Disease table of HEART, MALFORMATION OF OMIM ID: 234750

Gene-disease associations table

GeneAssociated with HEART, MALFORMATION OF inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
MYH6ClinVarHGNC link14q11.26PS192600, 234750, PS108800, PS115200, 140500, PS608567
NOTCH1ClinVarHGNC link9q34.36PS109730, 130020, 154700, 234750, 140500, PS100300
TBX5ClinVarHGNC link12q24.213140500, 142900, 234750

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
TBX5YES5ITGA9, CDKN2A, NPPA, GJA5, MYH61MYH6
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
MYH6YES3JARID2, TBX5, ELK31TBX5
NOTCH1YES1SIRT10
TBX5YES1NKX2-50
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction
NOTCH1TBX5No2KAT5, SMARCA4

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Gene1Gene2Direct InteractionInteraction modeNumber of shared interactorsShared genes in interaction
MYH6NOTCH1No-4MYOD1, UBC, JARID2, MYH11
NOTCH1TBX5No-6KAT2B, STAT3, MEF2A, FGF10, WNT2B, CTNNB1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG termKEGG term IDICNumber of genes with the same termGenes
Thyroid hormone signaling pathwayhsa049195.822NOTCH1, MYH6

NET-GE enrichment

Term New enriched termICP valueGenes
Thyroid hormone signaling pathway (hsa04919) -5.820.007NOTCH1, MYH6
REACTOME pathways annotation: shared terms (no NET-GE enrichment)

Shared terms

REACTOME termREACTOME term IDICNumber of genes with the same termGenes
Generic Transcription PathwayR-HSA-2124363.862NOTCH1, TBX5
Gene ExpressionR-HSA-741602.722NOTCH1, TBX5
GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
organic cyclic compound binding (GO:0097159) 1.053NOTCH1, TBX5, MYH6
heterocyclic compound binding (GO:1901363) 1.063NOTCH1, TBX5, MYH6
protein binding (GO:0005515) 0.463NOTCH1, TBX5, MYH6
binding (GO:0005488) 0.183NOTCH1, TBX5, MYH6
transcription regulatory region DNA binding (GO:0044212) 3.032NOTCH1, TBX5
sequence-specific DNA binding (GO:0043565) 2.792NOTCH1, TBX5
transcription factor activity, sequence-specific DNA binding (GO:0003700) 2.652NOTCH1, TBX5
regulatory region DNA binding (GO:0000975) 3.032NOTCH1, TBX5
regulatory region nucleic acid binding (GO:0001067) 3.032NOTCH1, TBX5
enzyme binding (GO:0019899) 2.272NOTCH1, MYH6
nucleic acid binding transcription factor activity (GO:0001071) 2.652NOTCH1, TBX5
nucleic acid binding (GO:0003676) 1.442NOTCH1, TBX5
DNA binding (GO:0003677) 1.922NOTCH1, TBX5

