Disease table of PALMOPLANTAR KERATODERMA, EPIDERMOLYTIC OMIM ID: 144200

Gene-disease associations table

GeneAssociated with PALMOPLANTAR KERATODERMA, EPIDERMOLYTIC inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
KRT1ClinVar, OMIMHGNC link12q13.136144200, 113800, 607602, 607654, 146590, 600962
KRT9ClinVar, OMIM, HUMSAVARHGNC link17q21.21144200

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
KRT1KRT9Yes42UBASH3B, FN1, NPHP4, AP2M1, CUL4B, CUL1, EIF4A3, DCUN1D1, INPPL1, CUL4A, APOA1, HNRNPA1, PAN2, COPS6, MAGOH, CRK, VCAM1, PIK3R2, IQCB1, POU5F1, RPS6KB2, COPS5, SHC1, UCHL5, ITGA4, EPS15, ADRB2, CEP290, CDH1, NPHP1, CUL2, UBE3A, INVS, CUL5, NEDD8, CBL, ALB, CAND1, CUL3, GRB2, YWHAQ, LGR4

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
KRT1KRT9No-1MAGOH

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
KRT1KRT9Yes0

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
structural molecule activity (GO:0005198) 3.12KRT1, KRT9

NET-GE enrichment

Term New enriched termICP valueGenes
structural molecule activity (GO:0005198) -3.10.011KRT1, KRT9
GO - biological process annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
single-organism process (GO:0044699) 0.482KRT1, KRT9
GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
intracellular membrane-bounded organelle (GO:0043231) 0.62KRT9, KRT1
supramolecular fiber (GO:0099512) 3.312KRT1, KRT9
extracellular space (GO:0005615) 2.632KRT1, KRT9
extracellular region part (GO:0044421) 1.572KRT9, KRT1
extracellular exosome (GO:0070062) 1.892KRT9, KRT1
nucleus (GO:0005634) 1.072KRT1, KRT9
membrane (GO:0016020) 0.682KRT9, KRT1
cell part (GO:0044464) 0.112KRT9, KRT1
vesicle (GO:0031982) 1.642KRT1, KRT9
membrane-bounded vesicle (GO:0031988) 1.712KRT9, KRT1
intracellular organelle part (GO:0044446) 0.812KRT1, KRT9
intracellular organelle (GO:0043229) 0.512KRT1, KRT9
cytoskeletal part (GO:0044430) 2.492KRT1, KRT9
organelle part (GO:0044422) 0.792KRT1, KRT9
intracellular part (GO:0044424) 0.282KRT9, KRT1
extracellular organelle (GO:0043230) 1.892KRT1, KRT9
extracellular vesicle (GO:1903561) 1.892KRT1, KRT9
membrane-bounded organelle (GO:0043227) 0.472KRT9, KRT1
organelle (GO:0043226) 0.42KRT9, KRT1
intermediate filament (GO:0005882) 4.482KRT1, KRT9
polymeric cytoskeletal fiber (GO:0099513) 3.312KRT1, KRT9

NET-GE enrichment

Term New enriched termICP valueGenes
intermediate filament (GO:0005882) -4.480.006KRT1, KRT9