Gene table of CCND1 : cyclin D1

Gene-disease associations table

Disease ID	Disease name	Source of annotation with CCND1	OMIM link	Number of associated genes	genes
193300	VON HIPPEL-LINDAU SYNDROME	OMIM	link to OMIM	2	VHL, CCND1
254500	MYELOMA, MULTIPLE	OMIM	link to OMIM	2	LIG4, CCND1
114500	COLORECTAL CANCER	OMIM	link to OMIM	30	TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B

Associated genes in ENSEMBL

Associated proteins - SwissProt Accession ID

Associated PDB IDs

Cytogenetic Band

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Melanoma	hsa05218	6.56
Bladder cancer	hsa05219	7.38
FoxO signaling pathway	hsa04068	5.63
Pancreatic cancer	hsa05212	6.56
Endometrial cancer	hsa05213	6.81
Colorectal cancer	hsa05210	6.52
Thyroid cancer	hsa05216	7.48
Glioma	hsa05214	6.66
Jak-STAT signaling pathway	hsa04630	5.44
Focal adhesion	hsa04510	4.92
Oxytocin signaling pathway	hsa04921	5.4
Viral myocarditis	hsa05416	6.45
HTLV-I infection	hsa05166	4.59
Wnt signaling pathway	hsa04310	5.49
Hepatitis B	hsa05161	5.52
Measles	hsa05162	5.6
Proteoglycans in cancer	hsa05205	5.02
Cell cycle	hsa04110	5.68
MicroRNAs in cancer	hsa05206	5.38
Pathways in cancer	hsa05200	3.98
Viral carcinogenesis	hsa05203	5.08
p53 signaling pathway	hsa04115	6.56
Hippo signaling pathway	hsa04390	5.37
Prolactin signaling pathway	hsa04917	6.6
Acute myeloid leukemia	hsa05221	6.74
Chronic myeloid leukemia	hsa05220	6.48
Thyroid hormone signaling pathway	hsa04919	5.82
AMPK signaling pathway	hsa04152	5.8
PI3K-Akt signaling pathway	hsa04151	4.21
Prostate cancer	hsa05215	6.11
Non-small cell lung cancer	hsa05223	6.88
Small cell lung cancer	hsa05222	6.17

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Mitotic G1-G1/S phases	R-HSA-453279	5.91
G1 Phase	R-HSA-69236	7.73
Pre-NOTCH Transcription and Translation	R-HSA-1912408	8.12
Signaling by NOTCH	R-HSA-157118	6.2
S Phase	R-HSA-69242	6.02
RMTs methylate histone arginines	R-HSA-3214858	7.49
Cell Cycle, Mitotic	R-HSA-69278	4.16
Chromatin organization	R-HSA-4839726	5.19
Cyclin D associated events in G1	R-HSA-69231	7.73
Ubiquitin-dependent degradation of Cyclin D	R-HSA-75815	7.34
Cell Cycle	R-HSA-1640170	3.89
Pre-NOTCH Expression and Processing	R-HSA-1912422	7.49
Ubiquitin-dependent degradation of Cyclin D1	R-HSA-69229	7.34
Signal Transduction	R-HSA-162582	1.78
Chromatin modifying enzymes	R-HSA-3247509	5.19

Associated GO terms for Molecular function

GO term	GO ID	GO IC
kinase regulator activity	GO:0019207	4.5
enzyme binding	GO:0019899	2.27
macromolecular complex binding	GO:0044877	2.61
binding	GO:0005488	0.18
molecular function regulator	GO:0098772	2.51
proline-rich region binding	GO:0070064	6.79
transcription corepressor activity	GO:0003714	4.33
transcription cofactor activity	GO:0003712	3.44
cyclin-dependent protein serine/threonine kinase regulator activity	GO:0016538	6.41
transferase activity	GO:0016740	1.95
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
protein complex binding	GO:0032403	3.09
protein kinase activity	GO:0004672	3.27
histone deacetylase binding	GO:0042826	5.08
transcription factor binding	GO:0008134	3.46
protein kinase regulator activity	GO:0019887	4.6
enzyme regulator activity	GO:0030234	2.85
kinase activity	GO:0016301	2.93
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
catalytic activity	GO:0003824	1.05
phosphotransferase activity, alcohol group as acceptor	GO:0016773	3.08
transferase activity, transferring phosphorus-containing groups	GO:0016772	2.77
protein binding	GO:0005515	0.46