Disease table of BRACHYDACTYLY, TYPE A2 OMIM ID: 112600

Gene-disease associations table

GeneAssociated with BRACHYDACTYLY, TYPE A2 inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
BMPR1BClinVar, OMIM, HUMSAVARHGNC link4q22.33616849, 609441, 112600
BMP2ClinVar, OMIMHGNC link20p12.32PS235200, 112600
GDF5ClinVar, OMIM, HUMSAVARHGNC link20q11.229PS186500, 112600, 201250, 228900, 615072, 612400, PS185800, 113100, 200700

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
202BMP2, GDF5
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
BMP2YES4DNMT1, HEY1, NFKB1, RELA0
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
BMPR1BBMP2Yes3BMPR2, BMPR1A, BMPR1B
BMPR1BGDF5Yes3BMPR2, BMPR1A, BMPR1B
BMP2GDF5No3BMPR2, BMPR1A, BMPR1B

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
BMPR1BBMP2Yesactivation, binding37BMPR1A, CHRDL1, ACVR2B, SMAD4, ZFYVE16, SMAD6, BMP6, BMP7, BAMBI, BMP5, BMP4, NOG, SMAD7, ACVR2A, MAP3K7, SMAD3, SMAD5, CHRD, RGMB, SMURF1, BMPR2, SMAD2, SMAD9, PPP1R15A, AMHR2, TAB1, AHSG, RGMA, GREM1, XIAP, PPP1CA, GDF5, FST, TAB2, SMAD1, CER1, SOSTDC1
BMPR1BGDF5Yesactivation, binding11BMPR1A, BMP4, AMHR2, ACVR2B, ACVR2A, BMP7, BMP2, SMAD5, CHRD, NOG, BMPR2
BMP2GDF5Yesactivation, binding15BMPR2, BMPR1A, RUNX2, BMP4, AMHR2, ACVR2B, BMP10, ACVR2A, BMPR1B, BMP7, SMAD5, CHRD, NOG, ACAN, ACVR1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Gene1Gene2InteractionNumber of common interactorsCommon genes in interaction
BMP2GDF5No1BMPR1A

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from manually curated literature
Gene1Gene2Direct interactionMore information
BMP2BMPR1Byes, they interactBMPR1B positively regulates chondrocyte differentiation and interact with BMP2 (ligand-receptor). [Uniprot ]
BMP2GDF5No
BMPR1BGDF5yes, they interactBMPR1B interacts with high affinity with GDF5. [UniProt ]
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
TGF-beta signaling pathwayhsa043506.413BMPR1B, GDF5, BMP2
Hippo signaling pathwayhsa043905.373BMPR1B, GDF5, BMP2
Cytokine-cytokine receptor interactionhsa040604.673BMPR1B, GDF5, BMP2
Signaling pathways regulating pluripotency of stem cellshsa045505.62BMPR1B, BMP2

NET-GE enrichment

Term New enriched termICP valueGenes
TGF-beta signaling pathway (hsa04350) -6.410.0BMPR1B, GDF5, BMP2
Signaling pathways regulating pluripotency of stem cells (hsa04550) -5.60.02BMPR1B, BMP2
Hippo signaling pathway (hsa04390) -5.370.0BMPR1B, GDF5, BMP2
Signaling molecules and interactionNEW3.090.026BMPR1B, GDF5, BMP2
Cytokine-cytokine receptor interaction (hsa04060) -4.670.001BMPR1B, GDF5, BMP2
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Elastic fibre formationR-HSA-15669487.492GDF5, BMP2
Extracellular matrix organizationR-HSA-14742444.912GDF5, BMP2
Molecules associated with elastic fibresR-HSA-21293797.732GDF5, BMP2
Signaling by BMPR-HSA-2014518.462BMPR1B, BMP2
Signal TransductionR-HSA-1625821.782BMPR1B, BMP2

