Disease table of MESOTHELIOMA, MALIGNANT OMIM ID: 156240

Gene-disease associations table

GeneAssociated with MESOTHELIOMA, MALIGNANT inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
WT1OMIMHGNC link11p136194080, PS194070, PS256300, 608978, 156240, 136680
BCL10OMIMHGNC link1p22.35273300, 156240, 137245, 605027, 616098

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
WT1YES51MYC, NR5A1, CTGF, AR, CD97, TBXA2R, MYB, EGFR, HBEGF, DNMT3A, ITGAX, CCNE1, ABCB1, EREG, THBS1, CIAO1, NOV, NDRG2, SMAD3, CD14, SNAI2, NPHS1, CDKN1A, PDGFA, TERT, IRF8, VDR, PODXL, CDH1, STIM1, JUN, CKM, AMH, CYP19A1, VEGFA, VEGFB, ODC1, ETS1, KLK3, JUNB, BCL2, IGF1R, PAX2, IGF2, IL2RB, MYCN, IGF1, SRY, UBE2I, CX3CL1, CAMP0
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
WT1YES10ZHX3, EP300, IFI16, PAX2, TFCP2, GATA1, RELA, PAX8, NFKB1, GATA20
Interactions from BIOGRID - physical
Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
WT1BCL10No-1AKT1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.182WT1, BCL10
protein binding (GO:0005515) 0.462WT1, BCL10
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.562WT1, BCL10
positive regulation of metabolic process (GO:0009893) 1.742WT1, BCL10
regulation of metabolic process (GO:0019222) 1.022WT1, BCL10
positive regulation of biosynthetic process (GO:0009891) 2.292WT1, BCL10
regulation of protein metabolic process (GO:0051246) 1.932WT1, BCL10
positive regulation of cellular metabolic process (GO:0031325) 1.812WT1, BCL10
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.292WT1, BCL10
regulation of cellular metabolic process (GO:0031323) 1.072WT1, BCL10
metabolic process (GO:0008152) 0.582WT1, BCL10
positive regulation of gene expression (GO:0010628) 2.352WT1, BCL10
positive regulation of cell death (GO:0010942) 3.322WT1, BCL10
regulation of cell death (GO:0010941) 2.432WT1, BCL10
regulation of apoptotic process (GO:0042981) 2.52WT1, BCL10
regulation of biological process (GO:0050789) 0.452WT1, BCL10
single-organism process (GO:0044699) 0.482WT1, BCL10
regulation of primary metabolic process (GO:0080090) 1.082WT1, BCL10
cellular response to stimulus (GO:0051716) 1.972WT1, BCL10
positive regulation of macromolecule metabolic process (GO:0010604) 1.812WT1, BCL10
regulation of gene expression (GO:0010468) 1.372WT1, BCL10
positive regulation of multicellular organismal process (GO:0051240) 2.492WT1, BCL10
positive regulation of cellular biosynthetic process (GO:0031328) 2.32WT1, BCL10
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.462WT1, BCL10
cellular component organization (GO:0016043) 1.242WT1, BCL10
positive regulation of apoptotic process (GO:0043065) 3.382WT1, BCL10
organic substance metabolic process (GO:0071704) 0.632WT1, BCL10
regulation of programmed cell death (GO:0043067) 2.492WT1, BCL10
negative regulation of apoptotic process (GO:0043066) 3.042WT1, BCL10
biological regulation (GO:0065007) 0.392WT1, BCL10
cellular component organization or biogenesis (GO:0071840) 1.222WT1, BCL10
positive regulation of transcription, DNA-templated (GO:0045893) 2.562WT1, BCL10
regulation of cellular biosynthetic process (GO:0031326) 1.382WT1, BCL10
positive regulation of biological process (GO:0048518) 1.22WT1, BCL10
negative regulation of biological process (GO:0048519) 1.332WT1, BCL10
negative regulation of programmed cell death (GO:0043069) 3.022WT1, BCL10
positive regulation of programmed cell death (GO:0043068) 3.382WT1, BCL10
anatomical structure formation involved in morphogenesis (GO:0048646) 3.012WT1, BCL10
developmental process (GO:0032502) 1.362WT1, BCL10
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.352WT1, BCL10
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.432WT1, BCL10
negative regulation of cell death (GO:0060548) 2.952WT1, BCL10
cellular process (GO:0009987) 0.262WT1, BCL10
regulation of biosynthetic process (GO:0009889) 1.372WT1, BCL10
regulation of nucleic acid-templated transcription (GO:1903506) 1.552WT1, BCL10
regulation of cellular process (GO:0050794) 0.52WT1, BCL10
single-organism developmental process (GO:0044767) 1.492WT1, BCL10
biosynthetic process (GO:0009058) 1.322WT1, BCL10
single-organism cellular process (GO:0044763) 0.652WT1, BCL10
regulation of nitrogen compound metabolic process (GO:0051171) 1.362WT1, BCL10
regulation of multicellular organismal process (GO:0051239) 1.872WT1, BCL10
regulation of RNA biosynthetic process (GO:2001141) 1.552WT1, BCL10
response to chemical (GO:0042221) 1.982WT1, BCL10
response to organic substance (GO:0010033) 2.22WT1, BCL10
primary metabolic process (GO:0044238) 0.692WT1, BCL10
regulation of cellular protein metabolic process (GO:0032268) 1.992WT1, BCL10
regulation of macromolecule metabolic process (GO:0060255) 1.082WT1, BCL10
response to stimulus (GO:0050896) 1.222WT1, BCL10
regulation of RNA metabolic process (GO:0051252) 1.522WT1, BCL10
positive regulation of RNA metabolic process (GO:0051254) 2.512WT1, BCL10
macromolecule metabolic process (GO:0043170) 0.832WT1, BCL10
positive regulation of RNA biosynthetic process (GO:1902680) 2.542WT1, BCL10
regulation of transcription, DNA-templated (GO:0006355) 1.562WT1, BCL10
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.392WT1, BCL10
regulation of macromolecule biosynthetic process (GO:0010556) 1.432WT1, BCL10
negative regulation of cellular process (GO:0048523) 1.412WT1, BCL10
positive regulation of cellular process (GO:0048522) 1.32WT1, BCL10
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cytoplasm (GO:0005737) 1.012WT1, BCL10
intracellular membrane-bounded organelle (GO:0043231) 0.62WT1, BCL10
nucleus (GO:0005634) 1.072WT1, BCL10
cell part (GO:0044464) 0.112WT1, BCL10
intracellular organelle part (GO:0044446) 0.812WT1, BCL10
intracellular organelle (GO:0043229) 0.512WT1, BCL10
intracellular part (GO:0044424) 0.282WT1, BCL10
membrane-bounded organelle (GO:0043227) 0.472WT1, BCL10
organelle (GO:0043226) 0.42WT1, BCL10
organelle part (GO:0044422) 0.792WT1, BCL10