (GO:0023014) 3.792PAK3, ARHGEF6
cell migration (GO:0016477) 3.122USP9X, ARX
positive regulation of cellular component organization (GO:0051130) 2.682PAK3, IL1RAPL1
regulation of viral process (GO:0050792) 3.892DDX3X, MID2
defense response (GO:0006952) 2.782DDX3X, MID2
programmed cell death (GO:0012501) 3.12DDX3X, ARHGEF6
regulation of multi-organism process (GO:0043900) 3.62DDX3X, MID2
immune response (GO:0006955) 2.862DDX3X, MID2
chromosome segregation (GO:0007059) 5.062USP9X, DDX3X
immune response-activating signal transduction (GO:0002757) 3.82RPS6KA3, PAK3
intracellular transport (GO:0046907) 2.672THOC2, KIF4A
regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903) 3.822DDX3X, MID2
regulation of response to stress (GO:0080134) 2.532RPS6KA3, PAK3
innate immune response-activating signal transduction (GO:0002758) 4.452RPS6KA3, PAK3
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154) 5.292DDX3X, RPS6KA3
regulation of dendrite morphogenesis (GO:0048814) 5.412PAK3, IL1RAPL1
positive regulation of signal transduction (GO:0009967) 2.52PAK3, MID2
synaptic signaling (GO:0099536) 3.982GRIA3, DLG3
trans-synaptic signaling (GO:0099537) 3.982GRIA3, DLG3
synapse organization (GO:0050808) 4.872PAK3, RAB39B
MAPK cascade (GO:0000165) 3.912PAK3, ARHGEF6
establishment of localization in cell (GO:0051649) 2.472THOC2, KIF4A
regulation of Ras protein signal transduction (GO:0046578) 4.492IQSEC2, ARHGEF6
negative regulation of cellular component organization (GO:0051129) 3.352DDX3X, GDI1
positive regulation of signaling (GO:0023056) 2.412PAK3, MID2
negative regulation of endopeptidase activity (GO:0010951) 4.262DDX3X, RPS6KA3
signaling (GO:0023052) 3.252GRIA3, DLG3
positive regulation of intracellular signal transduction (GO:1902533) 2.952PAK3, MID2
positive regulation of cell communication (GO:0010647) 2.412PAK3, MID2
anatomical structure morphogenesis (GO:0009653) 2.532DLG3, PAK3
response to organic cyclic compound (GO:0014070) 3.072PAK3, HCFC1
negative regulation of protein metabolic process (GO:0051248) 2.822DDX3X, RPS6KA3
regulation of viral life cycle (GO:1903900) 4.62DDX3X, MID2
positive regulation of protein metabolic process (GO:0051247) 2.432DDX3X, PAK3
positive regulation of neurogenesis (GO:0050769) 3.772PAK3, IL1RAPL1
macromolecular complex subunit organization (GO:0043933) 2.142DDX3X, HCFC1
positive regulation of cellular protein metabolic process (GO:0032270) 2.492DDX3X, PAK3
multicellular organismal reproductive process (GO:0048609) 3.352USP9X, ACSL4
regulation of cellular amide metabolic process (GO:0034248) 3.882DDX3X, RPS6KA3
positive regulation of dendrite morphogenesis (GO:0050775) 6.262PAK3, IL1RAPL1
negative regulation of cellular protein metabolic process (GO:0032269) 2.882DDX3X, RPS6KA3
regulation of immune response (GO:0050776) 2.982RPS6KA3, PAK3
regulation of dendrite development (GO:0050773) 4.932PAK3, IL1RAPL1
cellular response to organic cyclic compound (GO:0071407) 3.932PAK3, HCFC1