NET-GE enrichment

Term New enriched termICP valueGenes
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription (GO:0001190) NEW5.770.012NOTCH1, TBX5
transcription coactivator activity (GO:0003713) NEW4.040.014NOTCH1, TBX5, MYH6
RNA polymerase II regulatory region DNA binding (GO:0001012) NEW3.360.017NOTCH1, TBX5, MYH6
RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (GO:0001228) NEW3.980.007NOTCH1, TBX5, MYH6
transcription regulatory region sequence-specific DNA binding (GO:0000976) NEW3.240.025NOTCH1, TBX5, MYH6
RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977) NEW3.370.017NOTCH1, TBX5, MYH6
sequence-specific DNA binding RNA polymerase II transcription factor activity (GO:0000981) NEW3.290.041NOTCH1, TBX5, MYH6
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
regulation of developmental growth (GO:0048638) 4.043NOTCH1, TBX5, MYH6
regulation of RNA metabolic process (GO:0051252) 1.523NOTCH1, TBX5, MYH6
regulation of primary metabolic process (GO:0080090) 1.083NOTCH1, TBX5, MYH6
regulation of metabolic process (GO:0019222) 1.023NOTCH1, TBX5, MYH6
regulation of cellular biosynthetic process (GO:0031326) 1.383NOTCH1, TBX5, MYH6
regulation of cellular metabolic process (GO:0031323) 1.073NOTCH1, TBX5, MYH6
movement of cell or subcellular component (GO:0006928) 2.613NOTCH1, TBX5, MYH6
metabolic process (GO:0008152) 0.583NOTCH1, TBX5, MYH6
cellular nitrogen compound metabolic process (GO:0034641) 1.223NOTCH1, TBX5, MYH6
nitrogen compound metabolic process (GO:0006807) 1.133NOTCH1, TBX5, MYH6
anatomical structure morphogenesis (GO:0009653) 2.533NOTCH1, TBX5, MYH6
regulation of biological process (GO:0050789) 0.453NOTCH1, TBX5, MYH6
single-organism process (GO:0044699) 0.483NOTCH1, TBX5, MYH6
nucleobase-containing compound metabolic process (GO:0006139) 1.353NOTCH1, TBX5, MYH6
cellular macromolecule metabolic process (GO:0044260) 0.933NOTCH1, TBX5, MYH6
regulation of transcription from RNA polymerase II promoter (GO:0006357) 2.243NOTCH1, TBX5, MYH6
cellular developmental process (GO:0048869) 1.823NOTCH1, TBX5, MYH6
regulation of growth (GO:0040008) 3.263NOTCH1, TBX5, MYH6
regulation of cellular macromolecule biosynthetic process (GO:2000112) 1.463NOTCH1, TBX5, MYH6
multicellular organism development (GO:0007275) 2.543NOTCH1, TBX5, MYH6
regulation of developmental process (GO:0050793) 2.13NOTCH1, TBX5, MYH6
animal organ development (GO:0048513) 2.533NOTCH1, TBX5, MYH6
biological regulation (GO:0065007) 0.393NOTCH1, TBX5, MYH6
organic cyclic compound metabolic process (GO:1901360) 1.263NOTCH1, TBX5, MYH6
tissue morphogenesis (GO:0048729) 3.873NOTCH1, TBX5, MYH6
regulation of gene expression (GO:0010468) 1.373NOTCH1, TBX5, MYH6
anatomical structure formation involved in morphogenesis (GO:0048646) 3.013NOTCH1, TBX5, MYH6
developmental process (GO:0032502) 1.363NOTCH1, TBX5, MYH6
regulation of heart growth (GO:0060420) 5.973NOTCH1, TBX5, MYH6
multicellular organismal process (GO:0032501) 1.453NOTCH1, TBX5, MYH6
heart development (GO:0007507) 4.243NOTCH1, TBX5, MYH6
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.433NOTCH1, TBX5, MYH6
cellular aromatic compound metabolic process (GO:0006725) 1.33NOTCH1, TBX5, MYH6
cellular process (GO:0009987) 0.263NOTCH1, TBX5, MYH6
regulation of biosynthetic process (GO:0009889) 1.373NOTCH1, TBX5, MYH6
regulation of nucleic acid-templated transcription (GO:1903506) 1.553NOTCH1, TBX5, MYH6
