Disease table of MENTAL RETARDATION, AUTOSOMAL DOMINANT OMIM ID: PS156200

Gene-disease associations table

Gene	Associated with MENTAL RETARDATION, AUTOSOMAL DOMINANT in	Link to HGNC	Cytogenetic band	Number of associated diseases	Associated diseases
EPB41L1	ClinVar, OMIM, HUMSAVAR	HGNC link	20q11.23	1	PS156200
CDH15	ClinVar, OMIM, HUMSAVAR	HGNC link	16q24.3	1	PS156200
ADNP	ClinVar, OMIM	HGNC link	20q13.13	1	PS156200
PPP2R1A	ClinVar, OMIM, HUMSAVAR	HGNC link	19q13.41	1	PS156200
EEF1A2	ClinVar, OMIM, HUMSAVAR	HGNC link	20q13.33	2	PS156200, PS308350
CTNNB1	ClinVar, OMIM, HUMSAVAR	HGNC link	3p22.1	6	114550, 155255, 167000, PS156200, 114500, 132600
SETBP1	ClinVar, OMIM	HGNC link	18q12.3	6	601626, 614286, 608232, 269150, PS156200, 607785
ZMYND11	ClinVar, OMIM	HGNC link	10p15.3	1	PS156200
SMARCB1	ClinVar, OMIM, HUMSAVAR	HGNC link	22q11.23	4	PS156200, PS609322, PS135900, PS162091
SMARCA4	ClinVar, OMIM, HUMSAVAR	HGNC link	19p13.2	3	PS156200, PS135900, PS609322
EHMT1	ClinVar, OMIM, HUMSAVAR	HGNC link	9q34.3	1	PS156200
MEF2C	ClinVar, OMIM	HGNC link	5q14.3	1	PS156200
KANSL1	ClinVar, OMIM	HGNC link	17q21.31	1	PS156200
NR1I3	ClinVar	HGNC link	1q23.3	1	PS156200
SOX11	ClinVar, OMIM, HUMSAVAR	HGNC link	2p25.2	1	PS156200
ZBTB18	ClinVar, OMIM	HGNC link	1q44	1	PS156200
DEAF1	ClinVar, OMIM, HUMSAVAR	HGNC link	11p15.5	1	PS156200
MYT1L	ClinVar, OMIM	HGNC link	2p25.3	1	PS156200
AHDC1	OMIM	HGNC link	1p35.3	1	PS156200
KAT6A	ClinVar, OMIM	HGNC link	8p11.21	1	PS156200
DYRK1A	ClinVar, OMIM	HGNC link	21q22.13	1	PS156200
GRIN1	ClinVar, OMIM, HUMSAVAR	HGNC link	9q34.3	1	PS156200
DPP6	ClinVar, OMIM, HUMSAVAR	HGNC link	7q36.2	2	PS156200, 612956
KMT2C	ClinVar	HGNC link	7q36.1	1	PS156200
COL4A3BP	ClinVar, OMIM, HUMSAVAR	HGNC link	5q13.3	1	PS156200
SYNGAP1	ClinVar, OMIM, HUMSAVAR	HGNC link	6p21.32	1	PS156200
GATAD2B	ClinVar, OMIM	HGNC link	1q21.3	1	PS156200
DYNC1H1	ClinVar, OMIM, HUMSAVAR	HGNC link	14q32.31	3	PS118220, PS158600, PS156200
KIRREL3	ClinVar, OMIM, HUMSAVAR	HGNC link	11q24.2	1	PS156200
AUTS2	ClinVar, OMIM	HGNC link	7q11.22	1	PS156200
SETD5	ClinVar, OMIM	HGNC link	3p25.3	1	PS156200
PACS1	ClinVar, OMIM, HUMSAVAR	HGNC link	11q13.1	1	PS156200
KIF1A	ClinVar, OMIM, HUMSAVAR	HGNC link	2q37.3	3	PS156200, PS303350, PS162400
CHAMP1	ClinVar, OMIM	HGNC link	13q34	1	PS156200
GRIN2B	ClinVar, OMIM, HUMSAVAR	HGNC link	12p13.1	2	PS156200, PS308350
ARID1B	ClinVar, OMIM	HGNC link	6q25.3	2	PS156200, PS135900
ARID1A	ClinVar, OMIM	HGNC link	1p36.11	2	PS156200, PS135900
MBD5	ClinVar, OMIM	HGNC link	2q23.1	1	PS156200
PURA	ClinVar, OMIM, HUMSAVAR	HGNC link	5q31.3	1	PS156200
POGZ	ClinVar, OMIM	HGNC link	1q21.3	1	PS156200
PPP2R5D	ClinVar, OMIM, HUMSAVAR	HGNC link	6p21.1	1	PS156200
CACNG2	ClinVar, OMIM, HUMSAVAR	HGNC link	22q12.3	1	PS156200
CTCF	ClinVar, OMIM, HUMSAVAR	HGNC link	16q22.1	1	PS156200
SMARCE1	ClinVar	HGNC link	17q21.2	3	607174, PS135900, PS156200

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD

Cytogenetic band analysis

By sub-band

Shared sub_band	Number of genes associated with the disease	Genes associated with the disease
1q21.3	2	POGZ, GATAD2B
9q34.3	2	EHMT1, GRIN1

By band

Shared band	Number of genes associated with the disease	Genes associated with the disease
9q34	2	EHMT1, GRIN1
2p25	2	MYT1L, SOX11
20q13	2	EEF1A2, ADNP
1q21	2	POGZ, GATAD2B
17q21	2	KANSL1, SMARCE1
7q36	2	DPP6, KMT2C
6p21	2	PPP2R5D, SYNGAP1

By region

Shared region	Number of genes associated with the disease	Genes associated with the disease
2p2	2	MYT1L, SOX11
3p2	2	CTNNB1, SETD5
7q3	2	DPP6, KMT2C
1p3	2	AHDC1, ARID1A
22q1	2	SMARCB1, CACNG2
5q1	2	MEF2C, COL4A3BP
6p2	2	PPP2R5D, SYNGAP1
1q2	3	NR1I3, POGZ, GATAD2B
17q2	2	KANSL1, SMARCE1
16q2	2	CTCF, CDH15
20q1	3	EPB41L1, EEF1A2, ADNP
9q3	2	EHMT1, GRIN1

By arm

Shared arm	Number of genes associated with the disease	Genes associated with the disease
20q	3	EPB41L1, EEF1A2, ADNP
7q	3	DPP6, KMT2C, AUTS2
9q	2	EHMT1, GRIN1
16q	2	CTCF, CDH15
22q	2	SMARCB1, CACNG2
1q	4	NR1I3, ZBTB18, GATAD2B, POGZ
1p	2	AHDC1, ARID1A
3p	2	CTNNB1, SETD5
5q	3	MEF2C, COL4A3BP, PURA
6p	2	PPP2R5D, SYNGAP1
11q	2	PACS1, KIRREL3
17q	2	KANSL1, SMARCE1
2p	2	MYT1L, SOX11
2q	2	MBD5, KIF1A

By chromosome

Shared chromosome	Number of genes associated with the disease	Genes associated with the disease
11	3	DEAF1, PACS1, KIRREL3
20	3	EPB41L1, EEF1A2, ADNP
17	2	KANSL1, SMARCE1
22	2	SMARCB1, CACNG2
16	2	CTCF, CDH15
19	2	SMARCA4, PPP2R1A
1	6	POGZ, AHDC1, ARID1A, ZBTB18, NR1I3, GATAD2B
3	2	CTNNB1, SETD5
2	4	MYT1L, MBD5, SOX11, KIF1A
5	3	MEF2C, COL4A3BP, PURA
7	3	DPP6, KMT2C, AUTS2
6	3	ARID1B, PPP2R5D, SYNGAP1
9	2	EHMT1, GRIN1

Transcription Factors (TF) annotation from TRRUST

TF	associated to this disease	# regulated genes	Regulated genes	# regulated genes associated with this disease	Regulated genes associated with this disease
CTNNB1	YES	20	PTGS2, BIRC5, PPARD, CHGA, TCF7, CLDN2, CCND1, GLCE, CD44, GLI2, NRCAM, RB1, MMP14, JUN, SPP1, VIM, MYC, PLD1, MMP7, STARD7	0
SETBP1	YES	3	PTGS2, PTGER2, PPP2R4	0
ZMYND11	YES	1	IL6	0
SMARCB1	YES	2	CD44, CDKN2A	0
SMARCA4	YES	9	CDKN1A, CCND1, CDH1, CD44, CAD, MECOM, CDKN2A, FOS, ABCG2	0
MEF2C	YES	7	JUN, CPT1B, CALR, SOST, NR4A1, VEGFA, MAPK7	0
NR1I3	YES	4	UGT1A1, CYP2C9, CYP2B6, HNF4A	0
SOX11	YES	2	TUBB3, SPAST	0
DEAF1	YES	1	HTR1A	0
KAT6A	YES	1	HOXA9	0
ARID1B	YES	1	IGH	0
ARID1A	YES	3	IGH, CDKN1A, SMAD3	0
PURA	YES	4	FAS, ERBB2, AR, PCNA	0
CTCF	YES	19	MYC, CHD8, BCL6, IRAK2, BBC3, ATXN7, SLC6A4, MGAT5B, CSF2, RBL2, RARRES1, NF1, IGF2, TERT, PBXIP1, BRCA1, RAD21, PAX6, APP	0
NKX2-5	NO	9	DACT2, DACT1, GATA4, TBX5, DACT3, NPPB, CTNNB1, MEF2C, LYL1	2	MEF2C, CTNNB1
NFKB1	NO	306	NRF1, VWF, FTH1, PGLYRP2, CDK4, RGS4, IFNG, MMP2, DCST1, AGT, THBD, EGFR, GDNF, CCL4, NCAM1, VEGFA, CR2, CFI, TP53, FOXO3, CYP19A1, BGN, LPL, CXCL12, ELF3, PTHLH, HOXA9, IRF7, TNC, AGER, EDN1, HBEGF, SFTPA1, SAA1, TSLP, GSK3A, IFNB1, GKN2, TRAF2, PLA2G2A, F3, IL10, LIPE, FAF1, IL17A, CEACAM1, AKT1, KLK3, IL1RN, GSTP1, E2F1, CCR5, TAPBP, ADORA2A, CXCL1, PTPN6, MMP3, PIGR, ERAP1, YY1, OLFM4, DEFB4A, CCL2, CD28, SQSTM1, TERT, IL4, NAMPT, BACE1, JUNB, SLC9A2, FASLG, ALOX5, BCL2L1, CD83, TLR3, CCL22, PLIN1, CDKN1A, BIRC3, CSF2, CFLAR, TFPI2, MYB, IL18, SERPINB1, MUC17, TNFRSF10A, PTGFR, TFF3, PTAFR, PTGS2, COX1, SERPINA3, ITGAX, CCND2, MCL1, TLR7, POU2F2, REPS2, CD3G, TFF1, B2M, PLAU, TNF, FOXP3, HDAC7, MUC5B, CCR2, FIGF, HSD11B2, CCL13, IFNA1, NOX5, MAT2A, COL7A1, HMOX1, ADORA1, TNFSF10, AR, COL2A1, TAP1, IL1B, CD74, CD38, MUC5AC, MUC2, TIMP1, CCL19, FGF8, PDK4, CCL20, STK39, CYP3A7, MMP9, GATA3, IRF4, CD58, HES1, PLAUR, SP4, NFKB1, MMP1, NOX4, BDKRB1, CASP3, CYP1A1, PSMB9, PTEN, HPSE, CCNB1, CD40, NOS3, PTGDS, UPP1, HIF1A, TNFRSF9, CD80, TNFSF13B, IL23A, TNFAIP3, TNFSF14, IL12A, TRPC1, CYP2E1, OPRM1, HLA-F, AMH, XIAP, MADCAM1, HYAL1, A2M, CCL11, TBX21, ICAM1, BCL2L11, CHUK, TAP2, IL2RA, CTCF, ABCB1, GSK3B, CCND1, KLF5, CCR7, CCK, DCST2, MMP14, IL17C, FBP1, OPTN, IL1A, LTC4S, COL1A2, NOS1, WT1, BIRC5, PPIG, PTGES, CREB3, CXCL2, CRP, KDM2A, BCL2A1, BRCA2, IKBKB, GFAP, PSMB10, PROX1, COL1A1, TNIP3, NFKBIZ, TLR2, S100A6, DRD2, CXCL8, CD86, TRAF1, PTPN13, CSNK2A1, CARD8, CXCL10, IL6, CFTR, CASP9, ABCG2, BMP2, CRMP1, IL2, IRF1, SOD2, IER3, NFKBIA, FN1, SERPINE1, MICA, TBP, CXCR2, BHMT, NCOR1, SNAI1, BAX, NPPB, CTSB, F8, IL12B, IGF2BP1, LCN2, NOLC1, CD40LG, SELE, NOD2, CCL5, FAS, ALOX5AP, OLR1, CXCR4, SDC1, FLT4, NCOR2, AKT2, CDH1, TGFB1, CCL3, IGF2BP2, HDAC1, SP1, PDE7A, ADORA3, CRHR1, BCL3, MIF, CXCL5, TNFRSF10B, HAX1, CYP27B1, NLRP2, FGF7, PTGER4, TNFRSF13C, CARM1, EBI3, VCAM1, ERAP2, MYC, CSF1, EPCAM, SLC25A27, NOS2, RIPK2, EGR1, BTG2, BCL2, ABCA1, CD69, BIRC2, CCR3, IL21, GCLC, MMP13, GRIN1, SP3, RRM2B, STAT4, TF, MUC6	2	CTCF, GRIN1
REST	NO	29	SCG3, KCNN4, TPH2, NRP1, AVP, GLRA1, TUBB3, CACNA1H, OPRM1, CARTPT, SYN1, CHGA, GABRB3, CD59, GRIN2B, KCNQ3, TAC3, VGF, VIP, BDNF, LIN28A, CHGB, GJD2, PCSK1, PENK, TAC1, GRIN1, DYRK1A, KCNQ2	3	GRIN2B, GRIN1, DYRK1A

regulated gene	associated to this disease	# TFs	TFs	# TFs associated with this disease	TFs associated with this disease
CTNNB1	YES	8	AR, NKX2-5, LEF1, TP53, NELFCD, SOX6, ESR1, SIRT1	0
SMARCB1	YES	1	PARP1	0
MEF2C	YES	5	NKX2-5, GFI1B, GATA4, ISL1, HDAC7	0
NR1I3	YES	1	RARA	0
DYRK1A	YES	1	REST	0
GRIN1	YES	4	SP1, REST, NFKB1, RELA	0
GRIN2B	YES	2	HDAC1, REST	0
PURA	YES	1	IRF3	0
CTCF	YES	3	YY1, NFKB1, BCL3	0
PTGS2	NO	41	AR, ING4, TFAP2A, TCF7L2, CREB1, PGR, JUND, FOS, NFATC4, SP1, ETV4, STAT2, EGR1, STAT6, USF2, DR1, CTNNB1, HMGA1, PPARA, APC, EP300, HDAC1, STAT3, ATF2, JUN, RELA, HDAC4, SETBP1, NFKB1, STAT1, ELF3, NR0B2, CREBBP, NFIL3, CDX1, CEBPB, CEBPD, CDX2, JUNB, PPARG, USF1	2	SETBP1, CTNNB1
JUN	NO	29	AR, TNFAIP3, SMAD4, HDAC4, GLI2, ZNF382, RUNX1, NFRKB, ARNT, TCF4, MEF2D, CREB1, HDAC3, SMAD3, GLI1, WT1, NCOA2, ESR2, ATF2, JUN, NFIC, ABL1, PARP1, MEF2A, ZNF383, ESR1, MEF2C, CTNNB1, PITX1	2	MEF2C, CTNNB1
CDKN1A	NO	118	ABL1, TFAP4, TP53, MYF5, TCF3, HDAC9, PAX5, ZBTB2, LCOR, E2F3, ZBTB5, HSF1, ELL, TSC22D3, NCOA1, TAF1, RELA, MYOD1, STAT1, PTTG1, KLF16, ESR1, JUNB, MYCN, KAT2B, AR, BCL6, KLF10, EZH2, ARID1A, JUND, SP1, CEBPB, ZFHX3, ZNF300, EGR1, KLF4, AATF, HDAC7, HBP1, SMARCA4, ESR2, FOXP3, RARA, NELFCD, ING4, HDAC4, TBX2, IRF1, HDAC2, ETV6, SIRT2, MYOG, KLF6, TP73, SOX6, ATM, ERCC2, SMAD4, ETS2, NUPR1, PTMA, MLLT10, SMAD3, ETS1, CBX8, BRCA1, HIPK2, SIRT1, WT1, ZNF76, HDAC1, SMAD2, MLLT3, TFAP2A, EP300, FHL2, TP63, IRF9, EHMT2, TFAP2C, NFIX, RUNX3, RB1, HNF4A, NFIB, TAF5, SOX9, TBP, EAPP, ZBTB17, TAF4, REL, RELB, PML, SMAD7, NPM1, POU5F1, E2F1, TBX3, FOXG1, MYF6, NFIA, ATF2, PARP1, NFKB1, STAT3, GFI1, NR3C1, CREBBP, MTA1, JUN, KLF2, CDX2, SP3, MYC, PPARG, ING1	2	ARID1A, SMARCA4
CDKN2A	NO	24	FOXM1, EAPP, ETS2, EZH2, DNMT3A, HDAC9, ZBTB7A, SP1, HDAC3, MTA1, DNMT1, TBX2, E2F1, SMARCB1, TBX3, ZNF148, HDAC1, HDAC4, ETS1, SMARCA1, TBX5, SMARCA4, SP3, JUNB	2	SMARCB1, SMARCA4
CD44	NO	12	SP1, SMARCA1, TWIST2, SMARCA4, HDAC1, SNAI2, TWIST1, IKBKB, HMGA1, CTNNB1, SMARCB1, MYCN	3	SMARCB1, SMARCA4, CTNNB1
MYC	NO	66	E2F4, LEF1, PGR, FOXM1, TBP, FUBP1, TP53, MYBL2, SMAD4, MXI1, MYB, AATF, ZNF382, FOS, ZBTB7A, SP1, E2F5, RBL1, TCF4, TBL1X, EP300, SMAD7, HDAC3, TCF3, SRSF1, SMAD3, CNBP, TLX1, ESR1, SIRT1, WT1, APC, CTNNB1, CEBPE, PRDM1, IFI16, DLX5, HDAC10, ZNF300, JUN, ETS2, RELA, BCL6, NFKB1, BRCA1, E2F1, STAT3, HDAC11, CEBPA, HOXA1, PTTG1, PPARG, YY1, MTA1, HDAC2, NF1, SNIP1, RUNX3, RB1, CTCF, ENO1, BDP1, AHR, STAT4, RFX1, HNF4A	2	CTCF, CTNNB1
IGH	NO	3	ARID1A, POU2AF1, ARID1B	2	ARID1A, ARID1B
CCND1	NO	62	POU4F2, RELA, E2F4, MYBL2, AR, MECP2, PML, BHLHE41, EZH2, ATF2, PGR, JUND, FOS, PAX5, STAT5B, RUNX3, RNF14, POU2F1, EGR1, EP300, KLF4, HOXA1, STAT5A, CTNNB1, BRCA1, ESR1, SIRT1, VHL, SP1, KLF6, LEF1, HDAC1, KDM4B, NKX3-1, SOX2, HOXB7, JUN, ZNF24, TP53, NANOG, E2F8, NELFCD, NFKB1, E2F1, FHL2, STAT3, TCF4, BTG2, NR3C1, SP4, TSC22D3, SNIP1, HEXIM1, ING4, LIN28A, HIF1A, SMARCA4, SP3, MYC, PPARG, KLF5, SOX6	2	SMARCA4, CTNNB1

