| Disease ID | Disease name | Source of annotation with BCL10 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 137245 | LYMPHOMA, MUCOSA-ASSOCIATED LYMPHOID TYPE | OMIM | link to OMIM | 1 | BCL10 |
| 616098 | IMMUNODEFICIENCY 37 | ClinVar, OMIM | link to OMIM | 1 | BCL10 |
| 605027 | LYMPHOMA, NON-HODGKIN, FAMILIAL | OMIM | link to OMIM | 7 | BRAF, RAD54B, BCL10, PRF1, CASP10, TP53, RAD54L |
| 156240 | MESOTHELIOMA, MALIGNANT | OMIM | link to OMIM | 2 | WT1, BCL10 |
| 273300 | TESTICULAR GERM CELL TUMOR | ClinVar | link to OMIM | 5 | STK11, BCL10, KIT, FGFR3, STK10 |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| T cell receptor signaling pathway | hsa04660 | 6.01 |
| NF-kappa B signaling pathway | hsa04064 | 6.21 |
| B cell receptor signaling pathway | hsa04662 | 6.52 |
| Tuberculosis | hsa05152 | 5.17 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| C-type lectin receptors (CLRs) | R-HSA-5621481 | 6.06 |
| Downstream TCR signaling | R-HSA-202424 | 7.01 |
| Fc epsilon receptor (FCERI) signaling | R-HSA-2454202 | 4.03 |
| Innate Immune System | R-HSA-168249 | 3.17 |
| Immune System | R-HSA-168256 | 2.37 |
| Signaling by the B Cell Receptor (BCR) | R-HSA-983705 | 4.62 |
| Adaptive Immune System | R-HSA-1280218 | 3.19 |
| CLEC7A (Dectin-1) signaling | R-HSA-5607764 | 6.38 |
| Downstream signaling events of B Cell Receptor (BCR) | R-HSA-1168372 | 5.59 |
| Activation of NF-kappaB in B cells | R-HSA-1169091 | 6.94 |
| TCR signaling | R-HSA-202403 | 6.64 |
| FCERI mediated NF-kB activation | R-HSA-2871837 | 5.11 |
| GO term | GO ID | GO IC |
|---|---|---|
| protein C-terminus binding | GO:0008022 | 4.5 |
| ubiquitin-like protein ligase binding | GO:0044389 | 4.15 |
| kinase regulator activity | GO:0019207 | 4.5 |
| kinase activator activity | GO:0019209 | 5.58 |
| enzyme binding | GO:0019899 | 2.27 |
| binding | GO:0005488 | 0.18 |
| molecular function regulator | GO:0098772 | 2.51 |
| protein kinase B binding | GO:0043422 | 7.44 |
| transcription coactivator activity | GO:0003713 | 4.04 |
| transcription cofactor activity | GO:0003712 | 3.44 |
| transcription factor activity, transcription factor binding | GO:0000989 | 3.36 |
| transcription factor activity, protein binding | GO:0000988 | 3.35 |
| transcription factor binding | GO:0008134 | 3.46 |
| protease binding | GO:0002020 | 5.08 |
| enzyme regulator activity | GO:0030234 | 2.85 |
| NF-kappaB binding | GO:0051059 | 6.34 |
| protein kinase binding | GO:0019901 | 3.44 |
| kinase binding | GO:0019900 | 3.32 |
| protein self-association | GO:0043621 | 5.93 |
| ubiquitin protein ligase binding | GO:0031625 | 4.17 |
| ubiquitin-like protein binding | GO:0032182 | 4.93 |
| ubiquitin binding | GO:0043130 | 5.09 |
| protein binding | GO:0005515 | 0.46 |
| enzyme activator activity | GO:0008047 | 3.56 |