regulation of cellular process (GO:0050794) 0.53NOTCH1, TBX5, MYH6
single-organism developmental process (GO:0044767) 1.493NOTCH1, TBX5, MYH6
organic substance metabolic process (GO:0071704) 0.633NOTCH1, TBX5, MYH6
regulation of organ growth (GO:0046620) 5.413NOTCH1, TBX5, MYH6
regulation of nitrogen compound metabolic process (GO:0051171) 1.363NOTCH1, TBX5, MYH6
regulation of multicellular organismal process (GO:0051239) 1.873NOTCH1, TBX5, MYH6
regulation of RNA biosynthetic process (GO:2001141) 1.553NOTCH1, TBX5, MYH6
heterocycle metabolic process (GO:0046483) 1.313NOTCH1, TBX5, MYH6
primary metabolic process (GO:0044238) 0.693NOTCH1, TBX5, MYH6
single-multicellular organism process (GO:0044707) 1.783NOTCH1, TBX5, MYH6
regulation of macromolecule metabolic process (GO:0060255) 1.083NOTCH1, TBX5, MYH6
anatomical structure development (GO:0048856) 1.583NOTCH1, TBX5, MYH6
cellular metabolic process (GO:0044237) 0.693NOTCH1, TBX5, MYH6
macromolecule metabolic process (GO:0043170) 0.833NOTCH1, TBX5, MYH6
regulation of transcription, DNA-templated (GO:0006355) 1.563NOTCH1, TBX5, MYH6
regulation of macromolecule biosynthetic process (GO:0010556) 1.433NOTCH1, TBX5, MYH6
regulation of multicellular organismal development (GO:2000026) 2.313NOTCH1, TBX5, MYH6
single-organism cellular process (GO:0044763) 0.653NOTCH1, TBX5, MYH6
limb morphogenesis (GO:0035108) 5.052NOTCH1, TBX5
regulation of stem cell differentiation (GO:2000736) 6.262NOTCH1, TBX5
appendage morphogenesis (GO:0035107) 5.052NOTCH1, TBX5
signal transduction (GO:0007165) 1.282NOTCH1, MYH6
cell surface receptor signaling pathway (GO:0007166) 2.092NOTCH1, MYH6
organic cyclic compound biosynthetic process (GO:1901362) 1.662NOTCH1, TBX5
cellular component organization or biogenesis (GO:0071840) 1.222NOTCH1, MYH6
morphogenesis of an epithelium (GO:0002009) 4.082NOTCH1, TBX5
positive regulation of macromolecule metabolic process (GO:0010604) 1.812NOTCH1, TBX5
regulation of cell proliferation involved in heart morphogenesis (GO:2000136) 7.022NOTCH1, TBX5
regulation of organ formation (GO:0003156) 6.262NOTCH1, TBX5
negative regulation of cell development (GO:0010721) 4.022NOTCH1, TBX5
positive regulation of biological process (GO:0048518) 1.22NOTCH1, TBX5
negative regulation of biological process (GO:0048519) 1.332NOTCH1, TBX5
regulation of cell proliferation (GO:0042127) 2.412NOTCH1, TBX5
regulation of striated muscle tissue development (GO:0016202) 5.092NOTCH1, TBX5
cell development (GO:0048468) 3.282NOTCH1, MYH6
cardiac ventricle formation (GO:0003211) 7.432NOTCH1, TBX5
positive regulation of muscle organ development (GO:0048636) 5.692NOTCH1, TBX5
positive regulation of cardiac muscle cell proliferation (GO:0060045) 6.782NOTCH1, TBX5
cell motility (GO:0048870) 3.022NOTCH1, TBX5
aromatic compound biosynthetic process (GO:0019438) 1.72NOTCH1, TBX5
cardiac septum morphogenesis (GO:0060411) 5.92NOTCH1, TBX5
muscle tissue morphogenesis (GO:0060415) 5.622NOTCH1, MYH6
regulation of cell morphogenesis (GO:0022604) 3.42NOTCH1, TBX5
positive regulation of metabolic process (GO:0009893) 1.742NOTCH1, TBX5
positive regulation of biosynthetic process (GO:0009891) 2.292NOTCH1, TBX5
heart valve morphogenesis (GO:0003179) 6.552NOTCH1, TBX5
positive regulation of gene expression (GO:0010628) 2.352NOTCH1, TBX5
regulation of apoptotic process (GO:0042981) 2.52NOTCH1, TBX5
nucleic acid-templated transcription (GO:0097659) 1.912NOTCH1, TBX5
