Gene table of FCGR2B : Fc fragment of IgG receptor IIb

Gene-disease associations table

Disease IDDisease nameSource of annotation with FCGR2BOMIM linkNumber of associated genesgenes
152700SYSTEMIC LUPUS ERYTHEMATOSUSOMIM link to OMIM 6FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1
611162MALARIA, SUSCEPTIBILITY TOOMIM link to OMIM 16FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA

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Annotation of the gene FCGR2B

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation

The gene is in the tandem Group 78, together with the genes:

Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Osteoclast differentiationhsa043805.64
B cell receptor signaling pathwayhsa046626.52
Phagosomehsa041455.27
Staphylococcus aureus infectionhsa051506.64
Fc gamma R-mediated phagocytosishsa046666.21
Tuberculosishsa051525.17
Measleshsa051625.6
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Immune SystemR-HSA-1682562.37
Adaptive Immune SystemR-HSA-12802183.19
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellR-HSA-1989334.7
Associated GO terms for Molecular function
GO termGO IDGO IC
IgG bindingGO:00198647.34
immunoglobulin bindingGO:00198656.6
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
protein bindingGO:00055150.46
protein complex bindingGO:00324033.09