NET-GE enrichment

Term New enriched termICP valueGenes
Elastic fibre formation (R-HSA-1566948) -7.490.001BMPR1B, GDF5, BMP2
Extracellular matrix organization (R-HSA-1474244) -4.910.02GDF5, BMP2
Molecules associated with elastic fibres (R-HSA-2129379) -7.730.0BMPR1B, GDF5, BMP2
Signaling by BMP (R-HSA-201451) -8.460.001BMPR1B, BMP2
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.183BMPR1B, GDF5, BMP2
protein binding (GO:0005515) 0.463BMPR1B, GDF5, BMP2
cytokine receptor binding (GO:0005126) 4.142GDF5, BMP2
cytokine activity (GO:0005125) 4.342GDF5, BMP2
growth factor activity (GO:0008083) 4.662GDF5, BMP2
transforming growth factor beta receptor binding (GO:0005160) 5.812GDF5, BMP2
SMAD binding (GO:0046332) 5.452BMPR1B, BMP2
catalytic activity (GO:0003824) 1.052BMPR1B, BMP2
receptor binding (GO:0005102) 2.432GDF5, BMP2

NET-GE enrichment

Term New enriched termICP valueGenes
cytokine activity (GO:0005125) -4.340.006BMPR1B, GDF5, BMP2
growth factor activity (GO:0008083) -4.660.015BMPR1B, GDF5, BMP2
SMAD binding (GO:0046332) -5.450.027BMPR1B, BMP2
receptor signaling protein serine/threonine kinase activity (GO:0004702) NEW5.230.029BMPR1B, BMP2
coreceptor activity (GO:0015026) NEW6.10.007BMPR1B, BMP2
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
developmental process (GO:0032502) 1.363BMPR1B, GDF5, BMP2
regulation of RNA metabolic process (GO:0051252) 1.523BMPR1B, GDF5, BMP2
positive regulation of metabolic process (GO:0009893) 1.743BMPR1B, GDF5, BMP2
regulation of metabolic process (GO:0019222) 1.023BMPR1B, GDF5, BMP2
regulation of cellular biosynthetic process (GO:0031326) 1.383BMPR1B, GDF5, BMP2
positive regulation of cellular metabolic process (GO:0031325) 1.813BMPR1B, GDF5, BMP2
positive regulation of response to stimulus (GO:0048584) 2.183BMPR1B, GDF5, BMP2
regulation of response to stimulus (GO:0048583) 1.543BMPR1B, GDF5, BMP2
positive regulation of signaling (GO:0023056) 2.413BMPR1B, GDF5, BMP2
signal transduction (GO:0007165) 1.283BMPR1B, GDF5, BMP2
cell surface receptor signaling pathway (GO:0007166) 2.093BMPR1B, GDF5, BMP2
enzyme linked receptor protein signaling pathway (GO:0007167) 3.243BMPR1B, GDF5, BMP2
positive regulation of cell communication (GO:0010647) 2.413BMPR1B, GDF5, BMP2
anatomical structure morphogenesis (GO:0009653) 2.533BMPR1B, GDF5, BMP2
regulation of apoptotic process (GO:0042981) 2.53BMPR1B, GDF5, BMP2
regulation of biological process (GO:0050789) 0.453BMPR1B, GDF5, BMP2
single-organism process (GO:0044699) 0.483BMPR1B, GDF5, BMP2
regulation of primary metabolic process (GO:0080090) 1.083BMPR1B, GDF5, BMP2
regulation of cell communication (GO:0010646) 1.733BMPR1B, GDF5, BMP2
positive regulation of macromolecule metabolic process (GO:0010604) 1.813BMPR1B, GDF5, BMP2
regulation of transcription from RNA polymerase II promoter (GO:0006357) 2.243BMPR1B, GDF5, BMP2
regulation of signal transduction (GO:0009966) 1.843BMPR1B, GDF5, BMP2
cellular developmental process (GO:0048869) 1.823BMPR1B, GDF5, BMP2
positive regulation of multicellular organismal process (GO:0051240) 2.493BMPR1B, GDF5, BMP2
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.463BMPR1B, GDF5, BMP2
regulation of signaling (GO:0023051) 1.723BMPR1B, GDF5, BMP2
regulation of developmental process (GO:0050793) 2.13BMPR1B, GDF5, BMP2