Interactions from BIOGRID - physical

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
EPB41L1	PPP2R1A	No	1	ELAVL1
EPB41L1	EEF1A2	No	3	COPS5, DGUOK, NUFIP1
EPB41L1	CTNNB1	No	4	COPS5, COPS3, ELAVL1, APP
EPB41L1	SETBP1	No	1	APP
EPB41L1	ZMYND11	No	1	ELAVL1
EPB41L1	SMARCB1	No	2	COPS5, APP
EPB41L1	SMARCA4	No	2	COPS5, HSPB1
EPB41L1	MEF2C	No	1	COPS5
EPB41L1	KANSL1	No	1	HSPB1
EPB41L1	ZBTB18	No	1	ELAVL1
EPB41L1	AHDC1	No	1	APP
EPB41L1	KAT6A	No	1	ELAVL1
EPB41L1	DYRK1A	No	2	ELAVL1, APP
EPB41L1	DPP6	No	2	DNAAF2, HAX1
EPB41L1	KMT2C	No	1	ELAVL1
EPB41L1	DYNC1H1	No	3	HTT, NUMA1, COPS5
EPB41L1	KIF1A	No	1	KIF5B
EPB41L1	ARID1A	No	1	ELAVL1
EPB41L1	POGZ	No	1	APP
EPB41L1	CACNG2	No	3	SRPK2, GRIA1, APP
CDH15	CTNNB1	No	2	BOC, CDON
ADNP	PPP2R1A	No	5	NTRK1, HDAC1, CCDC8, SIRT7, DYNLL1
ADNP	CTNNB1	No	8	EMD, HDAC1, CDC27, ILK, HDAC7, CCDC8, SMARCA4, NTRK1
ADNP	ZMYND11	No	3	HDAC1, HIST3H3, SAP18
ADNP	SMARCB1	No	9	SMARCA4, MAP1LC3B, EMD, HDAC1, NFATC1, SMARCC2, SAP18, ARID1A, MYC
ADNP	SMARCA4	Yes	14	MYC, CBX5, RNF2, EED, HDAC1, RBPJ, SMARCC2, SIRT7, FOXE1, NTRK1, ARID1A, NFATC1, BMI1, KPNA1
ADNP	EHMT1	No	7	CBX5, HIST3H3, EED, HDAC1, ZNF644, BMI1, CBX1
ADNP	MEF2C	No	1	HDAC7
ADNP	KANSL1	No	1	FOXK2
ADNP	AHDC1	No	3	CBX5, HIST3H3, CBX1
ADNP	KAT6A	No	1	HIST3H3
ADNP	DYRK1A	No	3	NTRK1, DYNLL1, CCDC8
ADNP	GATAD2B	No	10	FOXS1, RNF2, FOXG1, EED, HDAC1, KPNA1, NFATC1, FOXQ1, NTRK1, FOXJ2
ADNP	DYNC1H1	No	7	CCDC8, DYNLL1, RNF2, SIRT7, NTRK1, BMI1, MYC
ADNP	AUTS2	No	1	RNF2
ADNP	PACS1	No	1	NTRK1
ADNP	KIF1A	No	2	NTRK1, SIRT7
ADNP	CHAMP1	No	5	CBX1, ZNF644, HIST3H3, CBX5, CBX3
ADNP	ARID1B	No	4	SMARCA4, SMARCC2, QPRT, ARID1A
ADNP	ARID1A	Yes	4	EED, SMARCC2, SMARCA4, SIRT7
ADNP	PURA	No	2	NTRK1, BMI1
ADNP	POGZ	No	11	CBX5, HIST3H3, FOXG1, EED, SIRT7, USP37, RNF2, CBX3, CBX1, FOXQ1, FOXJ2
ADNP	PPP2R5D	No	1	NTRK1
ADNP	CTCF	No	3	EED, BMI1, SIRT7
ADNP	SMARCE1	No	5	SMARCA4, SMARCC2, RNF2, HDAC1, ARID1A
PPP2R1A	EEF1A2	No	10	VCP, MCM2, MAPK6, RPSA, CUL4A, UBC, EEF2, ESRRB, ARRB2, CUL3
PPP2R1A	CTNNB1	No	30	BTF3, LATS2, STRN3, OBSL1, CAV1, CUL4A, EGFR, HNRNPA1, CTNNBIP1, NHSL1, MCM2, RPSA, RBMX, ZFYVE9, SMAD3, FOXO3, SMURF1, HDAC1, ELAVL1, SMAD2, AKT1, HDAC4, PTPN14, NOTCH1, HSPA8, CTNNA2, CCDC8, ESR1, NTRK1, CUL3
PPP2R1A	SETBP1	No	2	SET, PPP2CA
PPP2R1A	ZMYND11	No	8	TRADD, SMAD2, HDAC1, PPP2CA, TP53, SMAD3, ELAVL1, TAB1
PPP2R1A	SMARCB1	No	4	HDAC1, CUL3, TP53, AKT1
PPP2R1A	SMARCA4	No	13	NOTCH1, CDC5L, HDAC1, SIRT7, OBSL1, TP53, SMAD3, SMAD2, ESR1, NPM1, NTRK1, CUL3, MARK4
PPP2R1A	EHMT1	No	2	HDAC1, TP53
PPP2R1A	MEF2C	No	3	HDAC4, HDAC5, SMAD2
PPP2R1A	KANSL1	No	3	PLEKHA5, SMAD3, CDC5L
PPP2R1A	NR1I3	No	1	HSP90AA1
PPP2R1A	ZBTB18	No	1	ELAVL1
PPP2R1A	DEAF1	No	1	AIMP2
PPP2R1A	MYT1L	No	1	CDC5L
PPP2R1A	KAT6A	No	4	ESR1, ELAVL1, TP53, AKT1
PPP2R1A	DYRK1A	No	7	CLTC, LATS2, DYNLL1, ELAVL1, SMAD3, CCDC8, NTRK1
PPP2R1A	KMT2C	No	1	ELAVL1
PPP2R1A	COL4A3BP	No	2	MARK2, PPP2R5C
PPP2R1A	GATAD2B	No	7	NOTCH1, HDAC1, SMAD2, ZNF219, NTRK1, PARK7, FOXC1
PPP2R1A	DYNC1H1	No	22	HSPA1A, CDC5L, STRN4, EGFR, STRN, DYNLL1, VCAM1, SIRT7, ARRB2, CSNK2B, FN1, ITGA4, OBSL1, LRRK2, SMAD2, HSP90AA1, PPP2R3C, CCDC8, CUL7, NTRK1, MCM2, CUL3
PPP2R1A	AUTS2	No	1	CSNK2B
PPP2R1A	PACS1	No	2	NTRK1, FGFR1OP
PPP2R1A	KIF1A	No	5	SPRY2, NTRK1, ESR1, EGFR, SIRT7
PPP2R1A	GRIN2B	No	1	GNB2L1
PPP2R1A	ARID1B	No	1	SMAD2
PPP2R1A	ARID1A	No	9	CDC5L, TP53, SIRT7, SMAD2, SMAD3, ELAVL1, ESR1, SNW1, CUL3
PPP2R1A	PURA	No	7	HNRNPA1, RPS8, UBC, RAF1, NTRK1, SNW1, CUL3
PPP2R1A	POGZ	No	1	SIRT7
PPP2R1A	PPP2R5D	Yes	21	PPP2R2D, LPP, PRDX2, RORC, PPP4C, PRDX1, SGOL1, PPP2R1B, PPP2R2A, PPP2R1A, CSNK2B, PPP2CA, PPME1, PPFIA1, PPP2CB, NTRK1, DNAAF5, PPP2R5A, CRY1, CHEK2, DEC1
PPP2R1A	CTCF	No	4	SMAD3, SET, SIRT7, NPM1
PPP2R1A	SMARCE1	No	3	HDAC1, CUL3, ESR1
EEF1A2	CTNNB1	No	10	PTEN, PARK2, MCM2, AURKA, CUL4A, RPSA, COPS5, ISG15, CUL1, CUL3
EEF1A2	ZMYND11	No	3	SRRM2, PABPC1, EFTUD2
EEF1A2	SMARCB1	No	4	POLR2A, COPS5, CUL3, CAND1
EEF1A2	SMARCA4	No	6	STK11, ACTB, CAND1, POLR2A, COPS5, CUL3
EEF1A2	MEF2C	No	1	COPS5
EEF1A2	DEAF1	No	1	CDC37
EEF1A2	DYRK1A	No	3	ID2, PARK2, ISG15
EEF1A2	DYNC1H1	No	7	CRY2, ARRB2, COPS5, CUL3, RPA2, MCM2, HEXIM1
EEF1A2	GRIN2B	No	1	PARK2
EEF1A2	ARID1B	No	2	CUL2, CAND1
EEF1A2	ARID1A	No	2	CUL2, CUL3
EEF1A2	PURA	No	5	UBC, CUL1, CUL3, CAND1, IGSF8
EEF1A2	PPP2R5D	No	2	RPA2, CRY2
EEF1A2	CTCF	No	2	POLR2A, CAND1
EEF1A2	SMARCE1	No	5	CAND1, CEP76, CUL3, ACTB, HAUS2
CTNNB1	SETBP1	No	1	APP
CTNNB1	ZMYND11	No	7	EP400, CDK2, HDAC1, SMAD2, EZH2, SMAD3, ELAVL1
CTNNB1	SMARCB1	No	20	KAT2B, KMT2A, CCNE1, SMARCA4, TBL1XR1, CREBBP, CUL3, NONO, HDAC1, EMD, RB1CC1, COPS5, XPO1, AKT1, EPAS1, CARM1, BRCA1, SOX2, TBL1X, APP
CTNNB1	SMARCA4	Yes	26	AR, BCL6, DDX5, NONO, SP1, CARM1, PML, CREB1, SMAD3, COPS5, BRCA1, NOTCH1, OBSL1, HDAC1, FANCA, SMAD2, EPAS1, CCNE1, RXRA, EP400, CUL3, ESR1, NTRK1, AHR, PPARG, HIF1A
CTNNB1	EHMT1	No	4	HDAC1, CTBP1, EZH2, BCL6
CTNNB1	MEF2C	No	10	SP1, EP300, SMAD2, HDAC4, HDAC7, COPS5, YWHAZ, EPAS1, IFRD1, SIRT1
CTNNB1	KANSL1	No	4	TRAF4, RBBP5, SMAD3, NUP62
CTNNB1	NR1I3	No	3	PML, RXRA, HNF4A
CTNNB1	ZBTB18	No	2	CTBP1, ELAVL1
CTNNB1	DEAF1	No	4	GSK3A, GSK3B, CREB1, PIN1
CTNNB1	AHDC1	No	1	APP
CTNNB1	KAT6A	No	7	KMT2A, ESR1, PML, ELAVL1, AKT1, EP300, CREBBP
CTNNB1	DYRK1A	No	16	CCDC8, LATS2, ISG15, EP300, PARK2, CREBBP, XPO1, ELAVL1, APP, SMAD3, MOV10, SFN, NTRK1, NXF1, CTBP1, CCNA2
CTNNB1	GRIN1	No	2	FYN, PRKCA
CTNNB1	KMT2C	No	4	ASH2L, RBBP5, CDC73, ELAVL1
CTNNB1	COL4A3BP	No	1	RANBP2
CTNNB1	GATAD2B	No	7	NOTCH1, HDAC1, SOX2, SMAD2, NTRK1, BRCA1, ZBTB33
CTNNB1	DYNC1H1	No	21	SERBP1, UNK, OBSL1, EGFR, CDK2, FUS, MCM2, CUL3, HDAC6, MAPRE1, SMAD2, CCDC8, NTRK1, FOXB1, COPS5, SIRT1, RUVBL2, RYK, BRCA1, DDX1, FBXW11
CTNNB1	AUTS2	No	1	EP300
CTNNB1	SETD5	No	1	NXF1
CTNNB1	PACS1	No	1	NTRK1
CTNNB1	KIF1A	No	7	SP1, AR, ESR1, EGFR, NTRK1, RXRA, PPARG
CTNNB1	CHAMP1	No	1	PIN1
CTNNB1	GRIN2B	No	4	ERBB2IP, FYN, PARK2, PRKCA
CTNNB1	ARID1B	No	3	EPAS1, SMAD2, SMARCA4
CTNNB1	ARID1A	No	11	UNK, CARM1, SMARCA4, SMAD2, SMAD3, ELAVL1, ESR1, NXF1, SOX2, CUL3, MOV10
CTNNB1	MBD5	No	1	APC
CTNNB1	PURA	No	6	SP1, HNRNPA1, CUL1, POU5F1, NTRK1, CUL3
CTNNB1	POGZ	No	8	SP1, CDK6, XPO1, CREB1, APP, NXF1, DAZAP2, MOV10
CTNNB1	PPP2R5D	No	4	NTRK1, GSK3B, PTPRF, SOX2
CTNNB1	CACNG2	No	1	APP
CTNNB1	CTCF	No	7	CHD8, SMAD3, LMNA, PARP1, TOP2A, RXRA, ZBTB33
CTNNB1	SMARCE1	No	14	AR, CARM1, NUP153, TCF4, NUP62, XPO1, RBBP5, NR4A1, CUL3, ESR1, NXF1, HDAC1, SMARCA4, MOV10
SETBP1	ZMYND11	No	1	UBE2I
SETBP1	SMARCB1	No	1	APP
SETBP1	MEF2C	No	1	UBE2I
SETBP1	AHDC1	No	1	APP
SETBP1	DYRK1A	No	1	APP
SETBP1	AUTS2	No	1	YAF2
SETBP1	POGZ	No	1	APP
SETBP1	PPP2R5D	No	1	PPP2CA
SETBP1	CACNG2	No	1	APP
SETBP1	CTCF	No	1	SET
ZMYND11	SMARCB1	No	5	SAP18, HDAC1, NCOR1, SMARCA2, TP53
ZMYND11	SMARCA4	No	7	SMARCA2, HDAC1, EP400, SMAD2, SMAD3, TP53, NCOR1
ZMYND11	EHMT1	No	5	HDAC1, H3F3A, HIST3H3, EZH2, TP53
ZMYND11	MEF2C	No	2	UBE2I, SMAD2
ZMYND11	KANSL1	No	2	SMAD3, TRAF2
ZMYND11	ZBTB18	No	1	ELAVL1
ZMYND11	AHDC1	No	1	HIST3H3
ZMYND11	KAT6A	No	4	ELAVL1, HIST3H3, RPL10, TP53
ZMYND11	DYRK1A	No	5	TRAF3, SRSF1, SRSF4, ELAVL1, SMAD3
ZMYND11	KMT2C	No	2	H3F3A, ELAVL1
ZMYND11	GATAD2B	No	3	HDAC1, TRAF1, SMAD2
ZMYND11	DYNC1H1	No	2	SMAD2, CDK2
ZMYND11	SETD5	No	1	TRAF2
ZMYND11	KIF1A	No	1	TRAF1
ZMYND11	CHAMP1	No	1	HIST3H3
ZMYND11	ARID1B	No	2	SMARCA2, SMAD2
ZMYND11	ARID1A	No	5	SMAD3, SMARCA2, SMAD2, ELAVL1, TP53
ZMYND11	POGZ	No	1	HIST3H3
ZMYND11	PPP2R5D	No	1	PPP2CA
ZMYND11	CTCF	No	1	SMAD3
ZMYND11	SMARCE1	No	3	HDAC1, SMARCA2, NCOR1
SMARCB1	SMARCA4	Yes	56	CHFR, KLF1, TP53, RPS6KA5, SS18, DPF2, SMARCAD1, TAT, HDAC1, ARID1A, NCOR1, SMARCD2, CARM1, DPF3, ARID1B, RUNX1, TOP2B, PBRM1, MCPH1, NONO, SMARCE1, CDK8, SMARCC2, COPS5, RELB, CDYL, BRCA1, ACTL6A, PHF10, SMARCD3, BCL7B, DPF1, HSF1, PRMT5, SMARCB1, SIN3A, BCL7C, NFATC1, GATA1, EPAS1, CCNE1, ARID2, SMARCD1, SMARCC1, SMARCA2, BCL7A, HDAC2, CAND1, CEBPB, POLR2A, SIN3B, CDX2, MYC, RBBP4, CUL3, ING1
SMARCB1	EHMT1	No	5	HDAC1, HDAC2, TP53, SMARCAD1, TFAP4
SMARCB1	MEF2C	No	2	EPAS1, COPS5
SMARCB1	DEAF1	No	2	PPP1CC, PPP1CA
SMARCB1	AHDC1	No	2	ZDHHC17, APP
SMARCB1	KAT6A	No	5	CREBBP, KMT2A, RUNX1, TP53, AKT1
SMARCB1	DYRK1A	No	3	CREBBP, APP, XPO1
SMARCB1	KMT2C	Yes	2	JUN, SMARCB1
SMARCB1	GATAD2B	No	7	HDAC1, HDAC2, NFATC1, SOX2, TAT, RBBP4, BRCA1
SMARCB1	DYNC1H1	No	5	COPS5, BRCA1, PRMT5, MYC, CUL3
SMARCB1	ARID1B	Yes	20	SMARCC1, SMARCD2, SMARCA2, SMARCD3, BCL7B, BCL7A, DPF3, SMARCD1, SMARCB1, PRMT5, BCL7C, DPF2, SMARCE1, SMARCC2, CAND1, SMARCA4, EPAS1, ARID1A, ACTL6A, SS18
SMARCB1	ARID1A	Yes	28	KLF1, TP53, ACTL6A, TAT, SMARCE1, CARM1, BCL7A, PBRM1, DPF2, SMARCD2, SMARCC2, SMARCD3, TFAP4, PHF10, BCL7B, ARID1B, SMARCB1, BCL7C, SOX2, GATA1, SMARCD1, SMARCC1, SMARCA2, DPF3, SS18, SMARCA4, CUL3, ING1
SMARCB1	PURA	No	2	CUL3, CAND1
SMARCB1	POGZ	No	2	APP, XPO1
SMARCB1	PPP2R5D	No	1	SOX2
SMARCB1	CACNG2	No	1	APP
SMARCB1	CTCF	No	5	CAND1, POLR2A, SIN3A, TFAP4, TOP2B
SMARCB1	SMARCE1	Yes	40	SMARCAD1, KLF1, XPO1, TFAP4, ACTL6A, ARID1A, HDAC1, ARID1B, NCOR1, CARM1, DPF3, TOP2B, PBRM1, DPF2, SMARCD2, SMARCC2, RELB, DPF1, SS18, PHF10, BCL7B, SMARCD3, FOXN1, PRMT5, SMARCB1, SIN3A, BCL7C, JUN, GATA1, MECP2, ARID2, SMARCD1, SMARCC1, SMARCA2, NR0B2, HDAC2, CAND1, CUL3, SMARCA4, SIN3B
SMARCA4	EHMT1	No	11	CBX5, MDM2, BCL6, EED, HDAC1, HDAC2, TP53, SMARCAD1, BMI1, HIST1H3A, GMNN
SMARCA4	MEF2C	No	7	SP1, SMAD2, MYOD1, COPS5, EPAS1, HDAC9, MYOG
SMARCA4	KANSL1	No	3	SMAD3, HSPB1, CDC5L
SMARCA4	NR1I3	No	3	PML, MED17, RXRA
SMARCA4	DEAF1	No	2	CDKN2A, CREB1
SMARCA4	MYT1L	No	1	CDC5L
SMARCA4	AHDC1	No	1	CBX5
SMARCA4	KAT6A	No	6	PML, TP53, HIST2H3C, ESR1, HIST1H3A, RUNX1
SMARCA4	DYRK1A	No	6	RBL1, RBL2, RB1, SMAD3, NTRK1, HIST1H3A
SMARCA4	KMT2C	No	4	KDM6A, HIST1H3A, SMARCB1, HIST2H3C
SMARCA4	GATAD2B	No	19	CHD4, NOTCH1, HIST2H2BE, RNF2, KPNA1, EED, HDAC1, HDAC2, MBD3, NFATC1, HIST1H3A, SMAD2, MTA2, NTRK1, BRCA1, HIST1H3E, RBBP4, TAT, ZMYND8
SMARCA4	DYNC1H1	No	12	MYC, OBSL1, RNF2, CDC5L, PRMT5, SMAD2, COPS5, SIRT7, NTRK1, BMI1, BRCA1, CUL3
SMARCA4	AUTS2	No	1	RNF2
SMARCA4	PACS1	No	1	NTRK1
SMARCA4	KIF1A	No	7	SP1, AR, SIRT7, ESR1, NTRK1, RXRA, PPARG
SMARCA4	CHAMP1	No	2	CBX5, MDC1
SMARCA4	ARID1B	Yes	22	ACTL6A, ARID1A, SMARCD2, HIST2H2BE, BCL7A, DPF2, SMARCE1, SMARCC2, SMARCD3, SMARCA1, BCL7B, SMARCB1, PRMT5, BCL7C, SMAD2, EPAS1, SMARCD1, SMARCC1, SMARCA2, DPF3, CAND1, SS18
SMARCA4	ARID1A	Yes	33	CDC5L, KLF1, TP53, DPF2, TAT, SMARCD2, ADNP, CARM1, BCL7A, PBRM1, SIRT7, SMARCE1, SMARCC2, SMAD3, SS18, SMARCD3, ACTL6A, PHF10, BCL7B, ARID1B, EED, SMARCB1, BCL7C, SMAD2, CHD7, GATA1, SMARCD1, SMARCC1, SMARCA2, DPF3, CUL3, ESR1, ING1
SMARCA4	PURA	No	6	SP1, CAND1, RB1, NTRK1, BMI1, CUL3
SMARCA4	POGZ	No	7	SP1, CBX5, RNF2, EED, SIRT7, CREB1, MDC1
SMARCA4	PPP2R5D	No	1	NTRK1
SMARCA4	CACNG2	No	1	STAT3
SMARCA4	CTCF	No	14	EED, SIN3A, SIRT7, CDK19, POLR2A, SMC3, KPNA2, CHD7, SMAD3, CAND1, NPM1, BMI1, RXRA, TOP2B
SMARCA4	SMARCE1	Yes	52	AR, SIN3B, MDM2, KLF1, WWOX, REST, SS18, BRD7, SMARCAD1, ARID1A, HDAC1, ARID1B, RELB, HIST1H3E, CARM1, DPF3, CAND1, TOP2B, PBRM1, SMARCC2, DPF2, SMARCD2, BCL7C, SS18L1, NCOR1, DPF1, SMARCB1, PHF10, BCL7B, SMARCD3, ACTL6A, SIN3A, CHD4, PRMT5, SMARCA2, RNF2, CHD7, GATA1, ZMIZ2, STAT2, ARID2, RCOR1, SMARCC1, HMGB1, NR3C1, SMARCD1, HDAC2, ACTB, UL29, CUL3, ESR1, IKZF1
EHMT1	ZBTB18	No	3	DNMT3A, CTBP1, CTBP2
EHMT1	AHDC1	No	4	ATXN1, CBX5, HIST3H3, CBX1
EHMT1	KAT6A	No	4	ATXN1, HIST1H3A, HIST3H3, TP53
EHMT1	DYRK1A	No	2	HIST1H3A, CTBP1
EHMT1	KMT2C	No	2	HIST1H3A, H3F3A
EHMT1	GATAD2B	No	5	EED, HDAC1, HDAC2, ZBTB46, HIST1H3A
EHMT1	DYNC1H1	No	1	BMI1
EHMT1	CHAMP1	No	5	CBX1, CBX5, HIST3H3, ZNF644, MAD2L2
EHMT1	ARID1A	No	3	EED, TFAP4, TP53
EHMT1	PURA	No	1	BMI1
EHMT1	POGZ	No	5	EED, CBX5, HIST3H3, CBX1, MAD2L2
EHMT1	CTCF	No	3	EED, BMI1, TFAP4
EHMT1	SMARCE1	No	5	HDAC1, HDAC2, MDM2, SMARCAD1, TFAP4
MEF2C	NR1I3	No	1	NCOA2
MEF2C	KAT6A	No	1	EP300
MEF2C	DYRK1A	No	1	EP300
MEF2C	KMT2C	No	1	MAPK14
MEF2C	GATAD2B	No	1	SMAD2
MEF2C	DYNC1H1	No	3	COPS5, SMAD2, SIRT1
MEF2C	AUTS2	No	1	EP300
MEF2C	KIF1A	No	1	SP1
MEF2C	ARID1B	No	2	EPAS1, SMAD2
MEF2C	ARID1A	No	1	SMAD2
MEF2C	PURA	No	1	SP1
MEF2C	POGZ	No	1	SP1
KANSL1	MYT1L	No	2	DISC1, CDC5L
KANSL1	KAT6A	No	1	WDR5
KANSL1	DYRK1A	No	1	SMAD3
KANSL1	KMT2C	No	2	WDR5, RBBP5
KANSL1	GATAD2B	No	6	GOLGA2, WDR5, CEP70, TRIM27, USHBP1, CALCOCO2
KANSL1	DYNC1H1	No	3	NINL, DISC1, CDC5L
KANSL1	AUTS2	No	1	WDR5
KANSL1	SETD5	No	3	CCDC85B, CEP70, TRAF2
KANSL1	KIF1A	No	2	TRIM27, MDFI
KANSL1	CHAMP1	No	1	KAT8
KANSL1	ARID1A	No	2	SMAD3, CDC5L
KANSL1	PPP2R5D	No	2	FSD2, USHBP1
KANSL1	CTCF	Yes	1	SMAD3
KANSL1	SMARCE1	No	12	GOLGA2, SPAG5, CCDC136, NUP62, KRT15, CDR2, RBBP5, CEP70, USHBP1, DISC1, KIFC3, TFIP11
NR1I3	KAT6A	No	1	PML
NR1I3	DYRK1A	No	1	MED23
NR1I3	DYNC1H1	No	1	HSP90AA1
NR1I3	KIF1A	No	2	MED1, RXRA
NR1I3	ARID1A	No	1	NCOA1
NR1I3	CTCF	No	1	RXRA
NR1I3	SMARCE1	No	2	MED4, NCOA1
ZBTB18	KAT6A	No	1	ELAVL1
ZBTB18	DYRK1A	No	2	CTBP1, ELAVL1
ZBTB18	KMT2C	No	1	ELAVL1
ZBTB18	ARID1A	No	1	ELAVL1
DEAF1	CHAMP1	No	1	PIN1
DEAF1	POGZ	No	1	CREB1
DEAF1	PPP2R5D	No	1	GSK3B
MYT1L	DYNC1H1	No	2	DISC1, CDC5L
MYT1L	ARID1A	No	1	CDC5L
MYT1L	SMARCE1	No	1	DISC1
AHDC1	KAT6A	No	2	ATXN1, HIST3H3
AHDC1	DYRK1A	No	1	APP
AHDC1	CHAMP1	No	3	CBX5, HIST3H3, CBX1
AHDC1	POGZ	No	4	CBX1, HIST3H3, CBX5, APP
AHDC1	CACNG2	No	1	APP
AHDC1	CTCF	No	1	FBL
KAT6A	DYRK1A	No	5	CREBBP, HIST1H3A, EP300, ELAVL1, HIST1H4A
KAT6A	KMT2C	No	4	WDR5, ELAVL1, HIST1H3A, HIST2H3C
KAT6A	GATAD2B	No	2	HIST1H3A, HIST1H4A
KAT6A	AUTS2	No	4	WDR5, EP300, ATN1, RERE
KAT6A	KIF1A	No	1	ESR1
KAT6A	CHAMP1	No	2	HIST3H3, RPL35
KAT6A	ARID1A	No	3	ESR1, ELAVL1, TP53
KAT6A	POGZ	No	2	HIST3H3, RPL35
KAT6A	SMARCE1	No	2	ESR1, ING5
DYRK1A	KMT2C	No	2	HIST1H3A, ELAVL1
DYRK1A	GATAD2B	No	3	NTRK1, HIST1H3A, HIST1H4A
DYRK1A	DYNC1H1	No	4	NTRK1, DYNLL1, SNCA, CCDC8
DYRK1A	AUTS2	No	2	EP300, DCAF7
DYRK1A	SETD5	No	1	NXF1
DYRK1A	PACS1	No	1	NTRK1
DYRK1A	KIF1A	No	1	NTRK1
DYRK1A	GRIN2B	No	1	PARK2
DYRK1A	ARID1A	No	4	NXF1, SMAD3, ELAVL1, MOV10
DYRK1A	PURA	No	2	NTRK1, RB1
DYRK1A	POGZ	No	4	NXF1, MOV10, APP, XPO1
DYRK1A	PPP2R5D	No	1	NTRK1
DYRK1A	CACNG2	No	1	APP
DYRK1A	CTCF	No	1	SMAD3
DYRK1A	SMARCE1	No	3	NXF1, MOV10, XPO1
GRIN1	GRIN2B	Yes	4	FYN, CAMK2G, SPTAN1, PRKCA
GRIN1	CACNG2	Yes	0
KMT2C	GATAD2B	No	1	HIST1H3A
KMT2C	DYNC1H1	No	1	TSC22D1
KMT2C	AUTS2	No	1	WDR5
KMT2C	ARID1B	No	1	SMARCB1
KMT2C	ARID1A	No	2	SMARCB1, ELAVL1
KMT2C	SMARCE1	No	3	JUN, RBBP5, SMARCB1
COL4A3BP	PPP2R5D	No	1	RANGAP1
SYNGAP1	GRIN2B	No	2	DLG3, DLG4
SYNGAP1	CACNG2	No	1	DLG4
GATAD2B	DYNC1H1	No	5	NTRK1, BRCA1, SUZ12, SMAD2, RNF2
GATAD2B	AUTS2	No	1	RNF2
GATAD2B	SETD5	No	1	CEP70
GATAD2B	PACS1	No	1	NTRK1
GATAD2B	KIF1A	No	4	RBPMS, NTRK1, TRAF1, TRIM27
GATAD2B	CHAMP1	No	1	SUMO2
GATAD2B	ARID1B	No	2	HIST2H2BE, SMAD2
GATAD2B	ARID1A	No	4	EED, TAT, SMAD2, SOX2
GATAD2B	PURA	No	1	NTRK1
GATAD2B	POGZ	No	7	RBPMS, FOXG1, EED, RNF2, FOXQ1, SUMO2, FOXJ2
GATAD2B	PPP2R5D	No	3	NTRK1, USHBP1, SOX2
GATAD2B	CTCF	No	4	EED, ZBTB33, HIST2H2AC, SUZ12
GATAD2B	SMARCE1	No	8	GOLGA2, HDAC1, HDAC2, HIST1H3E, CEP70, RNF2, USHBP1, CHD4
DYNC1H1	AUTS2	No	2	CSNK2B, RNF2
DYNC1H1	PACS1	No	1	NTRK1
DYNC1H1	KIF1A	No	3	NTRK1, EGFR, SIRT7
DYNC1H1	ARID1B	No	2	PRMT5, SMAD2
DYNC1H1	ARID1A	No	5	UNK, CUL3, SMAD2, SIRT7, CDC5L
DYNC1H1	PURA	No	3	NTRK1, BMI1, CUL3
DYNC1H1	POGZ	No	2	SIRT7, RNF2
DYNC1H1	PPP2R5D	No	4	NTRK1, CSNK2B, CRY2, RPA2
DYNC1H1	CTCF	No	4	BMI1, SUZ12, SIRT7, YBX1
DYNC1H1	SMARCE1	No	5	PRMT5, TNIK, DISC1, CUL3, RNF2
AUTS2	PACS1	No	1	CSNK2A1
AUTS2	POGZ	No	1	RNF2
AUTS2	PPP2R5D	No	1	CSNK2B
AUTS2	SMARCE1	No	1	RNF2
SETD5	KIF1A	No	1	MTUS2
SETD5	ARID1A	No	1	NXF1
SETD5	POGZ	No	1	NXF1
SETD5	SMARCE1	No	4	NXF1, MTUS2, KRT40, CEP70
PACS1	KIF1A	No	1	NTRK1
PACS1	PURA	No	1	NTRK1
PACS1	PPP2R5D	No	1	NTRK1
KIF1A	ARID1A	No	2	ESR1, SIRT7
KIF1A	PURA	No	2	SP1, NTRK1
KIF1A	POGZ	No	3	SP1, RBPMS, SIRT7
KIF1A	PPP2R5D	No	2	NTRK1, DLG4
KIF1A	CTCF	No	2	RXRA, SIRT7
KIF1A	SMARCE1	No	4	MTUS2, ESR1, AR, NOTCH2NL
CHAMP1	MBD5	No	1	HDGFRP2
CHAMP1	POGZ	Yes	11	CBX5, HIST3H3, MAD2L2, ZMYM4, MDC1, HDGFRP2, RPL35, CBX3, TMEM171, CBX1, SUMO2
CHAMP1	CTCF	No	1	ZMYM4
GRIN2B	ARID1B	No	1	KDM5B
GRIN2B	CACNG2	No	3	DLG4, GRIN1, DLG1
GRIN2B	SMARCE1	No	1	EXOC7
ARID1B	ARID1A	Yes	19	SMARCC1, SMARCE1, BCL7C, BCL7B, SMARCA4, DPF3, BCL7A, SMARCD1, SMARCB1, SMARCA2, DPF2, SMARCD2, SMARCC2, SMAD2, SMARCD3, ACTL6A, CUL2, YAP1, SS18
ARID1B	PURA	No	1	CAND1
ARID1B	CTCF	No	1	CAND1
ARID1B	SMARCE1	Yes	17	SMARCC1, BCL7C, BCL7B, SMARCA4, DPF3, SMARCD1, SMARCB1, PRMT5, SMARCA2, CAND1, SMARCD2, SMARCC2, DPF2, SMARCD3, ARID1A, ACTL6A, SS18
ARID1A	PURA	No	2	SNW1, CUL3
ARID1A	POGZ	No	4	EED, NXF1, MOV10, SIRT7
ARID1A	PPP2R5D	No	1	SOX2
ARID1A	CTCF	No	5	EED, TFAP4, SMAD3, CHD7, SIRT7
ARID1A	SMARCE1	Yes	31	RARB, KLF1, ESR1, PGR, EWSR1, NXF1, ARID1B, CARM1, DPF3, PBRM1, DPF2, SMARCD2, SMARCC2, SMARCD1, SMARCD3, TFAP4, PHF10, BCL7B, ITCH, ACTL6A, SMARCB1, BCL7C, CHD7, NCOA1, MOV10, SMARCC1, SMARCA2, CUL3, SMARCA4, GATA1, SS18
MBD5	POGZ	No	1	HDGFRP2
PURA	POGZ	No	1	SP1
PURA	PPP2R5D	No	1	NTRK1
PURA	CACNG2	No	1	CCNT1
PURA	CTCF	No	3	BMI1, PRR11, CAND1
PURA	SMARCE1	No	2	CUL3, CAND1
POGZ	CACNG2	No	1	APP
POGZ	CTCF	No	3	EED, ZMYM4, SIRT7
POGZ	SMARCE1	No	5	NXF1, MOV10, RNF2, ENO1, XPO1
PPP2R5D	CACNG2	No	2	GOPC, CSNK1E
PPP2R5D	SMARCE1	No	1	USHBP1
CTCF	SMARCE1	No	5	CAND1, TFAP4, SIN3A, CHD7, TOP2B

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
CTNNB1	SMARCA4	No	1	CREBBP
CTNNB1	MEF2C	No	1	EP300
DPP6	GRIN2B	No	1	TP53

