Gene table of EIF4G1 : eukaryotic translation initiation factor 4 gamma 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with EIF4G1OMIM linkNumber of associated genesgenes
PS168600PARKINSON DISEASEClinVar, OMIM, HUMSAVAR link to OMIM 30ATP13A2, FGF20, VPS13C, DNAJC13, ATXN2, PINK1, CHCHD2, ADH1C, UCHL1, GIGYF2, SYNJ1, PODXL, HTRA2, LRRK2, TBP, PARK2, ATXN8OS, SNCAIP, GBA, SNCA, NR4A2, PLA2G6, GLUD2, PARK7, ATXN3, MAPT, DNAJC6, EIF4G1, FBXO7, VPS35

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Annotation of the gene EIF4G1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST
Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
RNA transporthsa030135.37
Viral myocarditishsa054166.45
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)R-HSA-24041924.85
Immune SystemR-HSA-1682562.37
Cytokine Signaling in Immune systemR-HSA-12802153.74
IGF1R signaling cascadeR-HSA-24289244.85
IRS-related events triggered by IGF1RR-HSA-24289284.85
IRS-mediated signallingR-HSA-1123994.87
Signaling by Insulin receptorR-HSA-747524.73
Deadenylation-dependent mRNA decayR-HSA-4299147.37
Insulin receptor signalling cascadeR-HSA-747514.85
Eukaryotic Translation InitiationR-HSA-726136.18
Translation initiation complex formationR-HSA-726497.2
Gene ExpressionR-HSA-741602.72
TranslationR-HSA-727665.8
L13a-mediated translational silencing of Ceruloplasmin expressionR-HSA-1568276.28
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43SR-HSA-726627.18
Interferon SignalingR-HSA-9135314.95
Ribosomal scanning and start codon recognitionR-HSA-727027.2
Regulation of mRNA stability by proteins that bind AU-rich elementsR-HSA-4505316.56
GTP hydrolysis and joining of the 60S ribosomal subunitR-HSA-727066.27
mTORC1-mediated signallingR-HSA-1662088.52
AUF1 (hnRNP D0) destabilizes mRNAR-HSA-4504087.23
Metabolism of proteinsR-HSA-3924993.41
Antiviral mechanism by IFN-stimulated genesR-HSA-11694106.83
ISG15 antiviral mechanismR-HSA-11694086.83
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)R-HSA-9759576.25
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)R-HSA-9759566.51
Deadenylation of mRNAR-HSA-4299478.46
mTOR signallingR-HSA-1651597.7
PI3K CascadeR-HSA-1097046.68
Cap-dependent Translation InitiationR-HSA-727376.18
PKB-mediated eventsR-HSA-1097037.66
Nonsense-Mediated Decay (NMD)R-HSA-9278026.25
Signal TransductionR-HSA-1625821.78
Associated GO terms for Molecular function
GO termGO IDGO IC
nucleic acid bindingGO:00036761.44
organic cyclic compound bindingGO:00971591.05
poly(A) RNA bindingGO:00448222.69
translation factor activity, RNA bindingGO:00081355.07
RNA bindingGO:00037232.36
protein bindingGO:00055150.46
eukaryotic initiation factor 4E bindingGO:00081907.44
translation initiation factor bindingGO:00313696.37
translation initiation factor activityGO:00037435.7
heterocyclic compound bindingGO:19013631.06
bindingGO:00054880.18