Disease ID | Disease name | Source of annotation with VAPB | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS105400 | AMYOTROPHIC LATERAL SCLEROSIS | ClinVar, OMIM, HUMSAVAR | link to OMIM | 27 | CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX |
182980 | SPINAL MUSCULAR ATROPHY, LATE-ONSET, FINKEL TYPE | OMIM, HUMSAVAR | link to OMIM | 1 | VAPB |
Download the gene annotation in CSV format
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism of lipids and lipoproteins | R-HSA-556833 | 3.79 |
Sphingolipid metabolism | R-HSA-428157 | 6.79 |
Metabolism | R-HSA-1430728 | 2.34 |
Sphingolipid de novo biosynthesis | R-HSA-1660661 | 7.98 |
GO term | GO ID | GO IC |
---|---|---|
tubulin binding | GO:0015631 | 4.1 |
cytoskeletal protein binding | GO:0008092 | 3.02 |
microtubule binding | GO:0008017 | 4.42 |
FFAT motif binding | GO:0033149 | 9.05 |
enzyme binding | GO:0019899 | 2.27 |
beta-tubulin binding | GO:0048487 | 6.13 |
identical protein binding | GO:0042802 | 2.63 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
protein dimerization activity | GO:0046983 | 2.72 |
protein heterodimerization activity | GO:0046982 | 3.64 |
protein domain specific binding | GO:0019904 | 3.32 |
protein homodimerization activity | GO:0042803 | 3.16 |