Gene table of RAD51 : RAD51 recombinase

Gene-disease associations table

Disease ID	Disease name	Source of annotation with RAD51	OMIM link	Number of associated genes	genes
114480	BREAST CANCER	OMIM, HUMSAVAR	link to OMIM	27	RB1CC1, ESR1, NBN, PALB2, SLC22A18, BRIP1, BCPR, CASP8, FAM175A, TSG101, CHEK2, BARD1, TP53, AKT1, BRCA1, RAD51, PHB, PPM1D, NQO2, ATM, PIK3CA, BRCA2, CDH1, XRCC3, HMMR, KRAS, RAD54L
PS157600	MIRROR MOVEMENTS	ClinVar, OMIM	link to OMIM	3	RAD51, DCC, DNAL4

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Annotation of the gene RAD51

Associated genes in ENSEMBL

ENSG00000051180

Associated proteins - SwissProt Accession ID

Q06609

Associated PDB IDs

Cytogenetic Band

15q15.1

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Pancreatic cancer	hsa05212	6.56
Homologous recombination	hsa03440	7.91
Fanconi anemia pathway	hsa03460	7.01
Pathways in cancer	hsa05200	3.98

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Homologous DNA Pairing and Strand Exchange	R-HSA-76010	10.18
DNA Repair	R-HSA-73894	5.8
Assembly of the RAD51-ssDNA nucleoprotein complex	R-HSA-76000	10.66
Homologous recombination repair of replication-independent double-strand breaks	R-HSA-73951	8.98
Presynaptic phase of homologous DNA pairing and strand exchange	R-HSA-76003	10.4
Meiotic recombination	R-HSA-912446	7.25
Meiosis	R-HSA-1500620	6.59
Homologous Recombination Repair	R-HSA-73888	8.98
Cell Cycle	R-HSA-1640170	3.89
Double-Strand Break Repair	R-HSA-73890	8.46

Associated GO terms for Molecular function

GO term	GO ID	GO IC
protein C-terminus binding	GO:0008022	4.5
ATPase activity	GO:0016887	3.65
purine ribonucleoside triphosphate binding	GO:0035639	2.22
deoxyribonuclease activity	GO:0004536	5.48
enzyme binding	GO:0019899	2.27
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
structure-specific DNA binding	GO:0043566	4.98
pyrophosphatase activity	GO:0016462	3.04
endodeoxyribonuclease activity	GO:0004520	5.81
nucleotide binding	GO:0000166	1.96
single-stranded DNA-dependent ATPase activity	GO:0043142	7.17
nucleoside phosphate binding	GO:1901265	1.96
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
double-stranded DNA binding	GO:0003690	3.09
single-stranded DNA binding	GO:0003697	5.17
ATP binding	GO:0005524	2.43
hydrolase activity	GO:0016787	1.9
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
DNA polymerase binding	GO:0070182	7.25
DNA secondary structure binding	GO:0000217	6.6
nucleoside-triphosphatase activity	GO:0017111	3.09
hydrolase activity, acting on ester bonds	GO:0016788	3.1
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
DNA-dependent ATPase activity	GO:0008094	5.31
four-way junction DNA binding	GO:0000400	7.03
adenyl nucleotide binding	GO:0030554	2.4
nuclease activity	GO:0004518	4.33
organic cyclic compound binding	GO:0097159	1.05
ATPase activity, coupled	GO:0042623	3.97
recombinase activity	GO:0000150	7.66
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
carbohydrate derivative binding	GO:0097367	2.03
adenyl ribonucleotide binding	GO:0032559	2.41
identical protein binding	GO:0042802	2.63
protein binding	GO:0005515	0.46
endonuclease activity	GO:0004519	4.78
purine ribonucleotide binding	GO:0032555	2.2
chromatin binding	GO:0003682	3.64
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19