regulation of programmed cell death (GO:0043067) 2.493BMPR1B, GDF5, BMP2
animal organ development (GO:0048513) 2.533BMPR1B, GDF5, BMP2
biological regulation (GO:0065007) 0.393BMPR1B, GDF5, BMP2
chondrocyte differentiation (GO:0002062) 5.883BMPR1B, GDF5, BMP2
negative regulation of biological process (GO:0048519) 1.333BMPR1B, GDF5, BMP2
regulation of gene expression (GO:0010468) 1.373BMPR1B, GDF5, BMP2
regulation of cell proliferation (GO:0042127) 2.413BMPR1B, GDF5, BMP2
negative regulation of cell proliferation (GO:0008285) 3.263BMPR1B, GDF5, BMP2
cell differentiation (GO:0030154) 2.143BMPR1B, GDF5, BMP2
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.433BMPR1B, GDF5, BMP2
regulation of cellular metabolic process (GO:0031323) 1.073BMPR1B, GDF5, BMP2
cellular process (GO:0009987) 0.263BMPR1B, GDF5, BMP2
regulation of biosynthetic process (GO:0009889) 1.373BMPR1B, GDF5, BMP2
regulation of nucleic acid-templated transcription (GO:1903506) 1.553BMPR1B, GDF5, BMP2
regulation of cellular process (GO:0050794) 0.53BMPR1B, GDF5, BMP2
single-organism developmental process (GO:0044767) 1.493BMPR1B, GDF5, BMP2
positive regulation of biological process (GO:0048518) 1.23BMPR1B, GDF5, BMP2
regulation of cell differentiation (GO:0045595) 2.423BMPR1B, GDF5, BMP2
regulation of cartilage development (GO:0061035) 5.63BMPR1B, GDF5, BMP2
single-organism cellular process (GO:0044763) 0.653BMPR1B, GDF5, BMP2
regulation of nitrogen compound metabolic process (GO:0051171) 1.363BMPR1B, GDF5, BMP2
regulation of multicellular organismal process (GO:0051239) 1.873BMPR1B, GDF5, BMP2
regulation of RNA biosynthetic process (GO:2001141) 1.553BMPR1B, GDF5, BMP2
growth (GO:0040007) 3.83BMPR1B, GDF5, BMP2
transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178) 4.63BMPR1B, GDF5, BMP2
positive regulation of cell differentiation (GO:0045597) 3.013BMPR1B, GDF5, BMP2
positive regulation of cartilage development (GO:0061036) 6.363BMPR1B, GDF5, BMP2
cartilage development (GO:0051216) 5.313BMPR1B, GDF5, BMP2
positive regulation of developmental process (GO:0051094) 2.773BMPR1B, GDF5, BMP2
regulation of macromolecule metabolic process (GO:0060255) 1.083BMPR1B, GDF5, BMP2
anatomical structure development (GO:0048856) 1.583BMPR1B, GDF5, BMP2
regulation of cell death (GO:0010941) 2.433BMPR1B, GDF5, BMP2
regulation of transcription, DNA-templated (GO:0006355) 1.563BMPR1B, GDF5, BMP2
regulation of macromolecule biosynthetic process (GO:0010556) 1.433BMPR1B, GDF5, BMP2
regulation of multicellular organismal development (GO:2000026) 2.313BMPR1B, GDF5, BMP2
positive regulation of signal transduction (GO:0009967) 2.53BMPR1B, GDF5, BMP2
negative regulation of cellular process (GO:0048523) 1.413BMPR1B, GDF5, BMP2
positive regulation of cellular process (GO:0048522) 1.33BMPR1B, GDF5, BMP2
limb morphogenesis (GO:0035108) 5.052BMPR1B, GDF5
regulation of phosphate metabolic process (GO:0019220) 2.352GDF5, BMP2
appendage morphogenesis (GO:0035107) 5.052BMPR1B, GDF5
skeletal system development (GO:0001501) 4.492BMPR1B, BMP2
regulation of bone mineralization (GO:0030500) 5.492BMPR1B, BMP2
positive regulation of bone mineralization (GO:0030501) 6.152BMPR1B, BMP2
cellular component organization or biogenesis (GO:0071840) 1.222GDF5, BMP2
single-organism metabolic process (GO:0044710) 1.632BMPR1B, BMP2