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from STRING

Gene1	Gene2	Direct Interaction	Interaction mode	Number of shared interactors	Shared genes in interaction
EPB41L1	PPP2R1A	No	-	4	CACNG4, CACNG2, CACNG3, CACNG8
EPB41L1	CTNNB1	No	-	4	PIK3R1, MYO6, PIK3CA, DLG1
EPB41L1	MEF2C	No	-	4	CAMK2D, CAMK2A, CAMK2G, CAMK2B
EPB41L1	GRIN1	No	-	11	CACNG8, CAMK2A, GRIA1, CACNG3, CAMK2B, CACNG4, CACNG2, DLG1, DLG4, CAMK2D, CAMK2G
EPB41L1	KIRREL3	No	-	1	CASK
EPB41L1	GRIN2B	No	-	11	CACNG8, CAMK2A, GRIA1, CACNG3, CAMK2B, CACNG4, CACNG2, DLG1, DLG4, CAMK2D, CAMK2G
EPB41L1	PPP2R5D	No	-	4	CACNG4, CACNG2, CACNG3, CACNG8
EPB41L1	CACNG2	Yes	reaction, binding	13	MYO6, CAMK2A, GRIA1, CACNG3, CAMK2B, CACNG4, MDM2, CACNG8, DLG1, AKAP5, DLG4, CAMK2D, CAMK2G
CDH15	CTNNB1	Yes	activation	25	ABL1, CDH8, CDH10, CTNND1, CDC42, CDH11, CTNNA1, CDH18, CDH6, MAP2K6, SPAG9, CDH9, MAPK11, CDH17, MAPK12, CDH3, CDH1, JUP, CDH2, MAPK14, BNIP2, CDON, CTNNA2, CDH4, CDH5
CDH15	SMARCA4	No	-	2	CDH1, CTNNB1
CDH15	MEF2C	No	-	3	MAPK14, MAPK12, MAPK11
CDH15	PPP2R5D	No	-	1	CTNNB1
CDH15	CTCF	No	-	1	CDH1
ADNP	PPP2R1A	No	-	1	UBC
ADNP	EEF1A2	No	-	1	UBC
ADNP	CTNNB1	No	-	1	UBC
ADNP	SMARCB1	No	-	1	UBC
ADNP	SMARCA4	No	-	1	UBC
ADNP	EHMT1	No	-	1	UBC
ADNP	DYNC1H1	No	-	1	UBC
ADNP	KIF1A	No	-	1	UBC
ADNP	PURA	No	-	1	UBC
ADNP	PPP2R5D	No	-	1	UBC
ADNP	CTCF	No	-	1	UBC
ADNP	SMARCE1	No	-	1	UBC
PPP2R1A	EEF1A2	No	-	3	UBC, RPLP0, ETF1
PPP2R1A	CTNNB1	No	-	30	PTPN11, AKT1, CSNK1E, YWHAE, IL8, CSNK1D, EGFR, PRKACA, YWHAB, RPS27A, PPP2R5D, YWHAH, TUBA1A, FOXO3, YWHAZ, PPP2R5A, AKT2, SFN, PRKCI, SMAD2, UBC, RELA, NFKB1, AJUBA, PLK1, TGFBR2, YWHAG, PRKCA, EGF, YWHAQ
PPP2R1A	ZMYND11	No	-	1	TP53
PPP2R1A	SMARCB1	No	-	6	PLK1, PPP1CA, PPP1CB, TP53, RELA, UBC
PPP2R1A	SMARCA4	No	-	5	BANF1, UBC, SMAD2, TP53, RELA
PPP2R1A	EHMT1	No	-	5	UBC, UBA52, UBB, RPS27A, IL8
PPP2R1A	MEF2C	No	-	9	CDK1, MAPK3, PLK4, MAPK1, SMAD2, PPP3CB, PLK1, AKT1, PPP3CA
PPP2R1A	NR1I3	No	-	1	HSP90AA1
PPP2R1A	KAT6A	No	-	1	TP53
PPP2R1A	DYRK1A	No	-	9	YWHAH, YWHAE, TP53, SPRY2, YWHAG, YWHAB, SFN, YWHAQ, YWHAZ
PPP2R1A	GRIN1	No	-	10	CACNG3, CACNG4, CACNG8, CACNG7, CACNG5, PPP1CA, CACNG2, PPP1CB, PPP1CC, PRKACA
PPP2R1A	DYNC1H1	Yes	binding	65	CEP76, TUBGCP5, CDK1, CDK5RAP2, CEP57, CSNK1E, SSNA1, ACTR1A, YWHAE, CEP152, FGFR1OP, ALMS1, CSNK1D, TUBG2, PLK1, MAPRE1, TUBGCP6, PRKACA, CEP135, CEP192, SFI1, HAUS2, CEP250, DYNLL1, OFD1, CNTRL, TUBA1A, DYNC1I2, SDCCAG8, PCNT, YWHAG, TUBGCP2, CEP164, NEDD1, CEP290, CEP63, CCP110, DCTN3, CKAP5, AZI1, PRKAR2B, TUBB4B, HSP90AA1, ODF2, CENPJ, TUBA4A, PAFAH1B1, CEP78, CEP70, BORA, TUBGCP3, CLASP1, DCTN2, AJUBA, AURKA, NINL, NEK2, TUBGCP4, CEP72, PCM1, NDE1, UBC, TUBB4A, PLK4, TUBG1
PPP2R1A	PACS1	No	-	1	FGFR1OP
PPP2R1A	KIF1A	No	-	1	UBC
PPP2R1A	GRIN2B	No	-	11	CACNG3, PTPN11, CACNG4, CACNG8, CACNG7, CACNG5, PPP1CA, CACNG2, PPP1CB, PPP1CC, PRKACA
PPP2R1A	ARID1A	No	-	2	TP53, RELA
PPP2R1A	PURA	No	-	1	UBC
PPP2R1A	PPP2R5D	Yes	binding	51	CACNA2D4, TGFBR2, MAPK1, CACNA2D1, RYR2, PPP2CA, AKT3, PPP1CA, PPP2R2B, PPP2R2A, REC8, CACNG5, CACNG7, ARRB2, DRD2, CACNB2, CACNB3, PPP2CB, PPP1CC, PPP2R5A, AKT2, CACNG8, CACNG1, PRKAR2B, CACNA2D3, EIF4G1, TNNI3, RPS6KB1, CACNG3, AKT1, SGOL1, CACNB4, CDK1, CACNA1S, MAPK3, PPP1R1A, CACNG6, PPP2R3A, CACNG4, PPP4C, CACNA2D2, PPP2R3B, AURKA, CACNG2, PPP2R2C, PPP2R4, PPFIA1, UBC, EIF4A1, CACNB1, CACNA1D
PPP2R1A	CACNG2	Yes	inhibition, binding	32	CACNA2D4, PPP2R5D, CACNA2D1, PPP2CA, PPP1CA, PPP2R2A, PRKACA, CACNB1, CACNG7, CACNB2, PPP2CB, PPP1CC, PPP2R5C, PPP2R5A, CACNA1S, CACNG8, CACNG1, PPP1CB, PPP2R2B, CACNG5, CACNG3, CACNB3, PPP2R3C, CACNG6, PPP2R3A, CACNG4, PPP2R3B, PPP2R2C, PPP2R5B, PPP2R5E, CACNB4, CACNA1D
PPP2R1A	CTCF	No	-	3	UBC, RPS6KB1, TP53
PPP2R1A	SMARCE1	No	-	3	BANF1, UBC, RELA
EEF1A2	CTNNB1	No	-	3	UBC, FOS, ACTA1
EEF1A2	SMARCB1	No	-	3	UBC, JUNB, ACTA1
EEF1A2	SMARCA4	No	-	4	UBC, FOS, JUNB, ACTC1
EEF1A2	EHMT1	No	-	1	UBC
EEF1A2	MEF2C	No	-	1	ACTA1
EEF1A2	DYNC1H1	No	-	1	UBC
EEF1A2	KIF1A	No	-	1	UBC
EEF1A2	ARID1A	No	-	0
EEF1A2	PURA	No	-	1	UBC
EEF1A2	PPP2R5D	No	-	1	UBC
EEF1A2	CTCF	No	-	1	UBC
EEF1A2	SMARCE1	No	-	1	UBC
CTNNB1	ZMYND11	No	-	1	EP400
CTNNB1	SMARCB1	No	-	17	KAT2B, MYC, RELA, ACTA1, HDAC1, HDAC2, MLLT10, PLK1, SMARCA5, JUN, SMARCA4, CREBBP, UBC, BRCA1, FGFR1, CCND1, IRF3
CTNNB1	SMARCA4	Yes	activation, binding	39	KAT2B, AR, HIST3H3, MITF, EZH2, HDAC9, FOS, KAT5, RUVBL1, CCNE1, TRRAP, CCND1, HDAC7, SMAD3, BRCA1, TCF7L1, LEF1, HDAC1, SMAD2, UBC, JUN, TOP2A, CDH1, RUVBL2, MYOD1, EP300, CREBBP, STAT3, TBX5, HDAC2, MMP9, MMP2, IRF3, TERT, NANOG, MYC, RELA, TCF7L2, MYOG
CTNNB1	EHMT1	No	-	9	RPS27A, HIST3H3, HDAC1, HDAC2, IL8, SMARCA4, UBC, HDAC9, CTBP1
CTNNB1	MEF2C	No	-	23	KAT2B, SMAD4, MYF5, HDAC9, MAPK11, ACTA1, TCF3, HDAC7, SMAD3, NCOA2, MAPK12, SMAD2, JUN, AKT1, MYOD1, VEGFA, EP300, MAPK14, NOTCH1, CREBBP, CAMK4, PLK1, MYOG
CTNNB1	KANSL1	No	-	4	CHD8, RBBP5, RUVBL1, RUVBL2
CTNNB1	NR1I3	No	-	2	MED1, NR0B1
CTNNB1	KAT6A	No	-	6	KAT2B, HIST3H3, CREBBP, TRRAP, SMARCA4, EP300
CTNNB1	DYRK1A	No	-	13	NOTCH1, FOXO1, CCND1, YWHAE, DNM2, YWHAG, YWHAZ, SFN, YWHAB, PRKACB, YWHAQ, YWHAH, SIRT1
CTNNB1	GRIN1	No	-	7	GRIA2, PRKX, PRKACG, DLG1, SRC, PRKACA, PRKACB
CTNNB1	DYNC1H1	No	-	10	CSNK1E, HTT, AJUBA, YWHAE, TUBA1A, PLK1, CSNK1D, YWHAG, UBC, PRKACA
CTNNB1	AUTS2	No	-	1	CSNK2A1
CTNNB1	PACS1	No	-	1	CSNK2A1
CTNNB1	KIF1A	No	-	3	UBC, GRIA2, CTTN
CTNNB1	GRIN2B	No	-	13	GRIA2, PRKX, CDK2, ARHGAP32, PTPN11, BDNF, PRKACG, PRKACB, PRKACA, SRC, FYN, VEGFA, DLG1
CTNNB1	ARID1B	No	-	1	SMARCA4
CTNNB1	ARID1A	No	-	8	KAT2B, SMARCA4, HIC1, XPO1, JUN, RELA, CREBBP, IRF3
CTNNB1	PURA	No	-	1	UBC
CTNNB1	PPP2R5D	Yes	activation	13	DVL1, PPP2R5A, AKT2, TGFBR2, PROC, TERT, AXIN1, TGFBR1, MTOR, PRKACG, AKT1, UBC, PRKACB
CTNNB1	CACNG2	No	-	11	PPP2R5A, GRIA2, PPP2R5D, MYO6, MAGI2, PRKX, CACNA1G, PRKACG, PRKACB, PRKACA, DLG1
CTNNB1	CTCF	No	-	9	PTGS2, BIRC5, SMAD4, SMAD3, CDH1, UBC, HDAC9, MYC, CDKN1B
CTNNB1	SMARCE1	No	-	11	KAT2B, KLK3, SMARCA4, CREBBP, AR, UBC, JUN, IRF3, RELA, SRC, MYOG
ZMYND11	SMARCB1	No	-	1	TP53
ZMYND11	SMARCA4	No	-	1	TP53
ZMYND11	KAT6A	No	-	1	TP53
ZMYND11	DYRK1A	No	-	1	TP53
ZMYND11	ARID1A	No	-	1	TP53
ZMYND11	CTCF	No	-	1	TP53
SMARCB1	SMARCA4	Yes	activation, binding	63	KAT2B, KAT2A, IRF5, GTF2B, SMARCC2, KLF1, IRF2, TP53, GTF2A1, GTF3A, ARID1A, XPC, PHF7, YEATS4, SMARCD2, RAD52, ESR2, DPF3, CCND1, PBRM1, POLR2A, IRF7, SMARCE1, ZNF14, DPF1, BRCA1, ACTL6A, PHF10, SMARCC1, CDKN1A, IFNB1, SMARCD3, GTF2E1, ACTL6B, HDAC1, SIN3A, SMARCA2, ATF2, UBC, JUN, ARID1B, RELA, ASH1L, ARID2, MYC, SMARCD1, SMARCA1, CREBBP, HMGB1, IRF4, NR3C1, RBBP4, IRF6, HDAC2, MYSM1, CEBPB, RB1, GTF2F1, PHF11, JUNB, MLLT1, IRF1, IRF3
SMARCB1	EHMT1	No	-	5	UBC, HDAC1, HDAC2, SMARCA2, SMARCA4
SMARCB1	MEF2C	No	-	12	KAT2B, GTF3A, GTF2E1, NR3C1, CREBBP, ACTA1, RB1, PLK1, JUN, GTF2A1, POLR2A, GTF2F1
SMARCB1	KANSL1	No	-	0
SMARCB1	KAT6A	No	-	8	KAT2B, KAT2A, CREBBP, SMARCA2, TP53, SMARCA4, YEATS4, MLLT1
SMARCB1	DYRK1A	No	-	3	CCND1, RBBP4, TP53
SMARCB1	GRIN1	No	-	2	PPP1CA, PPP1CB
SMARCB1	DYNC1H1	No	-	2	UBC, PLK1
SMARCB1	KIF1A	No	-	1	UBC
SMARCB1	GRIN2B	No	-	2	PPP1CA, PPP1CB
SMARCB1	ARID1B	Yes	binding	16	SMARCC1, SMARCD2, SMARCA2, SMARCD3, DPF3, HELLS, ACTL6B, RB1, SMARCE1, SMARCC2, SMARCD1, DPF1, ACTL6A, ARID1A, SMARCA4, PHF10
SMARCB1	ARID1A	Yes	binding	39	KAT2B, IRF2, GTF2B, HELLS, ACTL6A, IRF5, TP53, GTF2A1, SMARCD2, DPF3, PBRM1, POLR2A, IRF7, SMARCE1, SMARCC2, DPF1, PHF10, GTF3A, SMARCD3, IFNB1, ARID1B, GTF2E1, ACTL6B, SMARCA2, ATF2, JUN, RELA, SMARCD1, SMARCC1, CREBBP, HMGB1, IRF4, NR3C1, IRF1, RB1, GTF2F1, SMARCA4, IRF6, IRF3
SMARCB1	PURA	No	-	1	UBC
SMARCB1	PPP2R5D	No	-	2	UBC, PPP1CA
SMARCB1	CACNG2	No	-	2	PPP1CA, PPP1CB
SMARCB1	CTCF	No	-	5	UBC, POLR2A, SIN3A, MYC, TP53
SMARCB1	SMARCE1	Yes	binding	42	KAT2B, IRF2, IRF4, GTF2B, HELLS, ACTL6A, IRF5, GTF2A1, ARID1A, ESR2, DPF3, PBRM1, SMARCC2, IRF7, SMARCD2, ZNF14, DPF1, PHF10, GTF3A, SMARCD3, IFNB1, ARID1B, GTF2E1, ACTL6B, SMARCA2, ATF2, JUN, RELA, ARID2, SMARCD1, SMARCC1, CREBBP, HMGB1, POLR2A, NR3C1, IRF1, RB1, GTF2F1, SMARCA4, UBC, IRF6, IRF3
SMARCA4	EHMT1	Yes	activation	13	SMARCA2, HIST3H3, BRD1, HDAC1, HDAC2, H3F3A, HIST1H3A, HDAC3, DDB1, KDM6A, UBC, HDAC9, BRPF3
SMARCA4	MEF2C	No	-	24	KAT2B, GTF3A, TBP, TBPL2, HDAC4, GTF2A1, HDAC9, CARM1, HDAC3, HDAC7, SMAD3, HDAC5, GTF2F1, GTF2E1, SMAD2, JUN, MYOD1, EP300, E2F1, POLR2A, NR3C1, CREBBP, RB1, MYOG
SMARCA4	KANSL1	No	-	6	E2F6, RUVBL1, KAT8, TAF1, RUVBL2, MCRS1
SMARCA4	SOX11	No	-	2	PAX2, PAX5
SMARCA4	MYT1L	No	-	1	SIN3B
SMARCA4	KAT6A	Yes	activation, binding	18	KAT2B, KAT6B, KAT2A, HIST3H3, BRD1, EP300, TP53, SMARCA2, YEATS4, SUPT16H, TRRAP, MLLT3, TAF1, CREBBP, BRPF3, MLLT1, HIST1H3A, H2AFZ
SMARCA4	DYRK1A	No	-	3	CCND1, RBBP4, TP53
SMARCA4	GRIN1	No	-	1	SPTAN1
SMARCA4	GATAD2B	No	-	1	MBD3
SMARCA4	DYNC1H1	No	-	1	UBC
SMARCA4	KIF1A	No	-	1	UBC
SMARCA4	GRIN2B	No	-	1	CREB1
SMARCA4	ARID1B	Yes	activation, binding	15	SMARCC1, SMARCD2, SMARCA2, SMARCD3, DPF3, ACTL6B, RB1, SMARCE1, SMARCC2, SMARCD1, DPF1, ACTL6A, ARID1A, SMARCB1, PHF10
SMARCA4	ARID1A	Yes	activation, binding	42	KAT2B, IRF2, GTF2B, ACTL6A, IRF5, TP53, GTF2A1, ARID1B, TOP2B, SMARCD2, DPF3, PBRM1, POLR2A, IRF7, SMARCE1, SMARCC2, CHAF1A, ACTL6B, PHF10, GTF3A, SMARCD3, IFNB1, DPF1, GTF2E1, VDR, SMARCB1, SMARCA2, SUPT16H, JUN, ATF2, RELA, SMARCD1, SMARCC1, CREBBP, HMGB1, IRF4, NR3C1, IRF1, RB1, GTF2F1, IRF6, IRF3
SMARCA4	PURA	No	-	2	UBC, RPA1
SMARCA4	PPP2R5D	No	-	3	UBC, TERT, CTNNB1
SMARCA4	CTCF	No	-	12	MYC, SIN3A, TAF1, CDH1, POLR2A, SMAD3, TP53, UBC, HDAC9, SUMO2, PAX6, H2AFZ
SMARCA4	SMARCE1	Yes	activation, binding	53	KAT2B, AR, IRF4, GTF2B, ACTL6A, IRF2, IRF5, IRF7, GTF2A1, ARID1A, ARID1B, TOP2B, CARM1, ESR2, DPF3, PBRM1, SMARCC2, DPF2, SMARCD2, ZNF14, GTF2F1, SMARCD3, SMARCB1, PHF10, BANF1, GTF3A, IFNB1, CHAF1A, GTF2E1, VDR, CHD4, ACTL6B, SMARCA2, SUPT16H, JUN, ATF2, RELA, ZMIZ2, ARID2, SMARCD1, SMARCC1, CREBBP, HMGB1, POLR2A, NR3C1, IRF1, RB1, IRF3, ESR1, UBC, IRF6, MYOG, DPF1
EHMT1	MEF2C	No	-	2	HDAC9, HDAC3
EHMT1	KANSL1	No	-	1	WDR5
EHMT1	KAT6A	No	-	6	SMARCA2, HIST3H3, BRD1, SMARCA4, BRPF3, HIST1H3A
EHMT1	DYNC1H1	No	-	1	UBC
EHMT1	KIF1A	No	-	1	UBC
EHMT1	GRIN2B	No	-	1	SETDB1
EHMT1	ARID1B	No	-	2	SMARCA2, SMARCA4
EHMT1	ARID1A	No	-	2	SMARCA2, SMARCA4
EHMT1	PURA	No	-	1	UBC
EHMT1	PPP2R5D	No	-	1	UBC
EHMT1	CTCF	No	-	2	UBC, HDAC9
EHMT1	SMARCE1	No	-	3	UBC, SMARCA2, SMARCA4
MEF2C	KAT6A	No	-	3	KAT2B, CREBBP, EP300
MEF2C	DYRK1A	No	-	1	NOTCH1
MEF2C	GRIN1	No	-	4	CAMK2D, CAMK2A, CAMK2G, CAMK2B
MEF2C	DYNC1H1	No	-	3	CDK1, PLK4, PLK1
MEF2C	GRIN2B	No	-	6	CAMK2A, CAMK2B, CAMK2D, VEGFA, CDK5, CAMK2G
MEF2C	ARID1B	No	-	1	RB1
MEF2C	ARID1A	No	-	10	KAT2B, GTF3A, GTF2E1, NR3C1, CREBBP, JUN, RB1, GTF2A1, POLR2A, GTF2F1
MEF2C	PPP2R5D	No	-	6	CDK1, MAPK1, MAPK3, AKT1, CDK5, MAPK7
MEF2C	CACNG2	No	-	4	CAMK2D, CAMK2A, CAMK2G, CAMK2B
MEF2C	CTCF	No	-	4	HDAC9, SMAD3, POLR2A, SMAD4
MEF2C	SMARCE1	No	-	12	KAT2B, GTF3A, CARM1, GTF2E1, NR3C1, CREBBP, JUN, RB1, MYOG, GTF2A1, POLR2A, GTF2F1
KANSL1	KAT6A	No	-	1	TAF1
KANSL1	CTCF	No	-	1	TAF1
NR1I3	DYNC1H1	No	-	1	HSP90AA1
KAT6A	DYRK1A	No	-	1	TP53
KAT6A	ARID1B	No	-	2	SMARCA2, SMARCA4
KAT6A	ARID1A	No	-	6	KAT2B, SMARCA2, CREBBP, SUPT16H, TP53, SMARCA4
KAT6A	CTCF	No	-	3	TAF1, H2AFZ, TP53
KAT6A	SMARCE1	No	-	5	KAT2B, CREBBP, SMARCA2, SMARCA4, SUPT16H
DYRK1A	GRIN1	No	-	1	PRKACB
DYRK1A	DYNC1H1	No	-	2	YWHAE, YWHAG
DYRK1A	GRIN2B	No	-	1	PRKACB
DYRK1A	ARID1A	No	-	1	TP53
DYRK1A	PPP2R5D	No	-	4	PRKAR1A, SNCA, MAPT, PRKACB
DYRK1A	CACNG2	No	-	1	PRKACB
DYRK1A	CTCF	No	-	1	TP53
GRIN1	DYNC1H1	No	-	1	PRKACA
GRIN1	KIF1A	No	-	1	GRIA2
GRIN1	GRIN2B	Yes	binding	42	PRKACG, CNIH3, RASGRF1, CACNG2, PPP1CA, GRM5, CAMK2B, PRKACA, DLG1, CACNG4, NOS1, PRKX, CACNG7, DLG3, DLG4, GRIN2D, CAMK2G, GRIA2, CACNG8, GRIA3, HRAS, CNIH2, PPP1CB, GRIN3B, CACNG3, GRIN2A, SRC, CAMK2D, PPP1CC, RASGRF2, ACTN2, SHISA9, CAMK2A, GRIN3A, PTK2B, GRIA1, CACNG5, DLG2, GRM1, PRKACB, GRIA4, GRIN2C
GRIN1	PPP2R5D	No	-	10	CACNG4, CACNG8, CACNG7, CACNG2, PPP1CA, PRKACG, CACNG3, CACNG5, PPP1CC, PRKACB
GRIN1	CACNG2	Yes	binding	32	PRKACG, CNIH3, CACNG4, PPP1CA, CAMK2B, PRKACA, DLG1, PRKX, CACNG7, DLG3, GRIN2B, PPP1CC, CAMK2G, GRIA2, CACNG8, GRIA3, CNIH2, PPP1CB, GRIK1, GRIN3B, CACNG3, GRIN2A, CAMK2D, DLG4, SHISA9, CAMK2A, GRIN3A, GRIA4, GRIA1, CACNG5, GRIK2, PRKACB
GRIN1	SMARCE1	No	-	1	SRC
DYNC1H1	PACS1	No	-	1	FGFR1OP
DYNC1H1	KIF1A	No	-	1	UBC
DYNC1H1	GRIN2B	No	-	1	PRKACA
DYNC1H1	PURA	No	-	1	UBC
DYNC1H1	PPP2R5D	No	-	6	CDK1, MAP1B, PRKAR2B, AURKA, UBC, PPP2R1A
DYNC1H1	CACNG2	No	-	2	PPP2R1A, PRKACA
DYNC1H1	CTCF	No	-	1	UBC
DYNC1H1	SMARCE1	No	-	1	UBC
AUTS2	PACS1	No	-	1	CSNK2A1
KIF1A	GRIN2B	No	-	1	GRIA2
KIF1A	PURA	No	-	1	UBC
KIF1A	PPP2R5D	No	-	1	UBC
KIF1A	CACNG2	No	-	1	GRIA2
KIF1A	CTCF	No	-	1	UBC
KIF1A	SMARCE1	No	-	1	UBC
GRIN2B	ARID1A	No	-	1	MIB2
GRIN2B	PPP2R5D	No	-	11	CACNG4, CACNG8, CACNG7, CACNG2, PPP1CA, PRKACG, CACNG3, CACNG5, PPP1CC, CDK5, PRKACB
GRIN2B	CACNG2	Yes	binding	30	PRKACG, CNIH3, CACNG4, CAMK2B, PRKACA, DLG1, PRKX, CACNG7, DLG3, PPP1CC, CAMK2G, GRIA2, CACNG8, GRIA3, CNIH2, PPP1CB, CACNG5, CACNG3, GRIN2A, CAMK2D, DLG4, SHISA9, CAMK2A, GRIN3A, GRIA4, GRIA1, GRIN3B, PPP1CA, PRKACB, GRIN1
GRIN2B	SMARCE1	No	-	1	SRC
ARID1B	ARID1A	Yes	binding	16	SMARCC1, SMARCD2, SMARCA2, SMARCD3, DPF3, HELLS, ACTL6B, RB1, SMARCE1, SMARCC2, SMARCD1, DPF1, ACTL6A, SMARCA4, SMARCB1, PHF10
ARID1B	SMARCE1	Yes	binding	16	SMARCC1, SMARCA2, SMARCD3, DPF3, HELLS, ACTL6B, RB1, SMARCD2, SMARCC2, SMARCD1, DPF1, ACTL6A, SMARCA4, ARID1A, SMARCB1, PHF10
ARID1A	CTCF	No	-	2	POLR2A, TP53
ARID1A	SMARCE1	Yes	binding	42	KAT2B, IRF2, GTF2B, HELLS, ACTL6A, IRF5, GTF2A1, ARID1B, TOP2B, DPF3, PBRM1, POLR2A, IRF7, SMARCD2, SMARCC2, CHAF1A, ACTL6B, PHF10, GTF3A, SMARCD3, IFNB1, DPF1, GTF2E1, VDR, SMARCB1, SMARCA2, SUPT16H, JUN, ATF2, RELA, SMARCD1, SMARCC1, CREBBP, HMGB1, IRF4, NR3C1, IRF1, RB1, GTF2F1, SMARCA4, IRF6, IRF3
PURA	PPP2R5D	No	-	1	UBC
PURA	CTCF	No	-	1	UBC
PURA	SMARCE1	No	-	1	UBC
PPP2R5D	CACNG2	Yes	inhibition, binding	29	CACNA2D4, CACNA2D1, PPP2CA, PPP2R2C, PPP1CA, PPP2R2A, CACNB1, CACNB2, PPP2CB, PPP1CC, PRKACB, PPP2R5A, CACNG8, CACNG1, CACNG3, PPP2R2B, PRKACG, CACNG7, PPP2R1A, CACNB3, CACNA1S, CACNG6, PPP2R3A, CACNG4, PPP2R3B, CACNG5, PPP2R1B, CACNB4, CACNA1D
PPP2R5D	CTCF	No	-	2	UBC, RPS6KB1
PPP2R5D	SMARCE1	No	-	1	UBC
CTCF	SMARCE1	No	-	2	UBC, POLR2A

