| Disease ID | Disease name | Source of annotation with NOS2 | OMIM link | Number of associated genes | genes |
|---|---|---|---|---|---|
| 611162 | MALARIA, SUSCEPTIBILITY TO | OMIM | link to OMIM | 16 | FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA |
| 145500 | HYPERTENSION, ESSENTIAL | OMIM | link to OMIM | 13 | RGS5, PTGIS, ADD1, NOS3, UMOD, AGT, ECE1, CYP3A5, ATP1B1, NOS2, GNB3, AGTR1, SELE |
Download the gene annotation in CSV format
| KEGG pathway | KEGG ID | KEGG IC |
|---|---|---|
| Pertussis | hsa05133 | 6.46 |
| Salmonella infection | hsa05132 | 6.29 |
| Arginine and proline metabolism | hsa00330 | 6.84 |
| Metabolic pathways | hsa01100 | 2.49 |
| Toxoplasmosis | hsa05145 | 5.71 |
| Pathways in cancer | hsa05200 | 3.98 |
| Tuberculosis | hsa05152 | 5.17 |
| Chagas disease (American trypanosomiasis) | hsa05142 | 5.99 |
| Leishmaniasis | hsa05140 | 6.32 |
| Amoebiasis | hsa05146 | 5.82 |
| Small cell lung cancer | hsa05222 | 6.17 |
| Peroxisome | hsa04146 | 6.34 |
| HIF-1 signaling pathway | hsa04066 | 5.9 |
| Calcium signaling pathway | hsa04020 | 5.22 |
| REACTOME pathway | REACTOME ID | REACTOME IC |
|---|---|---|
| Infectious disease | R-HSA-5663205 | 4.47 |
| Phagosomal maturation (early endosomal stage) | R-HSA-1222556 | 7.89 |
| Platelet homeostasis | R-HSA-418346 | 6.68 |
| Nitric oxide stimulates guanylate cyclase | R-HSA-392154 | 8.34 |
| Latent infection of Homo sapiens with Mycobacterium tuberculosis | R-HSA-1222352 | 7.89 |
| Hemostasis | R-HSA-109582 | 3.98 |
| Disease | R-HSA-1643685 | 3.33 |
| GO term | GO ID | GO IC |
|---|---|---|
| monooxygenase activity | GO:0004497 | 5.1 |
| binding | GO:0005488 | 0.18 |
| nucleotide binding | GO:0000166 | 1.96 |
| amino acid binding | GO:0016597 | 5.71 |
| heterocyclic compound binding | GO:1901363 | 1.06 |
| nucleoside phosphate binding | GO:1901265 | 1.96 |
| oxidoreductase activity | GO:0016491 | 3.12 |
| anion binding | GO:0043168 | 4.17 |
| coenzyme binding | GO:0050662 | 4.53 |
| NADP binding | GO:0050661 | 5.93 |
| flavin adenine dinucleotide binding | GO:0050660 | 5.41 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen | GO:0016709 | 6.07 |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | GO:0016705 | 4.65 |
| ion binding | GO:0043167 | 1.36 |
| FMN binding | GO:0010181 | 7.03 |
| metal ion binding | GO:0046872 | 1.41 |
| identical protein binding | GO:0042802 | 2.63 |
| protein homodimerization activity | GO:0042803 | 3.16 |
| arginine binding | GO:0034618 | 7.79 |
| heme binding | GO:0020037 | 4.86 |
| cation binding | GO:0043169 | 1.4 |
| tetrahydrobiopterin binding | GO:0034617 | 8.35 |
| small molecule binding | GO:0036094 | 1.89 |
| catalytic activity | GO:0003824 | 1.05 |
| cofactor binding | GO:0048037 | 4.16 |
| protein dimerization activity | GO:0046983 | 2.72 |
| nitric-oxide synthase activity | GO:0004517 | 8.64 |
| carbohydrate derivative binding | GO:0097367 | 2.03 |
| organic cyclic compound binding | GO:0097159 | 1.05 |
| tetrapyrrole binding | GO:0046906 | 4.8 |
| carboxylic acid binding | GO:0031406 | 4.64 |
| calmodulin binding | GO:0005516 | 4.55 |
| protein binding | GO:0005515 | 0.46 |
| receptor binding | GO:0005102 | 2.43 |
| ribonucleotide binding | GO:0032553 | 2.19 |