response to growth factor (GO:0070848) 4.142BMPR1B, BMP2
regulation of neuron differentiation (GO:0045664) 3.392GDF5, BMP2
regulation of osteoblast differentiation (GO:0045667) 4.992BMPR1B, BMP2
positive regulation of neuron differentiation (GO:0045666) 3.982GDF5, BMP2
positive regulation of cell development (GO:0010720) 3.572GDF5, BMP2
positive regulation of osteoblast differentiation (GO:0045669) 5.622BMPR1B, BMP2
cell development (GO:0048468) 3.282BMPR1B, GDF5
regionalization (GO:0003002) 4.242BMPR1B, BMP2
cellular response to growth factor stimulus (GO:0071363) 4.272BMPR1B, BMP2
response to organic substance (GO:0010033) 2.22BMPR1B, BMP2
regulation of phosphorylation (GO:0042325) 2.52GDF5, BMP2
single organism signaling (GO:0044700) 3.252GDF5, BMP2
positive regulation of phosphorylation (GO:0042327) 2.92GDF5, BMP2
single-multicellular organism process (GO:0044707) 1.782BMPR1B, BMP2
BMP signaling pathway (GO:0030509) 5.332BMPR1B, BMP2
protein metabolic process (GO:0019538) 1.452BMPR1B, BMP2
SMAD protein signal transduction (GO:0060395) 5.652GDF5, BMP2
regulation of pathway-restricted SMAD protein phosphorylation (GO:0060393) 5.632GDF5, BMP2
positive regulation of biosynthetic process (GO:0009891) 2.292BMPR1B, BMP2
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) 4.392GDF5, BMP2
positive regulation of gene expression (GO:0010628) 2.352BMPR1B, BMP2
positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862) 5.862GDF5, BMP2
cellular protein metabolic process (GO:0044267) 1.632BMPR1B, BMP2
cellular macromolecule metabolic process (GO:0044260) 0.932BMPR1B, BMP2
cellular component organization (GO:0016043) 1.242GDF5, BMP2
organ morphogenesis (GO:0009887) 3.552BMPR1B, BMP2
positive regulation of biomineral tissue development (GO:0070169) 6.072BMPR1B, BMP2
cellular response to stimulus (GO:0051716) 1.972BMPR1B, BMP2
regulation of biomineral tissue development (GO:0070167) 5.412BMPR1B, BMP2
defense response (GO:0006952) 2.782BMPR1B, BMP2
macromolecule modification (GO:0043412) 1.732BMPR1B, BMP2
protein modification process (GO:0036211) 1.792BMPR1B, BMP2
inflammatory response (GO:0006954) 3.642BMPR1B, BMP2
regulation of ossification (GO:0030278) 4.532BMPR1B, BMP2
regulation of intracellular signal transduction (GO:1902531) 2.312GDF5, BMP2
response to stimulus (GO:0050896) 1.222BMPR1B, BMP2
positive regulation of protein modification process (GO:0031401) 2.72GDF5, BMP2
response to stress (GO:0006950) 1.82BMPR1B, BMP2
positive regulation of nervous system development (GO:0051962) 3.642GDF5, BMP2
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.392BMPR1B, BMP2
regulation of nervous system development (GO:0051960) 3.12GDF5, BMP2
response to BMP (GO:0071772) 6.172BMPR1B, BMP2
cellular response to BMP stimulus (GO:0071773) 6.172BMPR1B, BMP2
metabolic process (GO:0008152) 0.582BMPR1B, BMP2
phosphorylation (GO:0016310) 2.632BMPR1B, BMP2
signaling (GO:0023052) 3.252GDF5, BMP2
cellular response to chemical stimulus (GO:0070887) 2.572BMPR1B, BMP2
cell communication (GO:0007154) 3.042GDF5, BMP2
regulation of MAPK cascade (GO:0043408) 3.222GDF5, BMP2
response to endogenous stimulus (GO:0009719) 2.792BMPR1B, BMP2
regulation of neurogenesis (GO:0050767) 3.212GDF5, BMP2
regulation of chondrocyte differentiation (GO:0032330) 5.922BMPR1B, GDF5
positive regulation of phosphorus metabolic process (GO:0010562) 2.782GDF5, BMP2