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM

Gene1	Gene2	Direct Interaction	Complexes	Number of shared interactors	Shared genes in interaction
CTNNB1	SMARCB1	No	-	2	CREBBP, EP300
CTNNB1	SMARCA4	No	-	2	CREBBP, EP300
CTNNB1	DYNC1H1	No	-	1	TCF4
CTNNB1	ARID1B	No	-	1	CREBBP
CTNNB1	ARID1A	No	-	2	CREBBP, EP300
SMARCB1	SMARCA4	Yes	SWI-SNF chromatin remodeling-related-BRCA1 complex;EBAFa complex;PBAF complex (Polybromo- and BAF containing complex);NUMAC complex (nucleosomal methylation activator complex);SIN3-ING1b complex II;WINAC complex;ETS2-SMARCA4-INI1 complex;EBAFb complex;RNA polymerase II complex, chromatin structure modifying;Brg1-associated complex I;BRG1-associated complex;Brg1-associated complex II;BRG1-SIN3A complex;NCOR1 complex;BAF complex;p300-CBP-p270-SWI/SNF complex;BRG1-SIN3A-HDAC containing SWI/SNF remodeling complex I;LARC complex (LCR-associated remodeling complex)	64	KAT2B, HNRNPC, MBD2, GTF2B, RBBP4, TBP, HDAC2, ACTL6A, TRIM28, ETS2, ING1, PRMT5, RBBP7, ARID1A, NCOR1, SMARCD2, CARM1, CCNC, ARID2, GTF2H1, PBRM1, SMARCC2, DPF2, SMARCE1, CDK8, HDAC3, TOP2B, CHAF1A, BAZ1B, BRCA1, HDAC1, GTF2F1, MBD3, ACTL6B, SMARCD3, ARID1B, GTF2E1, VDR, SIN3A, CHD4, ACTG1, ARID4B, SUPT16H, DRAP1, SAP30, MTA2, ERCC3, SRCAP, SF3B3, SMARCC1, SMARCA2, EP300, POLR2A, SF3A1, SMARCD1, CREBBP, SCYL1, ACTB, GATAD2B, MED21, PCSK4, SAP18, MLLT1, GTF2H3
SMARCB1	EHMT1	No	-	4	KDM1A, HDAC1, HDAC2, RCOR1
SMARCB1	KANSL1	No	-	6	KMT2A, WDR5, TAF9, RBBP5, TAF1, TAF6
SMARCB1	KMT2C	No	-	3	DPY30, WDR5, RBBP5
SMARCB1	GATAD2B	Yes	LARC complex (LCR-associated remodeling complex)	20	SMARCC1, SMARCD2, MBD3, MTA2, ACTL6A, ACTB, CHD4, HDAC2, MBD2, CHD3, SMARCE1, HNRNPC, SMARCC2, RBBP7, DPF2, SMARCA4, ARID1A, RBBP4, HDAC1, RCOR1
SMARCB1	ARID1B	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	15	SMARCC1, SMARCD2, SMARCA2, ACTL6A, ACTL6B, ACTG1, ACTB, SMARCE1, SMARCC2, SMARCA4, CREBBP, BRCA1, MLLT1, ARID1A, SMARCD1
SMARCB1	ARID1A	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	41	HNRNPC, MBD2, HDAC2, ACTL6A, SAP30, PRMT5, RBBP7, TOP2B, SMARCD2, CARM1, MBD3, DPF2, SMARCE1, SMARCC2, CHAF1A, BAZ1B, BRCA1, HDAC1, ACTL6B, SMARCD3, SMARCA4, VDR, SIN3A, CHD4, ACTG1, SMARCA2, SUPT16H, ACTB, MTA2, EP300, SMARCD1, SMARCC1, ARID4B, RBBP4, CREBBP, SCYL1, GATAD2B, ARID1B, SAP18, MLLT1, ING1
SMARCB1	SMARCE1	Yes	SWI-SNF chromatin remodeling-related-BRCA1 complex;EBAFa complex;PBAF complex (Polybromo- and BAF containing complex);NUMAC complex (nucleosomal methylation activator complex);WINAC complex;BRM-associated complex;EBAFb complex;RNA polymerase II complex, chromatin structure modifying;Brm-associated complex;Brg1-associated complex I;BRG1-associated complex;BRG1-SIN3A complex;BRM-SIN3A complex;BAF complex;BRM-SIN3A-HDAC complex;BRG1-SIN3A-HDAC containing SWI/SNF remodeling complex I;LARC complex (LCR-associated remodeling complex)	39	MBD2, HDAC2, ACTL6A, PRMT5, GATAD2B, ARID1A, TOP2B, CHD4, CARM1, PBRM1, CCNC, DPF2, SMARCD2, SMARCC2, CHAF1A, BAZ1B, BRCA1, ACTL6B, SMARCD3, VDR, SIN3A, HDAC1, ACTG1, HNRNPC, SUPT16H, ACTB, MTA2, ARID2, SMARCD1, SMARCC1, SMARCA2, RBBP4, SCYL1, CDK8, MED21, MBD3, SMARCA4, MLLT1, ARID1B
SMARCA4	EHMT1	No	-	2	HDAC1, HDAC2
SMARCA4	GATAD2B	Yes	LARC complex (LCR-associated remodeling complex)	18	SMARCC1, SMARCD2, MBD3, ACTL6A, ACTB, HDAC2, CHD4, SMARCB1, MBD2, DPF2, SMARCE1, HNRNPC, SMARCC2, RBBP7, MTA2, ARID1A, RBBP4, HDAC1
SMARCA4	ARID1B	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	20	SMARCC1, ACTL6B, TRIM33, NCOA3, SMARCB1, SMARCA2, ACTG1, ACTB, SMAD4, SMARCE1, SMARCC2, SMAD3, SMAD2, ACTL6A, CREBBP, ARID1A, MLLT1, BRCA1, SMARCD1, SMARCD2
SMARCA4	ARID1A	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	41	MBD2, HDAC2, ACTL6A, SMARCB1, SAP30, PRMT5, RBBP7, TOP2B, SMARCD2, CARM1, MBD3, SMARCA2, DPF2, SMARCE1, SMARCC2, CHAF1A, BAZ1B, BRCA1, HDAC1, ACTL6B, SMARCD3, VDR, SIN3A, CHD4, ACTG1, ARID4B, SUPT16H, ACTB, MTA2, EP300, SMARCD1, SMARCC1, HNRNPC, RBBP4, CREBBP, SCYL1, GATAD2B, ARID1B, SAP18, MLLT1, ING1
SMARCA4	CTCF	No	-	2	SMAD3, SMAD4
SMARCA4	SMARCE1	Yes	BAF complex	39	MBD2, HDAC2, ACTL6A, SMARCB1, PRMT5, GATAD2B, ARID1A, TOP2B, CHD4, CARM1, PBRM1, CCNC, DPF2, SMARCD2, SMARCC2, CHAF1A, BAZ1B, BRCA1, HDAC1, SMARCD3, VDR, SIN3A, ACTL6B, ACTG1, HNRNPC, SUPT16H, ACTB, MTA2, ARID2, SMARCD1, SMARCC1, SMARCA2, RBBP4, SCYL1, CDK8, MED21, MBD3, MLLT1, ARID1B
EHMT1	KANSL1	No	-	2	E2F6, RNF2
EHMT1	GATAD2B	No	-	3	HDAC1, HDAC2, RCOR1
EHMT1	ARID1A	No	-	2	HDAC1, HDAC2
EHMT1	SMARCE1	No	-	2	HDAC1, HDAC2
KANSL1	KMT2C	No	-	3	WDR5, ASH2L, RBBP5
GATAD2B	ARID1B	No	-	9	SMARCC1, SMARCD2, SMARCB1, ACTB, SMARCE1, SMARCC2, SMARCA4, ARID1A, ACTL6A
GATAD2B	ARID1A	Yes	LARC complex (LCR-associated remodeling complex)	18	SMARCC1, SMARCD2, MBD3, MTA2, ACTL6A, ACTB, HDAC2, CHD4, SMARCB1, MBD2, DPF2, SMARCE1, HNRNPC, SMARCC2, RBBP7, SMARCA4, RBBP4, HDAC1
GATAD2B	SMARCE1	Yes	LARC complex (LCR-associated remodeling complex)	17	SMARCC1, HNRNPC, MBD3, MTA2, ACTL6A, ACTB, HDAC2, CHD4, SMARCB1, MBD2, DPF2, SMARCD2, SMARCC2, SMARCA4, ARID1A, RBBP4, HDAC1
DYNC1H1	CTCF	No	-	1	TOP2A
ARID1B	ARID1A	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	15	SMARCC1, SMARCD2, SMARCA2, ACTL6A, SMARCB1, ACTG1, ACTB, SMARCE1, SMARCC2, SMARCA4, CREBBP, BRCA1, MLLT1, ACTL6B, SMARCD1
ARID1B	CTCF	No	-	2	SMAD3, SMAD4
ARID1B	SMARCE1	Yes	EBAFb complex	14	SMARCC1, ACTL6B, SMARCA2, ACTL6A, SMARCB1, ACTG1, ACTB, SMARCD2, SMARCC2, SMARCA4, BRCA1, MLLT1, ARID1A, SMARCD1
ARID1A	SMARCE1	Yes	BAF complex;SWI-SNF chromatin remodeling-related-BRCA1 complex	34	MBD2, HDAC2, ACTL6A, SMARCB1, TOP2B, CHD4, CARM1, SIN3A, DPF2, SMARCD2, SMARCC2, CHAF1A, BAZ1B, BRCA1, HDAC1, SMARCD3, VDR, PRMT5, ACTL6B, ACTG1, HNRNPC, SUPT16H, ACTB, MTA2, SMARCD1, SMARCC1, SMARCA2, RBBP4, SCYL1, GATAD2B, MBD3, SMARCA4, MLLT1, ARID1B

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CENSUS

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
ADNP	SMARCB1	No	1	SAP18
PPP2R1A	PPP2R5D	Yes	0
SMARCB1	SMARCA4	Yes	11	SMARCC1, SMARCE1, SMARCA2, SMARCD1, TOP2B, SMARCD2, SMARCC2, PHF10, SMARCD3, ARID1A, ARID1B
SMARCB1	ARID1B	Yes	7	SMARCC1, SMARCA2, SMARCE1, SMARCC2, SMARCA4, ARID1A, SMARCD1
SMARCB1	ARID1A	Yes	10	SMARCC1, SMARCE1, SMARCA2, SMARCD1, SMARCA4, SMARCD2, SMARCC2, PHF10, SMARCD3, ARID1B
SMARCB1	SMARCE1	Yes	12	SMARCC1, SMARCA2, SMARCD1, SMARCD3, PHF10, SMARCD2, SMARCC2, ARID1B, DPF1, ARID1A, SMARCA4, TOP2B
SMARCA4	ARID1B	Yes	8	SMARCC1, SMARCA2, SMARCB1, SMARCE1, SMARCC2, ARID1A, ACTL6A, SMARCD1
SMARCA4	ARID1A	Yes	11	SMARCC1, SMARCD2, SMARCA2, SMARCD1, SMARCB1, SMARCE1, SMARCC2, PHF10, SMARCD3, ACTL6A, ARID1B
SMARCA4	SMARCE1	Yes	12	SMARCC1, SMARCA2, SMARCB1, TOP2B, PHF10, SMARCD2, SMARCC2, SMARCD1, SMARCD3, ARID1A, ACTL6A, ARID1B
KANSL1	CTCF	Yes	0
ARID1B	ARID1A	Yes	8	SMARCC1, SMARCA2, SMARCB1, SMARCE1, SMARCC2, SMARCA4, ACTL6A, SMARCD1
ARID1B	SMARCE1	Yes	8	SMARCC1, SMARCA2, ACTL6A, SMARCC2, SMARCA4, ARID1A, SMARCB1, SMARCD1
ARID1A	SMARCE1	Yes	11	SMARCC1, SMARCA2, SMARCD1, SMARCA4, SMARCB1, SMARCD2, SMARCC2, PHF10, SMARCD3, ACTL6A, ARID1B

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from PDB

Interactions from manually curated literature

KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG term	KEGG term ID	IC	Number of genes with the same term	Genes
Tight junction	hsa04530	5.53	3	PPP2R1A, EPB41L1, CTNNB1
Dopaminergic synapse	hsa04728	5.69	3	PPP2R1A, GRIN2B, PPP2R5D
Rap1 signaling pathway	hsa04015	4.97	3	GRIN2B, GRIN1, CTNNB1
Ras signaling pathway	hsa04014	4.9	3	GRIN2B, GRIN1, SYNGAP1
Adrenergic signaling in cardiomyocytes	hsa04261	5.44	3	PPP2R1A, CACNG2, PPP2R5D
Signaling pathways regulating pluripotency of stem cells	hsa04550	5.6	2	KAT6A, CTNNB1
cAMP signaling pathway	hsa04024	5.05	2	GRIN2B, GRIN1
Long-term potentiation	hsa04720	6.64	2	GRIN2B, GRIN1
Glutamatergic synapse	hsa04724	5.84	2	GRIN2B, GRIN1
Arrhythmogenic right ventricular cardiomyopathy (ARVC)	hsa05412	6.32	2	CACNG2, CTNNB1
Oxytocin signaling pathway	hsa04921	5.4	2	MEF2C, CACNG2
Oocyte meiosis	hsa04114	5.91	2	PPP2R1A, PPP2R5D
mRNA surveillance pathway	hsa03015	6.28	2	PPP2R1A, PPP2R5D
Hippo signaling pathway	hsa04390	5.37	2	PPP2R1A, CTNNB1
MAPK signaling pathway	hsa04010	4.63	2	MEF2C, CACNG2
Circadian entrainment	hsa04713	6.11	2	GRIN2B, GRIN1
AMPK signaling pathway	hsa04152	5.8	2	PPP2R1A, PPP2R5D
PI3K-Akt signaling pathway	hsa04151	4.21	2	PPP2R1A, PPP2R5D
Lysine degradation	hsa00310	7.01	2	EHMT1, KMT2C
Neuroactive ligand-receptor interaction	hsa04080	4.58	2	GRIN2B, GRIN1
Nicotine addiction	hsa05033	7.38	2	GRIN2B, GRIN1
Cocaine addiction	hsa05030	7.07	2	GRIN2B, GRIN1
Amphetamine addiction	hsa05031	6.62	2	GRIN2B, GRIN1
Alcoholism	hsa05034	5.59	2	GRIN2B, GRIN1
Amyotrophic lateral sclerosis (ALS)	hsa05014	7.01	2	GRIN2B, GRIN1
Huntington's disease	hsa05016	5.17	2	GRIN2B, GRIN1
Alzheimer's disease	hsa05010	5.34	2	GRIN2B, GRIN1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
Lysine degradation (hsa00310)	-	7.01	0.048	KMT2C, SMARCA4, CTNNB1, EHMT1
Tight junction (hsa04530)	-	5.53	0.047	CTNNB1, EPB41L1, CACNG2, GRIN1, PPP2R1A, GRIN2B
Amphetamine addiction (hsa05031)	-	6.62	0.016	PPP2R1A, GRIN2B, CTNNB1, CACNG2, GRIN1
Dopaminergic synapse (hsa04728)	-	5.69	0.004	GRIN1, PPP2R5D, EPB41L1, CACNG2, CTNNB1, PPP2R1A, GRIN2B
Arrhythmogenic right ventricular cardiomyopathy (ARVC) (hsa05412)	-	6.32	0.009	GRIN1, GRIN2B, CTNNB1, EPB41L1, CACNG2
Oxytocin signaling pathway (hsa04921)	-	5.4	0.014	MEF2C, EPB41L1, CACNG2, GRIN1, PPP2R1A, GRIN2B, SMARCB1

REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME term	REACTOME term ID	IC	Number of genes with the same term	Genes
Chromatin organization	R-HSA-4839726	5.19	10	KANSL1, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, SMARCA4, ARID1A, KMT2C, ARID1B
Chromatin modifying enzymes	R-HSA-3247509	5.19	10	KANSL1, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, SMARCA4, ARID1A, KMT2C, ARID1B
Developmental Biology	R-HSA-1266738	3.48	9	SYNGAP1, PPP2R5D, CDH15, CACNG2, CTNNB1, PPP2R1A, GRIN1, MEF2C, GRIN2B
Immune System	R-HSA-168256	2.37	8	SYNGAP1, PPP2R5D, DYNC1H1, CTNNB1, PPP2R1A, GRIN1, GRIN2B, MEF2C
Signal Transduction	R-HSA-162582	1.78	8	SYNGAP1, PPP2R5D, MEF2C, CTNNB1, PPP2R1A, GRIN1, GRIN2B, SMARCA4
Innate Immune System	R-HSA-168249	3.17	7	SYNGAP1, PPP2R5D, CTNNB1, PPP2R1A, GRIN1, GRIN2B, MEF2C
Signaling by VEGF	R-HSA-194138	4.66	6	SYNGAP1, PPP2R5D, CTNNB1, PPP2R1A, GRIN1, GRIN2B
VEGFA-VEGFR2 Pathway	R-HSA-4420097	4.7	6	SYNGAP1, PPP2R5D, CTNNB1, PPP2R1A, GRIN1, GRIN2B
Signalling by NGF	R-HSA-166520	4.23	6	SYNGAP1, PPP2R5D, GRIN1, PPP2R1A, MEF2C, GRIN2B
NGF signalling via TRKA from the plasma membrane	R-HSA-187037	4.51	6	SYNGAP1, PPP2R5D, GRIN1, PPP2R1A, GRIN2B, MEF2C
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	R-HSA-2404192	4.85	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Gastrin-CREB signalling pathway via PKC and MAPK	R-HSA-881907	4.26	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
NCAM signaling for neurite out-growth	R-HSA-375165	4.9	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by Interleukins	R-HSA-449147	4.71	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
GRB2 events in ERBB2 signaling	R-HSA-1963640	5.15	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Frs2-mediated activation	R-HSA-170968	5.12	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Cytokine Signaling in Immune system	R-HSA-1280215	3.74	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
IGF1R signaling cascade	R-HSA-2428924	4.85	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
Downstream signal transduction	R-HSA-186763	4.65	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
IRS-related events triggered by IGF1R	R-HSA-2428928	4.85	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by ERBB4	R-HSA-1236394	4.7	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by Insulin receptor	R-HSA-74752	4.73	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
RAF/MAP kinase cascade	R-HSA-5673001	5.15	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by ERBB2	R-HSA-1227986	4.66	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Downstream signaling of activated FGFR1	R-HSA-5654687	4.71	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
MAPK family signaling cascades	R-HSA-5683057	4.89	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by Leptin	R-HSA-2586552	5.1	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signalling to p38 via RIT and RIN	R-HSA-187706	5.12	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
FCERI mediated MAPK activation	R-HSA-2871796	4.32	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
IRS-mediated signalling	R-HSA-112399	4.87	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
FRS-mediated FGFR2 signaling	R-HSA-5654700	5.14	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
DAP12 interactions	R-HSA-2172127	4.56	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
FRS-mediated FGFR3 signaling	R-HSA-5654706	5.14	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Downstream signaling of activated FGFR3	R-HSA-5654708	4.71	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Insulin receptor signalling cascade	R-HSA-74751	4.85	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by FGFR4	R-HSA-5654743	4.69	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by FGFR3	R-HSA-5654741	4.69	5	PPP2R1A, PPP2R5D, GRIN2B, SYNGAP1, GRIN1
Signaling by FGFR	R-HSA-190236	4.67	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Fc epsilon receptor (FCERI) signaling	R-HSA-2454202	4.03	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Interleukin-2 signaling	R-HSA-451927	5.05	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
MAPK1/MAPK3 signaling	R-HSA-5684996	5.11	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Interleukin receptor SHC signaling	R-HSA-912526	5.09	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by SCF-KIT	R-HSA-1433557	4.73	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
SHC1 events in ERBB2 signaling	R-HSA-1250196	5.15	5	PPP2R1A, PPP2R5D, GRIN2B, SYNGAP1, GRIN1
Signalling to ERKs	R-HSA-187687	5.04	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by PDGF	R-HSA-186797	4.53	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signalling to RAS	R-HSA-167044	5.08	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
DAP12 signaling	R-HSA-2424491	4.64	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
SHC1 events in EGFR signaling	R-HSA-180336	5.15	5	PPP2R1A, PPP2R5D, GRIN2B, SYNGAP1, GRIN1
Interleukin-3, 5 and GM-CSF signaling	R-HSA-512988	4.99	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Downstream signaling of activated FGFR2	R-HSA-5654696	4.71	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
SHC1 events in ERBB4 signaling	R-HSA-1250347	5.15	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by EGFR	R-HSA-177929	4.59	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
FRS-mediated FGFR1 signaling	R-HSA-5654693	5.14	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Prolonged ERK activation events	R-HSA-169893	5.11	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
FRS-mediated FGFR4 signaling	R-HSA-5654712	5.14	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
Signaling by GPCR	R-HSA-372790	2.68	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by FGFR2	R-HSA-5654738	4.68	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
GRB2 events in EGFR signaling	R-HSA-179812	5.15	5	PPP2R1A, PPP2R5D, GRIN2B, GRIN1, SYNGAP1
Signaling by FGFR1	R-HSA-5654736	4.69	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
ARMS-mediated activation	R-HSA-170984	5.12	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
SOS-mediated signalling	R-HSA-112412	5.15	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Downstream signaling of activated FGFR4	R-HSA-5654716	4.71	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
RMTs methylate histone arginines	R-HSA-3214858	7.49	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, ARID1B
Axon guidance	R-HSA-422475	3.93	5	PPP2R1A, GRIN1, GRIN2B, PPP2R5D, SYNGAP1
VEGFR2 mediated cell proliferation	R-HSA-5218921	5.07	5	PPP2R1A, GRIN2B, GRIN1, PPP2R5D, SYNGAP1
Signaling by Wnt	R-HSA-195721	4.79	4	PPP2R1A, PPP2R5D, SMARCA4, CTNNB1
TCF dependent signaling in response to WNT	R-HSA-201681	5.36	4	PPP2R1A, PPP2R5D, SMARCA4, CTNNB1
Neuronal System	R-HSA-112316	4.82	4	GRIN2B, CACNG2, EPB41L1, GRIN1
Cell Cycle, Mitotic	R-HSA-69278	4.16	4	PPP2R1A, DYNC1H1, DYRK1A, PPP2R5D
Gene Expression	R-HSA-74160	2.72	4	PPP2R1A, NR1I3, EEF1A2, GATAD2B
Cell Cycle	R-HSA-1640170	3.89	4	PPP2R1A, DYNC1H1, DYRK1A, PPP2R5D
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell	R-HSA-112314	5.85	4	GRIN1, EPB41L1, GRIN2B, CACNG2
Transmission across Chemical Synapses	R-HSA-112315	5.28	4	GRIN1, EPB41L1, GRIN2B, CACNG2
Disease	R-HSA-1643685	3.33	4	PPP2R1A, PACS1, CTNNB1, PPP2R5D
TRIF-mediated TLR3/TLR4 signaling	R-HSA-937061	6.47	3	PPP2R1A, MEF2C, PPP2R5D
ERK/MAPK targets	R-HSA-198753	8.59	3	PPP2R1A, MEF2C, PPP2R5D
Toll Like Receptor 2 (TLR2) Cascade	R-HSA-181438	6.51	3	PPP2R1A, MEF2C, PPP2R5D
Toll Like Receptor 4 (TLR4) Cascade	R-HSA-166016	6.11	3	PPP2R1A, MEF2C, PPP2R5D
Signaling by Rho GTPases	R-HSA-194315	4.43	3	PPP2R1A, PPP2R5D, CTNNB1
MyD88 cascade initiated on plasma membrane	R-HSA-975871	6.73	3	PPP2R1A, MEF2C, PPP2R5D
Cell-Cell communication	R-HSA-1500931	5.87	3	KIRREL3, CDH15, CTNNB1
RHO GTPase Effectors	R-HSA-195258	4.94	3	PPP2R1A, PPP2R5D, CTNNB1
Metabolism	R-HSA-1430728	2.34	3	PPP2R1A, COL4A3BP, PPP2R5D
CDO in myogenesis	R-HSA-375170	8.12	3	MEF2C, CDH15, CTNNB1
disassembly of the destruction complex and recruitment of AXIN to the membrane	R-HSA-4641262	8.03	3	PPP2R1A, PPP2R5D, CTNNB1
Adaptive Immune System	R-HSA-1280218	3.19	3	PPP2R1A, DYNC1H1, PPP2R5D
T41 mutants of beta-catenin aren't phosphorylated	R-HSA-5358752	9.08	3	PPP2R1A, CTNNB1, PPP2R5D
S45 mutants of beta-catenin aren't phosphorylated	R-HSA-5358751	9.08	3	PPP2R1A, CTNNB1, PPP2R5D
Toll Like Receptor 10 (TLR10) Cascade	R-HSA-168142	6.73	3	PPP2R1A, MEF2C, PPP2R5D
Organelle biogenesis and maintenance	R-HSA-1852241	4.63	3	PPP2R1A, DYNC1H1, MEF2C
Toll Like Receptor 3 (TLR3) Cascade	R-HSA-168164	6.47	3	PPP2R1A, MEF2C, PPP2R5D
Beta-catenin phosphorylation cascade	R-HSA-196299	8.89	3	PPP2R1A, PPP2R5D, CTNNB1
Toll-Like Receptors Cascades	R-HSA-168898	5.91	3	PPP2R1A, MEF2C, PPP2R5D
Nuclear Events (kinase and transcription factor activation)	R-HSA-198725	8.4	3	PPP2R1A, MEF2C, PPP2R5D
MyD88-independent TLR3/TLR4 cascade	R-HSA-166166	6.47	3	PPP2R1A, MEF2C, PPP2R5D
Myogenesis	R-HSA-525793	8.12	3	MEF2C, CDH15, CTNNB1
Toll Like Receptor TLR6:TLR2 Cascade	R-HSA-168188	6.56	3	PPP2R1A, MEF2C, PPP2R5D
Diseases of signal transduction	R-HSA-5663202	4.89	3	PPP2R1A, PPP2R5D, CTNNB1
Toll Like Receptor 7/8 (TLR7/8) Cascade	R-HSA-168181	6.68	3	PPP2R1A, MEF2C, PPP2R5D
Toll Like Receptor TLR1:TLR2 Cascade	R-HSA-168179	6.51	3	PPP2R1A, MEF2C, PPP2R5D
MAPK targets/ Nuclear events mediated by MAP kinases	R-HSA-450282	8.08	3	PPP2R1A, MEF2C, PPP2R5D
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	R-HSA-4839743	9.08	3	PPP2R1A, PPP2R5D, CTNNB1
MAP kinase activation in TLR cascade	R-HSA-450294	7.28	3	PPP2R1A, MEF2C, PPP2R5D
misspliced GSK3beta mutants stabilize beta-catenin	R-HSA-5339716	9.08	3	PPP2R1A, PPP2R5D, CTNNB1
S33 mutants of beta-catenin aren't phosphorylated	R-HSA-5358747	9.08	3	PPP2R1A, PPP2R5D, CTNNB1
S37 mutants of beta-catenin aren't phosphorylated	R-HSA-5358749	9.08	3	PPP2R1A, CTNNB1, PPP2R5D
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	R-HSA-975138	6.72	3	PPP2R1A, MEF2C, PPP2R5D
Signaling by WNT in cancer	R-HSA-4791275	7.89	3	PPP2R1A, CTNNB1, PPP2R5D
Toll Like Receptor 5 (TLR5) Cascade	R-HSA-168176	6.73	3	PPP2R1A, MEF2C, PPP2R5D
MyD88 dependent cascade initiated on endosome	R-HSA-975155	6.68	3	PPP2R1A, MEF2C, PPP2R5D
MyD88:Mal cascade initiated on plasma membrane	R-HSA-166058	6.56	3	PPP2R1A, MEF2C, PPP2R5D
Degradation of beta-catenin by the destruction complex	R-HSA-195253	6.64	3	PPP2R1A, CTNNB1, PPP2R5D
Activated TLR4 signalling	R-HSA-166054	6.27	3	PPP2R1A, MEF2C, PPP2R5D
Toll Like Receptor 9 (TLR9) Cascade	R-HSA-168138	6.62	3	PPP2R1A, MEF2C, PPP2R5D
CREB phosphorylation through the activation of CaMKII	R-HSA-442729	9.08	2	GRIN2B, GRIN1
Glucose metabolism	R-HSA-70326	6.77	2	PPP2R1A, PPP2R5D
Separation of Sister Chromatids	R-HSA-2467813	5.55	2	PPP2R1A, PPP2R5D
Post NMDA receptor activation events	R-HSA-438064	7.85	2	GRIN2B, GRIN1
Trafficking of AMPA receptors	R-HSA-399719	8.08	2	EPB41L1, CACNG2
Unblocking of NMDA receptor, glutamate binding and activation	R-HSA-438066	8.89	2	GRIN2B, GRIN1
Loss of Nlp from mitotic centrosomes	R-HSA-380259	7.03	2	PPP2R1A, DYNC1H1
Adherens junctions interactions	R-HSA-418990	7.98	2	CDH15, CTNNB1
Assembly of the primary cilium	R-HSA-5617833	5.44	2	PPP2R1A, DYNC1H1
CREB phosphorylation through the activation of Ras	R-HSA-442742	8.23	2	GRIN2B, GRIN1
RAF activation	R-HSA-5673000	8.34	2	PPP2R1A, PPP2R5D
Recruitment of mitotic centrosome proteins and complexes	R-HSA-380270	6.68	2	PPP2R1A, DYNC1H1
HATs acetylate histones	R-HSA-3214847	6.23	2	KAT6A, KANSL1
DARPP-32 events	R-HSA-180024	8.4	2	PPP2R1A, PPP2R5D
Resolution of Sister Chromatid Cohesion	R-HSA-2500257	6.18	2	PPP2R1A, PPP2R5D
Metabolism of carbohydrates	R-HSA-71387	4.93	2	PPP2R1A, PPP2R5D
Mitotic Metaphase and Anaphase	R-HSA-2555396	5.45	2	PPP2R1A, PPP2R5D
Ras activation uopn Ca2+ infux through NMDA receptor	R-HSA-442982	8.89	2	GRIN2B, GRIN1
CTLA4 inhibitory signaling	R-HSA-389513	8.52	2	PPP2R1A, PPP2R5D
Cell-cell junction organization	R-HSA-421270	7.03	2	CDH15, CTNNB1
AXIN missense mutants destabilize the destruction complex	R-HSA-5467340	9.18	2	PPP2R1A, PPP2R5D
AXIN mutants destabilize the destruction complex, activating WNT signaling	R-HSA-4839735	9.18	2	PPP2R1A, PPP2R5D
Platelet homeostasis	R-HSA-418346	6.68	2	PPP2R1A, PPP2R5D
Platelet sensitization by LDL	R-HSA-432142	8.89	2	PPP2R1A, PPP2R5D
Costimulation by the CD28 family	R-HSA-388841	6.56	2	PPP2R1A, PPP2R5D
Hemostasis	R-HSA-109582	3.98	2	PPP2R1A, PPP2R5D
G2/M Transition	R-HSA-69275	6.06	2	PPP2R1A, DYNC1H1
Mitotic G1-G1/S phases	R-HSA-453279	5.91	2	PPP2R1A, DYRK1A
RHO GTPases Activate Formins	R-HSA-5663220	6.01	2	PPP2R1A, PPP2R5D
PKMTs methylate histone lysines	R-HSA-3214841	7.66	2	KMT2C, EHMT1
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	R-HSA-399721	8.08	2	EPB41L1, CACNG2
Loss of proteins required for interphase microtubule organization from the centrosome	R-HSA-380284	7.03	2	PPP2R1A, DYNC1H1
Centrosome maturation	R-HSA-380287	6.68	2	PPP2R1A, DYNC1H1
Mitotic G2-G2/M phases	R-HSA-453274	6.04	2	PPP2R1A, DYNC1H1
Metabolism of proteins	R-HSA-392499	3.41	2	EEF1A2, CTNNB1
Integration of energy metabolism	R-HSA-163685	6.24	2	PPP2R1A, PPP2R5D
M Phase	R-HSA-68886	4.87	2	PPP2R1A, PPP2R5D
Anchoring of the basal body to the plasma membrane	R-HSA-5620912	6.51	2	PPP2R1A, DYNC1H1
Glycolysis	R-HSA-70171	8.03	2	PPP2R1A, PPP2R5D
Mitotic Anaphase	R-HSA-68882	5.46	2	PPP2R1A, PPP2R5D
Activation of NMDA receptor upon glutamate binding and postsynaptic events	R-HSA-442755	7.7	2	GRIN2B, GRIN1
EPH-Ephrin signaling	R-HSA-2682334	6.43	2	GRIN2B, GRIN1
truncations of AMER1 destabilize the destruction complex	R-HSA-5467348	9.18	2	PPP2R1A, PPP2R5D
Negative regulation of MAPK pathway	R-HSA-5675221	7.66	2	PPP2R1A, PPP2R5D
formation of the beta-catenin:TCF transactivating complex	R-HSA-201722	7.18	2	SMARCA4, CTNNB1
Cell junction organization	R-HSA-446728	6.51	2	CDH15, CTNNB1
PP2A-mediated dephosphorylation of key metabolic factors	R-HSA-163767	10.18	2	PPP2R1A, PPP2R5D
AMER1 mutants destabilize the destruction complex	R-HSA-4839748	9.18	2	PPP2R1A, PPP2R5D
Opioid Signalling	R-HSA-111885	6.64	2	PPP2R1A, PPP2R5D
EPHB-mediated forward signaling	R-HSA-3928662	7.62	2	GRIN2B, GRIN1
truncated APC mutants destabilize the destruction complex	R-HSA-4839744	9.18	2	PPP2R1A, PPP2R5D
Regulation of PLK1 Activity at G2/M Transition	R-HSA-2565942	6.66	2	PPP2R1A, DYNC1H1
ERKs are inactivated	R-HSA-202670	9.4	2	PPP2R1A, PPP2R5D
APC truncation mutants have impaired AXIN binding	R-HSA-5467337	9.18	2	PPP2R1A, PPP2R5D
Mitotic Prometaphase	R-HSA-68877	6.08	2	PPP2R1A, PPP2R5D