positive regulation of immune response (GO:0050778) 3.42RPS6KA3, PAK3
protein localization to organelle (GO:0033365) 3.572DDX3X, MID2
positive regulation of cell morphogenesis involved in differentiation (GO:0010770) 4.652PAK3, IL1RAPL1
negative regulation of proteolysis (GO:0045861) 3.982DDX3X, RPS6KA3
cell projection organization (GO:0030030) 3.142PAK3, ARHGEF6
mitotic cell cycle process (GO:1903047) 3.122USP9X, KIF4A
cell cycle process (GO:0022402) 2.752USP9X, KIF4A
protein transport (GO:0015031) 2.622RAB39B, GDI1
cell death (GO:0008219) 3.052DDX3X, ARHGEF6
positive regulation of dendrite development (GO:1900006) 5.572PAK3, IL1RAPL1
positive regulation of nervous system development (GO:0051962) 3.642PAK3, IL1RAPL1
regulation of cysteine-type endopeptidase activity (GO:2000116) 4.372DDX3X, RPS6KA3
negative regulation of cysteine-type endopeptidase activity (GO:2000117) 5.252DDX3X, RPS6KA3
negative regulation of apoptotic process (GO:0043066) 3.042DDX3X, RPS6KA3
activation of innate immune response (GO:0002218) 4.412RPS6KA3, PAK3
negative regulation of programmed cell death (GO:0043069) 3.022DDX3X, RPS6KA3
positive regulation of innate immune response (GO:0045089) 4.222RPS6KA3, PAK3
regulation of innate immune response (GO:0045088) 3.862RPS6KA3, PAK3
neuron differentiation (GO:0030182) 4.172ACSL4, IL1RAPL1
regulation of peptidase activity (GO:0052547) 3.752DDX3X, RPS6KA3
regulation of endopeptidase activity (GO:0052548) 3.82DDX3X, RPS6KA3
innate immune response (GO:0045087) 3.552DDX3X, MID2
apoptotic process (GO:0006915) 3.142DDX3X, ARHGEF6
regulation of phosphorus metabolic process (GO:0051174) 2.352DLG3, PAK3
reproductive process (GO:0022414) 2.552USP9X, ACSL4
single-organism transport (GO:0044765) 2.182ACSL4, KIF4A
chemical synaptic transmission (GO:0007268) 3.982GRIA3, DLG3
cell-cell signaling (GO:0007267) 3.352GRIA3, DLG3
cell communication (GO:0007154) 3.042GRIA3, DLG3
small GTPase mediated signal transduction (GO:0007264) 3.852RAB39B, GDI1
locomotion (GO:0040011) 2.912USP9X, ARX
cytoskeleton organization (GO:0007010) 3.222IQSEC2, BRWD3
regulation of cell cycle (GO:0051726) 2.932DDX3X, HCFC1
activation of immune response (GO:0002253) 3.672RPS6KA3, PAK3
regulation of translation (GO:0006417) 3.962DDX3X, RPS6KA3
single-organism cellular localization (GO:1902580) 3.162DLG3, KIF4A
RNA processing (GO:0006396) 3.012THOC2, FTSJ1

NET-GE enrichment

Term New enriched termICP valueGenes
synaptic vesicle maturation (GO:0016188) -7.650.049ZDHHC15, SYP
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cell part (GO:0044464) 0.1125ARHGEF6, GDI1, RPS6KA3, ARX, ZNF81, ACSL4, THOC2, IL1RAPL1, DLG3, SYP, KIF4A, TSPAN7, RAB39B, GRIA3, FTSJ1, MID2, IQSEC2, KIAA2022, PAK3, DDX3X, HCFC1, USP9X, BRWD3, ZDHHC15, ZNF711
intracellular part (GO:0044424) 0.2824ARHGEF6, GDI1, RPS6KA3, ARX, ZNF81, ACSL4, THOC2, IL1RAPL1, DLG3, SYP, KIF4A, RAB39B, GRIA3, FTSJ1, MID2, IQSEC2, KIAA2022, PAK3, DDX3X, HCFC1, USP9X, BRWD3, ZDHHC15, ZNF711
