Gene table of SETX : senataxin

Gene-disease associations table

Disease ID	Disease name	Source of annotation with SETX	OMIM link	Number of associated genes	genes
PS105400	AMYOTROPHIC LATERAL SCLEROSIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	27	CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX
606002	SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 1	ClinVar, OMIM, HUMSAVAR	link to OMIM	1	SETX

Download the gene annotation in CSV format

Annotation of the gene SETX

Associated genes in ENSEMBL

ENSG00000107290

Associated proteins - SwissProt Accession ID

Q7Z333

Associated PDB IDs

Cytogenetic Band

9q34.13

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
purine ribonucleoside triphosphate binding	GO:0035639	2.22
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
DNA helicase activity	GO:0003678	5.73
heterocyclic compound binding	GO:1901363	1.06
purine nucleoside binding	GO:0001883	2.22
nucleoside binding	GO:0001882	2.21
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
nucleotide binding	GO:0000166	1.96
nucleoside phosphate binding	GO:1901265	1.96
ribonucleoside binding	GO:0032549	2.22
purine nucleotide binding	GO:0017076	2.19
double-stranded DNA binding	GO:0003690	3.09
ATP binding	GO:0005524	2.43
hydrolase activity	GO:0016787	1.9
transcription termination site sequence-specific DNA binding	GO:0001147	9.05
regulatory region nucleic acid binding	GO:0001067	3.03
nucleoside-triphosphatase activity	GO:0017111	3.09
transcription termination site DNA binding	GO:0001160	9.05
helicase activity	GO:0004386	4.69
small molecule binding	GO:0036094	1.89
catalytic activity	GO:0003824	1.05
transcription regulatory region DNA binding	GO:0044212	3.03
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO:0016818	3.03
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
adenyl nucleotide binding	GO:0030554	2.4
carbohydrate derivative binding	GO:0097367	2.03
organic cyclic compound binding	GO:0097159	1.05
hydrolase activity, acting on acid anhydrides	GO:0016817	3.03
pyrophosphatase activity	GO:0016462	3.04
adenyl ribonucleotide binding	GO:0032559	2.41
identical protein binding	GO:0042802	2.63
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
purine ribonucleotide binding	GO:0032555	2.2
purine ribonucleoside binding	GO:0032550	2.22
ribonucleotide binding	GO:0032553	2.19