Disease ID | Disease name | Source of annotation with BARD1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
114480 | BREAST CANCER | OMIM | link to OMIM | 27 | RB1CC1, ESR1, NBN, PALB2, SLC22A18, BRIP1, BCPR, CASP8, FAM175A, TSG101, CHEK2, BARD1, TP53, AKT1, BRCA1, RAD51, PHB, PPM1D, NQO2, ATM, PIK3CA, BRCA2, CDH1, XRCC3, HMMR, KRAS, RAD54L |
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REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Cell Cycle | R-HSA-1640170 | 3.89 |
Cell Cycle Checkpoints | R-HSA-69620 | 5.64 |
G2/M DNA damage checkpoint | R-HSA-69473 | 7.15 |
G2/M Checkpoints | R-HSA-69481 | 6.46 |
GO term | GO ID | GO IC |
---|---|---|
enzyme binding | GO:0019899 | 2.27 |
zinc ion binding | GO:0008270 | 2.66 |
nucleic acid binding | GO:0003676 | 1.44 |
heterocyclic compound binding | GO:1901363 | 1.06 |
ubiquitin-like protein transferase activity | GO:0019787 | 3.69 |
cation binding | GO:0043169 | 1.4 |
transition metal ion binding | GO:0046914 | 2.48 |
ligase activity | GO:0016874 | 3.72 |
ion binding | GO:0043167 | 1.36 |
transferase activity | GO:0016740 | 1.95 |
metal ion binding | GO:0046872 | 1.41 |
identical protein binding | GO:0042802 | 2.63 |
protein homodimerization activity | GO:0042803 | 3.16 |
kinase binding | GO:0019900 | 3.32 |
ubiquitin-protein transferase activity | GO:0004842 | 3.73 |
catalytic activity | GO:0003824 | 1.05 |
organic cyclic compound binding | GO:0097159 | 1.05 |
RNA binding | GO:0003723 | 2.36 |
protein binding | GO:0005515 | 0.46 |
protein dimerization activity | GO:0046983 | 2.72 |
protein heterodimerization activity | GO:0046982 | 3.64 |
binding | GO:0005488 | 0.18 |