Gene-disease associations table

GeneAssociated with TREMOR, HEREDITARY ESSENTIAL inLink to HGNCCytogenetic bandNumber of associated diseasesAssociated diseases
TENM4ClinVar, OMIMHGNC link11q14.11PS190300
DRD3OMIMHGNC link3q13.312PS190300, 181500
FUSClinVar, OMIM, HUMSAVARHGNC link16p11.22PS190300, PS105400

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD
Cytogenetic band analysis
Transcription Factors (TF) annotation from TRRUST
TFassociated to this disease# regulated genesRegulated genes# regulated genes associated with this diseaseRegulated genes associated with this disease
regulated geneassociated to this disease# TFsTFs # TFs associated with this diseaseTFs associated with this disease
Interactions from BIOGRID - physical
Gene1Gene2Direct InteractionNumber of shared interactorsShared genes in interaction

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic
Interactions from STRING
Interactions from CORUM
Interactions from CENSUS
Interactions from PDB
Interactions from manually curated literature
KEGG pathways annotation: shared terms / NET-GE enrichment (no shared terms)
REACTOME pathways annotation: shared terms / NET-GE enrichment (no shared terms)
GO - molecular function annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
binding (GO:0005488) 0.183FUS, DRD3, TENM4
protein binding (GO:0005515) 0.463FUS, DRD3, TENM4
organic cyclic compound binding (GO:0097159) 1.052FUS, DRD3
receptor binding (GO:0005102) 2.432FUS, DRD3
identical protein binding (GO:0042802) 2.632FUS, TENM4
GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GOICNumber of genes with the same GOGenes
cellular process (GO:0009987) 0.263FUS, DRD3, TENM4
regulation of cellular process (GO:0050794) 0.53FUS, DRD3, TENM4
organic substance metabolic process (GO:0071704) 0.633FUS, DRD3, TENM4
biological regulation (GO:0065007) 0.393FUS, DRD3, TENM4
metabolic process (GO:0008152) 0.583FUS, DRD3, TENM4
macromolecule metabolic process (GO:0043170) 0.833FUS, DRD3, TENM4
regulation of biological process (GO:0050789) 0.453FUS, DRD3, TENM4
regulation of primary metabolic process (GO:0080090) 1.082FUS, DRD3
regulation of metabolic process (GO:0019222) 1.022FUS, DRD3
regulation of cellular biosynthetic process (GO:0031326) 1.382FUS, DRD3
regulation of cellular metabolic process (GO:0031323) 1.072FUS, DRD3
nitrogen compound metabolic process (GO:0006807) 1.132FUS, DRD3
signal transduction (GO:0007165) 1.282DRD3, TENM4
single-organism process (GO:0044699) 0.482DRD3, TENM4
regulation of oligodendrocyte differentiation (GO:0048713) 6.362DRD3, TENM4
regulation of neurogenesis (GO:0050767) 3.212DRD3, TENM4
regulation of system process (GO:0044057) 3.532DRD3, TENM4
regulation of gliogenesis (GO:0014013) 5.212DRD3, TENM4
positive regulation of multicellular organismal process (GO:0051240) 2.492DRD3, TENM4
regulation of cell development (GO:0060284) 3.012DRD3, TENM4
regulation of developmental process (GO:0050793) 2.12DRD3, TENM4
regulation of glial cell differentiation (GO:0045685) 5.632DRD3, TENM4
regulation of macromolecule biosynthetic process (GO:0010556) 1.432FUS, DRD3
organic cyclic compound metabolic process (GO:1901360) 1.262FUS, DRD3
positive regulation of biological process (GO:0048518) 1.22DRD3, TENM4
multicellular organismal process (GO:0032501) 1.452DRD3, TENM4
regulation of nucleobase-containing compound metabolic process (GO:0019219) 1.432FUS, DRD3
cellular aromatic compound metabolic process (GO:0006725) 1.32FUS, DRD3
regulation of biosynthetic process (GO:0009889) 1.372FUS, DRD3
regulation of nucleic acid-templated transcription (GO:1903506) 1.552FUS, DRD3
regulation of cell differentiation (GO:0045595) 2.422DRD3, TENM4
single-organism cellular process (GO:0044763) 0.652DRD3, TENM4
regulation of nitrogen compound metabolic process (GO:0051171) 1.362FUS, DRD3
regulation of multicellular organismal process (GO:0051239) 1.872DRD3, TENM4
regulation of RNA biosynthetic process (GO:2001141) 1.552FUS, DRD3
response to chemical (GO:0042221) 1.982FUS, DRD3
primary metabolic process (GO:0044238) 0.692FUS, TENM4
cellular macromolecule metabolic process (GO:0044260) 0.932FUS, DRD3
single-multicellular organism process (GO:0044707) 1.782DRD3, TENM4
regulation of macromolecule metabolic process (GO:0060255) 1.082FUS, DRD3
response to stimulus (GO:0050896) 1.222FUS, DRD3
regulation of RNA metabolic process (GO:0051252) 1.522FUS, DRD3
cellular metabolic process (GO:0044237) 0.692FUS, DRD3
regulation of nervous system development (GO:0051960) 3.12DRD3, TENM4
regulation of multicellular organismal development (GO:2000026) 2.312DRD3, TENM4
positive regulation of cellular process (GO:0048522) 1.32DRD3, TENM4

NET-GE enrichment

Term New enriched termICP valueGenes
regulation of oligodendrocyte differentiation (GO:0048713) -6.360.002DRD3, TENM4
regulation of glial cell differentiation (GO:0045685) -5.630.009DRD3, TENM4
regulation of gliogenesis (GO:0014013) -5.210.016DRD3, TENM4
GO - cellular component annotation: shared terms (no NET-GE enrichment)

Shared terms

GOICNumber of genes with the same GOGenes
intracellular membrane-bounded organelle (GO:0043231) 0.63FUS, DRD3, TENM4
cell part (GO:0044464) 0.113FUS, DRD3, TENM4
intracellular organelle (GO:0043229) 0.513FUS, DRD3, TENM4
intracellular part (GO:0044424) 0.283FUS, DRD3, TENM4
cell projection (GO:0042995) 2.473FUS, DRD3, TENM4
membrane-bounded organelle (GO:0043227) 0.473FUS, DRD3, TENM4
organelle (GO:0043226) 0.43FUS, DRD3, TENM4
cytoplasm (GO:0005737) 1.012FUS, TENM4
integral component of plasma membrane (GO:0005887) 2.572DRD3, TENM4
plasma membrane part (GO:0044459) 1.952DRD3, TENM4
integral component of membrane (GO:0016021) 1.142DRD3, TENM4
membrane (GO:0016020) 0.682DRD3, TENM4
neuron part (GO:0097458) 2.642FUS, TENM4
cytoplasmic part (GO:0044444) 0.822FUS, DRD3
neuron projection (GO:0043005) 3.122FUS, TENM4
membrane part (GO:0044425) 0.952DRD3, TENM4
intrinsic component of plasma membrane (GO:0031226) 2.532DRD3, TENM4
nucleus (GO:0005634) 1.072FUS, TENM4
intrinsic component of membrane (GO:0031224) 1.132DRD3, TENM4