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
ERK/MAPK targets (R-HSA-198753)	-	8.59	0.01	PPP2R1A, MEF2C, PPP2R5D
Trafficking of AMPA receptors (R-HSA-399719)	-	8.08	0.002	GRIN2B, CACNG2, EPB41L1, GRIN1
Mitochondrial biogenesis (R-HSA-1592230)	NEW	7.34	0.008	MEF2C, NR1I3, SMARCB1, SMARCA4, CTNNB1
CDO in myogenesis (R-HSA-375170)	-	8.12	0.027	MEF2C, CDH15, CTNNB1
Cell Cycle (R-HSA-1640170)	-	3.89	0.022	KANSL1, COL4A3BP, PPP2R5D, CTCF, DYNC1H1, SMARCB1, PACS1, DYRK1A, PPP2R1A, KMT2C, SMARCA4
T41 mutants of beta-catenin aren't phosphorylated (R-HSA-5358752)	-	9.08	0.006	PPP2R1A, CTNNB1, PPP2R5D
S45 mutants of beta-catenin aren't phosphorylated (R-HSA-5358751)	-	9.08	0.006	PPP2R1A, CTNNB1, PPP2R5D
Beta-catenin phosphorylation cascade (R-HSA-196299)	-	8.89	0.005	PPP2R1A, PPP2R5D, CTNNB1
Nuclear Events (kinase and transcription factor activation) (R-HSA-198725)	-	8.4	0.029	PPP2R1A, MEF2C, PPP2R5D
Myogenesis (R-HSA-525793)	-	8.12	0.027	MEF2C, CDH15, CTNNB1
disassembly of the destruction complex and recruitment of AXIN to the membrane (R-HSA-4641262)	-	8.03	0.033	PPP2R1A, PPP2R5D, CTNNB1
Signalling to RAS (R-HSA-167044)	-	5.08	0.032	SYNGAP1, PPP2R5D, SMARCE1, CTNNB1, PPP2R1A, GRIN1, GRIN2B, MEF2C
MAPK targets/ Nuclear events mediated by MAP kinases (R-HSA-450282)	-	8.08	0.03	PPP2R1A, MEF2C, PPP2R5D
Chromatin modifying enzymes (R-HSA-3247509)	-	5.19	0.0	KANSL1, SMARCA4, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, CTNNB1, KMT2C, ARID1A, ARID1B
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity (R-HSA-399721)	-	8.08	0.002	GRIN1, EPB41L1, GRIN2B, CACNG2
RHO GTPase Effectors (R-HSA-195258)	-	4.94	0.002	PPP2R5D, ARID1A, DYNC1H1, EPB41L1, CTNNB1, PPP2R1A, GRIN1, GRIN2B, SMARCB1, SMARCA4
misspliced GSK3beta mutants stabilize beta-catenin (R-HSA-5339716)	-	9.08	0.006	PPP2R1A, CTNNB1, PPP2R5D
S33 mutants of beta-catenin aren't phosphorylated (R-HSA-5358747)	-	9.08	0.006	PPP2R1A, CTNNB1, PPP2R5D
S37 mutants of beta-catenin aren't phosphorylated (R-HSA-5358749)	-	9.08	0.006	PPP2R1A, PPP2R5D, CTNNB1
Signalling to ERKs (R-HSA-187687)	-	5.04	0.041	PPP2R5D, SYNGAP1, SMARCE1, CTNNB1, PPP2R1A, GRIN1, GRIN2B, MEF2C
Signaling by WNT in cancer (R-HSA-4791275)	-	7.89	0.043	PPP2R1A, CTNNB1, PPP2R5D
Chromatin organization (R-HSA-4839726)	-	5.19	0.0	KANSL1, SMARCA4, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, CTNNB1, ARID1A, KMT2C, ARID1B
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex (R-HSA-4839743)	-	9.08	0.006	PPP2R1A, CTNNB1, PPP2R5D
RMTs methylate histone arginines (R-HSA-3214858)	-	7.49	0.0	SMARCE1, SMARCB1, ARID1B, ARID1A, SMARCA4

GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
binding (GO:0005488)	0.18	43	KIF1A, GATAD2B, PPP2R5D, AHDC1, PACS1, POGZ, KIRREL3, GRIN1, CACNG2, ARID1A, AUTS2, ZMYND11, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, SETD5, SMARCE1, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, KANSL1, CDH15, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, SETBP1, NR1I3, EHMT1, PURA, EPB41L1, DYRK1A, MEF2C, COL4A3BP, ARID1B
protein binding (GO:0005515)	0.46	37	KIF1A, PPP2R5D, SMARCB1, CACNG2, PACS1, SETD5, KIRREL3, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, CTNNB1, PURA, GRIN2B, EPB41L1, KANSL1, COL4A3BP, DYNC1H1, DEAF1, ZBTB18, PPP2R1A, SETBP1, SMARCA4, EHMT1, GATAD2B, CDH15, DYRK1A, MEF2C, ARID1B
organic cyclic compound binding (GO:0097159)	1.05	28	KIF1A, CTCF, AHDC1, GATAD2B, ARID1A, KMT2C, SMARCE1, ADNP, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, DEAF1, DYRK1A, MBD5, DYNC1H1, SMARCB1, NR1I3, ZBTB18, MYT1L, SETBP1, PURA, SMARCA4, MEF2C, ARID1B
heterocyclic compound binding (GO:1901363)	1.06	28	KIF1A, CTCF, AHDC1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, DEAF1, DYRK1A, MBD5, DYNC1H1, SMARCB1, NR1I3, ZBTB18, MYT1L, KMT2C, PURA, SMARCA4, MEF2C, ARID1B
nucleic acid binding (GO:0003676)	1.44	26	CTCF, AHDC1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, DEAF1, MBD5, DYNC1H1, SMARCB1, NR1I3, ZBTB18, MYT1L, KMT2C, PURA, SMARCA4, MEF2C, ARID1B
DNA binding (GO:0003677)	1.92	23	CTCF, AHDC1, PURA, ARID1A, SETBP1, SMARCE1, ADNP, POGZ, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, MBD5, DEAF1, NR1I3, ZBTB18, MYT1L, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
cation binding (GO:0043169)	1.4	16	ADNP, GATAD2B, EHMT1, KAT6A, DEAF1, NR1I3, ZBTB18, ZMYND11, CHAMP1, CTCF, POGZ, CDH15, MYT1L, GRIN1, KMT2C, GRIN2B
metal ion binding (GO:0046872)	1.41	16	NR1I3, GATAD2B, CTCF, CHAMP1, DEAF1, ADNP, ZBTB18, ZMYND11, EHMT1, KAT6A, POGZ, CDH15, MYT1L, GRIN1, GRIN2B, KMT2C
ion binding (GO:0043167)	1.36	16	NR1I3, GATAD2B, CTCF, CHAMP1, DEAF1, ADNP, ZBTB18, ZMYND11, EHMT1, KAT6A, POGZ, CDH15, MYT1L, GRIN1, KMT2C, GRIN2B
catalytic activity (GO:0003824)	1.05	14	KANSL1, KIF1A, DYRK1A, PPP2R5D, DYNC1H1, EEF1A2, KAT6A, SMARCE1, EHMT1, COL4A3BP, PPP2R1A, KMT2C, SMARCA4, DPP6
chromatin binding (GO:0003682)	3.64	12	ZMYND11, ADNP, CTNNB1, MBD5, CTCF, SMARCB1, GATAD2B, SMARCE1, AUTS2, MEF2C, ARID1A, SMARCA4
macromolecular complex binding (GO:0044877)	2.61	12	ZMYND11, ADNP, CTNNB1, MBD5, CTCF, SMARCB1, GATAD2B, SMARCE1, AUTS2, MEF2C, ARID1A, SMARCA4
transcription regulatory region DNA binding (GO:0044212)	3.03	11	ZMYND11, NR1I3, SMARCA4, CTCF, SMARCB1, PURA, SMARCE1, SOX11, GATAD2B, CTNNB1, MEF2C
sequence-specific DNA binding (GO:0043565)	2.79	11	ZMYND11, NR1I3, GATAD2B, CTCF, SMARCB1, PURA, SMARCE1, SOX11, ZBTB18, SMARCA4, MEF2C
regulatory region DNA binding (GO:0000975)	3.03	11	ZMYND11, NR1I3, SMARCA4, CTCF, SMARCB1, PURA, SMARCE1, SOX11, GATAD2B, CTNNB1, MEF2C
regulatory region nucleic acid binding (GO:0001067)	3.03	11	ZMYND11, NR1I3, SMARCA4, CTCF, SMARCB1, PURA, SMARCE1, SOX11, GATAD2B, CTNNB1, MEF2C
transcription cofactor activity (GO:0003712)	3.44	11	ZMYND11, NR1I3, SMARCA4, CTCF, SMARCB1, SMARCE1, KAT6A, SOX11, CTNNB1, ARID1A, ARID1B
transcription factor activity, transcription factor binding (GO:0000989)	3.36	11	ZMYND11, NR1I3, SMARCA4, CTCF, SMARCB1, SMARCE1, KAT6A, SOX11, CTNNB1, ARID1A, ARID1B
transcription factor activity, protein binding (GO:0000988)	3.35	11	SMARCE1, NR1I3, SMARCA4, CTCF, SMARCB1, ZMYND11, KAT6A, SOX11, CTNNB1, ARID1A, ARID1B
double-stranded DNA binding (GO:0003690)	3.09	11	ZMYND11, NR1I3, CTNNB1, CTCF, SMARCB1, PURA, SMARCE1, SOX11, GATAD2B, SMARCA4, MEF2C
transcription factor activity, sequence-specific DNA binding (GO:0003700)	2.65	10	MYT1L, CTCF, DEAF1, NR1I3, ZBTB18, SOX11, GATAD2B, CTNNB1, PURA, MEF2C
sequence-specific double-stranded DNA binding (GO:1990837)	3.2	10	ZMYND11, NR1I3, CTCF, SMARCB1, PURA, SMARCE1, SOX11, GATAD2B, SMARCA4, MEF2C
nucleic acid binding transcription factor activity (GO:0001071)	2.65	10	NR1I3, CTCF, DEAF1, MYT1L, ZBTB18, SOX11, GATAD2B, CTNNB1, PURA, MEF2C
transition metal ion binding (GO:0046914)	2.48	10	NR1I3, CTCF, KAT6A, ADNP, GATAD2B, ZMYND11, EHMT1, MYT1L, KMT2C, GRIN2B
transcription regulatory region sequence-specific DNA binding (GO:0000976)	3.24	9	ZMYND11, NR1I3, CTCF, SMARCB1, GATAD2B, SMARCE1, SOX11, SMARCA4, MEF2C
zinc ion binding (GO:0008270)	2.66	9	NR1I3, CTCF, KAT6A, MYT1L, GATAD2B, ZMYND11, EHMT1, GRIN2B, KMT2C
RNA polymerase II regulatory region DNA binding (GO:0001012)	3.36	9	ZMYND11, NR1I3, CTCF, SMARCB1, GATAD2B, SMARCE1, SOX11, SMARCA4, MEF2C
RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977)	3.37	9	ZMYND11, NR1I3, CTCF, SMARCB1, GATAD2B, SMARCE1, SOX11, SMARCA4, MEF2C
transcription coactivator activity (GO:0003713)	4.04	9	NR1I3, SMARCA4, SMARCB1, SMARCE1, KAT6A, SOX11, CTNNB1, ARID1A, ARID1B
hydrolase activity (GO:0016787)	1.9	7	KIF1A, PPP2R5D, DYNC1H1, EEF1A2, SMARCA4, PPP2R1A, DPP6
transferase activity (GO:0016740)	1.95	7	KANSL1, COL4A3BP, KAT6A, SMARCE1, EHMT1, DYRK1A, KMT2C
molecular function regulator (GO:0098772)	2.51	7	SYNGAP1, PPP2R5D, CACNG2, GRIN1, PPP2R1A, GRIN2B, DPP6
RNA binding (GO:0003723)	2.36	7	DYNC1H1, EEF1A2, PURA, SMARCE1, SOX11, MEF2C, KMT2C
transcription factor binding (GO:0008134)	3.46	6	CTNNB1, SMARCB1, PURA, KAT6A, SMARCA4, MEF2C
enzyme binding (GO:0019899)	2.27	6	CTNNB1, SYNGAP1, EEF1A2, GRIN1, MEF2C, SMARCA4
enhancer sequence-specific DNA binding (GO:0001158)	5.36	6	SMARCB1, GATAD2B, SMARCE1, SOX11, SMARCA4, MEF2C
protein complex binding (GO:0032403)	3.09	6	CTNNB1, SMARCB1, GATAD2B, SMARCE1, SMARCA4, ARID1A
core promoter proximal region DNA binding (GO:0001159)	3.82	6	CTCF, SMARCB1, GATAD2B, SMARCE1, SMARCA4, MEF2C
core promoter proximal region sequence-specific DNA binding (GO:0000987)	3.83	6	CTCF, SMARCB1, GATAD2B, SMARCE1, SMARCA4, MEF2C
RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978)	3.88	6	CTCF, SMARCB1, GATAD2B, SMARCE1, SMARCA4, MEF2C
receptor binding (GO:0005102)	2.43	6	CTNNB1, SMARCE1, CACNG2, SMARCA4, GRIN1, ARID1A
enhancer binding (GO:0035326)	5.21	6	SMARCB1, GATAD2B, SMARCE1, SOX11, SMARCA4, MEF2C
nucleosome binding (GO:0031491)	5.95	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, GATAD2B
structure-specific DNA binding (GO:0043566)	4.98	5	SMARCE1, SMARCB1, SMARCA4, GATAD2B, CTCF
chromatin DNA binding (GO:0031490)	5.37	5	SMARCE1, SMARCB1, SMARCA4, GATAD2B, CTCF
carbohydrate derivative binding (GO:0097367)	2.03	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
RNA polymerase II transcription factor activity, sequence-specific DNA binding (GO:0000981)	3.29	5	MEF2C, NR1I3, SOX11, CTCF, PURA
nucleotide binding (GO:0000166)	1.96	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
small molecule binding (GO:0036094)	1.89	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
purine ribonucleoside triphosphate binding (GO:0035639)	2.22	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
ribonucleotide binding (GO:0032553)	2.19	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
purine nucleoside binding (GO:0001883)	2.22	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
ribonucleoside binding (GO:0032549)	2.22	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
purine ribonucleotide binding (GO:0032555)	2.2	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
purine nucleotide binding (GO:0017076)	2.19	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
nucleoside binding (GO:0001882)	2.21	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
purine ribonucleoside binding (GO:0032550)	2.22	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
nucleoside phosphate binding (GO:1901265)	1.96	5	DYNC1H1, EEF1A2, KIF1A, SMARCA4, DYRK1A
RNA polymerase II distal enhancer sequence-specific DNA binding (GO:0000980)	5.58	5	SMARCE1, MEF2C, SMARCB1, SMARCA4, GATAD2B
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818)	3.03	4	DYNC1H1, EEF1A2, KIF1A, SMARCA4
substrate-specific transporter activity (GO:0022892)	2.72	4	GRIN1, GRIN2B, CACNG2, COL4A3BP
core promoter binding (GO:0001047)	4.71	4	MEF2C, SOX11, SMARCB1, SMARCA4
cytoskeletal protein binding (GO:0008092)	3.02	4	EPB41L1, KIF1A, ADNP, DYRK1A
transporter activity (GO:0005215)	2.57	4	GRIN2B, CACNG2, COL4A3BP, GRIN1
nucleoside-triphosphatase activity (GO:0017111)	3.09	4	DYNC1H1, EEF1A2, KIF1A, SMARCA4
adenyl nucleotide binding (GO:0030554)	2.4	4	DYNC1H1, KIF1A, SMARCA4, DYRK1A
hydrolase activity, acting on acid anhydrides (GO:0016817)	3.03	4	DYNC1H1, EEF1A2, KIF1A, SMARCA4
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding (GO:0001228)	3.98	4	NR1I3, SOX11, MEF2C, CTCF
pyrophosphatase activity (GO:0016462)	3.04	4	DYNC1H1, EEF1A2, KIF1A, SMARCA4
nucleosomal DNA binding (GO:0031492)	6.37	4	SMARCE1, SMARCB1, SMARCA4, GATAD2B
adenyl ribonucleotide binding (GO:0032559)	2.41	4	DYNC1H1, KIF1A, SMARCA4, DYRK1A
signal transducer activity (GO:0004871)	2.28	4	GRIN2B, NR1I3, GRIN1, CTNNB1
core promoter sequence-specific DNA binding (GO:0001046)	5.12	4	MEF2C, SOX11, SMARCB1, SMARCA4
ATP binding (GO:0005524)	2.43	4	DYNC1H1, KIF1A, SMARCA4, DYRK1A
signaling receptor activity (GO:0038023)	2.49	3	GRIN2B, NR1I3, GRIN1
molecular transducer activity (GO:0060089)	2.32	3	NR1I3, GRIN2B, GRIN1
receptor activity (GO:0004872)	2.32	3	NR1I3, GRIN2B, GRIN1
ATPase activity (GO:0016887)	3.65	3	DYNC1H1, KIF1A, SMARCA4
enzyme regulator activity (GO:0030234)	2.85	3	PPP2R1A, PPP2R5D, SYNGAP1
N-acetyltransferase activity (GO:0008080)	5.27	3	SMARCE1, KAT6A, KANSL1
transcription corepressor activity (GO:0003714)	4.33	3	ZMYND11, CTCF, SMARCA4
transmembrane transporter activity (GO:0022857)	2.82	3	GRIN2B, CACNG2, GRIN1
transferase activity, transferring acyl groups (GO:0016746)	4.2	3	SMARCE1, KANSL1, KAT6A
transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747)	4.37	3	SMARCE1, KAT6A, KANSL1
N-acyltransferase activity (GO:0016410)	5.08	3	SMARCE1, KANSL1, KAT6A
passive transmembrane transporter activity (GO:0022803)	3.6	3	GRIN2B, CACNG2, GRIN1
poly(A) RNA binding (GO:0044822)	2.69	3	DYNC1H1, KMT2C, PURA
ion channel activity (GO:0005216)	3.71	3	GRIN2B, CACNG2, GRIN1
glutamate receptor binding (GO:0035254)	6.13	3	CACNG2, GRIN1, CTNNB1
protein kinase binding (GO:0019901)	3.44	3	EEF1A2, SYNGAP1, CTNNB1
kinase binding (GO:0019900)	3.32	3	EEF1A2, CTNNB1, SYNGAP1
protein domain specific binding (GO:0019904)	3.32	3	EHMT1, MEF2C, SYNGAP1
substrate-specific transmembrane transporter activity (GO:0022891)	2.9	3	GRIN2B, CACNG2, GRIN1
substrate-specific channel activity (GO:0022838)	3.67	3	GRIN2B, CACNG2, GRIN1
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0000982)	3.94	3	MEF2C, SOX11, CTCF
ion transmembrane transporter activity (GO:0015075)	3.04	3	GRIN2B, CACNG2, GRIN1
acetyltransferase activity (GO:0016407)	5.1	3	SMARCE1, KAT6A, KANSL1
channel activity (GO:0015267)	3.6	3	GRIN2B, CACNG2, GRIN1
gated channel activity (GO:0022836)	3.96	3	GRIN2B, CACNG2, GRIN1
protein dimerization activity (GO:0046983)	2.72	3	PPP2R1A, MEF2C, GRIN1
protein heterodimerization activity (GO:0046982)	3.64	3	PPP2R1A, MEF2C, GRIN1
p53 binding (GO:0002039)	5.53	3	EHMT1, SMARCB1, SMARCA4
histone-lysine N-methyltransferase activity (GO:0018024)	5.93	2	KMT2C, EHMT1
histone binding (GO:0042393)	4.72	2	ZMYND11, SMARCA4
cation channel activity (GO:0005261)	4.04	2	CACNG2, GRIN1
activating transcription factor binding (GO:0033613)	5.68	2	MEF2C, CTNNB1
calcium channel activity (GO:0005262)	5.03	2	CACNG2, GRIN1
carboxylic acid binding (GO:0031406)	4.64	2	GRIN2B, GRIN1
phosphatase regulator activity (GO:0019208)	5.26	2	PPP2R1A, PPP2R5D
androgen receptor binding (GO:0050681)	6.07	2	SMARCA4, CTNNB1
RNA polymerase I regulatory region DNA binding (GO:0001013)	7.54	2	SMARCB1, SMARCA4
peptide-lysine-N-acetyltransferase activity (GO:0061733)	5.68	2	KANSL1, KAT6A
protein-lysine N-methyltransferase activity (GO:0016279)	5.71	2	KMT2C, EHMT1
phosphoric ester hydrolase activity (GO:0042578)	3.82	2	PPP2R1A, PPP2R5D
transcription factor activity, RNA polymerase II transcription factor binding (GO:0001076)	4.84	2	SOX11, SMARCA4
protein methyltransferase activity (GO:0008276)	5.33	2	KMT2C, EHMT1
extracellular-glutamate-gated ion channel activity (GO:0005234)	6.74	2	GRIN2B, GRIN1
peptide N-acetyltransferase activity (GO:0034212)	5.55	2	KAT6A, KANSL1
protein phosphatase type 2A regulator activity (GO:0008601)	6.69	2	PPP2R1A, PPP2R5D
Ras guanyl-nucleotide exchange factor activity (GO:0005088)	4.31	2	GRIN2B, GRIN1
methyltransferase activity (GO:0008168)	4.35	2	EHMT1, KMT2C
ion channel binding (GO:0044325)	5.02	2	PACS1, CTNNB1
amino acid binding (GO:0016597)	5.71	2	GRIN2B, GRIN1
ionotropic glutamate receptor activity (GO:0004970)	6.79	2	GRIN2B, GRIN1
glycine binding (GO:0016594)	7.1	2	GRIN2B, GRIN1
anion binding (GO:0043168)	4.17	2	GRIN2B, GRIN1
calcium ion transmembrane transporter activity (GO:0015085)	4.89	2	CACNG2, GRIN1
transcriptional repressor activity, RNA polymerase II transcription factor binding (GO:0001191)	5.28	2	SOX11, SMARCA4
ligand-gated channel activity (GO:0022834)	4.8	2	GRIN2B, GRIN1
RNA polymerase II transcription cofactor activity (GO:0001104)	5.22	2	SOX11, SMARCA4
extracellular ligand-gated ion channel activity (GO:0005230)	5.42	2	GRIN2B, GRIN1
NMDA glutamate receptor activity (GO:0004972)	7.66	2	GRIN2B, GRIN1
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding (GO:0003705)	5.23	2	MEF2C, PURA
histone acetyltransferase activity (GO:0004402)	5.7	2	KAT6A, KANSL1
ligand-gated ion channel activity (GO:0015276)	4.8	2	GRIN2B, GRIN1
divalent inorganic cation transmembrane transporter activity (GO:0072509)	4.62	2	CACNG2, GRIN1
transferase activity, transferring one-carbon groups (GO:0016741)	4.3	2	EHMT1, KMT2C
calcium ion binding (GO:0005509)	3.17	2	CDH15, GRIN1
protein kinase activity (GO:0004672)	3.27	2	COL4A3BP, DYRK1A
channel regulator activity (GO:0016247)	4.88	2	CACNG2, DPP6
metal ion transmembrane transporter activity (GO:0046873)	3.71	2	CACNG2, GRIN1
motor activity (GO:0003774)	4.81	2	DYNC1H1, KIF1A
microtubule motor activity (GO:0003777)	5.34	2	DYNC1H1, KIF1A
voltage-gated cation channel activity (GO:0022843)	4.83	2	CACNG2, GRIN1
Tat protein binding (GO:0030957)	7.66	2	SMARCB1, SMARCA4
tubulin binding (GO:0015631)	4.1	2	ADNP, KIF1A
steroid hormone receptor binding (GO:0035258)	5.32	2	SMARCA4, CTNNB1
protein phosphatase regulator activity (GO:0019888)	5.41	2	PPP2R1A, PPP2R5D
amide binding (GO:0033218)	4.14	2	ADNP, COL4A3BP
RNA polymerase I CORE element sequence-specific DNA binding (GO:0001164)	7.66	2	SMARCB1, SMARCA4
excitatory extracellular ligand-gated ion channel activity (GO:0005231)	5.73	2	GRIN2B, GRIN1
nuclear hormone receptor binding (GO:0035257)	4.7	2	SMARCA4, CTNNB1
RNA polymerase I regulatory region sequence-specific DNA binding (GO:0001163)	7.66	2	SMARCB1, SMARCA4
ionotropic glutamate receptor binding (GO:0035255)	6.56	2	CACNG2, CTNNB1
SMAD binding (GO:0046332)	5.45	2	PURA, CTNNB1
transmitter-gated ion channel activity (GO:0022824)	6.41	2	GRIN2B, GRIN1
N-methyltransferase activity (GO:0008170)	5.26	2	EHMT1, KMT2C
S-adenosylmethionine-dependent methyltransferase activity (GO:0008757)	4.81	2	KMT2C, EHMT1
hydrolase activity, acting on ester bonds (GO:0016788)	3.1	2	PPP2R1A, PPP2R5D
phosphatase activity (GO:0016791)	4.11	2	PPP2R1A, PPP2R5D
hormone receptor binding (GO:0051427)	4.57	2	SMARCA4, CTNNB1
cation transmembrane transporter activity (GO:0008324)	3.32	2	CACNG2, GRIN1
ligand-dependent nuclear receptor binding (GO:0016922)	6.6	2	SMARCE1, ARID1A
transcriptional activator activity, RNA polymerase II transcription factor binding (GO:0001190)	5.77	2	SOX11, SMARCA4
inorganic cation transmembrane transporter activity (GO:0022890)	3.49	2	CACNG2, GRIN1
neurotransmitter receptor activity (GO:0030594)	5.5	2	GRIN2B, GRIN1
histone methyltransferase activity (GO:0042054)	5.68	2	EHMT1, KMT2C
protein N-terminus binding (GO:0047485)	5.11	2	SMARCE1, SMARCA4
RNA polymerase II transcription coactivator activity (GO:0001105)	6.15	2	SOX11, SMARCA4
phosphotransferase activity, alcohol group as acceptor (GO:0016773)	3.08	2	COL4A3BP, DYRK1A
transferase activity, transferring phosphorus-containing groups (GO:0016772)	2.77	2	COL4A3BP, DYRK1A
translation factor activity, RNA binding (GO:0008135)	5.07	2	EEF1A2, SOX11
kinase activity (GO:0016301)	2.93	2	COL4A3BP, DYRK1A
glutamate receptor activity (GO:0008066)	6.44	2	GRIN2B, GRIN1
phosphoprotein phosphatase activity (GO:0004721)	4.55	2	PPP2R1A, PPP2R5D
voltage-gated channel activity (GO:0022832)	4.49	2	CACNG2, GRIN1
transmembrane signaling receptor activity (GO:0004888)	2.57	2	GRIN2B, GRIN1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (GO:0001077)	4.31	2	MEF2C, SOX11
transmitter-gated channel activity (GO:0022835)	6.41	2	GRIN2B, GRIN1
protein serine/threonine phosphatase activity (GO:0004722)	5.58	2	PPP2R1A, PPP2R5D
lysine N-methyltransferase activity (GO:0016278)	5.7	2	KMT2C, EHMT1
voltage-gated ion channel activity (GO:0005244)	4.49	2	CACNG2, GRIN1
guanyl-nucleotide exchange factor activity (GO:0005085)	4.02	2	GRIN2B, GRIN1
transmembrane receptor activity (GO:0099600)	2.53	2	GRIN2B, GRIN1
transcriptional repressor activity, RNA polymerase II activating transcription factor binding (GO:0098811)	5.77	2	SOX11, SMARCA4