negative regulation of multicellular organismal process (GO:0051241) 2.842GDF5, BMP2
regulation of protein metabolic process (GO:0051246) 1.932GDF5, BMP2
positive regulation of protein metabolic process (GO:0051247) 2.432GDF5, BMP2
regulation of cell development (GO:0060284) 3.012GDF5, BMP2
positive regulation of neurogenesis (GO:0050769) 3.772GDF5, BMP2
positive regulation of chondrocyte differentiation (GO:0032332) 6.782BMPR1B, GDF5
positive regulation of cellular protein metabolic process (GO:0032270) 2.492GDF5, BMP2
regulation of protein modification process (GO:0031399) 2.322GDF5, BMP2
cellular response to endogenous stimulus (GO:0071495) 3.332BMPR1B, BMP2
multicellular organismal process (GO:0032501) 1.452BMPR1B, BMP2
negative regulation of cell differentiation (GO:0045596) 3.332GDF5, BMP2
positive regulation of transcription, DNA-templated (GO:0045893) 2.562BMPR1B, BMP2
negative regulation of developmental process (GO:0051093) 3.172GDF5, BMP2
regulation of cellular protein metabolic process (GO:0032268) 1.992GDF5, BMP2
regulation of epithelial cell proliferation (GO:0050678) 4.062GDF5, BMP2
carbohydrate derivative metabolic process (GO:1901135) 3.072BMPR1B, BMP2
positive regulation of RNA metabolic process (GO:0051254) 2.512BMPR1B, BMP2
macromolecule metabolic process (GO:0043170) 0.832BMPR1B, BMP2
positive regulation of RNA biosynthetic process (GO:1902680) 2.542BMPR1B, BMP2
positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 2.812BMPR1B, BMP2
system development (GO:0048731) 2.922BMPR1B, BMP2
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.562BMPR1B, BMP2
positive regulation of cellular biosynthetic process (GO:0031328) 2.32BMPR1B, BMP2
positive regulation of cell death (GO:0010942) 3.322BMPR1B, BMP2
glycoprotein metabolic process (GO:0009100) 5.232BMPR1B, BMP2
pattern specification process (GO:0007389) 3.792BMPR1B, BMP2
positive regulation of apoptotic process (GO:0043065) 3.382BMPR1B, BMP2
organic substance metabolic process (GO:0071704) 0.632BMPR1B, BMP2
cellular response to organic substance (GO:0071310) 2.782BMPR1B, BMP2
proteoglycan metabolic process (GO:0006029) 5.782BMPR1B, BMP2
positive regulation of programmed cell death (GO:0043068) 3.382BMPR1B, BMP2
protein phosphorylation (GO:0006468) 2.892BMPR1B, BMP2
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.352BMPR1B, BMP2
positive regulation of phosphate metabolic process (GO:0045937) 2.782GDF5, BMP2
cellular protein modification process (GO:0006464) 1.792BMPR1B, BMP2
regulation of phosphorus metabolic process (GO:0051174) 2.352GDF5, BMP2
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.292BMPR1B, BMP2
cell-cell signaling (GO:0007267) 3.352GDF5, BMP2
response to chemical (GO:0042221) 1.982BMPR1B, BMP2
primary metabolic process (GO:0044238) 0.692BMPR1B, BMP2
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100) 5.122GDF5, BMP2
positive regulation of ossification (GO:0045778) 5.272BMPR1B, BMP2
cellular metabolic process (GO:0044237) 0.692BMPR1B, BMP2
phosphate-containing compound metabolic process (GO:0006796) 2.162BMPR1B, BMP2
phosphorus metabolic process (GO:0006793) 2.152BMPR1B, BMP2
regulation of protein phosphorylation (GO:0001932) 2.572GDF5, BMP2
positive regulation of protein phosphorylation (GO:0001934) 2.952GDF5, BMP2