intracellular organelle (GO:0043229) 0.5119THOC2, PAK3, ZNF81, GDI1, KIAA2022, RAB39B, ACSL4, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, KIF4A, ARX, BRWD3, ZDHHC15, DLG3, ZNF711, MID2
organelle (GO:0043226) 0.419THOC2, PAK3, ZNF81, GDI1, KIAA2022, RAB39B, ACSL4, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, KIF4A, ARX, BRWD3, ZDHHC15, DLG3, ZNF711, MID2
membrane-bounded organelle (GO:0043227) 0.4717THOC2, PAK3, GDI1, KIAA2022, RAB39B, ACSL4, DDX3X, RPS6KA3, HCFC1, SYP, KIF4A, ARX, BRWD3, ZDHHC15, ZNF81, ZNF711, MID2
intracellular membrane-bounded organelle (GO:0043231) 0.616THOC2, PAK3, GDI1, KIAA2022, RAB39B, ACSL4, DDX3X, RPS6KA3, HCFC1, SYP, KIF4A, ARX, BRWD3, ZDHHC15, ZNF81, ZNF711
cytoplasm (GO:0005737) 1.0113GDI1, IL1RAPL1, PAK3, RPS6KA3, DLG3, FTSJ1, IQSEC2, HCFC1, USP9X, MID2, ACSL4, DDX3X, KIF4A
cytoplasmic part (GO:0044444) 0.8213GDI1, RAB39B, ARHGEF6, GRIA3, DDX3X, RPS6KA3, HCFC1, USP9X, SYP, PAK3, ZDHHC15, ACSL4, KIF4A
membrane (GO:0016020) 0.6813TSPAN7, IL1RAPL1, RAB39B, ACSL4, GRIA3, DDX3X, HCFC1, USP9X, SYP, PAK3, ZDHHC15, DLG3, KIF4A
neuron part (GO:0097458) 2.6410GDI1, IL1RAPL1, RAB39B, GRIA3, DLG3, HCFC1, USP9X, SYP, ACSL4, KIF4A
nucleus (GO:0005634) 1.0710THOC2, KIAA2022, DDX3X, RPS6KA3, HCFC1, BRWD3, KIF4A, ARX, ZNF81, ZNF711
intracellular organelle part (GO:0044446) 0.819THOC2, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, MID2, ACSL4, KIF4A
organelle part (GO:0044422) 0.799THOC2, GRIA3, DDX3X, RPS6KA3, HCFC1, SYP, MID2, ACSL4, KIF4A
cell projection (GO:0042995) 2.478IL1RAPL1, GDI1, RAB39B, ARHGEF6, GRIA3, HCFC1, USP9X, SYP
protein complex (GO:0043234) 1.517THOC2, GDI1, GRIA3, DLG3, HCFC1, DDX3X, KIF4A
membrane part (GO:0044425) 0.957TSPAN7, IL1RAPL1, GRIA3, DLG3, SYP, ZDHHC15, ACSL4
macromolecular complex (GO:0032991) 1.357THOC2, GDI1, GRIA3, DLG3, HCFC1, DDX3X, KIF4A
vesicle (GO:0031982) 1.647RAB39B, DDX3X, MID2, SYP, ZDHHC15, ACSL4, ZNF711
cytosol (GO:0005829) 1.686ARHGEF6, GDI1, RPS6KA3, USP9X, PAK3, KIF4A
intracellular non-membrane-bounded organelle (GO:0043232) 1.766GRIA3, DLG3, MID2, ACSL4, DDX3X, KIF4A
integral component of membrane (GO:0016021) 1.146TSPAN7, IL1RAPL1, GRIA3, SYP, ZDHHC15, ACSL4
membrane-bounded vesicle (GO:0031988) 1.716DDX3X, MID2, SYP, ZDHHC15, ACSL4, ZNF711
non-membrane-bounded organelle (GO:0043228) 1.766GRIA3, DLG3, MID2, ACSL4, DDX3X, KIF4A
nuclear part (GO:0044428) 1.556THOC2, GRIA3, DDX3X, RPS6KA3, HCFC1, KIF4A
neuron projection (GO:0043005) 3.126IL1RAPL1, RAB39B, GDI1, GRIA3, HCFC1, SYP
extracellular region part (GO:0044421) 1.576ACSL4, DDX3X, MID2, ZDHHC15, DLG3, ZNF711
intrinsic component of membrane (GO:0031224) 1.136TSPAN7, IL1RAPL1, GRIA3, SYP, ZDHHC15, ACSL4
extracellular organelle (GO:0043230) 1.895ZNF711, ZDHHC15, DDX3X, MID2, ACSL4
extracellular exosome (GO:0070062) 1.895ZNF711, ZDHHC15, DDX3X, MID2, ACSL4
cell projection part (GO:0044463) 2.975GRIA3, DLG3, SYP, USP9X, KIF4A
intracellular (GO:0005622) 2.375ZNF81, MID2, GDI1, ARHGEF6, RAB39B
nucleoplasm (GO:0005654) 1.895THOC2, GRIA3, RPS6KA3, KIF4A, HCFC1
