Gene table of PPM1D : protein phosphatase, Mg2+/Mn2+ dependent 1D

Gene-disease associations table

Disease IDDisease nameSource of annotation with PPM1DOMIM linkNumber of associated genesgenes
114480BREAST CANCEROMIM link to OMIM 27RB1CC1, ESR1, NBN, PALB2, SLC22A18, BRIP1, BCPR, CASP8, FAM175A, TSG101, CHEK2, BARD1, TP53, AKT1, BRCA1, RAD51, PHB, PPM1D, NQO2, ATM, PIK3CA, BRCA2, CDH1, XRCC3, HMMR, KRAS, RAD54L

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Annotation of the gene PPM1D

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
p53 signaling pathwayhsa041156.56
Associated REACTOME pathways
Associated GO terms for Molecular function
GO termGO IDGO IC
phosphoprotein phosphatase activityGO:00047214.55
mitogen-activated protein kinase bindingGO:00510196.56
protein serine/threonine phosphatase activityGO:00047225.58
phosphatase activityGO:00167914.11
hydrolase activityGO:00167871.9
protein kinase bindingGO:00199013.44
catalytic activityGO:00038241.05
enzyme bindingGO:00198992.27
hydrolase activity, acting on ester bondsGO:00167883.1
ion bindingGO:00431671.36
phosphoric ester hydrolase activityGO:00425783.82
kinase bindingGO:00199003.32
cation bindingGO:00431691.4
bindingGO:00054880.18
protein bindingGO:00055150.46
metal ion bindingGO:00468721.41