Disease table of EPILEPSY, PROGRESSIVE MYOCLONIC OMIM ID: PS254800

Gene-disease associations table

GeneAssociated with EPILEPSY, PROGRESSIVE MYOCLONIC inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
LMNB2ClinVar, OMIM, HUMSAVARHGNC link19p13.32608709, PS254800
PRICKLE1ClinVar, OMIM, HUMSAVARHGNC link12q121PS254800
EPM2AClinVar, OMIM, HUMSAVARHGNC link6q24.31PS254800
KCTD7ClinVar, OMIM, HUMSAVARHGNC link7q11.211PS254800
KCNC1ClinVar, OMIM, HUMSAVARHGNC link11p15.11PS254800
CERS1ClinVar, OMIM, HUMSAVARHGNC link19p13.111PS254800
CSTBClinVar, OMIM, HUMSAVARHGNC link21q22.31PS254800
SCARB2ClinVar, OMIM, HUMSAVARHGNC link4q21.11PS254800
NHLRC1ClinVar, OMIM, HUMSAVARHGNC link6p22.31PS254800
TBC1D24ClinVarHGNC link16p13.36PS220290, 605021, PS124900, PS308350, PS254800, 220500
GOSR2ClinVar, OMIM, HUMSAVARHGNC link17q21.321PS254800
PRDM8ClinVar, OMIM, HUMSAVARHGNC link4q21.211PS254800

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
By band
Shared bandNumber of genes associated with the diseaseGenes associated with the disease
19p132LMNB2, CERS1
4q212SCARB2, PRDM8
By region
Shared regionNumber of genes associated with the diseaseGenes associated with the disease
4q22SCARB2, PRDM8
19p12LMNB2, CERS1
By arm
Shared armNumber of genes associated with the diseaseGenes associated with the disease
19p2LMNB2, CERS1
4q2SCARB2, PRDM8
By chromosome
Shared chromosomeNumber of genes associated with the diseaseGenes associated with the disease
192LMNB2, CERS1
42SCARB2, PRDM8
62EPM2A, NHLRC1
Transcription Factors (TF) annotation from TRRUST
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
SCARB2YES2STAT2, SPI10
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
LMNB2CSTBNo1ABCE1
LMNB2SCARB2No1NTRK1
EPM2ANHLRC1Yes5NHLRC1, EPM2A, UBE2N, PPP1R3C, STUB1
EPM2APRDM8No1NHLRC1
KCTD7CSTBNo1CUL3
KCTD7TBC1D24No1CUL3
CERS1GOSR2No1TCTN3
CSTBTBC1D24No1CUL3
CSTBPRDM8No1MCM2
NHLRC1PRDM8Yes1NHLRC1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
LMNB2PRICKLE1No-1UBC
LMNB2EPM2ANo-1UBC
LMNB2KCTD7No-1UBC
LMNB2CERS1No-1UBC
LMNB2CSTBNo-1UBC
LMNB2NHLRC1No-1UBC
PRICKLE1EPM2ANo-4UBC, UBA52, RPS27A, UBB
PRICKLE1KCTD7No-2UBC, UBB
PRICKLE1CERS1No-1UBC
PRICKLE1CSTBNo-1UBC
PRICKLE1NHLRC1No-5UBC, UBA52, UBB, RPS27A, DVL2
EPM2AKCTD7No-2UBC, UBB
EPM2ACERS1No-1UBC
EPM2ACSTBNo-1UBC
EPM2ANHLRC1Yesbinding9RPS27A, GYS2, PPP1R3C, GYG2, GYG1, UBC, UBB, UBA52, GYS1
EPM2APRDM8No-1NHLRC1
KCTD7CERS1No-1UBC
KCTD7CSTBNo-1UBC
KCTD7NHLRC1No-2UBC, UBB
CERS1CSTBNo-1UBC
CERS1NHLRC1No-1UBC
CSTBNHLRC1No-1UBC
NHLRC1PRDM8Yesbinding0

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
MetabolismR-HSA-14307282.343NHLRC1, CERS1, EPM2A
Glycogen storage diseasesR-HSA-32291219.522EPM2A, NHLRC1
Glucose metabolismR-HSA-703266.772NHLRC1, EPM2A