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
RNA polymerase II regulatory region DNA binding (GO:0001012)	-	3.36	0.008	NR1I3, SMARCA4, CTCF, SMARCB1, GATAD2B, KAT6A, SOX11, CTNNB1, MEF2C, KMT2C
enzyme binding (GO:0019899)	-	2.27	0.042	NR1I3, SYNGAP1, ARID1A, CTCF, DYNC1H1, EPB41L1, GRIN2B, COL4A3BP, PPP2R5D, CACNG2, PACS1, CTNNB1, GRIN1, PPP2R1A, DYRK1A, MEF2C, EEF1A2, KMT2C, SMARCB1, SMARCA4
enhancer sequence-specific DNA binding (GO:0001158)	-	5.36	0.018	SMARCA4, KMT2C, SOX11, MEF2C, CTNNB1
nucleic acid binding transcription factor activity (GO:0001071)	-	2.65	0.005	ZMYND11, KANSL1, SMARCA4, CTCF, SMARCB1, NR1I3, ZBTB18, SMARCE1, KAT6A, SOX11, GATAD2B, GRIN1, MYT1L, PPP2R1A, PURA, KMT2C, CTNNB1, MEF2C
nucleic acid binding (GO:0003676)	-	1.44	0.002	CTCF, AHDC1, ARID1A, KMT2C, SMARCE1, ADNP, EEF1A2, CHAMP1, POGZ, ZMYND11, KAT6A, SOX11, CTNNB1, MBD5, DYNC1H1, DEAF1, NR1I3, ZBTB18, MYT1L, SETBP1, PURA, SMARCA4, MEF2C, ARID1B
DNA binding (GO:0003677)	-	1.92	0.0	GATAD2B, PPP2R5D, EHMT1, POGZ, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, EEF1A2, SETD5, ZMYND11, KAT6A, SOX11, CTNNB1, DEAF1, KANSL1, SMARCA4, MBD5, SMARCB1, MYT1L, ZBTB18, PPP2R1A, SETBP1, NR1I3, AHDC1, PURA, DYRK1A, MEF2C, ARID1B
Tat protein binding (GO:0030957)	-	7.66	0.0	SMARCB1, SMARCA4, CTNNB1
sequence-specific DNA binding (GO:0043565)	-	2.79	0.0	DYRK1A, NR1I3, GATAD2B, PPP2R5D, CTCF, SMARCB1, ZBTB18, SMARCE1, KAT6A, SOX11, SETD5, CTNNB1, PPP2R1A, PURA, KMT2C, MEF2C, SMARCA4
RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription (GO:0001190)	-	5.77	0.023	MEF2C, SOX11, SMARCA4, CTNNB1
transcription coactivator activity (GO:0003713)	-	4.04	0.0	NR1I3, SMARCA4, SMARCB1, SMARCE1, KAT6A, SOX11, CTNNB1, PPP2R1A, ARID1A, MEF2C, ARID1B
transcription cofactor activity (GO:0003712)	-	3.44	0.0	ZMYND11, NR1I3, SMARCA4, PPP2R5D, CTCF, MEF2C, SMARCB1, KAT6A, SMARCE1, EHMT1, SOX11, CTNNB1, PPP2R1A, ARID1A, GRIN2B, ARID1B
transcription factor binding transcription factor activity (GO:0000989)	-	3.36	0.0	ZMYND11, NR1I3, SMARCA4, PPP2R5D, CTCF, MEF2C, SMARCB1, KAT6A, SMARCE1, EHMT1, SOX11, CTNNB1, PPP2R1A, ARID1A, GRIN2B, ARID1B
protein binding transcription factor activity (GO:0000988)	-	3.35	0.0	SMARCE1, NR1I3, SMARCA4, PPP2R5D, CTCF, MEF2C, SMARCB1, KAT6A, ZMYND11, EHMT1, SOX11, CTNNB1, PPP2R1A, GRIN2B, ARID1A, ARID1B
sequence-specific DNA binding RNA polymerase II transcription factor activity (GO:0000981)	-	3.29	0.003	NR1I3, SMARCA4, CTCF, SMARCB1, PURA, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, MEF2C, KMT2C
protein homodimerization activity (GO:0042803)	NEW	3.16	0.033	ZMYND11, NR1I3, GRIN1, PPP2R5D, MEF2C, EEF1A2, SMARCB1, POGZ, SMARCE1, PACS1, CTNNB1, PPP2R1A, GRIN2B, EPB41L1, SMARCA4
regulatory region nucleic acid binding (GO:0001067)	-	3.03	0.001	NR1I3, DYRK1A, CTCF, MEF2C, SMARCB1, ZBTB18, GATAD2B, SMARCE1, KAT6A, SOX11, PURA, CTNNB1, KMT2C, SMARCA4
ionotropic glutamate receptor binding (GO:0035255)	-	6.56	0.001	GRIN1, GRIN2B, CACNG2, CTNNB1
glutamate receptor binding (GO:0035254)	-	6.13	0.01	GRIN2B, CACNG2, EPB41L1, GRIN1, CTNNB1
RNA polymerase II transcription coactivator activity (GO:0001105)	-	6.15	0.003	MEF2C, SOX11, SMARCA4, CTNNB1
phosphatase binding (GO:0019902)	NEW	4.63	0.009	GRIN1, DYNC1H1, CACNG2, SMARCA4, PPP2R1A, GRIN2B, CTNNB1
enhancer binding (GO:0035326)	-	5.21	0.048	SMARCA4, KMT2C, SOX11, MEF2C, CTNNB1
ligand-dependent nuclear receptor binding (GO:0016922)	-	6.6	0.029	SMARCE1, ARID1A, SMARCA4
transcription regulatory region DNA binding (GO:0044212)	-	3.03	0.001	NR1I3, DYRK1A, CTCF, MEF2C, SMARCB1, ZBTB18, SMARCE1, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, SMARCA4
protein heterodimerization activity (GO:0046982)	-	3.64	0.033	NR1I3, GRIN1, PPP2R5D, MEF2C, EPB41L1, GATAD2B, SMARCE1, CTNNB1, PPP2R1A, GRIN2B, SMARCB1, SMARCA4
sequence-specific DNA binding transcription factor activity (GO:0003700)	-	2.65	0.005	SMARCE1, KANSL1, NR1I3, SMARCA4, CTCF, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, GRIN1, PPP2R1A, PURA, KMT2C, MEF2C
transcription regulatory region sequence-specific DNA binding (GO:0000976)	-	3.24	0.023	NR1I3, SMARCA4, CTCF, SMARCB1, GATAD2B, KAT6A, SOX11, CTNNB1, KMT2C, MEF2C
RNA polymerase II regulatory region sequence-specific DNA binding (GO:0000977)	-	3.37	0.007	NR1I3, SMARCA4, CTCF, SMARCB1, GATAD2B, KAT6A, SOX11, CTNNB1, MEF2C, KMT2C
regulatory region DNA binding (GO:0000975)	-	3.03	0.001	NR1I3, DYRK1A, CTCF, SMARCB1, ZBTB18, GATAD2B, SMARCE1, KAT6A, SOX11, PURA, CTNNB1, MEF2C, KMT2C, SMARCA4
protein dimerization activity (GO:0046983)	-	2.72	0.024	ZMYND11, KANSL1, GRIN1, PPP2R5D, EPB41L1, SMARCB1, NR1I3, GATAD2B, SMARCE1, SETD5, PACS1, POGZ, CTNNB1, PPP2R1A, MEF2C, EEF1A2, KMT2C, GRIN2B, SMARCA4
chromatin binding (GO:0003682)	-	3.64	0.001	ADNP, CTNNB1, MBD5, CTCF, SMARCB1, SETD5, SMARCE1, KAT6A, SMARCA4, DYRK1A, ARID1A, MEF2C

GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
cellular process (GO:0009987)	0.26	40	KIF1A, PPP2R5D, SMARCB1, CACNG2, PACS1, PURA, KIRREL3, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, EPB41L1, DPP6, KANSL1, GRIN1, MBD5, DYNC1H1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, EHMT1, GATAD2B, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
biological regulation (GO:0065007)	0.39	35	PPP2R5D, SMARCB1, CACNG2, PACS1, GATAD2B, ARID1A, AUTS2, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, EPB41L1, DPP6, CDH15, MBD5, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, EHMT1, PURA, GRIN1, DYRK1A, MEF2C, COL4A3BP, ARID1B
regulation of biological process (GO:0050789)	0.45	35	PPP2R5D, EHMT1, PACS1, GATAD2B, ARID1A, AUTS2, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, CDH15, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, COL4A3BP, MBD5, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, CACNG2, PURA, EPB41L1, GRIN1, DYRK1A, MEF2C, ARID1B
regulation of cellular process (GO:0050794)	0.5	35	PPP2R5D, EHMT1, PACS1, GATAD2B, GRIN1, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, AUTS2, GRIN2B, SMARCB1, DPP6, CTNNB1, MBD5, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, CACNG2, PURA, EPB41L1, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
single-organism process (GO:0044699)	0.48	33	KIF1A, CTCF, EHMT1, PACS1, KIRREL3, GRIN1, ARID1A, AUTS2, SMARCE1, ADNP, SYNGAP1, POGZ, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, COL4A3BP, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SMARCA4, NR1I3, CACNG2, PURA, EPB41L1, CDH15, MEF2C
single-organism cellular process (GO:0044763)	0.65	30	KIF1A, CTCF, CACNG2, PACS1, KIRREL3, ARID1A, SMARCE1, ADNP, SYNGAP1, POGZ, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, GRIN1, MBD5, DYNC1H1, DEAF1, MYT1L, PPP2R1A, SMARCA4, NR1I3, PURA, EPB41L1, CDH15, MEF2C, COL4A3BP
organic substance metabolic process (GO:0071704)	0.63	29	PPP2R5D, EHMT1, GATAD2B, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, SMARCA4, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, PURA, DYRK1A, MEF2C, COL4A3BP, ARID1B
primary metabolic process (GO:0044238)	0.69	29	PPP2R5D, EHMT1, PURA, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, SMARCA4, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, NR1I3, GATAD2B, DYRK1A, MEF2C, COL4A3BP, ARID1B
metabolic process (GO:0008152)	0.58	29	PPP2R5D, EHMT1, GATAD2B, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, COL4A3BP, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, PURA, DYRK1A, MEF2C, ARID1B
macromolecule metabolic process (GO:0043170)	0.83	29	PPP2R5D, EHMT1, GATAD2B, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, GRIN1, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, PURA, COL4A3BP, DYRK1A, MEF2C, ARID1B
cellular macromolecule metabolic process (GO:0044260)	0.93	28	PPP2R5D, EHMT1, PURA, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, KANSL1, COL4A3BP, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, DYRK1A, MEF2C, ARID1B
cellular component organization or biogenesis (GO:0071840)	1.22	28	CTCF, EHMT1, PACS1, GATAD2B, KIRREL3, GRIN1, ARID1A, SMARCE1, SYNGAP1, POGZ, ZMYND11, KAT6A, CTNNB1, EPB41L1, DPP6, KANSL1, COL4A3BP, MBD5, DYNC1H1, SMARCB1, PPP2R1A, KMT2C, SMARCA4, CACNG2, PURA, CDH15, MEF2C, ARID1B
cellular metabolic process (GO:0044237)	0.69	28	PPP2R5D, EHMT1, GATAD2B, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, KANSL1, COL4A3BP, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, PURA, DYRK1A, MEF2C, ARID1B
cellular component organization (GO:0016043)	1.24	28	CTCF, CACNG2, PACS1, GATAD2B, KIRREL3, GRIN1, ARID1A, SMARCE1, SYNGAP1, POGZ, ZMYND11, KAT6A, CTNNB1, SMARCB1, DPP6, KANSL1, COL4A3BP, MBD5, DYNC1H1, EPB41L1, PPP2R1A, KMT2C, SMARCA4, EHMT1, PURA, CDH15, MEF2C, ARID1B
regulation of cellular metabolic process (GO:0031323)	1.07	27	PPP2R5D, EHMT1, GATAD2B, GRIN1, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, PURA, DYRK1A, MEF2C, ARID1B
regulation of primary metabolic process (GO:0080090)	1.08	27	PPP2R5D, EHMT1, PURA, GRIN1, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, DYRK1A, MEF2C, ARID1B
regulation of metabolic process (GO:0019222)	1.02	27	PPP2R5D, EHMT1, PURA, GRIN1, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, DYRK1A, MEF2C, ARID1B
regulation of macromolecule metabolic process (GO:0060255)	1.08	26	PPP2R5D, EHMT1, GATAD2B, GRIN1, ARID1A, SMARCE1, ADNP, CTCF, SYNGAP1, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, PURA, DYRK1A, MEF2C, ARID1B
regulation of nucleobase-containing compound metabolic process (GO:0019219)	1.43	24	CTCF, EHMT1, PURA, GRIN1, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, DYRK1A, MEF2C, ARID1B
regulation of RNA metabolic process (GO:0051252)	1.52	24	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, DYRK1A, MEF2C, ARID1B
regulation of nitrogen compound metabolic process (GO:0051171)	1.36	24	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, DYRK1A, MEF2C, ARID1B
regulation of gene expression (GO:0010468)	1.37	24	CTCF, EHMT1, PURA, GRIN1, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, DYRK1A, MEF2C, ARID1B
regulation of cellular macromolecule biosynthetic process (GO:2000112)	1.46	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of RNA biosynthetic process (GO:2001141)	1.55	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of biosynthetic process (GO:0009889)	1.37	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of nucleic acid-templated transcription (GO:1903506)	1.55	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of transcription, DNA-templated (GO:0006355)	1.56	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of macromolecule biosynthetic process (GO:0010556)	1.43	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
regulation of cellular biosynthetic process (GO:0031326)	1.38	23	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, AUTS2, SMARCB1, CTNNB1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, GATAD2B, GRIN1, MEF2C, ARID1B
cellular nitrogen compound metabolic process (GO:0034641)	1.22	22	CTCF, EHMT1, PURA, ARID1A, ADNP, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, COL4A3BP, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
nitrogen compound metabolic process (GO:0006807)	1.13	22	CTCF, EHMT1, PURA, ARID1A, ADNP, EEF1A2, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, COL4A3BP, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
positive regulation of biological process (GO:0048518)	1.2	21	ADNP, AUTS2, MBD5, CTCF, SMARCA4, EEF1A2, SMARCB1, NR1I3, PURA, KAT6A, SOX11, DPP6, CDH15, GRIN1, PPP2R1A, DYRK1A, MEF2C, CTNNB1, DEAF1, ARID1B, ARID1A
negative regulation of biological process (GO:0048519)	1.33	21	ZMYND11, ADNP, DYRK1A, SYNGAP1, KAT6A, DEAF1, SMARCB1, NR1I3, GATAD2B, SMARCE1, EHMT1, CTCF, SOX11, ZBTB18, CTNNB1, GRIN1, PPP2R1A, PURA, MEF2C, ARID1A, SMARCA4
anatomical structure development (GO:0048856)	1.58	21	MYT1L, MBD5, CTNNB1, SYNGAP1, DEAF1, SMARCA4, SMARCB1, KAT6A, ZBTB18, COL4A3BP, SMARCE1, PPP2R5D, EHMT1, SOX11, PURA, DYRK1A, KIRREL3, GRIN1, MEF2C, ARID1A, ARID1B
developmental process (GO:0032502)	1.36	21	MYT1L, MBD5, COL4A3BP, SYNGAP1, DEAF1, SMARCA4, SMARCB1, KAT6A, ZBTB18, SMARCE1, PPP2R5D, EHMT1, SOX11, PURA, DYRK1A, KIRREL3, GRIN1, MEF2C, CTNNB1, ARID1A, ARID1B
negative regulation of cellular process (GO:0048523)	1.41	21	SMARCE1, ADNP, DYRK1A, SYNGAP1, KAT6A, DEAF1, SMARCB1, NR1I3, ZBTB18, ZMYND11, EHMT1, CTCF, SOX11, GATAD2B, CTNNB1, GRIN1, PPP2R1A, PURA, MEF2C, ARID1A, SMARCA4
nucleobase-containing compound metabolic process (GO:0006139)	1.35	20	NR1I3, GATAD2B, CTCF, KAT6A, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, EHMT1, SOX11, PURA, CTNNB1, MYT1L, PPP2R1A, SMARCA4, ARID1A, KMT2C, DEAF1, ARID1B
organic substance biosynthetic process (GO:1901576)	1.34	20	NR1I3, COL4A3BP, ARID1A, CTCF, DEAF1, SMARCA4, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, MYT1L, PURA, MEF2C, EEF1A2, KMT2C, ARID1B
cellular aromatic compound metabolic process (GO:0006725)	1.3	20	ADNP, NR1I3, SMARCA4, CTCF, KAT6A, MEF2C, DEAF1, SMARCB1, MYT1L, ZBTB18, ZMYND11, EHMT1, SOX11, GATAD2B, CTNNB1, PPP2R1A, PURA, KMT2C, ARID1A, ARID1B
nucleic acid metabolic process (GO:0090304)	1.46	20	NR1I3, GATAD2B, CTCF, KAT6A, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, EHMT1, SOX11, PURA, CTNNB1, MYT1L, PPP2R1A, SMARCA4, KMT2C, ARID1A, ARID1B
cellular biosynthetic process (GO:0044249)	1.37	20	NR1I3, CTNNB1, ARID1A, CTCF, MEF2C, EEF1A2, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SMARCA4, SOX11, GATAD2B, COL4A3BP, MYT1L, PURA, KMT2C, DEAF1, ARID1B
biosynthetic process (GO:0009058)	1.32	20	NR1I3, COL4A3BP, ARID1A, CTCF, DEAF1, SMARCA4, SMARCB1, ADNP, ZBTB18, ZMYND11, MEF2C, KAT6A, SOX11, GATAD2B, CTNNB1, MYT1L, PURA, KMT2C, EEF1A2, ARID1B
heterocycle metabolic process (GO:0046483)	1.31	20	ADNP, NR1I3, SMARCA4, CTCF, KAT6A, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, EHMT1, SOX11, GATAD2B, CTNNB1, PPP2R1A, PURA, ARID1A, KMT2C, DEAF1, ARID1B
organic cyclic compound metabolic process (GO:1901360)	1.26	20	ADNP, NR1I3, CTNNB1, CTCF, KAT6A, DEAF1, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, EHMT1, SOX11, GATAD2B, SMARCA4, PPP2R1A, PURA, KMT2C, ARID1A, ARID1B
positive regulation of cellular process (GO:0048522)	1.3	20	ADNP, MEF2C, CTCF, MBD5, SMARCA4, SMARCB1, NR1I3, PURA, CTNNB1, CDH15, KAT6A, SOX11, AUTS2, GRIN1, PPP2R1A, DYRK1A, ARID1A, EEF1A2, DEAF1, ARID1B
RNA metabolic process (GO:0016070)	1.59	19	ADNP, NR1I3, SMARCA4, ARID1A, CTCF, DEAF1, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PPP2R1A, PURA, KMT2C, MEF2C, ARID1B
negative regulation of metabolic process (GO:0009892)	1.93	19	ZMYND11, ADNP, GATAD2B, CTCF, KAT6A, DEAF1, SMARCB1, NR1I3, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, DYRK1A, PPP2R1A, MEF2C, CTNNB1, ARID1A, SMARCA4
cellular nitrogen compound biosynthetic process (GO:0044271)	1.59	19	ADNP, NR1I3, SMARCA4, CTCF, MEF2C, DEAF1, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, EEF1A2, ARID1A, ARID1B
macromolecule biosynthetic process (GO:0009059)	1.61	19	MYT1L, GATAD2B, ARID1A, CTCF, DEAF1, MEF2C, EEF1A2, NR1I3, ZBTB18, ADNP, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, SMARCA4, KMT2C, SMARCB1, ARID1B
cellular macromolecule biosynthetic process (GO:0034645)	1.66	19	NR1I3, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, EEF1A2, ARID1A, ARID1B
negative regulation of macromolecule metabolic process (GO:0010605)	2.01	19	ZMYND11, ADNP, DYRK1A, CTCF, KAT6A, MEF2C, SMARCB1, NR1I3, ZBTB18, GATAD2B, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, PPP2R1A, ARID1A, DEAF1, SMARCA4
RNA biosynthetic process (GO:0032774)	1.84	18	NR1I3, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, ARID1A, ARID1B
negative regulation of cellular metabolic process (GO:0031324)	2.01	18	ZMYND11, NR1I3, SMARCA4, CTCF, MEF2C, SMARCB1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, GATAD2B, DYRK1A, PPP2R1A, PURA, ARID1A, CTNNB1, DEAF1
transcription, DNA-templated (GO:0006351)	1.91	18	NR1I3, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, ARID1A, ARID1B
nucleobase-containing compound biosynthetic process (GO:0034654)	1.72	18	NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, MYT1L, PURA, KMT2C, ARID1A, ARID1B
aromatic compound biosynthetic process (GO:0019438)	1.7	18	ADNP, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, NR1I3, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, ARID1A, ARID1B
organic cyclic compound biosynthetic process (GO:1901362)	1.66	18	NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, MYT1L, PURA, KMT2C, ARID1A, ARID1B
nucleic acid-templated transcription (GO:0097659)	1.91	18	ADNP, GATAD2B, ARID1A, CTCF, DEAF1, SMARCB1, NR1I3, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, SMARCA4, MYT1L, KMT2C, CTNNB1, MEF2C, ARID1B
heterocycle biosynthetic process (GO:0018130)	1.7	18	NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, ADNP, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, MYT1L, PURA, KMT2C, ARID1A, ARID1B
macromolecular complex subunit organization (GO:0043933)	2.14	17	SMARCE1, KANSL1, GRIN1, CTCF, DYNC1H1, SMARCB1, KAT6A, POGZ, ZMYND11, EHMT1, GATAD2B, CTNNB1, PPP2R1A, SMARCA4, ARID1A, KMT2C, ARID1B
negative regulation of gene expression (GO:0010629)	2.48	17	ZMYND11, ADNP, GATAD2B, CTCF, KAT6A, DEAF1, NR1I3, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, DYRK1A, MEF2C, CTNNB1, ARID1A, SMARCA4
regulation of transcription from RNA polymerase II promoter (GO:0006357)	2.24	17	ZMYND11, NR1I3, GATAD2B, CTCF, MEF2C, SMARCB1, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, GRIN1, ARID1A, DEAF1, SMARCA4, AUTS2
negative regulation of nucleobase-containing compound metabolic process (GO:0045934)	2.55	16	ZMYND11, NR1I3, DYRK1A, CTCF, MEF2C, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, GATAD2B, CTNNB1, PURA, ARID1A, SMARCA4
protein metabolic process (GO:0019538)	1.45	16	KANSL1, PPP2R5D, SYNGAP1, EEF1A2, KAT6A, COL4A3BP, EHMT1, SOX11, CTNNB1, GRIN1, PPP2R1A, DYRK1A, GRIN2B, KMT2C, MEF2C, DPP6
negative regulation of RNA metabolic process (GO:0051253)	2.66	16	ZMYND11, NR1I3, DYRK1A, CTCF, MEF2C, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, GATAD2B, CTNNB1, PURA, ARID1A, SMARCA4
negative regulation of nitrogen compound metabolic process (GO:0051172)	2.47	16	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, DYRK1A, MEF2C, CTNNB1, ARID1A, SMARCA4
positive regulation of cellular metabolic process (GO:0031325)	1.81	16	NR1I3, CTNNB1, ARID1A, CTCF, SMARCA4, EEF1A2, SMARCB1, ADNP, KAT6A, SOX11, AUTS2, GRIN1, DYRK1A, MEF2C, DEAF1, ARID1B
positive regulation of metabolic process (GO:0009893)	1.74	16	NR1I3, DYRK1A, CTCF, MEF2C, DEAF1, ADNP, KAT6A, SMARCA4, SOX11, CTNNB1, GRIN1, ARID1A, EEF1A2, SMARCB1, ARID1B, AUTS2
single-organism developmental process (GO:0044767)	1.49	15	MYT1L, COL4A3BP, SYNGAP1, DEAF1, SMARCB1, KAT6A, ZBTB18, EHMT1, SOX11, CTNNB1, KIRREL3, GRIN1, ARID1A, MEF2C, SMARCA4
positive regulation of macromolecule metabolic process (GO:0010604)	1.81	15	NR1I3, DYRK1A, CTCF, MEF2C, DEAF1, ADNP, KAT6A, SMARCA4, SOX11, CTNNB1, GRIN1, ARID1A, SMARCB1, ARID1B, AUTS2
negative regulation of biosynthetic process (GO:0009890)	2.47	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C, SMARCA4
negative regulation of cellular biosynthetic process (GO:0031327)	2.49	15	ZMYND11, NR1I3, GATAD2B, CTCF, MEF2C, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, SMARCA4
regulation of response to stimulus (GO:0048583)	1.54	15	DYRK1A, MBD5, SYNGAP1, SMARCB1, CACNG2, KAT6A, ZMYND11, EHMT1, SOX11, CTNNB1, GRIN1, PPP2R1A, PACS1, MEF2C, SMARCA4
negative regulation of cellular macromolecule biosynthetic process (GO:2000113)	2.6	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, SMARCA4, ARID1A, CTNNB1, MEF2C
negative regulation of nucleic acid-templated transcription (GO:1903507)	2.71	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C, SMARCA4
negative regulation of RNA biosynthetic process (GO:1902679)	2.7	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, MEF2C, ARID1A, SMARCA4
negative regulation of transcription, DNA-templated (GO:0045892)	2.75	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C, SMARCA4
regulation of signaling (GO:0023051)	1.72	15	ADNP, MBD5, SYNGAP1, KAT6A, SMARCB1, CACNG2, ZMYND11, EHMT1, SOX11, CTNNB1, GRIN1, PPP2R1A, DYRK1A, MEF2C, SMARCA4
regulation of molecular function (GO:0065009)	1.78	15	ADNP, PPP2R5D, SYNGAP1, CTCF, SMARCB1, GRIN2B, PACS1, CACNG2, SOX11, CTNNB1, PPP2R1A, GRIN1, MEF2C, EEF1A2, SMARCA4
regulation of cell communication (GO:0010646)	1.73	15	ADNP, MBD5, SYNGAP1, SMARCB1, CACNG2, KAT6A, ZMYND11, EHMT1, SOX11, CTNNB1, GRIN1, PPP2R1A, DYRK1A, MEF2C, SMARCA4
negative regulation of macromolecule biosynthetic process (GO:0010558)	2.53	15	ZMYND11, NR1I3, GATAD2B, CTCF, DEAF1, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C, SMARCA4
cellular protein metabolic process (GO:0044267)	1.63	14	KANSL1, PPP2R5D, SYNGAP1, EEF1A2, KAT6A, COL4A3BP, EHMT1, SOX11, DYRK1A, PPP2R1A, GRIN1, GRIN2B, KMT2C, MEF2C
multicellular organismal process (GO:0032501)	1.45	14	MYT1L, CTNNB1, SYNGAP1, DEAF1, SMARCB1, CACNG2, ZBTB18, ADNP, EHMT1, SOX11, COL4A3BP, GRIN1, GRIN2B, MEF2C
positive regulation of nucleobase-containing compound metabolic process (GO:0045935)	2.35	14	NR1I3, CTNNB1, CTCF, SMARCA4, DEAF1, SMARCB1, ADNP, KAT6A, SOX11, AUTS2, GRIN1, ARID1A, MEF2C, ARID1B
nervous system development (GO:0007399)	3.53	14	MYT1L, PPP2R5D, MBD5, SMARCA4, DEAF1, PURA, SMARCE1, MEF2C, SOX11, CTNNB1, DYRK1A, ARID1A, SMARCB1, ARID1B
single-multicellular organism process (GO:0044707)	1.78	14	ADNP, CTNNB1, SYNGAP1, DEAF1, CACNG2, GRIN2B, MYT1L, ZBTB18, EHMT1, SOX11, COL4A3BP, GRIN1, MEF2C, SMARCB1
positive regulation of cellular biosynthetic process (GO:0031328)	2.3	14	ADNP, CTNNB1, CTCF, DEAF1, SMARCB1, NR1I3, KAT6A, SOX11, AUTS2, GRIN1, SMARCA4, ARID1A, MEF2C, ARID1B
regulation of signal transduction (GO:0009966)	1.84	14	MBD5, SYNGAP1, SMARCB1, CACNG2, KAT6A, ZMYND11, EHMT1, SOX11, CTNNB1, GRIN1, PPP2R1A, DYRK1A, MEF2C, SMARCA4
cellular developmental process (GO:0048869)	1.82	14	NR1I3, COL4A3BP, MEF2C, DEAF1, MYT1L, PURA, SMARCE1, KAT6A, SOX11, CTNNB1, KIRREL3, ARID1A, SMARCB1, SMARCA4
response to stimulus (GO:0050896)	1.22	14	ADNP, CTNNB1, SYNGAP1, MEF2C, EEF1A2, SMARCB1, KAT6A, EHMT1, COL4A3BP, PPP2R1A, GRIN1, GRIN2B, DEAF1, AUTS2
positive regulation of biosynthetic process (GO:0009891)	2.29	14	ADNP, CTNNB1, CTCF, DEAF1, SMARCB1, NR1I3, KAT6A, SOX11, AUTS2, GRIN1, SMARCA4, MEF2C, ARID1A, ARID1B
macromolecule modification (GO:0043412)	1.73	14	KANSL1, DYRK1A, SYNGAP1, CTCF, KAT6A, GATAD2B, PPP2R5D, EHMT1, COL4A3BP, PPP2R1A, GRIN1, MEF2C, KMT2C, GRIN2B
positive regulation of nitrogen compound metabolic process (GO:0051173)	2.29	14	NR1I3, AUTS2, CTCF, DEAF1, SMARCA4, SMARCB1, ADNP, KAT6A, SOX11, CTNNB1, GRIN1, ARID1A, MEF2C, ARID1B
system development (GO:0048731)	2.92	14	MYT1L, DYRK1A, MBD5, MEF2C, DEAF1, PURA, SMARCE1, PPP2R5D, SOX11, CTNNB1, SMARCA4, ARID1A, SMARCB1, ARID1B
positive regulation of nucleic acid-templated transcription (GO:1903508)	2.56	13	NR1I3, AUTS2, ARID1A, CTCF, DEAF1, KAT6A, SOX11, CTNNB1, GRIN1, SMARCA4, MEF2C, SMARCB1, ARID1B
chromatin organization (GO:0006325)	3.28	13	ZMYND11, KANSL1, SMARCA4, CTCF, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, CTNNB1, ARID1A, KMT2C, ARID1B
positive regulation of RNA metabolic process (GO:0051254)	2.51	13	NR1I3, AUTS2, ARID1A, CTCF, SMARCA4, DEAF1, KAT6A, SOX11, CTNNB1, GRIN1, MEF2C, SMARCB1, ARID1B
positive regulation of RNA biosynthetic process (GO:1902680)	2.54	13	NR1I3, AUTS2, ARID1A, CTCF, DEAF1, KAT6A, SOX11, CTNNB1, GRIN1, SMARCA4, MEF2C, SMARCB1, ARID1B
positive regulation of macromolecule biosynthetic process (GO:0010557)	2.39	13	NR1I3, CTNNB1, CTCF, SMARCA4, DEAF1, SMARCB1, KAT6A, SOX11, AUTS2, GRIN1, MEF2C, ARID1A, ARID1B
positive regulation of gene expression (GO:0010628)	2.35	13	NR1I3, CTNNB1, CTCF, SMARCA4, DEAF1, SMARCB1, KAT6A, SOX11, AUTS2, GRIN1, MEF2C, ARID1A, ARID1B
positive regulation of transcription, DNA-templated (GO:0045893)	2.56	13	NR1I3, AUTS2, ARID1A, CTCF, DEAF1, KAT6A, SOX11, CTNNB1, GRIN1, SMARCA4, MEF2C, SMARCB1, ARID1B
localization (GO:0051179)	1.4	13	KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, EPB41L1, CACNG2, CHAMP1, PACS1, CTNNB1, GRIN1, GRIN2B, ARID1A, DPP6
protein modification process (GO:0036211)	1.79	12	KANSL1, PPP2R5D, SYNGAP1, KAT6A, COL4A3BP, EHMT1, DYRK1A, PPP2R1A, GRIN1, MEF2C, KMT2C, GRIN2B
regulation of biological quality (GO:0065008)	1.68	12	ADNP, MBD5, SYNGAP1, EPB41L1, COL4A3BP, CACNG2, SOX11, CTNNB1, GRIN1, MEF2C, SMARCB1, SMARCA4
cellular protein modification process (GO:0006464)	1.79	12	KANSL1, PPP2R5D, SYNGAP1, GRIN2B, KAT6A, EHMT1, COL4A3BP, GRIN1, PPP2R1A, DYRK1A, MEF2C, KMT2C
regulation of cellular protein metabolic process (GO:0032268)	1.99	11	ADNP, CTNNB1, SYNGAP1, CTCF, SMARCB1, PURA, ZMYND11, PPP2R5D, DYRK1A, PPP2R1A, AUTS2
regulation of protein metabolic process (GO:0051246)	1.93	11	ADNP, CTNNB1, SYNGAP1, CTCF, SMARCB1, PURA, ZMYND11, PPP2R5D, DYRK1A, PPP2R1A, AUTS2
signal transduction (GO:0007165)	1.28	11	NR1I3, CTNNB1, SYNGAP1, MEF2C, PPP2R5D, SOX11, COL4A3BP, PPP2R1A, GRIN1, GRIN2B, ARID1A
chromatin modification (GO:0016568)	4.06	11	ZMYND11, KANSL1, CTCF, SMARCB1, KAT6A, SMARCE1, EHMT1, SMARCA4, KMT2C, ARID1A, ARID1B
regulation of cellular component organization (GO:0051128)	2.01	11	ADNP, AUTS2, SYNGAP1, CTCF, EPB41L1, CTNNB1, PPP2R1A, GRIN1, MEF2C, SMARCB1, SMARCA4
regulation of multicellular organismal process (GO:0051239)	1.87	10	ADNP, MBD5, SYNGAP1, DEAF1, CACNG2, SOX11, CTNNB1, PPP2R1A, GRIN1, MEF2C
protein complex subunit organization (GO:0071822)	2.6	10	GRIN1, CTCF, SMARCB1, POGZ, SMARCE1, KAT6A, CTNNB1, PPP2R1A, ARID1A, SMARCA4
negative regulation of transcription from RNA polymerase II promoter (GO:0000122)	3.12	10	SMARCA4, CTCF, ZBTB18, ZMYND11, EHMT1, SOX11, GATAD2B, CTNNB1, MEF2C, ARID1A
regulation of developmental process (GO:0050793)	2.1	10	ADNP, SYNGAP1, MBD5, DEAF1, SOX11, CDH15, PPP2R1A, GRIN1, MEF2C, CTNNB1
cell differentiation (GO:0030154)	2.14	10	NR1I3, SMARCB1, MYT1L, PURA, SMARCE1, KAT6A, SOX11, CTNNB1, ARID1A, MEF2C
positive regulation of molecular function (GO:0044093)	2.23	10	ADNP, GRIN1, SYNGAP1, EEF1A2, SMARCB1, PACS1, CTNNB1, MEF2C, GRIN2B, SMARCA4
regulation of protein modification process (GO:0031399)	2.32	10	ADNP, CTNNB1, SYNGAP1, CTCF, SMARCB1, ZMYND11, PPP2R5D, DYRK1A, PPP2R1A, AUTS2
organelle organization (GO:0006996)	2.02	9	MBD5, DYNC1H1, EPB41L1, PURA, KAT6A, POGZ, COL4A3BP, PPP2R1A, ARID1A
regulation of catalytic activity (GO:0050790)	1.97	9	ADNP, SYNGAP1, PPP2R5D, EEF1A2, CTNNB1, PPP2R1A, GRIN1, GRIN2B, MEF2C
establishment of localization (GO:0051234)	1.48	9	KIF1A, CTNNB1, DYNC1H1, COL4A3BP, CACNG2, PACS1, GRIN1, GRIN2B, ARID1A
transport (GO:0006810)	1.51	9	KIF1A, CTNNB1, DYNC1H1, CACNG2, PACS1, COL4A3BP, GRIN1, ARID1A, GRIN2B
behavior (GO:0007610)	3.47	9	ADNP, SYNGAP1, MBD5, DEAF1, AUTS2, KIRREL3, GRIN1, MEF2C, GRIN2B
cellular component assembly (GO:0022607)	2.14	9	GRIN1, CTCF, DYNC1H1, POGZ, KIRREL3, KAT6A, CTNNB1, PPP2R1A, SMARCA4
positive regulation of transcription from RNA polymerase II promoter (GO:0045944)	2.81	9	NR1I3, CTNNB1, CTCF, SMARCB1, SOX11, GRIN1, MEF2C, SMARCA4, AUTS2
regulation of cell death (GO:0010941)	2.43	9	ADNP, GRIN1, SYNGAP1, EEF1A2, ZMYND11, SOX11, CTNNB1, PPP2R1A, MEF2C
regulation of phosphorus metabolic process (GO:0051174)	2.35	8	ADNP, PPP2R5D, SYNGAP1, EEF1A2, ZMYND11, CTNNB1, PPP2R1A, MEF2C
regulation of phosphate metabolic process (GO:0019220)	2.35	8	ADNP, PPP2R5D, SYNGAP1, EEF1A2, ZMYND11, CTNNB1, PPP2R1A, MEF2C
single-organism behavior (GO:0044708)	3.79	8	ADNP, SYNGAP1, MBD5, DEAF1, AUTS2, GRIN1, MEF2C, GRIN2B
positive regulation of response to stimulus (GO:0048584)	2.18	8	CTNNB1, MBD5, SMARCB1, SOX11, GRIN1, PPP2R1A, MEF2C, SMARCA4
regulation of programmed cell death (GO:0043067)	2.49	8	ADNP, GRIN1, SYNGAP1, EEF1A2, ZMYND11, CTNNB1, PPP2R1A, MEF2C
macromolecular complex assembly (GO:0065003)	2.55	8	CTNNB1, CTCF, DYNC1H1, POGZ, KAT6A, SMARCA4, PPP2R1A, GRIN1
phosphate-containing compound metabolic process (GO:0006796)	2.16	8	SYNGAP1, PPP2R5D, COL4A3BP, GRIN1, PPP2R1A, DYRK1A, GRIN2B, MEF2C
regulation of cell differentiation (GO:0045595)	2.42	8	ADNP, CTNNB1, SYNGAP1, SOX11, CDH15, PPP2R1A, GRIN1, MEF2C
cellular localization (GO:0051641)	2.32	8	KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, CHAMP1, PACS1, CTNNB1, DPP6
phosphorus metabolic process (GO:0006793)	2.15	8	SYNGAP1, PPP2R5D, COL4A3BP, GRIN1, PPP2R1A, DYRK1A, GRIN2B, MEF2C
response to chemical (GO:0042221)	1.98	8	ADNP, CTNNB1, EEF1A2, EHMT1, GRIN1, PPP2R1A, GRIN2B, MEF2C
regulation of intracellular signal transduction (GO:1902531)	2.31	8	DYRK1A, SYNGAP1, KAT6A, ZMYND11, EHMT1, SOX11, CTNNB1, PPP2R1A
regulation of apoptotic process (GO:0042981)	2.5	8	ADNP, GRIN1, SYNGAP1, EEF1A2, ZMYND11, CTNNB1, PPP2R1A, MEF2C
multicellular organism development (GO:0007275)	2.54	8	MYT1L, CTNNB1, DEAF1, ZBTB18, EHMT1, SOX11, COL4A3BP, MEF2C
single-organism localization (GO:1902578)	2.09	8	KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, EPB41L1, PACS1, CTNNB1, DPP6
system process (GO:0003008)	2.3	8	ADNP, GRIN1, SYNGAP1, DEAF1, CACNG2, COL4A3BP, MEF2C, GRIN2B
cellular response to stimulus (GO:0051716)	1.97	7	ADNP, COL4A3BP, SMARCB1, KAT6A, CTNNB1, GRIN1, MEF2C
chromatin remodeling (GO:0006338)	4.78	7	SMARCA4, SMARCB1, GATAD2B, SMARCE1, CTNNB1, ARID1A, ARID1B
negative regulation of signaling (GO:0023057)	2.65	7	ADNP, DYRK1A, SYNGAP1, ZMYND11, CTNNB1, PPP2R1A, SMARCA4
positive regulation of signal transduction (GO:0009967)	2.5	7	CTNNB1, MBD5, SMARCB1, SOX11, GRIN1, PPP2R1A, SMARCA4
negative regulation of response to stimulus (GO:0048585)	2.52	7	CTNNB1, SYNGAP1, ZMYND11, DYRK1A, PPP2R1A, GRIN1, SMARCA4
regulation of cell development (GO:0060284)	3.01	7	ADNP, CTNNB1, SYNGAP1, SOX11, GRIN1, PPP2R1A, MEF2C
positive regulation of signaling (GO:0023056)	2.41	7	CTNNB1, MBD5, SMARCB1, SOX11, GRIN1, PPP2R1A, SMARCA4
reproductive process (GO:0022414)	2.55	7	ADNP, CTNNB1, DEAF1, GRIN1, PPP2R1A, ARID1A, SMARCA4
regulation of multicellular organismal development (GO:2000026)	2.31	7	ADNP, GRIN1, SYNGAP1, DEAF1, SOX11, CTNNB1, MEF2C
negative regulation of cell communication (GO:0010648)	2.66	7	ADNP, DYRK1A, SYNGAP1, ZMYND11, CTNNB1, PPP2R1A, SMARCA4
negative regulation of cell death (GO:0060548)	2.95	7	ADNP, CTNNB1, SYNGAP1, ZMYND11, SOX11, GRIN1, MEF2C
neurological system process (GO:0050877)	2.64	7	ADNP, SYNGAP1, DEAF1, CACNG2, GRIN1, GRIN2B, MEF2C
positive regulation of cell communication (GO:0010647)	2.41	7	CTNNB1, MBD5, SMARCB1, SOX11, GRIN1, PPP2R1A, SMARCA4
single-organism cellular localization (GO:1902580)	3.16	7	KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, PACS1, CTNNB1, DPP6
positive regulation of catalytic activity (GO:0043085)	2.4	7	ADNP, CTNNB1, SYNGAP1, EEF1A2, GRIN1, GRIN2B, MEF2C
multi-organism process (GO:0051704)	2.65	7	GRIN1, SMARCB1, ZMYND11, PACS1, SMARCA4, KIRREL3, MEF2C
nucleosome organization (GO:0034728)	4.79	6	CTCF, SMARCB1, SMARCE1, KAT6A, SMARCA4, ARID1A
regulation of transport (GO:0051049)	2.24	6	CTNNB1, CACNG2, SOX11, GRIN1, MEF2C, DPP6
learning or memory (GO:0007611)	4.33	6	ADNP, SYNGAP1, DEAF1, GRIN1, GRIN2B, MEF2C
homeostatic process (GO:0042592)	2.61	6	ADNP, CTNNB1, MBD5, GRIN1, MEF2C, COL4A3BP
intracellular signal transduction (GO:0035556)	2.39	6	SYNGAP1, SOX11, GRIN1, PPP2R1A, MEF2C, GRIN2B
anatomical structure morphogenesis (GO:0009653)	2.53	6	CTNNB1, DEAF1, SOX11, COL4A3BP, KIRREL3, MEF2C
protein-DNA complex subunit organization (GO:0071824)	4.45	6	CTCF, SMARCB1, SMARCE1, KAT6A, SMARCA4, ARID1A
regulation of neurogenesis (GO:0050767)	3.21	6	ADNP, CTNNB1, SYNGAP1, SOX11, GRIN1, MEF2C
single-organism metabolic process (GO:0044710)	1.63	6	COL4A3BP, SYNGAP1, GRIN1, PPP2R1A, GRIN2B, MEF2C
negative regulation of signal transduction (GO:0009968)	2.75	6	SMARCA4, SYNGAP1, ZMYND11, DYRK1A, PPP2R1A, CTNNB1
regulation of growth (GO:0040008)	3.26	6	ADNP, MBD5, EPB41L1, SMARCA4, PPP2R1A, MEF2C
negative regulation of apoptotic process (GO:0043066)	3.04	6	ADNP, CTNNB1, SYNGAP1, ZMYND11, GRIN1, MEF2C
phosphorylation (GO:0016310)	2.63	6	COL4A3BP, SYNGAP1, DYRK1A, GRIN1, MEF2C, GRIN2B
negative regulation of programmed cell death (GO:0043069)	3.02	6	ADNP, CTNNB1, SYNGAP1, ZMYND11, GRIN1, MEF2C
regulation of cell proliferation (GO:0042127)	2.41	6	SMARCB1, PURA, SOX11, CTNNB1, MEF2C, DEAF1
regulation of hydrolase activity (GO:0051336)	2.53	6	SYNGAP1, PPP2R5D, GRIN1, PPP2R1A, GRIN2B, MEF2C
protein phosphorylation (GO:0006468)	2.89	6	COL4A3BP, SYNGAP1, DYRK1A, GRIN1, GRIN2B, MEF2C
protein complex assembly (GO:0006461)	2.78	6	SMARCA4, POGZ, KAT6A, GRIN1, PPP2R1A, CTNNB1
