Disease ID | Disease name | Source of annotation with CR1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
611162 | MALARIA, SUSCEPTIBILITY TO | OMIM | link to OMIM | 16 | FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA |
607486 | KNOPS BLOOD GROUP SYSTEM | OMIM | link to OMIM | 1 | CR1 |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Complement and coagulation cascades | hsa04610 | 6.58 |
Legionellosis | hsa05134 | 6.88 |
Leishmaniasis | hsa05140 | 6.32 |
Malaria | hsa05144 | 7.15 |
Tuberculosis | hsa05152 | 5.17 |
Hematopoietic cell lineage | hsa04640 | 6.18 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Complement cascade | R-HSA-166658 | 5.38 |
Innate Immune System | R-HSA-168249 | 3.17 |
Regulation of Complement cascade | R-HSA-977606 | 8.4 |
Immune System | R-HSA-168256 | 2.37 |
GO term | GO ID | GO IC |
---|---|---|
signaling receptor activity | GO:0038023 | 2.49 |
protein binding | GO:0005515 | 0.46 |
complement binding | GO:0001848 | 6.79 |
complement component C4b binding | GO:0001855 | 9.05 |
virus receptor activity | GO:0001618 | 5.49 |
complement component C4b receptor activity | GO:0001861 | 9.74 |
complement component C3b receptor activity | GO:0004877 | 9.74 |
molecular transducer activity | GO:0060089 | 2.32 |
transmembrane signaling receptor activity | GO:0004888 | 2.57 |
receptor activity | GO:0004872 | 2.32 |
signal transducer activity | GO:0004871 | 2.28 |
opsonin binding | GO:0001846 | 7.34 |
complement receptor activity | GO:0004875 | 8.35 |
complement component C3b binding | GO:0001851 | 9.05 |
transmembrane receptor activity | GO:0099600 | 2.53 |
opsonin receptor activity | GO:0001847 | 8.64 |
binding | GO:0005488 | 0.18 |