Myoclonic epilepsy of LaforaR-HSA-37856539.522NHLRC1, EPM2A
Diseases of carbohydrate metabolismR-HSA-56630848.282EPM2A, NHLRC1
Diseases of metabolismR-HSA-56689146.572NHLRC1, EPM2A
Glycogen synthesisR-HSA-33220779.082EPM2A, NHLRC1
DiseaseR-HSA-16436853.332EPM2A, NHLRC1
Metabolism of carbohydratesR-HSA-713874.932NHLRC1, EPM2A

NET-GE enrichment

Term New enriched termICP valueGenes
Glycogen storage diseases (R-HSA-3229121) -9.520.001EPM2A, NHLRC1
Glucose metabolism (R-HSA-70326) -6.770.03NHLRC1, EPM2A
Myoclonic epilepsy of Lafora (R-HSA-3785653) -9.520.001NHLRC1, EPM2A
Diseases of carbohydrate metabolism (R-HSA-5663084) -8.280.004EPM2A, NHLRC1
Diseases of metabolism (R-HSA-5668914) -6.570.04NHLRC1, EPM2A
Glycogen synthesis (R-HSA-3322077) -9.080.001EPM2A, NHLRC1
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.1811PRICKLE1, GOSR2, TBC1D24, KCTD7, EPM2A, CSTB, PRDM8, KCNC1, SCARB2, NHLRC1, CERS1
protein binding (GO:0005515) 0.4610PRICKLE1, GOSR2, TBC1D24, EPM2A, CSTB, PRDM8, KCNC1, SCARB2, NHLRC1, CERS1
cation binding (GO:0043169) 1.44KCTD7, PRDM8, PRICKLE1, NHLRC1
catalytic activity (GO:0003824) 1.054CERS1, NHLRC1, EPM2A, PRDM8
metal ion binding (GO:0046872) 1.414KCTD7, PRDM8, PRICKLE1, NHLRC1
ion binding (GO:0043167) 1.364PRDM8, KCTD7, PRICKLE1, NHLRC1
transition metal ion binding (GO:0046914) 2.483KCTD7, PRICKLE1, NHLRC1
organic cyclic compound binding (GO:0097159) 1.053KCTD7, PRDM8, CSTB
transferase activity (GO:0016740) 1.953NHLRC1, CERS1, PRDM8
zinc ion binding (GO:0008270) 2.663KCTD7, PRICKLE1, NHLRC1
nucleic acid binding (GO:0003676) 1.443KCTD7, PRDM8, CSTB
heterocyclic compound binding (GO:1901363) 1.063PRDM8, KCTD7, CSTB
transporter activity (GO:0005215) 2.572KCNC1, GOSR2
enzyme regulator activity (GO:0030234) 2.852TBC1D24, CSTB
molecular function regulator (GO:0098772) 2.512TBC1D24, CSTB
enzyme binding (GO:0019899) 2.272SCARB2, CSTB
DNA binding (GO:0003677) 1.922PRDM8, KCTD7
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.269NHLRC1, GOSR2, TBC1D24, KCTD7, EPM2A, PRDM8, KCNC1, SCARB2, CERS1
biological regulation (GO:0065007) 0.399PRDM8, NHLRC1, GOSR2, TBC1D24, PRICKLE1, CSTB, EPM2A, KCNC1, CERS1
regulation of biological process (GO:0050789) 0.459PRDM8, NHLRC1, GOSR2, TBC1D24, PRICKLE1, CSTB, EPM2A, KCNC1, CERS1
single-organism process (GO:0044699) 0.489PRDM8, NHLRC1, GOSR2, TBC1D24, PRICKLE1, CSTB, EPM2A, KCNC1, CERS1
regulation of cellular process (GO:0050794) 0.59PRICKLE1, GOSR2, TBC1D24, EPM2A, CSTB, PRDM8, KCNC1, NHLRC1, CERS1
single-organism cellular process (GO:0044763) 0.657EPM2A, GOSR2, TBC1D24, NHLRC1, PRDM8, KCNC1, CERS1
regulation of macromolecule metabolic process (GO:0060255) 1.085PRDM8, PRICKLE1, CERS1, NHLRC1, CSTB