cardiac muscle tissue development (GO:0048738) 6.332NOTCH1, TBX5
cardiac chamber formation (GO:0003207) 7.332NOTCH1, TBX5
cellular component organization (GO:0016043) 1.242NOTCH1, MYH6
transcription initiation from RNA polymerase II promoter (GO:0006367) 4.72NOTCH1, TBX5
transcription from RNA polymerase II promoter (GO:0006366) 3.382NOTCH1, TBX5
regulation of molecular function (GO:0065009) 1.782NOTCH1, MYH6
cell migration (GO:0016477) 3.122NOTCH1, TBX5
regulation of anatomical structure morphogenesis (GO:0022603) 2.792NOTCH1, TBX5
heterocycle biosynthetic process (GO:0018130) 1.72NOTCH1, TBX5
regulation of muscle tissue development (GO:1901861) 5.072NOTCH1, TBX5
positive regulation of muscle tissue development (GO:1901863) 5.672NOTCH1, TBX5
regulation of catalytic activity (GO:0050790) 1.972NOTCH1, MYH6
regulation of cardiac muscle tissue development (GO:0055024) 5.862NOTCH1, TBX5
positive regulation of cardiac muscle tissue development (GO:0055025) 6.332NOTCH1, TBX5
tissue development (GO:0009888) 3.272NOTCH1, TBX5
positive regulation of cardiac muscle tissue growth (GO:0055023) 6.592NOTCH1, TBX5
nucleobase-containing compound biosynthetic process (GO:0034654) 1.722NOTCH1, TBX5
regulation of cardiac muscle tissue growth (GO:0055021) 6.122NOTCH1, TBX5
RNA metabolic process (GO:0016070) 1.592NOTCH1, TBX5
cellular nitrogen compound biosynthetic process (GO:0044271) 1.592NOTCH1, TBX5
regulation of epithelial to mesenchymal transition (GO:0010717) 5.552NOTCH1, TBX5
regulation of cardioblast proliferation (GO:0003264) 7.532NOTCH1, TBX5
positive regulation of macromolecule biosynthetic process (GO:0010557) 2.392NOTCH1, TBX5
regulation of cell motility (GO:2000145) 3.162NOTCH1, TBX5
transcription, DNA-templated (GO:0006351) 1.912NOTCH1, TBX5
DNA-templated transcription, initiation (GO:0006352) 4.492NOTCH1, TBX5
atrioventricular valve morphogenesis (GO:0003181) 7.242NOTCH1, TBX5
positive regulation of developmental growth (GO:0048639) 4.672NOTCH1, TBX5
RNA biosynthetic process (GO:0032774) 1.842NOTCH1, TBX5
cell differentiation (GO:0030154) 2.142NOTCH1, TBX5
regulation of muscle organ development (GO:0048634) 5.072NOTCH1, TBX5
regulation of cellular component organization (GO:0051128) 2.012NOTCH1, TBX5
embryo development (GO:0009790) 4.22NOTCH1, MYH6
embryo development ending in birth or egg hatching (GO:0009792) 4.352NOTCH1, MYH6
cellular macromolecule biosynthetic process (GO:0034645) 1.662NOTCH1, TBX5
regulation of cardiac muscle cell proliferation (GO:0060043) 6.332NOTCH1, TBX5
positive regulation of striated muscle tissue development (GO:0045844) 5.692NOTCH1, TBX5
in utero embryonic development (GO:0001701) 4.42NOTCH1, MYH6
positive regulation of multicellular organismal process (GO:0051240) 2.492NOTCH1, TBX5
negative regulation of multicellular organismal process (GO:0051241) 2.842NOTCH1, TBX5
regulation of cell development (GO:0060284) 3.012NOTCH1, TBX5
endocardial cushion development (GO:0003197) 7.332NOTCH1, TBX5
regulation of cell morphogenesis involved in differentiation (GO:0010769) 3.912NOTCH1, TBX5
chordate embryonic development (GO:0043009) 4.382NOTCH1, MYH6
positive regulation of cell proliferation (GO:0008284) 3.012NOTCH1, TBX5
negative regulation of cell proliferation (GO:0008285) 3.262NOTCH1, TBX5
positive regulation of heart growth (GO:0060421) 6.432NOTCH1, TBX5
cardiac cell development (GO:0055006) 6.332NOTCH1, MYH6
