Gene table of TUBA4A : tubulin alpha 4a

Gene-disease associations table

Disease IDDisease nameSource of annotation with TUBA4AOMIM linkNumber of associated genesgenes
PS105400AMYOTROPHIC LATERAL SCLEROSISClinVar, OMIM, HUMSAVAR link to OMIM 27CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX

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Annotation of the gene TUBA4A

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Pathogenic Escherichia coli infectionhsa051306.99
Phagosomehsa041455.27
Gap junctionhsa045406.24
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Platelet degranulation R-HSA-1146086.68
Gap junction assemblyR-HSA-1908618.03
Loss of Nlp from mitotic centrosomesR-HSA-3802597.03
Immune SystemR-HSA-1682562.37
Signaling by Rho GTPasesR-HSA-1943154.43
Recycling pathway of L1R-HSA-4372397.62
Microtubule-dependent trafficking of connexons from Golgi to the plasma membraneR-HSA-1908409.28
Formation of tubulin folding intermediates by CCT/TriCR-HSA-3899608.66
Signaling by HedgehogR-HSA-53583515.79
Cell CycleR-HSA-16401703.89
Assembly of the primary ciliumR-HSA-56178335.44
Intraflagellar transportR-HSA-56209247.25
Developmental BiologyR-HSA-12667383.48
Platelet activation, signaling and aggregationR-HSA-760025.15
Recruitment of mitotic centrosome proteins and complexesR-HSA-3802706.68
Separation of Sister ChromatidsR-HSA-24678135.55
Resolution of Sister Chromatid CohesionR-HSA-25002576.18
Hedgehog 'off' stateR-HSA-56107876.19
Mitotic Metaphase and AnaphaseR-HSA-25553965.45
Organelle biogenesis and maintenanceR-HSA-18522414.63
Response to elevated platelet cytosolic Ca2+R-HSA-760056.59
Adaptive Immune SystemR-HSA-12802183.19
Cell Cycle, MitoticR-HSA-692784.16
Factors involved in megakaryocyte development and platelet productionR-HSA-9832315.88
Loss of proteins required for interphase microtubule organizationĀ from the centrosomeR-HSA-3802847.03
HemostasisR-HSA-1095823.98
G2/M TransitionR-HSA-692756.06
RHO GTPases Activate ForminsR-HSA-56632206.01
L1CAM interactionsR-HSA-3737606.19
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingR-HSA-3899588.23
Prefoldin mediated transfer of substrate to CCT/TriCR-HSA-3899578.28
Centrosome maturationR-HSA-3802876.68
Mitotic G2-G2/M phasesR-HSA-4532746.04
Metabolism of proteinsR-HSA-3924993.41
Membrane TraffickingR-HSA-1999915.26
M PhaseR-HSA-688864.87
Anchoring of the basal body to the plasma membraneR-HSA-56209126.51
Transport of connexons to the plasma membraneR-HSA-1908729.18
Translocation of GLUT4 to the plasma membraneR-HSA-14451486.77
Mitotic AnaphaseR-HSA-688825.46
Gap junction trafficking and regulationR-HSA-1578587.52
Post-chaperonin tubulin folding pathwayR-HSA-3899778.81
Chaperonin-mediated protein foldingR-HSA-3904667.4
Vesicle-mediated transportR-HSA-56536564.33
RHO GTPase EffectorsR-HSA-1952584.94
Protein foldingR-HSA-3912517.23
Regulation of PLK1 Activity at G2/M TransitionR-HSA-25659426.66
Recruitment of NuMA to mitotic centrosomesR-HSA-3803208.46
Mitotic PrometaphaseR-HSA-688776.08
RHO GTPases activate IQGAPsR-HSA-56264678.34
MHC class II antigen presentationR-HSA-21322956.01
Axon guidanceR-HSA-4224753.93
KinesinsR-HSA-9831897.7
Gap junction traffickingR-HSA-1908287.59
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
structural constituent of cytoskeletonGO:00052005.12
purine ribonucleoside triphosphate bindingGO:00356392.22
enzyme bindingGO:00198992.27
bindingGO:00054880.18
structural molecule activityGO:00051983.1
heterocyclic compound bindingGO:19013631.06
purine nucleoside bindingGO:00018832.22
nucleoside bindingGO:00018822.21
pyrophosphatase activityGO:00164623.04
nucleotide bindingGO:00001661.96
guanyl ribonucleotide bindingGO:00325613.73
nucleoside phosphate bindingGO:19012651.96
ribonucleoside bindingGO:00325492.22
purine nucleotide bindingGO:00170762.19
GTP bindingGO:00055253.78
hydrolase activityGO:00167871.9
GTPase activityGO:00039244.31
nucleoside-triphosphatase activityGO:00171113.09
small molecule bindingGO:00360941.89
catalytic activityGO:00038241.05
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydridesGO:00168183.03
carbohydrate derivative bindingGO:00973672.03
organic cyclic compound bindingGO:00971591.05
hydrolase activity, acting on acid anhydridesGO:00168173.03
guanyl nucleotide bindingGO:00190013.73
protein bindingGO:00055150.46
purine ribonucleotide bindingGO:00325552.2
purine ribonucleoside bindingGO:00325502.22
ribonucleotide bindingGO:00325532.19