Gene table of TARDBP : TAR DNA binding protein

Gene-disease associations table

Disease ID	Disease name	Source of annotation with TARDBP	OMIM link	Number of associated genes	genes
PS105400	AMYOTROPHIC LATERAL SCLEROSIS	ClinVar, OMIM, HUMSAVAR	link to OMIM	27	CHCHD10, FIG4, ERBB4, SQSTM1, ATXN2, UBQLN2, DCTN1, FUS, NEFH, PFN1, VAPB, MATR3, ALS2, TBK1, SPG11, TARDBP, TUBA4A, SIGMAR1, SOD1, CHMP2B, PRPH, ANG, VCP, OPTN, C9orf72, HNRNPA1, SETX

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
nucleic acid binding transcription factor activity	GO:0001071	2.65
protein binding	GO:0005515	0.46
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
poly(A) RNA binding	GO:0044822	2.69
heterocyclic compound binding	GO:1901363	1.06
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0003705	5.23
nucleotide binding	GO:0000166	1.96
small molecule binding	GO:0036094	1.89
identical protein binding	GO:0042802	2.63
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
RNA binding	GO:0003723	2.36
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	GO:0001205	6.48
double-stranded DNA binding	GO:0003690	3.09
mRNA 3'-UTR binding	GO:0003730	5.85
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
nucleoside phosphate binding	GO:1901265	1.96
mRNA binding	GO:0003729	4.68