Gene table of TCF3 : transcription factor 3

Gene-disease associations table

Disease ID	Disease name	Source of annotation with TCF3	OMIM link	Number of associated genes	genes
613065	LEUKEMIA, ACUTE LYMPHOBLASTIC	OMIM	link to OMIM	9	PAX5, BCR, BAX, FLT3, NBN, TAL2, TAL1, NUP214, TCF3

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Annotation of the gene TCF3

Associated genes in ENSEMBL

ENSG00000071564

Associated proteins - SwissProt Accession ID

P15923

Associated PDB IDs

Cytogenetic Band

19p13.3

Tandem repeats annotation

Transcription regulation as annotated in TRRUST

It is a TF of the genes:

It is regulated by the following TF:

Associated KEGG pathways

KEGG pathway	KEGG ID	KEGG IC
Signaling pathways regulating pluripotency of stem cells	hsa04550	5.6
HTLV-I infection	hsa05166	4.59
Transcriptional misregulation in cancer	hsa05202	5.21

Associated REACTOME pathways

REACTOME pathway	REACTOME ID	REACTOME IC
Myogenesis	R-HSA-525793	8.12
Developmental Biology	R-HSA-1266738	3.48
CDO in myogenesis	R-HSA-375170	8.12

Associated GO terms for Molecular function

GO term	GO ID	GO IC
enzyme binding	GO:0019899	2.27
RNA polymerase II regulatory region DNA binding	GO:0001012	3.36
core promoter proximal region DNA binding	GO:0001159	3.82
binding	GO:0005488	0.18
nucleic acid binding	GO:0003676	1.44
DNA binding	GO:0003677	1.92
bHLH transcription factor binding	GO:0043425	6.41
E-box binding	GO:0070888	6.21
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0001078	5.08
heterocyclic compound binding	GO:1901363	1.06
repressing transcription factor binding	GO:0070491	5.71
sequence-specific DNA binding	GO:0043565	2.79
sequence-specific double-stranded DNA binding	GO:1990837	3.2
mitogen-activated protein kinase kinase kinase binding	GO:0031435	6.85
transcription coactivator activity	GO:0003713	4.04
transcription cofactor activity	GO:0003712	3.44
vitamin D response element binding	GO:0070644	8.64
identical protein binding	GO:0042802	2.63
transcription factor activity, transcription factor binding	GO:0000989	3.36
transcription factor activity, protein binding	GO:0000988	3.35
core promoter proximal region sequence-specific DNA binding	GO:0000987	3.83
double-stranded DNA binding	GO:0003690	3.09
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	GO:0000982	3.94
RNA polymerase II transcription factor activity, sequence-specific DNA binding	GO:0000981	3.29
protein homodimerization activity	GO:0042803	3.16
transcription factor binding	GO:0008134	3.46
regulatory region nucleic acid binding	GO:0001067	3.03
protein kinase binding	GO:0019901	3.44
kinase binding	GO:0019900	3.32
enhancer binding	GO:0035326	5.21
RNA polymerase II core promoter proximal region sequence-specific DNA binding	GO:0000978	3.88
transcription regulatory region DNA binding	GO:0044212	3.03
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	GO:0001227	4.61
transcription factor activity, sequence-specific DNA binding	GO:0003700	2.65
organic cyclic compound binding	GO:0097159	1.05
transcription regulatory region sequence-specific DNA binding	GO:0000976	3.24
RNA polymerase II regulatory region sequence-specific DNA binding	GO:0000977	3.37
protein binding	GO:0005515	0.46
regulatory region DNA binding	GO:0000975	3.03
protein dimerization activity	GO:0046983	2.72
protein heterodimerization activity	GO:0046982	3.64
nucleic acid binding transcription factor activity	GO:0001071	2.65