regulation of cellular metabolic process (GO:0031323) 1.075PRDM8, PRICKLE1, CERS1, NHLRC1, CSTB
regulation of primary metabolic process (GO:0080090) 1.085PRDM8, PRICKLE1, CERS1, NHLRC1, CSTB
regulation of metabolic process (GO:0019222) 1.025PRDM8, PRICKLE1, CERS1, NHLRC1, CSTB
developmental process (GO:0032502) 1.364PRDM8, PRICKLE1, KCNC1, EPM2A
primary metabolic process (GO:0044238) 0.694CERS1, NHLRC1, EPM2A, PRDM8
transport (GO:0006810) 1.514PRICKLE1, KCNC1, SCARB2, GOSR2
organic substance metabolic process (GO:0071704) 0.634NHLRC1, EPM2A, CERS1, PRDM8
cellular component organization (GO:0016043) 1.244TBC1D24, KCTD7, KCNC1, GOSR2
anatomical structure development (GO:0048856) 1.584PRDM8, PRICKLE1, KCNC1, EPM2A
cellular metabolic process (GO:0044237) 0.694NHLRC1, EPM2A, CERS1, PRDM8
cellular biosynthetic process (GO:0044249) 1.374CERS1, NHLRC1, EPM2A, PRDM8
biosynthetic process (GO:0009058) 1.324NHLRC1, EPM2A, CERS1, PRDM8
cellular component organization or biogenesis (GO:0071840) 1.224TBC1D24, KCTD7, KCNC1, GOSR2
metabolic process (GO:0008152) 0.584CERS1, NHLRC1, EPM2A, PRDM8
organic substance biosynthetic process (GO:1901576) 1.344CERS1, NHLRC1, EPM2A, PRDM8
positive regulation of biological process (GO:0048518) 1.24KCNC1, PRICKLE1, EPM2A, NHLRC1
negative regulation of biological process (GO:0048519) 1.334PRICKLE1, CERS1, EPM2A, CSTB
establishment of localization (GO:0051234) 1.484PRICKLE1, KCNC1, SCARB2, GOSR2
localization (GO:0051179) 1.44PRICKLE1, KCNC1, SCARB2, GOSR2
negative regulation of cellular process (GO:0048523) 1.414PRICKLE1, CERS1, EPM2A, CSTB
positive regulation of cellular process (GO:0048522) 1.34NHLRC1, EPM2A, KCNC1, PRICKLE1
protein localization (GO:0008104) 2.363PRICKLE1, SCARB2, GOSR2
negative regulation of metabolic process (GO:0009892) 1.933PRICKLE1, CERS1, CSTB
macromolecular complex subunit organization (GO:0043933) 2.143KCTD7, KCNC1, GOSR2
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.463PRICKLE1, CERS1, PRDM8
negative regulation of cellular metabolic process (GO:0031324) 2.013PRICKLE1, CERS1, CSTB
regulation of cellular biosynthetic process (GO:0031326) 1.383PRICKLE1, CERS1, PRDM8
cellular component assembly (GO:0022607) 2.143KCTD7, KCNC1, GOSR2
cellular macromolecule biosynthetic process (GO:0034645) 1.663NHLRC1, EPM2A, PRDM8
cellular response to stimulus (GO:0051716) 1.973CERS1, KCNC1, GOSR2
single-organism biosynthetic process (GO:0044711) 2.83NHLRC1, CERS1, EPM2A
negative regulation of macromolecule metabolic process (GO:0010605) 2.013PRICKLE1, CERS1, CSTB
cellular macromolecule metabolic process (GO:0044260) 0.933NHLRC1, EPM2A, PRDM8
cellular macromolecule localization (GO:0070727) 3.13PRICKLE1, SCARB2, GOSR2
intracellular protein transport (GO:0006886) 3.23PRICKLE1, SCARB2, GOSR2
