Disease ID | Disease name | Source of annotation with SOD1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
PS105400 | AMYOTROPHIC LATERAL SCLEROSIS | ClinVar, OMIM, HUMSAVAR | link to OMIM | 27 | CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX |
Download the gene annotation in CSV format
KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Amyotrophic lateral sclerosis (ALS) | hsa05014 | 7.01 |
Huntington's disease | hsa05016 | 5.17 |
Prion diseases | hsa05020 | 7.48 |
Peroxisome | hsa04146 | 6.34 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Platelet degranulation | R-HSA-114608 | 6.68 |
Platelet activation, signaling and aggregation | R-HSA-76002 | 5.15 |
Cellular responses to stress | R-HSA-2262752 | 4.56 |
Response to elevated platelet cytosolic Ca2+ | R-HSA-76005 | 6.59 |
Detoxification of Reactive Oxygen Species | R-HSA-3299685 | 8.23 |
Hemostasis | R-HSA-109582 | 3.98 |
GO term | GO ID | GO IC |
---|---|---|
enzyme binding | GO:0019899 | 2.27 |
small GTPase binding | GO:0031267 | 4.13 |
GTPase binding | GO:0051020 | 4.05 |
protein phosphatase 2B binding | GO:0030346 | 7.54 |
binding | GO:0005488 | 0.18 |
oxidoreductase activity | GO:0016491 | 3.12 |
oxidoreductase activity, acting on superoxide radicals as acceptor | GO:0016721 | 8.13 |
transition metal ion binding | GO:0046914 | 2.48 |
chaperone binding | GO:0051087 | 5.34 |
ion binding | GO:0043167 | 1.36 |
metal ion binding | GO:0046872 | 1.41 |
identical protein binding | GO:0042802 | 2.63 |
protein homodimerization activity | GO:0042803 | 3.16 |
cation binding | GO:0043169 | 1.4 |
antioxidant activity | GO:0016209 | 5.49 |
Ras GTPase binding | GO:0017016 | 4.2 |
catalytic activity | GO:0003824 | 1.05 |
protein phosphatase binding | GO:0019903 | 4.93 |
phosphatase binding | GO:0019902 | 4.63 |
Rho GTPase binding | GO:0017048 | 5.36 |
superoxide dismutase activity | GO:0004784 | 8.13 |
copper ion binding | GO:0005507 | 5.71 |
Rac GTPase binding | GO:0048365 | 6.05 |
protein binding | GO:0005515 | 0.46 |
protein dimerization activity | GO:0046983 | 2.72 |
zinc ion binding | GO:0008270 | 2.66 |