Gene table of CR1 : complement C3b/C4b receptor 1 (Knops blood group)

Gene-disease associations table

Disease IDDisease nameSource of annotation with CR1OMIM linkNumber of associated genesgenes
611162MALARIA, SUSCEPTIBILITY TOOMIM link to OMIM 16FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA
607486KNOPS BLOOD GROUP SYSTEMOMIM link to OMIM 1CR1

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Annotation of the gene CR1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Complement and coagulation cascadeshsa046106.58
Legionellosishsa051346.88
Leishmaniasishsa051406.32
Malariahsa051447.15
Tuberculosishsa051525.17
Hematopoietic cell lineagehsa046406.18
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Complement cascadeR-HSA-1666585.38
Innate Immune SystemR-HSA-1682493.17
Regulation of Complement cascadeR-HSA-9776068.4
Immune SystemR-HSA-1682562.37
Associated GO terms for Molecular function
GO termGO IDGO IC
signaling receptor activityGO:00380232.49
protein bindingGO:00055150.46
complement bindingGO:00018486.79
complement component C4b bindingGO:00018559.05
virus receptor activityGO:00016185.49
complement component C4b receptor activityGO:00018619.74
complement component C3b receptor activityGO:00048779.74
molecular transducer activityGO:00600892.32
transmembrane signaling receptor activityGO:00048882.57
receptor activityGO:00048722.32
signal transducer activityGO:00048712.28
opsonin bindingGO:00018467.34
complement receptor activityGO:00048758.35
complement component C3b bindingGO:00018519.05
transmembrane receptor activityGO:00996002.53
opsonin receptor activityGO:00018478.64
bindingGO:00054880.18