regulation of protein metabolic process (GO:0051246) 1.933PRICKLE1, NHLRC1, CSTB
macromolecular complex assembly (GO:0065003) 2.553KCTD7, KCNC1, GOSR2
organic substance transport (GO:0071702) 2.153PRICKLE1, SCARB2, GOSR2
regulation of molecular function (GO:0065009) 1.783TBC1D24, CERS1, CSTB
macromolecule localization (GO:0033036) 2.343PRICKLE1, SCARB2, GOSR2
cellular protein localization (GO:0034613) 3.113PRICKLE1, SCARB2, GOSR2
regulation of catalytic activity (GO:0050790) 1.973CERS1, TBC1D24, CSTB
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.433PRICKLE1, CERS1, PRDM8
establishment of protein localization to organelle (GO:0072594) 3.923PRICKLE1, SCARB2, GOSR2
protein complex assembly (GO:0006461) 2.783KCTD7, KCNC1, GOSR2
regulation of biosynthetic process (GO:0009889) 1.373PRICKLE1, CERS1, PRDM8
single-organism metabolic process (GO:0044710) 1.633EPM2A, CERS1, NHLRC1
establishment of protein localization (GO:0045184) 2.533PRICKLE1, SCARB2, GOSR2
protein transport (GO:0015031) 2.623PRICKLE1, SCARB2, GOSR2
macromolecule biosynthetic process (GO:0009059) 1.613NHLRC1, EPM2A, PRDM8
regulation of nitrogen compound metabolic process (GO:0051171) 1.363PRICKLE1, CERS1, PRDM8
establishment of localization in cell (GO:0051649) 2.473PRICKLE1, SCARB2, GOSR2
cellular localization (GO:0051641) 2.323PRICKLE1, SCARB2, GOSR2
single-organism developmental process (GO:0044767) 1.493PRICKLE1, KCNC1, PRDM8
regulation of cellular protein metabolic process (GO:0032268) 1.993PRICKLE1, NHLRC1, CSTB
protein complex subunit organization (GO:0071822) 2.63KCTD7, KCNC1, GOSR2
intracellular transport (GO:0046907) 2.673PRICKLE1, SCARB2, GOSR2
response to stimulus (GO:0050896) 1.223CERS1, KCNC1, GOSR2
macromolecule metabolic process (GO:0043170) 0.833NHLRC1, EPM2A, PRDM8
regulation of macromolecule biosynthetic process (GO:0010556) 1.433PRICKLE1, CERS1, PRDM8
protein localization to organelle (GO:0033365) 3.573PRICKLE1, SCARB2, GOSR2
response to toxic substance (GO:0009636) 4.882CERS1, KCNC1
negative regulation of response to stimulus (GO:0048585) 2.522PRICKLE1, EPM2A
regulation of response to stimulus (GO:0048583) 1.542PRICKLE1, EPM2A
behavior (GO:0007610) 3.472EPM2A, CSTB
signal transduction (GO:0007165) 1.282PRICKLE1, GOSR2
positive regulation of macromolecule metabolic process (GO:0010604) 1.812PRICKLE1, NHLRC1
negative regulation of signal transduction (GO:0009968) 2.752PRICKLE1, EPM2A
regulation of signal transduction (GO:0009966) 1.842PRICKLE1, EPM2A
cellular glucan metabolic process (GO:0006073) 5.652EPM2A, NHLRC1
negative regulation of molecular function (GO:0044092) 2.742CERS1, CSTB
protein targeting (GO:0006605) 4.082SCARB2, GOSR2
regulation of proteolysis (GO:0030162) 3.22PRICKLE1, CSTB