cardiac muscle tissue morphogenesis (GO:0055008) 5.82NOTCH1, MYH6
epithelium development (GO:0060429) 4.572NOTCH1, TBX5
negative regulation of cellular component movement (GO:0051271) 4.222NOTCH1, TBX5
positive regulation of cell differentiation (GO:0045597) 3.012NOTCH1, TBX5
negative regulation of cell differentiation (GO:0045596) 3.332NOTCH1, TBX5
regulation of cell differentiation (GO:0045595) 2.422NOTCH1, TBX5
regulation of cellular component movement (GO:0051270) 3.082NOTCH1, TBX5
positive regulation of transcription, DNA-templated (GO:0045893) 2.562NOTCH1, TBX5
regulation of localization (GO:0032879) 1.942NOTCH1, TBX5
negative regulation of developmental process (GO:0051093) 3.172NOTCH1, TBX5
positive regulation of developmental process (GO:0051094) 2.772NOTCH1, TBX5
positive regulation of RNA metabolic process (GO:0051254) 2.512NOTCH1, TBX5
positive regulation of RNA biosynthetic process (GO:1902680) 2.542NOTCH1, TBX5
positive regulation of transcription from RNA polymerase II promoter (GO:0045944) 2.812NOTCH1, TBX5
positive regulation of nucleic acid-templated transcription (GO:1903508) 2.562NOTCH1, TBX5
lung development (GO:0030324) 5.132NOTCH1, TBX5
positive regulation of growth (GO:0045927) 4.252NOTCH1, TBX5
embryonic limb morphogenesis (GO:0030326) 5.242NOTCH1, TBX5
ventricular cardiac muscle tissue morphogenesis (GO:0055010) 6.072NOTCH1, MYH6
positive regulation of cellular metabolic process (GO:0031325) 1.812NOTCH1, TBX5
nucleic acid metabolic process (GO:0090304) 1.462NOTCH1, TBX5
striated muscle tissue development (GO:0014706) 5.232NOTCH1, TBX5
cell migration involved in heart development (GO:0060973) 7.092NOTCH1, TBX5
positive regulation of cellular biosynthetic process (GO:0031328) 2.32NOTCH1, TBX5
regulation of cell death (GO:0010941) 2.432NOTCH1, TBX5
pattern specification process (GO:0007389) 3.792NOTCH1, TBX5
muscle cell development (GO:0055001) 5.292NOTCH1, MYH6
regulation of programmed cell death (GO:0043067) 2.492NOTCH1, TBX5
embryonic morphogenesis (GO:0048598) 3.722NOTCH1, TBX5
negative regulation of cell migration (GO:0030336) 4.412NOTCH1, TBX5
regulation of cell migration (GO:0030334) 3.232NOTCH1, TBX5
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 2.352NOTCH1, TBX5
organic substance biosynthetic process (GO:1901576) 1.342NOTCH1, TBX5
positive regulation of organ growth (GO:0046622) 6.092NOTCH1, TBX5
negative regulation of cell motility (GO:2000146) 4.362NOTCH1, TBX5
cardiocyte differentiation (GO:0035051) 6.022NOTCH1, TBX5
biosynthetic process (GO:0009058) 1.322NOTCH1, TBX5
macromolecule biosynthetic process (GO:0009059) 1.612NOTCH1, TBX5
embryonic appendage morphogenesis (GO:0035113) 5.242NOTCH1, TBX5
mesenchyme development (GO:0060485) 5.72NOTCH1, TBX5
regulation of heart morphogenesis (GO:2000826) 6.42NOTCH1, TBX5
locomotion (GO:0040011) 2.912NOTCH1, TBX5
negative regulation of locomotion (GO:0040013) 4.222NOTCH1, TBX5
regulation of locomotion (GO:0040012) 3.122NOTCH1, TBX5
positive regulation of nitrogen compound metabolic process (GO:0051173) 2.292NOTCH1, TBX5
regulation of organ morphogenesis (GO:2000027) 4.222NOTCH1, TBX5
muscle tissue development (GO:0060537) 5.12NOTCH1, TBX5
cellular biosynthetic process (GO:0044249) 1.372NOTCH1, TBX5
negative regulation of cellular process (GO:0048523) 1.412NOTCH1, TBX5
positive regulation of cellular process (GO:0048522) 1.32NOTCH1, TBX5

