Gene table of FCGR2A : Fc fragment of IgG receptor IIa

Gene-disease associations table

Disease IDDisease nameSource of annotation with FCGR2AOMIM linkNumber of associated genesgenes
152700SYSTEMIC LUPUS ERYTHEMATOSUSOMIM link to OMIM 6FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1
611162MALARIA, SUSCEPTIBILITY TOOMIM link to OMIM 16FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA
219700CYSTIC FIBROSISOMIM link to OMIM 3TGFB1, FCGR2A, CFTR

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Annotation of the gene FCGR2A

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation

The gene is in the tandem Group 78, together with the genes:

Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Platelet activationhsa046115.66
Systemic lupus erythematosushsa053225.95
Tuberculosishsa051525.17
Leishmaniasishsa051406.32
Phagosomehsa041455.27
Staphylococcus aureus infectionhsa051506.64
Fc gamma R-mediated phagocytosishsa046666.21
Osteoclast differentiationhsa043805.64
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Role of phospholipids in phagocytosisR-HSA-20294855.47
Fcgamma receptor (FCGR) dependent phagocytosisR-HSA-20294805.07
FCGR activationR-HSA-20294815.58
Regulation of actin dynamics for phagocytic cup formationR-HSA-20294825.23
Immune SystemR-HSA-1682562.37
Innate Immune SystemR-HSA-1682493.17
Associated GO terms for Molecular function
GO termGO IDGO IC
IgG bindingGO:00198647.34
immunoglobulin bindingGO:00198656.6
macromolecular complex bindingGO:00448772.61
bindingGO:00054880.18
protein bindingGO:00055150.46
protein complex bindingGO:00324033.09