regulation of RNA biosynthetic process (GO:2001141) 1.552PRICKLE1, PRDM8
response to organic substance (GO:0010033) 2.22CERS1, KCNC1
oxidation-reduction process (GO:0055114) 2.912NHLRC1, EPM2A
single-multicellular organism process (GO:0044707) 1.782EPM2A, CSTB
protein metabolic process (GO:0019538) 1.452NHLRC1, EPM2A
single-organism behavior (GO:0044708) 3.792EPM2A, CSTB
carbohydrate biosynthetic process (GO:0016051) 4.932EPM2A, NHLRC1
glucan biosynthetic process (GO:0009250) 6.432NHLRC1, EPM2A
positive regulation of metabolic process (GO:0009893) 1.742PRICKLE1, NHLRC1
negative regulation of biosynthetic process (GO:0009890) 2.472PRICKLE1, CERS1
regulation of anatomical structure morphogenesis (GO:0022603) 2.792PRICKLE1, TBC1D24
nitrogen compound metabolic process (GO:0006807) 1.132PRDM8, CERS1
cellular protein metabolic process (GO:0044267) 1.632NHLRC1, EPM2A
cellular polysaccharide metabolic process (GO:0044264) 5.412NHLRC1, EPM2A
cellular carbohydrate metabolic process (GO:0044262) 4.742EPM2A, NHLRC1
energy reserve metabolic process (GO:0006112) 5.442NHLRC1, EPM2A
regulation of developmental process (GO:0050793) 2.12PRICKLE1, TBC1D24
protein targeting to vacuole (GO:0006623) 6.362SCARB2, GOSR2
macromolecule modification (GO:0043412) 1.732NHLRC1, EPM2A
protein modification process (GO:0036211) 1.792NHLRC1, EPM2A
single-organism carbohydrate metabolic process (GO:0044723) 3.422NHLRC1, EPM2A
regulation of hydrolase activity (GO:0051336) 2.532TBC1D24, CSTB
cellular nitrogen compound biosynthetic process (GO:0044271) 1.592PRDM8, CERS1
energy derivation by oxidation of organic compounds (GO:0015980) 4.932NHLRC1, EPM2A
positive regulation of protein modification process (GO:0031401) 2.72PRICKLE1, NHLRC1
regulation of transcription, DNA-templated (GO:0006355) 1.562PRICKLE1, PRDM8
negative regulation of macromolecule biosynthetic process (GO:0010558) 2.532PRICKLE1, CERS1
response to radiation (GO:0009314) 3.692CERS1, KCNC1
establishment of protein localization to vacuole (GO:0072666) 6.332SCARB2, GOSR2
protein localization to vacuole (GO:0072665) 5.972SCARB2, GOSR2
negative regulation of signaling (GO:0023057) 2.652PRICKLE1, EPM2A
cellular nitrogen compound metabolic process (GO:0034641) 1.222PRDM8, CERS1
response to light stimulus (GO:0009416) 4.082CERS1, KCNC1
negative regulation of cell communication (GO:0010648) 2.662PRICKLE1, EPM2A
cellular response to chemical stimulus (GO:0070887) 2.572CERS1, KCNC1
regulation of signaling (GO:0023051) 1.722PRICKLE1, EPM2A
regulation of cell communication (GO:0010646) 1.732PRICKLE1, EPM2A
negative regulation of catalytic activity (GO:0043086) 3.02CERS1, CSTB
positive regulation of protein metabolic process (GO:0051247) 2.432PRICKLE1, NHLRC1