NET-GE enrichment

Term New enriched termICP valueGenes
limb morphogenesis (GO:0035108) -5.050.036BMPR1B, GDF5, BMP2
regulation of mesenchymal cell apoptotic process (GO:2001053) NEW7.240.01BMPR1B, GDF5
appendage morphogenesis (GO:0035107) -5.050.036BMPR1B, GDF5, BMP2
BMP signaling pathway (GO:0030509) -5.330.018BMPR1B, BMP2
cartilage condensation (GO:0001502) NEW6.640.028BMPR1B, BMP2
ossification (GO:0001503) NEW4.860.014BMPR1B, GDF5, BMP2
enzyme linked receptor protein signaling pathway (GO:0007167) -3.240.03BMPR1B, GDF5, BMP2
regulation of bone mineralization (GO:0030500) -5.490.017BMPR1B, BMP2
positive regulation of bone mineralization (GO:0030501) -6.150.005BMPR1B, BMP2
negative regulation of mesenchymal cell apoptotic process (GO:2001054) NEW7.430.004BMPR1B, GDF5
pathway-restricted SMAD protein phosphorylation (GO:0060389) NEW7.160.004BMPR1B, BMP2
regulation of osteoblast differentiation (GO:0045667) -4.990.044BMPR1B, GDF5, BMP2
positive regulation of neuron differentiation (GO:0045666) -3.980.004BMPR1B, GDF5, BMP2
chondrocyte differentiation (GO:0002062) -5.880.0BMPR1B, GDF5, BMP2
positive regulation of osteoblast differentiation (GO:0045669) -5.620.001BMPR1B, GDF5, BMP2
mesenchymal cell differentiation (GO:0048762) NEW6.510.029BMPR1B, BMP2
positive regulation of biomineral tissue development (GO:0070169) -6.070.005BMPR1B, BMP2
skeletal system development (GO:0001501) -4.490.04BMPR1B, GDF5, BMP2
atrial cardiac muscle tissue morphogenesis (GO:0055009) NEW8.120.003BMPR1B, BMP2
regulation of biomineral tissue development (GO:0070167) -5.410.02BMPR1B, BMP2
positive regulation of cell differentiation (GO:0045597) -3.010.015BMPR1B, GDF5, BMP2
regulation of cartilage development (GO:0061035) -5.60.001BMPR1B, GDF5, BMP2
regulation of ossification (GO:0030278) -4.530.038BMPR1B, GDF5, BMP2
transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0007178) -4.60.001BMPR1B, GDF5, BMP2
cartilage development (GO:0051216) -5.310.003BMPR1B, GDF5, BMP2
positive regulation of developmental process (GO:0051094) -2.770.04BMPR1B, GDF5, BMP2
positive regulation of ossification (GO:0045778) -5.270.008BMPR1B, BMP2
positive regulation of epithelial to mesenchymal transition (GO:0010718) NEW6.230.034BMPR1B, BMP2
regulation of canonical Wnt signaling pathway (GO:0060828) NEW4.260.024BMPR1B, GDF5, BMP2
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cell part (GO:0044464) 0.113BMPR1B, GDF5, BMP2
protein complex (GO:0043234) 1.512BMPR1B, BMP2
receptor complex (GO:0043235) 4.012BMPR1B, BMP2
macromolecular complex (GO:0032991) 1.352BMPR1B, BMP2
extracellular space (GO:0005615) 2.632GDF5, BMP2
membrane (GO:0016020) 0.682BMPR1B, GDF5
plasma membrane receptor complex (GO:0098802) 4.632BMPR1B, BMP2
plasma membrane protein complex (GO:0098797) 3.552BMPR1B, BMP2
membrane protein complex (GO:0098796) 2.842BMPR1B, BMP2
extracellular region (GO:0005576) 2.182GDF5, BMP2
plasma membrane (GO:0005886) 1.392BMPR1B, GDF5
membrane part (GO:0044425) 0.952BMPR1B, BMP2
plasma membrane part (GO:0044459) 1.952BMPR1B, BMP2
extracellular region part (GO:0044421) 1.572GDF5, BMP2

NET-GE enrichment

Term New enriched termICP valueGenes
endoplasmic reticulum-Golgi intermediate compartment (GO:0005793) NEW5.630.011BMPR1B, BMP2