Gene table of PAX5 : paired box 5

Gene-disease associations table

Disease ID	Disease name	Source of annotation with PAX5	OMIM link	Number of associated genes	genes
615545	LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 3	ClinVar, OMIM	link to OMIM	1	PAX5
613065	LEUKEMIA, ACUTE LYMPHOBLASTIC	HUMSAVAR	link to OMIM	9	PAX5, BCR, BAX, FLT3, NBN, TAL2, TAL1, NUP214, TCF3

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Annotation of the gene PAX5

Associated genes in ENSEMBL

ENSG00000196092

Associated proteins - SwissProt Accession ID

Q02548

Associated PDB IDs

Cytogenetic Band

9p13.2

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

TP53

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Transcriptional misregulation in cancer	hsa05202	5.21

Associated REACTOME pathways

Associated GO terms for Molecular function

GO term	GO ID	GO IC
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001077	4.31
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
heterocyclic compound binding	GO:1901363	1.06
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
regulatory region nucleic acid binding	GO:0001067	3.03
transcription regulatory region DNA binding	GO:0044212	3.03
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001228	3.98
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
nucleic acid binding transcription factor activity	GO:0001071	2.65