regulation of protein modification by small protein conjugation or removal (GO:1903320) 4.142PRICKLE1, NHLRC1
positive regulation of protein modification by small protein conjugation or removal (GO:1903322) 4.482PRICKLE1, NHLRC1
positive regulation of cellular protein metabolic process (GO:0032270) 2.492PRICKLE1, NHLRC1
positive regulation of protein ubiquitination (GO:0031398) 4.552PRICKLE1, NHLRC1
regulation of protein modification process (GO:0031399) 2.322PRICKLE1, NHLRC1
regulation of protein ubiquitination (GO:0031396) 4.222PRICKLE1, NHLRC1
glucan metabolic process (GO:0044042) 5.652EPM2A, NHLRC1
multicellular organismal process (GO:0032501) 1.452EPM2A, CSTB
regulation of nucleic acid-templated transcription (GO:1903506) 1.552PRICKLE1, PRDM8
cellular carbohydrate biosynthetic process (GO:0034637) 5.762EPM2A, NHLRC1
protein oligomerization (GO:0051259) 3.712KCTD7, KCNC1
nervous system development (GO:0007399) 3.532EPM2A, PRDM8
vacuolar transport (GO:0007034) 4.182SCARB2, GOSR2
regulation of RNA metabolic process (GO:0051252) 1.522PRICKLE1, PRDM8
response to drug (GO:0042493) 3.712CERS1, KCNC1
cellular polysaccharide biosynthetic process (GO:0033692) 6.022NHLRC1, EPM2A
system development (GO:0048731) 2.922EPM2A, PRDM8
negative regulation of cellular biosynthetic process (GO:0031327) 2.492PRICKLE1, CERS1
positive regulation of cellular metabolic process (GO:0031325) 1.812PRICKLE1, NHLRC1
cellular response to drug (GO:0035690) 5.482CERS1, KCNC1
generation of precursor metabolites and energy (GO:0006091) 4.072NHLRC1, EPM2A
protein homooligomerization (GO:0051260) 4.212KCTD7, KCNC1
negative regulation of cellular macromolecule biosynthetic process (GO:2000113) 2.62PRICKLE1, CERS1
regulation of gene expression (GO:0010468) 1.372PRICKLE1, PRDM8
negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 2.552PRICKLE1, CERS1
autophagy (GO:0006914) 3.822EPM2A, NHLRC1
polysaccharide biosynthetic process (GO:0000271) 5.942EPM2A, NHLRC1
cellular protein modification process (GO:0006464) 1.792EPM2A, NHLRC1
single-organism transport (GO:0044765) 2.182PRICKLE1, KCNC1
negative regulation of nitrogen compound metabolic process (GO:0051172) 2.472PRICKLE1, CERS1
response to chemical (GO:0042221) 1.982CERS1, KCNC1
single-organism localization (GO:1902578) 2.092PRICKLE1, KCNC1
response to abiotic stimulus (GO:0009628) 2.82CERS1, KCNC1
carbohydrate metabolic process (GO:0005975) 3.262EPM2A, NHLRC1
glycogen metabolic process (GO:0005977) 5.672NHLRC1, EPM2A
polysaccharide metabolic process (GO:0005976) 5.322EPM2A, NHLRC1
glycogen biosynthetic process (GO:0005978) 6.432EPM2A, NHLRC1
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cell part (GO:0044464) 0.1112EPM2A, GOSR2, TBC1D24, KCTD7, PRICKLE1, CSTB, PRDM8, KCNC1, SCARB2, NHLRC1, CERS1, LMNB2