plasma membrane (GO:0005886) 1.395GRIA3, DLG3, PAK3, RAB39B, IL1RAPL1
extracellular vesicle (GO:1903561) 1.895ZNF711, ZDHHC15, DDX3X, MID2, ACSL4
plasma membrane part (GO:0044459) 1.955GRIA3, DLG3, SYP, TSPAN7, IL1RAPL1
synaptic membrane (GO:0097060) 4.224GRIA3, DLG3, SYP, IL1RAPL1
plasma membrane region (GO:0098590) 2.974GRIA3, DLG3, SYP, IL1RAPL1
organelle membrane (GO:0031090) 1.974GRIA3, DDX3X, SYP, ACSL4
bounding membrane of organelle (GO:0098588) 2.394GRIA3, DDX3X, SYP, ACSL4
cell body (GO:0044297) 3.744GRIA3, DLG3, ACSL4, HCFC1
synapse part (GO:0044456) 3.424GRIA3, DLG3, SYP, IL1RAPL1
neuronal cell body (GO:0043025) 3.94GRIA3, DLG3, ACSL4, HCFC1
whole membrane (GO:0098805) 2.854GRIA3, DDX3X, SYP, ACSL4
Golgi apparatus (GO:0005794) 2.73ZDHHC15, RAB39B, GDI1
mitochondrion (GO:0005739) 2.423DDX3X, ACSL4, HCFC1
postsynaptic membrane (GO:0045211) 4.473GRIA3, DLG3, IL1RAPL1
nucleoplasm part (GO:0044451) 3.223THOC2, DDX3X, HCFC1
dendrite (GO:0030425) 3.923GRIA3, HCFC1, IL1RAPL1
axon part (GO:0033267) 4.43GRIA3, SYP, KIF4A
cell junction (GO:0030054) 2.753GRIA3, DLG3, SYP
synapse (GO:0045202) 3.583GRIA3, DLG3, SYP
supramolecular fiber (GO:0099512) 3.312KIF4A, MID2
polymeric cytoskeletal fiber (GO:0099513) 3.312KIF4A, MID2
nuclear speck (GO:0016607) 4.522THOC2, DDX3X
site of polarized growth (GO:0030427) 4.852USP9X, DLG3
growth cone (GO:0030426) 4.892DLG3, USP9X
postsynaptic specialization (GO:0099572) 4.772GRIA3, DLG3
axon (GO:0030424) 4.152HCFC1, IL1RAPL1
ion channel complex (GO:0034702) 4.182GRIA3, DLG3
AMPA glutamate receptor complex (GO:0032281) 6.472GRIA3, DLG3
microtubule (GO:0005874) 3.812KIF4A, MID2
cytoskeleton (GO:0005856) 2.552KIF4A, MID2
nuclear body (GO:0016604) 3.942THOC2, DDX3X
plasma membrane receptor complex (GO:0098802) 4.632GRIA3, DLG3
cytoplasmic vesicle part (GO:0044433) 3.412GRIA3, SYP
cytoskeletal part (GO:0044430) 2.492KIF4A, MID2
organelle outer membrane (GO:0031968) 4.632DDX3X, ACSL4
transmembrane transporter complex (GO:1902495) 4.062GRIA3, DLG3
ionotropic glutamate receptor complex (GO:0008328) 5.972GRIA3, DLG3
transporter complex (GO:1990351) 4.042GRIA3, DLG3
mitochondrial membrane (GO:0031966) 3.312DDX3X, ACSL4
cytoplasmic vesicle membrane (GO:0030659) 3.672GRIA3, SYP
postsynaptic density (GO:0014069) 4.772GRIA3, DLG3
vesicle membrane (GO:0012506) 3.632GRIA3, SYP
receptor complex (GO:0043235) 4.012GRIA3, DLG3
terminal bouton (GO:0043195) 5.632GRIA3, SYP
dendritic shaft (GO:0043198) 6.162GRIA3, DLG3
midbody (GO:0030496) 4.952KIF4A, GDI1
outer membrane (GO:0019867) 4.62DDX3X, ACSL4
plasma membrane protein complex (GO:0098797) 3.552GRIA3, DLG3
membrane protein complex (GO:0098796) 2.842GRIA3, DLG3
(GO:0098878) 5.972GRIA3, DLG3
mitochondrial outer membrane (GO:0005741) 4.762DDX3X, ACSL4
presynapse (GO:0098793) 4.972GRIA3, SYP
mitochondrial part (GO:0044429) 2.922DDX3X, ACSL4

NET-GE enrichment

Term New enriched termICP valueGenes
neuron part (GO:0097458) -2.640.001GDI1, IL1RAPL1, DLG3, HCFC1, USP9X, SYP, ACSL4, GRIA4