Disease ID | Disease name | Source of annotation with FCGR2A | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
152700 | SYSTEMIC LUPUS ERYTHEMATOSUS | OMIM | link to OMIM | 6 | FCGR2A, PTPN22, CTLA4, TREX1, FCGR2B, DNASE1 |
611162 | MALARIA, SUSCEPTIBILITY TO | OMIM | link to OMIM | 16 | FCGR2A, TIRAP, ICAM1, ACKR1, G6PD, GYPC, TNF, SLC4A1, NOS2, HBB, CISH, GYPB, FCGR2B, CR1, CD36, GYPA |
219700 | CYSTIC FIBROSIS | OMIM | link to OMIM | 3 | TGFB1, FCGR2A, CFTR |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Platelet activation | hsa04611 | 5.66 |
Systemic lupus erythematosus | hsa05322 | 5.95 |
Tuberculosis | hsa05152 | 5.17 |
Leishmaniasis | hsa05140 | 6.32 |
Phagosome | hsa04145 | 5.27 |
Staphylococcus aureus infection | hsa05150 | 6.64 |
Fc gamma R-mediated phagocytosis | hsa04666 | 6.21 |
Osteoclast differentiation | hsa04380 | 5.64 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Role of phospholipids in phagocytosis | R-HSA-2029485 | 5.47 |
Fcgamma receptor (FCGR) dependent phagocytosis | R-HSA-2029480 | 5.07 |
FCGR activation | R-HSA-2029481 | 5.58 |
Regulation of actin dynamics for phagocytic cup formation | R-HSA-2029482 | 5.23 |
Immune System | R-HSA-168256 | 2.37 |
Innate Immune System | R-HSA-168249 | 3.17 |
GO term | GO ID | GO IC |
---|---|---|
IgG binding | GO:0019864 | 7.34 |
immunoglobulin binding | GO:0019865 | 6.6 |
macromolecular complex binding | GO:0044877 | 2.61 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
protein complex binding | GO:0032403 | 3.09 |