intracellular part (GO:0044424) 0.2811PRDM8, NHLRC1, GOSR2, TBC1D24, LMNB2, PRICKLE1, CSTB, EPM2A, SCARB2, CERS1, KCTD7
intracellular organelle (GO:0043229) 0.519PRDM8, NHLRC1, GOSR2, LMNB2, PRICKLE1, CSTB, EPM2A, SCARB2, CERS1
membrane-bounded organelle (GO:0043227) 0.479EPM2A, GOSR2, LMNB2, PRICKLE1, CSTB, PRDM8, SCARB2, NHLRC1, CERS1
intracellular membrane-bounded organelle (GO:0043231) 0.69EPM2A, GOSR2, LMNB2, PRICKLE1, CSTB, PRDM8, SCARB2, NHLRC1, CERS1
organelle (GO:0043226) 0.49EPM2A, GOSR2, LMNB2, PRICKLE1, CSTB, PRDM8, SCARB2, NHLRC1, CERS1
membrane (GO:0016020) 0.688EPM2A, GOSR2, KCTD7, PRICKLE1, KCNC1, SCARB2, CERS1, LMNB2
cytoplasmic part (GO:0044444) 0.827PRICKLE1, GOSR2, KCTD7, EPM2A, SCARB2, NHLRC1, CERS1
intracellular organelle part (GO:0044446) 0.816PRICKLE1, GOSR2, LMNB2, CSTB, SCARB2, CERS1
nucleus (GO:0005634) 1.076NHLRC1, LMNB2, EPM2A, CSTB, PRDM8, PRICKLE1
organelle part (GO:0044422) 0.796PRICKLE1, GOSR2, LMNB2, CSTB, SCARB2, CERS1
cytoplasm (GO:0005737) 1.015KCTD7, PRICKLE1, TBC1D24, EPM2A, CSTB
cytosol (GO:0005829) 1.685KCTD7, PRICKLE1, EPM2A, NHLRC1, GOSR2
organelle membrane (GO:0031090) 1.975CERS1, PRICKLE1, LMNB2, SCARB2, GOSR2
membrane part (GO:0044425) 0.954CERS1, KCNC1, SCARB2, GOSR2
integral component of membrane (GO:0016021) 1.144CERS1, KCNC1, SCARB2, GOSR2
intrinsic component of membrane (GO:0031224) 1.134CERS1, KCNC1, SCARB2, GOSR2
macromolecular complex (GO:0032991) 1.353EPM2A, KCNC1, GOSR2
bounding membrane of organelle (GO:0098588) 2.393CERS1, SCARB2, GOSR2
nuclear part (GO:0044428) 1.553LMNB2, PRICKLE1, CSTB
endoplasmic reticulum (GO:0005783) 2.563EPM2A, CERS1, NHLRC1
plasma membrane (GO:0005886) 1.393EPM2A, KCNC1, KCTD7
protein complex (GO:0043234) 1.512KCNC1, GOSR2
Golgi apparatus (GO:0005794) 2.72CERS1, GOSR2
intracellular (GO:0005622) 2.372PRICKLE1, CSTB
extracellular organelle (GO:0043230) 1.892SCARB2, CSTB
vesicle (GO:0031982) 1.642SCARB2, CSTB
neuron part (GO:0097458) 2.642TBC1D24, KCNC1
vacuolar membrane (GO:0005774) 3.452SCARB2, GOSR2
whole membrane (GO:0098805) 2.852SCARB2, GOSR2
cell projection part (GO:0044463) 2.972TBC1D24, KCNC1
nuclear membrane (GO:0031965) 4.22LMNB2, PRICKLE1
extracellular vesicle (GO:1903561) 1.892SCARB2, CSTB
membrane-bounded vesicle (GO:0031988) 1.712SCARB2, CSTB
endoplasmic reticulum part (GO:0044432) 2.732CERS1, GOSR2
Golgi apparatus part (GO:0044431) 3.02CERS1, GOSR2
vacuolar part (GO:0044437) 3.262SCARB2, GOSR2
extracellular exosome (GO:0070062) 1.892SCARB2, CSTB
endoplasmic reticulum membrane (GO:0005789) 2.952CERS1, GOSR2
extracellular region part (GO:0044421) 1.572SCARB2, CSTB
membrane protein complex (GO:0098796) 2.842KCNC1, GOSR2
Golgi membrane (GO:0000139) 3.282CERS1, GOSR2