NET-GE enrichment

Term New enriched termICP valueGenes
regulation of developmental growth (GO:0048638) -4.040.036NOTCH1, TBX5, MYH6
limb morphogenesis (GO:0035108) -5.050.006NOTCH1, TBX5, MYH6
lung development (GO:0030324) -5.130.038NOTCH1, TBX5
embryonic limb morphogenesis (GO:0030326) -5.240.004NOTCH1, TBX5, MYH6
ventricular cardiac muscle tissue morphogenesis (GO:0055010) -6.070.008NOTCH1, MYH6
cell migration involved in gastrulation (GO:0042074) NEW7.240.015NOTCH1, MYH6
positive regulation of striated muscle cell differentiation (GO:0051155) NEW5.720.0NOTCH1, TBX5, MYH6
appendage morphogenesis (GO:0035107) -5.050.006NOTCH1, TBX5, MYH6
regulation of heart growth (GO:0060420) -5.970.0NOTCH1, TBX5, MYH6
positive regulation of cardiac muscle cell proliferation (GO:0060045) -6.780.036NOTCH1, TBX5
heart valve morphogenesis (GO:0003179) -6.550.004NOTCH1, TBX5
cell migration involved in heart development (GO:0060973) -7.090.0NOTCH1, TBX5, MYH6
regulation of muscle cell differentiation (GO:0051147) NEW4.680.01NOTCH1, TBX5, MYH6
regulation of cardiac muscle cell proliferation (GO:0060043) -6.330.006NOTCH1, TBX5
positive regulation of muscle cell differentiation (GO:0051149) NEW5.260.001NOTCH1, TBX5, MYH6
regulation of stem cell differentiation (GO:2000736) -6.260.048NOTCH1, TBX5
canonical Wnt signaling pathway (GO:0060070) NEW5.260.002NOTCH1, TBX5, MYH6
cardiac chamber formation (GO:0003207) -7.330.001NOTCH1, TBX5, MYH6
cardiac chamber morphogenesis (GO:0003206) NEW6.360.0NOTCH1, TBX5, MYH6
growth involved in heart morphogenesis (GO:0003241) NEW8.340.0NOTCH1, MYH6
regulation of growth (GO:0040008) -3.260.018NOTCH1, TBX5, MYH6
cell fate determination (GO:0001709) NEW5.970.001NOTCH1, TBX5, MYH6
cardiac ventricle morphogenesis (GO:0003208) NEW6.550.04NOTCH1, TBX5
heart looping (GO:0001947) NEW5.650.001NOTCH1, TBX5, MYH6
regulation of organ growth (GO:0046620) -5.410.004NOTCH1, TBX5, MYH6
regulation of epithelial cell differentiation (GO:0030856) NEW4.960.015NOTCH1, TBX5, MYH6
tissue morphogenesis (GO:0048729) -3.870.005NOTCH1, TBX5, MYH6
epithelial tube morphogenesis (GO:0060562) NEW5.120.006NOTCH1, TBX5, MYH6
anatomical structure formation involved in morphogenesis (GO:0048646) -3.010.038NOTCH1, TBX5, MYH6
regulation of organ morphogenesis (GO:2000027) -4.220.029NOTCH1, TBX5, MYH6
muscle cell development (GO:0055001) -5.290.032NOTCH1, MYH6
regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) NEW4.390.036NOTCH1, TBX5, MYH6
tube morphogenesis (GO:0035239) NEW4.350.01NOTCH1, TBX5, MYH6
cardiac cell development (GO:0055006) -6.330.006NOTCH1, MYH6
embryonic heart tube morphogenesis (GO:0003143) NEW5.570.002NOTCH1, TBX5, MYH6
cardiac muscle tissue morphogenesis (GO:0055008) -5.80.001NOTCH1, TBX5, MYH6
atrial cardiac muscle tissue morphogenesis (GO:0055009) NEW8.120.003NOTCH1, MYH6
regulation of cardiac muscle tissue development (GO:0055024) -5.860.015NOTCH1, TBX5
cardiocyte differentiation (GO:0035051) -6.020.009NOTCH1, TBX5
regulation of cardiac muscle tissue growth (GO:0055021) -6.120.008NOTCH1, TBX5
regulation of striated muscle cell differentiation (GO:0051153) NEW5.260.003NOTCH1, TBX5, MYH6
embryonic appendage morphogenesis (GO:0035113) -5.240.004NOTCH1, TBX5, MYH6
heart development (GO:0007507) -4.240.0NOTCH1, TBX5, MYH6
cardiac ventricle formation (GO:0003211) -7.430.001NOTCH1, TBX5, MYH6
regulation of epithelial to mesenchymal transition (GO:0010717) -5.550.016NOTCH1, TBX5
striated muscle tissue development (GO:0014706) -5.230.041NOTCH1, TBX5
cardiac muscle tissue development (GO:0048738) -6.330.003NOTCH1, TBX5, MYH6
muscle tissue morphogenesis (GO:0060415) -5.620.001NOTCH1, TBX5, MYH6
atrioventricular valve morphogenesis (GO:0003181) -7.240.0NOTCH1, TBX5
cardiac septum morphogenesis (GO:0060411) -5.90.011NOTCH1, TBX5
heart valve formation (GO:0003188) NEW7.330.003NOTCH1, TBX5
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
cytoplasm (GO:0005737) 1.013NOTCH1, TBX5, MYH6
cell part (GO:0044464) 0.113NOTCH1, TBX5, MYH6
intracellular organelle part (GO:0044446) 0.813NOTCH1, TBX5, MYH6
intracellular organelle (GO:0043229) 0.513NOTCH1, TBX5, MYH6
intracellular part (GO:0044424) 0.283NOTCH1, TBX5, MYH6
organelle (GO:0043226) 0.43NOTCH1, TBX5, MYH6
organelle part (GO:0044422) 0.793NOTCH1, TBX5, MYH6
protein complex (GO:0043234) 1.512NOTCH1, MYH6
macromolecular complex (GO:0032991) 1.352NOTCH1, MYH6
intracellular membrane-bounded organelle (GO:0043231) 0.62NOTCH1, TBX5
nucleus (GO:0005634) 1.072NOTCH1, TBX5
nucleoplasm (GO:0005654) 1.892NOTCH1, TBX5
cytoplasmic part (GO:0044444) 0.822NOTCH1, MYH6
nuclear part (GO:0044428) 1.552NOTCH1, TBX5
membrane-bounded organelle (GO:0043227) 0.472NOTCH1, TBX5
cytosol (GO:0005829) 1.682NOTCH1, MYH6