cellular component disassembly (GO:0022411)	3.52	6	CTNNB1, MBD5, SMARCB1, SMARCE1, SMARCA4, ARID1A
regulation of localization (GO:0032879)	1.94	6	CTNNB1, CACNG2, SOX11, GRIN1, MEF2C, DPP6
response to organic substance (GO:0010033)	2.2	6	ADNP, CTNNB1, GRIN1, PPP2R1A, MEF2C, GRIN2B
regulation of phosphorylation (GO:0042325)	2.5	6	ADNP, SYNGAP1, EEF1A2, ZMYND11, CTNNB1, PPP2R1A
single organism reproductive process (GO:0044702)	2.73	6	ADNP, CTNNB1, DEAF1, SMARCA4, PPP2R1A, ARID1A
cognition (GO:0050890)	4.2	6	ADNP, SYNGAP1, DEAF1, GRIN1, GRIN2B, MEF2C
regulation of nervous system development (GO:0051960)	3.1	6	ADNP, CTNNB1, SYNGAP1, SOX11, GRIN1, MEF2C
ATP-dependent chromatin remodeling (GO:0043044)	5.6	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, GATAD2B
regulation of binding (GO:0051098)	4.08	5	PACS1, MEF2C, SOX11, ADNP, CTNNB1
regulation of organelle organization (GO:0033043)	2.72	5	MEF2C, SMARCB1, AUTS2, CTNNB1, CTCF
protein localization (GO:0008104)	2.36	5	CHAMP1, PACS1, CTNNB1, SYNGAP1, DPP6
cell development (GO:0048468)	3.28	5	DEAF1, MEF2C, SOX11, SMARCA4, CTNNB1
movement of cell or subcellular component (GO:0006928)	2.61	5	KIRREL3, DYNC1H1, MEF2C, KIF1A, CTNNB1
positive regulation of developmental process (GO:0051094)	2.77	5	MEF2C, SOX11, CDH15, CTNNB1, ADNP
positive regulation of cell death (GO:0010942)	3.32	5	PPP2R1A, MEF2C, EEF1A2, GRIN1, CTNNB1
protein complex disassembly (GO:0043241)	4.58	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, CTNNB1
regulation of ion transport (GO:0043269)	3.4	5	MEF2C, CACNG2, GRIN1, CTNNB1, DPP6
positive regulation of apoptotic process (GO:0043065)	3.38	5	PPP2R1A, MEF2C, EEF1A2, GRIN1, CTNNB1
macromolecular complex disassembly (GO:0032984)	4.53	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, CTNNB1
negative regulation of neuron death (GO:1901215)	4.57	5	ADNP, MEF2C, GRIN1, CTNNB1, SYNGAP1
cellular macromolecule localization (GO:0070727)	3.1	5	CHAMP1, PACS1, SYNGAP1, CTNNB1, DPP6
regulation of anatomical structure morphogenesis (GO:0022603)	2.79	5	ADNP, MEF2C, GRIN1, CTNNB1, SYNGAP1
regulation of cell cycle process (GO:0010564)	3.5	5	PPP2R1A, SOX11, SMARCA4, CTNNB1, CTCF
positive regulation of protein metabolic process (GO:0051247)	2.43	5	ADNP, SMARCB1, CTNNB1, DYRK1A, AUTS2
peptidyl-amino acid modification (GO:0018193)	2.98	5	KMT2C, KANSL1, EHMT1, DYRK1A, KAT6A
interspecies interaction between organisms (GO:0044419)	3.08	5	ZMYND11, MEF2C, PACS1, SMARCB1, SMARCA4
regulation of neuron differentiation (GO:0045664)	3.39	5	MEF2C, ADNP, SOX11, GRIN1, SYNGAP1
animal organ development (GO:0048513)	2.53	5	KIRREL3, MEF2C, SOX11, KAT6A, CTNNB1
positive regulation of cellular protein metabolic process (GO:0032270)	2.49	5	DYRK1A, SMARCB1, AUTS2, CTNNB1, ADNP
regulation of immune system process (GO:0002682)	2.5	5	SOX11, MEF2C, PACS1, CTNNB1, MBD5
macromolecule localization (GO:0033036)	2.34	5	CHAMP1, PACS1, SYNGAP1, CTNNB1, DPP6
response to external stimulus (GO:0009605)	2.55	5	ADNP, MEF2C, GRIN1, CTNNB1, AUTS2
anatomical structure formation involved in morphogenesis (GO:0048646)	3.01	5	DEAF1, MEF2C, SOX11, ARID1A, CTNNB1
cell proliferation (GO:0008283)	3.23	5	ZMYND11, MEF2C, SOX11, COL4A3BP, CTNNB1
cellular protein localization (GO:0034613)	3.11	5	CHAMP1, PACS1, SYNGAP1, CTNNB1, DPP6
negative regulation of protein metabolic process (GO:0051248)	2.82	5	PPP2R1A, ZMYND11, SMARCB1, PURA, CTNNB1
positive regulation of cell differentiation (GO:0045597)	3.01	5	MEF2C, SOX11, CDH15, CTNNB1, ADNP
regulation of multi-organism process (GO:0043900)	3.6	5	PPP2R1A, SMARCB1, PACS1, SMARCA4, MBD5
establishment of localization in cell (GO:0051649)	2.47	5	DYNC1H1, KIF1A, PACS1, COL4A3BP, CTNNB1
regulation of neuron death (GO:1901214)	4.19	5	MEF2C, CTNNB1, GRIN1, SYNGAP1, ADNP
response to inorganic substance (GO:0010035)	3.56	5	GRIN1, MEF2C, EEF1A2, CTNNB1, ADNP
response to oxygen-containing compound (GO:1901700)	2.57	5	MEF2C, GRIN2B, GRIN1, CTNNB1, ADNP
response to abiotic stimulus (GO:0009628)	2.8	5	GRIN1, DEAF1, EEF1A2, SYNGAP1, CTNNB1
negative regulation of cellular protein metabolic process (GO:0032269)	2.88	5	PPP2R1A, ZMYND11, SMARCB1, PURA, CTNNB1
chromosome organization (GO:0051276)	3.79	5	PPP2R1A, KAT6A, PURA, POGZ, ARID1A
intracellular transport (GO:0046907)	2.67	5	DYNC1H1, KIF1A, PACS1, COL4A3BP, CTNNB1
regulation of cell cycle (GO:0051726)	2.93	5	PPP2R1A, SOX11, SMARCA4, CTNNB1, CTCF
regulation of response to stress (GO:0080134)	2.53	5	ZMYND11, MEF2C, PACS1, DYRK1A, MBD5
positive regulation of protein modification process (GO:0031401)	2.7	5	ADNP, SMARCB1, DYRK1A, CTNNB1, AUTS2
response to stress (GO:0006950)	1.8	5	DEAF1, MEF2C, SMARCB1, KAT6A, COL4A3BP
positive regulation of programmed cell death (GO:0043068)	3.38	5	PPP2R1A, MEF2C, EEF1A2, GRIN1, CTNNB1
regulation of neuron apoptotic process (GO:0043523)	4.47	5	MEF2C, CTNNB1, GRIN1, SYNGAP1, ADNP
DNA metabolic process (GO:0006259)	3.09	5	EHMT1, SMARCB1, PURA, GATAD2B, CTCF
regulation of protein phosphorylation (GO:0001932)	2.57	5	ZMYND11, PPP2R1A, ADNP, CTNNB1, SYNGAP1
regulation of chromatin organization (GO:1902275)	4.69	4	SMARCB1, AUTS2, CTNNB1, CTCF
regulation of chromosome organization (GO:0033044)	4.11	4	SMARCB1, AUTS2, CTNNB1, CTCF
cell communication (GO:0007154)	3.04	4	GRIN2B, GRIN1, CTNNB1, ADNP
mitotic cell cycle process (GO:1903047)	3.12	4	PPP2R1A, DYNC1H1, CHAMP1, POGZ
modulation of synaptic transmission (GO:0050804)	4.09	4	MEF2C, GRIN1, SYNGAP1, ADNP
membrane organization (GO:0061024)	3.04	4	PPP2R1A, PACS1, DPP6, SYNGAP1
cell cycle process (GO:0022402)	2.75	4	PPP2R1A, DYNC1H1, CHAMP1, POGZ
regulation of transferase activity (GO:0051338)	2.88	4	PPP2R1A, EEF1A2, ADNP, CTNNB1
cell surface receptor signaling pathway (GO:0007166)	2.09	4	MEF2C, CTNNB1, GRIN2B, GRIN1
regulation of histone modification (GO:0031056)	4.85	4	SMARCB1, AUTS2, CTNNB1, CTCF
signaling (GO:0023052)	3.25	4	GRIN2B, CACNG2, GRIN1, CTNNB1
regulation of ion transmembrane transport (GO:0034765)	3.77	4	MEF2C, CACNG2, GRIN1, DPP6
regulation of cell morphogenesis (GO:0022604)	3.4	4	GRIN1, ADNP, SYNGAP1, CTNNB1
positive regulation of neurogenesis (GO:0050769)	3.77	4	MEF2C, SOX11, ADNP, CTNNB1
single-organism membrane organization (GO:0044802)	3.19	4	PPP2R1A, PACS1, DPP6, SYNGAP1
regulation of cell projection organization (GO:0031344)	3.38	4	MEF2C, GRIN1, SYNGAP1, ADNP
signal transduction by protein phosphorylation (GO:0023014)	3.79	4	MEF2C, GRIN2B, GRIN1, SYNGAP1
regulation of MAPK cascade (GO:0043408)	3.22	4	PPP2R1A, ZMYND11, SYNGAP1, CTNNB1
protein-DNA complex disassembly (GO:0032986)	6.9	4	SMARCE1, SMARCB1, ARID1A, SMARCA4
positive regulation of hydrolase activity (GO:0051345)	2.91	4	MEF2C, GRIN2B, GRIN1, SYNGAP1
positive regulation of nervous system development (GO:0051962)	3.64	4	MEF2C, SOX11, ADNP, CTNNB1
positive regulation of phosphorus metabolic process (GO:0010562)	2.78	4	MEF2C, EEF1A2, CTNNB1, ADNP
negative regulation of multicellular organismal process (GO:0051241)	2.84	4	MEF2C, SOX11, SYNGAP1, CTNNB1
MAPK cascade (GO:0000165)	3.91	4	MEF2C, GRIN2B, GRIN1, SYNGAP1
regulation of gene expression, epigenetic (GO:0040029)	4.58	4	ARID1A, ARID1B, CTNNB1, CTCF
cellular component morphogenesis (GO:0032989)	3.5	4	KIRREL3, MEF2C, COL4A3BP, CTNNB1
regulation of cell morphogenesis involved in differentiation (GO:0010769)	3.91	4	GRIN1, ADNP, SYNGAP1, CTNNB1
histone modification (GO:0016570)	3.91	4	KMT2C, KANSL1, EHMT1, KAT6A
positive regulation of cell development (GO:0010720)	3.57	4	MEF2C, SOX11, ADNP, CTNNB1
transcription from RNA polymerase II promoter (GO:0006366)	3.38	4	MEF2C, SOX11, DEAF1, CTCF
methylation (GO:0032259)	4.06	4	EHMT1, KMT2C, GATAD2B, CTCF
positive regulation of cell proliferation (GO:0008284)	3.01	4	MEF2C, SOX11, CTNNB1, PURA
negative regulation of cell proliferation (GO:0008285)	3.26	4	MEF2C, SOX11, SMARCB1, CTNNB1
organ morphogenesis (GO:0009887)	3.55	4	MEF2C, SOX11, COL4A3BP, CTNNB1
cellular response to stress (GO:0033554)	2.51	4	MEF2C, SMARCB1, COL4A3BP, KAT6A
positive regulation of phosphate metabolic process (GO:0045937)	2.78	4	MEF2C, EEF1A2, CTNNB1, ADNP
regulation of viral process (GO:0050792)	3.89	4	SMARCB1, PACS1, SMARCA4, MBD5
tissue development (GO:0009888)	3.27	4	MEF2C, SOX11, ZBTB18, CTNNB1
regulation of histone methylation (GO:0031060)	5.65	4	SMARCB1, AUTS2, CTNNB1, CTCF
developmental process involved in reproduction (GO:0003006)	3.36	4	SMARCA4, DEAF1, ARID1A, CTNNB1
single-organism transport (GO:0044765)	2.18	4	PACS1, KIF1A, COL4A3BP, CTNNB1
regulation of cell growth (GO:0001558)	3.75	4	PPP2R1A, EPB41L1, ADNP, SMARCA4
macromolecule methylation (GO:0043414)	4.42	4	KMT2C, CTCF, GATAD2B, EHMT1
regulation of neuron projection development (GO:0010975)	3.69	4	MEF2C, GRIN1, SYNGAP1, ADNP
symbiosis, encompassing mutualism through parasitism (GO:0044403)	3.15	4	ZMYND11, MEF2C, PACS1, SMARCB1
negative regulation of intracellular signal transduction (GO:1902532)	3.63	4	PPP2R1A, ZMYND11, DYRK1A, SYNGAP1
regulation of epithelial cell proliferation (GO:0050678)	4.06	4	MEF2C, SOX11, DEAF1, CTNNB1
tube formation (GO:0035148)	4.98	4	ARID1A, SOX11, DEAF1, CTNNB1
single organism signaling (GO:0044700)	3.25	4	GRIN1, GRIN2B, CACNG2, CTNNB1
organonitrogen compound metabolic process (GO:1901564)	2.32	4	PPP2R1A, EEF1A2, SOX11, COL4A3BP
cellular amide metabolic process (GO:0043603)	3.23	4	PPP2R1A, EEF1A2, SOX11, COL4A3BP
regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903)	3.82	4	SMARCB1, PACS1, SMARCA4, MBD5
peptidyl-lysine modification (GO:0018205)	3.98	4	KMT2C, KANSL1, EHMT1, KAT6A
nucleosome disassembly (GO:0006337)	6.9	4	SMARCE1, SMARCB1, ARID1A, SMARCA4
negative regulation of protein modification process (GO:0031400)	3.4	4	PPP2R1A, ZMYND11, SMARCB1, CTNNB1
negative regulation of neuron apoptotic process (GO:0043524)	4.82	4	MEF2C, GRIN1, SYNGAP1, ADNP
chemical homeostasis (GO:0048878)	2.97	4	ADNP, GRIN1, MBD5, COL4A3BP
immune system process (GO:0002376)	2.29	4	DYNC1H1, MEF2C, COL4A3BP, CTNNB1
regulation of cellular component biogenesis (GO:0044087)	3.08	4	MEF2C, GRIN1, CTNNB1, ADNP
single-organism organelle organization (GO:1902589)	2.68	4	DYNC1H1, EPB41L1, COL4A3BP, MBD5
multi-organism cellular process (GO:0044764)	3.14	4	ZMYND11, MEF2C, PACS1, SMARCB1
viral process (GO:0016032)	3.15	4	ZMYND11, MEF2C, PACS1, SMARCB1
single-organism intracellular transport (GO:1902582)	3.59	4	KIF1A, PACS1, COL4A3BP, CTNNB1
regulation of transmembrane transport (GO:0034762)	3.74	4	MEF2C, CACNG2, GRIN1, DPP6
positive regulation of cellular component organization (GO:0051130)	2.68	4	SMARCB1, AUTS2, CTNNB1, ADNP
positive regulation of multicellular organismal process (GO:0051240)	2.49	4	MEF2C, SOX11, ADNP, CTNNB1
covalent chromatin modification (GO:0016569)	3.89	4	EHMT1, KANSL1, KMT2C, KAT6A
regulation of histone acetylation (GO:0035065)	5.74	3	SMARCB1, CTCF, AUTS2
regulation of apoptotic signaling pathway (GO:2001233)	3.83	3	PPP2R1A, ZMYND11, CTNNB1
learning (GO:0007612)	4.85	3	DEAF1, GRIN1, SYNGAP1
positive regulation of homeostatic process (GO:0032846)	4.38	3	SMARCB1, SMARCA4, CTNNB1
regulation of homeostatic process (GO:0032844)	3.65	3	SMARCB1, SMARCA4, CTNNB1
skeletal system development (GO:0001501)	4.49	3	DEAF1, SOX11, CTNNB1
positive regulation of histone modification (GO:0031058)	5.32	3	SMARCB1, AUTS2, CTNNB1
regulation of defense response (GO:0031347)	3.11	3	MEF2C, PACS1, MBD5
hormone-mediated signaling pathway (GO:0009755)	4.66	3	NR1I3, ARID1A, CTNNB1
DNA methylation (GO:0006306)	5.92	3	EHMT1, CTCF, GATAD2B
DNA alkylation (GO:0006305)	5.92	3	EHMT1, CTCF, GATAD2B
DNA modification (GO:0006304)	5.36	3	EHMT1, CTCF, GATAD2B
negative regulation of cell cycle (GO:0045786)	3.67	3	SOX11, SMARCA4, CTNNB1
rhythmic process (GO:0048511)	4.02	3	ADNP, GRIN1, DYRK1A
regulation of osteoblast differentiation (GO:0045667)	4.99	3	MEF2C, SOX11, CTNNB1
positive regulation of neuron differentiation (GO:0045666)	3.98	3	MEF2C, SOX11, ADNP
negative regulation of molecular function (GO:0044092)	2.74	3	PPP2R1A, ADNP, SOX11
regulation of signal transduction by p53 class mediator (GO:1901796)	4.63	3	EHMT1, KAT6A, DYRK1A
positive regulation of osteoblast differentiation (GO:0045669)	5.62	3	MEF2C, SOX11, CTNNB1
(GO:1905269)	5.25	3	SMARCB1, AUTS2, CTNNB1
germ cell development (GO:0007281)	4.75	3	DEAF1, SMARCA4, CTNNB1
cell adhesion (GO:0007155)	2.82	3	KIRREL3, CDH15, CTNNB1
protein localization to membrane (GO:0072657)	3.95	3	PACS1, DPP6, SYNGAP1
response to metal ion (GO:0010038)	3.91	3	MEF2C, GRIN1, CTNNB1
intracellular steroid hormone receptor signaling pathway (GO:0030518)	5.47	3	NR1I3, ARID1A, CTNNB1
positive regulation of phosphorylation (GO:0042327)	2.9	3	EEF1A2, ADNP, CTNNB1
vesicle-mediated transport (GO:0016192)	2.72	3	DYNC1H1, PACS1, CTNNB1
organonitrogen compound biosynthetic process (GO:1901566)	2.85	3	EEF1A2, SOX11, COL4A3BP
cell motility (GO:0048870)	3.02	3	KIRREL3, MEF2C, CTNNB1
response to organonitrogen compound (GO:0010243)	3.2	3	MEF2C, GRIN1, CTNNB1
positive regulation of organelle organization (GO:0010638)	3.38	3	SMARCB1, AUTS2, CTNNB1
anterograde trans-synaptic signaling (GO:0098916)	3.98	3	GRIN2B, GRIN1, CTNNB1
epithelial cell differentiation (GO:0030855)	3.98	3	MEF2C, SOX11, CTNNB1
muscle cell differentiation (GO:0042692)	5.09	3	MEF2C, ARID1A, CTNNB1
regulation of membrane potential (GO:0042391)	3.89	3	MEF2C, CACNG2, GRIN1
visual behavior (GO:0007632)	5.82	3	DEAF1, GRIN1, SYNGAP1
embryonic organ morphogenesis (GO:0048562)	4.92	3	MEF2C, SOX11, CTNNB1
steroid hormone mediated signaling pathway (GO:0043401)	4.9	3	NR1I3, ARID1A, CTNNB1
regulation of synaptic plasticity (GO:0048167)	4.78	3	MEF2C, GRIN1, SYNGAP1
neuron migration (GO:0001764)	5.0	3	KIRREL3, MEF2C, CTNNB1
regulation of mononuclear cell proliferation (GO:0032944)	4.45	3	MEF2C, SOX11, CTNNB1
positive regulation of transferase activity (GO:0051347)	3.31	3	EEF1A2, ADNP, CTNNB1
positive regulation of GTPase activity (GO:0043547)	3.28	3	GRIN2B, GRIN1, SYNGAP1
regulation of kinase activity (GO:0043549)	3.07	3	PPP2R1A, EEF1A2, ADNP
response to organic cyclic compound (GO:0014070)	3.07	3	MEF2C, GRIN1, CTNNB1
regulation of ossification (GO:0030278)	4.53	3	MEF2C, SOX11, CTNNB1
cell migration (GO:0016477)	3.12	3	KIRREL3, MEF2C, CTNNB1
skeletal system morphogenesis (GO:0048705)	4.98	3	MEF2C, SOX11, CTNNB1
embryonic skeletal system morphogenesis (GO:0048704)	5.31	3	MEF2C, SOX11, CTNNB1
chromatin-mediated maintenance of transcription (GO:0048096)	7.65	3	ARID1A, ARID1B, CTNNB1
cell-cell adhesion (GO:0098609)	3.34	3	KIRREL3, CDH15, CTNNB1
ion transport (GO:0006811)	2.66	3	GRIN2B, CACNG2, GRIN1
DNA methylation or demethylation (GO:0044728)	5.65	3	EHMT1, CTCF, GATAD2B
regulation of protein binding (GO:0043393)	4.6	3	MEF2C, PACS1, ADNP
regulation of protein acetylation (GO:1901983)	5.59	3	SMARCB1, CTCF, AUTS2
regulation of dephosphorylation (GO:0035303)	4.67	3	PPP2R1A, MEF2C, PPP2R5D
response to nitrogen compound (GO:1901698)	3.12	3	MEF2C, GRIN1, CTNNB1
regulation of synapse assembly (GO:0051963)	5.36	3	MEF2C, ADNP, GRIN1
regulation of leukocyte activation (GO:0002694)	3.6	3	MEF2C, SOX11, CTNNB1
negative regulation of nervous system development (GO:0051961)	4.15	3	SOX11, SYNGAP1, CTNNB1
associative learning (GO:0008306)	5.44	3	DEAF1, GRIN1, SYNGAP1
positive regulation of chromosome organization (GO:2001252)	4.76	3	SMARCB1, AUTS2, CTNNB1
synaptic signaling (GO:0099536)	3.98	3	GRIN2B, GRIN1, CTNNB1
trans-synaptic signaling (GO:0099537)	3.98	3	GRIN2B, GRIN1, CTNNB1
regulation of developmental growth (GO:0048638)	4.04	3	MEF2C, ADNP, MBD5
synapse organization (GO:0050808)	4.87	3	KIRREL3, CACNG2, CTNNB1
cellular response to metal ion (GO:0071248)	4.81	3	MEF2C, GRIN1, CTNNB1
regulation of response to external stimulus (GO:0032101)	3.06	3	PACS1, GRIN1, MBD5
regulation of synapse structure or activity (GO:0050803)	4.77	3	MEF2C, GRIN1, SYNGAP1
regulation of phosphatase activity (GO:0010921)	4.88	3	PPP2R1A, MEF2C, PPP2R5D
chemical synaptic transmission (GO:0007268)	3.98	3	GRIN2B, GRIN1, CTNNB1
regulation of synapse organization (GO:0050807)	5.03	3	MEF2C, ADNP, GRIN1
cellular response to inorganic substance (GO:0071241)	4.67	3	MEF2C, GRIN1, CTNNB1
negative regulation of cellular component organization (GO:0051129)	3.35	3	SMARCB1, CTNNB1, SYNGAP1
embryo development (GO:0009790)	4.2	3	EHMT1, COL4A3BP, CTNNB1
response to light stimulus (GO:0009416)	4.08	3	DEAF1, GRIN1, SYNGAP1
cellular response to chemical stimulus (GO:0070887)	2.57	3	MEF2C, GRIN1, CTNNB1
regulation of GTPase activity (GO:0043087)	3.21	3	GRIN2B, GRIN1, SYNGAP1
visual learning (GO:0008542)	5.92	3	DEAF1, GRIN1, SYNGAP1
cell cycle (GO:0007049)	3.14	3	ZMYND11, SMARCB1, POGZ
response to endogenous stimulus (GO:0009719)	2.79	3	MEF2C, GRIN1, CTNNB1
regulation of lymphocyte activation (GO:0051249)	3.73	3	MEF2C, SOX11, CTNNB1
negative regulation of neurogenesis (GO:0050768)	4.22	3	SOX11, SYNGAP1, CTNNB1
biological adhesion (GO:0022610)	2.81	3	KIRREL3, CDH15, CTNNB1
negative regulation of cell development (GO:0010721)	4.02	3	SOX11, SYNGAP1, CTNNB1
negative regulation of cell differentiation (GO:0045596)	3.33	3	SOX11, CTNNB1, SYNGAP1
transmembrane transport (GO:0055085)	2.72	3	GRIN2B, CACNG2, GRIN1
negative regulation of developmental process (GO:0051093)	3.17	3	SOX11, CTNNB1, SYNGAP1
positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091)	4.29	3	SMARCB1, SMARCA4, CTNNB1
regulation of sequence-specific DNA binding transcription factor activity (GO:0051090)	3.83	3	SMARCB1, SMARCA4, CTNNB1
regulation of axonogenesis (GO:0050770)	4.59	3	ADNP, GRIN1, SYNGAP1
regulation of lymphocyte proliferation (GO:0050670)	4.46	3	MEF2C, SOX11, CTNNB1
myeloid cell differentiation (GO:0030099)	4.63	3	MEF2C, KAT6A, CTNNB1
protein localization to organelle (GO:0033365)	3.57	3	CHAMP1, PACS1, CTNNB1
regulation of cell activation (GO:0050865)	3.53	3	MEF2C, SOX11, CTNNB1
regulation of muscle cell differentiation (GO:0051147)	4.68	3	MEF2C, CDH15, CTNNB1
cellular macromolecular complex assembly (GO:0034622)	3.18	3	DYNC1H1, KAT6A, POGZ
positive regulation of muscle cell differentiation (GO:0051149)	5.26	3	MEF2C, CDH15, CTNNB1
morphogenesis of an epithelium (GO:0002009)	4.08	3	MEF2C, SOX11, CTNNB1
intracellular receptor signaling pathway (GO:0030522)	4.6	3	NR1I3, ARID1A, CTNNB1
androgen receptor signaling pathway (GO:0030521)	6.02	3	NR1I3, ARID1A, CTNNB1
response to radiation (GO:0009314)	3.69	3	DEAF1, GRIN1, SYNGAP1
regulation of leukocyte proliferation (GO:0070663)	4.4	3	MEF2C, SOX11, CTNNB1
tissue morphogenesis (GO:0048729)	3.87	3	MEF2C, SOX11, CTNNB1
organic substance transport (GO:0071702)	2.15	3	PACS1, COL4A3BP, CTNNB1
positive regulation of gene expression, epigenetic (GO:0045815)	5.76	3	ARID1A, ARID1B, CTNNB1
embryonic morphogenesis (GO:0048598)	3.72	3	MEF2C, SOX11, CTNNB1
neuron differentiation (GO:0030182)	4.17	3	MEF2C, SOX11, CTNNB1
pattern specification process (GO:0007389)	3.79	3	MEF2C, SYNGAP1, CTNNB1
ion transmembrane transport (GO:0034220)	3.08	3	GRIN2B, CACNG2, GRIN1
cellular process involved in reproduction in multicellular organism (GO:0022412)	4.3	3	DEAF1, SMARCA4, CTNNB1
cell-cell signaling (GO:0007267)	3.35	3	GRIN2B, GRIN1, CTNNB1
cell morphogenesis (GO:0000902)	4.35	3	MEF2C, COL4A3BP, CTNNB1
locomotion (GO:0040011)	2.91	3	KIRREL3, MEF2C, CTNNB1
microtubule-based process (GO:0007017)	3.54	3	PPP2R1A, DYNC1H1, KIF1A
positive regulation of ossification (GO:0045778)	5.27	3	MEF2C, SOX11, CTNNB1
response to alcohol (GO:0097305)	4.58	3	GRIN2B, GRIN1, CTNNB1
regulation of peptidyl-lysine acetylation (GO:2000756)	5.67	3	SMARCB1, CTCF, AUTS2
negative regulation of apoptotic signaling pathway (GO:2001234)	4.42	2	ZMYND11, CTNNB1
protein methylation (GO:0006479)	4.96	2	EHMT1, KMT2C
regulation of extrinsic apoptotic signaling pathway (GO:2001236)	4.69	2	PPP2R1A, ZMYND11
regulation of defense response to virus (GO:0050688)	4.53	2	PACS1, MBD5
regulation of secretion (GO:0051046)	3.2	2	MEF2C, SOX11
G2/M transition of mitotic cell cycle (GO:0000086)	4.84	2	PPP2R1A, DYNC1H1
protein dephosphorylation (GO:0006470)	4.47	2	PPP2R1A, PPP2R5D
protein acetylation (GO:0006473)	4.86	2	KAT6A, KANSL1
regulation of reproductive process (GO:2000241)	4.88	2	PPP2R1A, CTNNB1
internal protein amino acid acetylation (GO:0006475)	4.99	2	KANSL1, KAT6A
memory (GO:0007613)	5.13	2	ADNP, GRIN1
regulation of histone H4-K16 acetylation (GO:2000618)	7.94	2	SMARCB1, AUTS2
positive regulation of histone H4 acetylation (GO:0090240)	7.94	2	SMARCB1, AUTS2
regulation of Wnt signaling pathway (GO:0030111)	3.98	2	PPP2R1A, SMARCA4
regulation of histone H3-K4 methylation (GO:0051569)	6.36	2	AUTS2, CTNNB1
enzyme linked receptor protein signaling pathway (GO:0007167)	3.24	2	GRIN2B, GRIN1
transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)	3.54	2	GRIN2B, GRIN1
establishment of organelle localization (GO:0051656)	4.15	2	DYNC1H1, CTNNB1
mitochondrion organization (GO:0007005)	3.69	2	COL4A3BP, MBD5
positive regulation of cell morphogenesis involved in differentiation (GO:0010770)	4.65	2	ADNP, CTNNB1
outflow tract morphogenesis (GO:0003151)	5.97	2	MEF2C, SOX11
positive regulation of histone acetylation (GO:0035066)	6.33	2	SMARCB1, AUTS2
skeletal muscle tissue development (GO:0007519)	5.65	2	MEF2C, ZBTB18
kidney development (GO:0001822)	4.79	2	SOX11, CTNNB1
glutamate receptor signaling pathway (GO:0007215)	5.99	2	GRIN2B, GRIN1
chromosome segregation (GO:0007059)	5.06	2	PPP2R1A, CTCF
modification of morphology or physiology of other organism involved in symbiotic interaction (GO:0051817)	5.27	2	SMARCB1, SMARCA4
cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)	4.39	2	KIRREL3, CDH15
response to fungicide (GO:0060992)	7.24	2	EHMT1, GRIN1
sphingolipid metabolic process (GO:0006665)	4.79	2	PPP2R1A, COL4A3BP
regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122)	4.27	2	ZMYND11, CTNNB1
negative regulation of immune system process (GO:0002683)	3.85	2	SOX11, CTNNB1
regulation of striated muscle tissue development (GO:0016202)	5.09	2	MEF2C, CTNNB1
regulation of DNA metabolic process (GO:0051052)	3.87	2	PPP2R1A, CTNNB1
positive regulation of transport (GO:0051050)	2.9	2	SOX11, DPP6
regulation of protein kinase activity (GO:0045859)	3.15	2	PPP2R1A, ADNP
regulation of glycoprotein metabolic process (GO:1903018)	5.97	2	ADNP, CTNNB1
response to calcium ion (GO:0051592)	4.98	2	MEF2C, GRIN1
regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter (GO:1901836)	7.53	2	SMARCB1, SMARCA4
lymphocyte activation (GO:0046649)	3.96	2	MEF2C, CTNNB1
regionalization (GO:0003002)	4.24	2	MEF2C, CTNNB1
positive regulation of histone methylation (GO:0031062)	6.2	2	AUTS2, CTNNB1
regulation of skeletal muscle tissue development (GO:0048641)	5.78	2	MEF2C, CTNNB1
interaction with symbiont (GO:0051702)	5.76	2	SMARCB1, SMARCA4
regulation of glucose mediated signaling pathway (GO:1902659)	8.34	2	SMARCB1, SMARCA4
regulation of hemopoiesis (GO:1903706)	4.0	2	MEF2C, CTNNB1
epithelial tube morphogenesis (GO:0060562)	5.12	2	MEF2C, CTNNB1
multi-organism behavior (GO:0051705)	5.6	2	KIRREL3, GRIN1
amide biosynthetic process (GO:0043604)	3.6	2	EEF1A2, SOX11
negative regulation of phosphorylation (GO:0042326)	3.7	2	PPP2R1A, ZMYND11
histone acetylation (GO:0016573)	5.09	2	KAT6A, KANSL1
cardiac ventricle formation (GO:0003211)	7.43	2	MEF2C, SOX11
regulation of peptidyl-tyrosine phosphorylation (GO:0050730)	4.35	2	PPP2R1A, ADNP
calcium ion transmembrane transport (GO:0070588)	4.67	2	CACNG2, GRIN1
muscle system process (GO:0003012)	4.18	2	MEF2C, COL4A3BP
response to hormone (GO:0009725)	3.33	2	MEF2C, CTNNB1
establishment of protein localization (GO:0045184)	2.53	2	PACS1, CTNNB1
ceramide metabolic process (GO:0006672)	5.41	2	PPP2R1A, COL4A3BP
regulation of neurotransmitter receptor activity (GO:0099601)	6.29	2	MEF2C, CACNG2
DNA conformation change (GO:0071103)	4.9	2	KAT6A, PURA
regulation of muscle tissue development (GO:1901861)	5.07	2	MEF2C, CTNNB1
positive regulation of striated muscle tissue development (GO:0045844)	5.69	2	MEF2C, CTNNB1
regulation of ion transmembrane transporter activity (GO:0032412)	4.55	2	MEF2C, CACNG2
positive regulation of kinase activity (GO:0033674)	3.54	2	EEF1A2, ADNP
regulation of response to biotic stimulus (GO:0002831)	4.3	2	PACS1, MBD5
negative regulation of binding (GO:0051100)	4.85	2	ADNP, SOX11
leukocyte activation (GO:0045321)	3.76	2	MEF2C, CTNNB1
peptide biosynthetic process (GO:0043043)	3.73	2	EEF1A2, SOX11
regulation of long-term neuronal synaptic plasticity (GO:0048169)	6.55	2	GRIN1, SYNGAP1
positive regulation of viral transcription (GO:0050434)	6.07	2	SMARCB1, SMARCA4
beta-catenin-TCF complex assembly (GO:1904837)	6.33	2	SMARCA4, CTNNB1
sister chromatid cohesion (GO:0007062)	5.03	2	PPP2R1A, POGZ
negative regulation of gliogenesis (GO:0014014)	6.09	2	SOX11, CTNNB1
protein acylation (GO:0043543)	4.65	2	KANSL1, KAT6A
cardiac chamber formation (GO:0003207)	7.33	2	MEF2C, SOX11
cell morphogenesis involved in differentiation (GO:0000904)	4.67	2	MEF2C, CTNNB1
regulation of gliogenesis (GO:0014013)	5.21	2	SOX11, CTNNB1
blood vessel development (GO:0001568)	4.95	2	MEF2C, ARID1A
negative regulation of phosphate metabolic process (GO:0045936)	3.45	2	PPP2R1A, ZMYND11
peptidyl-lysine methylation (GO:0018022)	5.42	2	EHMT1, KMT2C
homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)	4.68	2	KIRREL3, CDH15
histone methylation (GO:0016571)	5.3	2	EHMT1, KMT2C
inorganic cation transmembrane transport (GO:0098662)	3.55	2	CACNG2, GRIN1
positive regulation of stem cell proliferation (GO:2000648)	6.07	2	SOX11, CTNNB1
inorganic ion transmembrane transport (GO:0098660)	3.38	2	CACNG2, GRIN1
skeletal muscle cell differentiation (GO:0035914)	5.74	2	MEF2C, SOX11
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (GO:2000311)	6.78	2	MEF2C, CACNG2
neural tube closure (GO:0001843)	5.38	2	ARID1A, DEAF1
positive regulation of skeletal muscle tissue development (GO:0048643)	6.43	2	MEF2C, CTNNB1
internal peptidyl-lysine acetylation (GO:0018393)	5.05	2	KANSL1, KAT6A
positive regulation of muscle tissue development (GO:1901863)	5.67	2	MEF2C, CTNNB1
lipid metabolic process (GO:0006629)	2.68	2	PPP2R1A, COL4A3BP
peptidyl-lysine acetylation (GO:0018394)	5.03	2	KANSL1, KAT6A
cation transport (GO:0006812)	3.11	2	CACNG2, GRIN1
calcium ion transport (GO:0006816)	4.33	2	CACNG2, GRIN1
tube closure (GO:0060606)	5.36	2	ARID1A, DEAF1
programmed cell death (GO:0012501)	3.1	2	PPP2R1A, MEF2C
cell activation (GO:0001775)	3.47	2	MEF2C, CTNNB1
positive regulation of protein acetylation (GO:1901985)	6.15	2	SMARCB1, AUTS2
muscle tissue development (GO:0060537)	5.1	2	MEF2C, ZBTB18
excitatory postsynaptic potential (GO:0060079)	6.43	2	MEF2C, GRIN1
regulation of postsynaptic membrane potential (GO:0060078)	5.72	2	MEF2C, GRIN1
ephrin receptor signaling pathway (GO:0048013)	5.29	2	GRIN2B, GRIN1
regulation of protein dephosphorylation (GO:0035304)	5.31	2	PPP2R1A, PPP2R5D
negative regulation of cell cycle phase transition (GO:1901988)	4.74	2	SOX11, SMARCA4
modification of morphology or physiology of other organism (GO:0035821)	5.12	2	SMARCB1, SMARCA4
positive regulation of multi-organism process (GO:0043902)	4.68	2	SMARCB1, SMARCA4
modulation of transcription in other organism involved in symbiotic interaction (GO:0052312)	6.64	2	SMARCB1, SMARCA4
regulation of glutamate receptor signaling pathway (GO:1900449)	6.36	2	MEF2C, CACNG2
regulation of phosphoprotein phosphatase activity (GO:0043666)	5.65	2	PPP2R1A, PPP2R5D
regulation of cell cycle phase transition (GO:1901987)	4.15	2	SOX11, SMARCA4
regulation of transmembrane transporter activity (GO:0022898)	4.52	2	MEF2C, CACNG2
regulation of cellular response to stress (GO:0080135)	3.4	2	ZMYND11, DYRK1A
glial cell proliferation (GO:0014009)	7.43	2	SOX11, CTNNB1
adherens junction organization (GO:0034332)	5.48	2	CDH15, CTNNB1
regulation of transcription from RNA polymerase I promoter (GO:0006356)	6.59	2	SMARCB1, SMARCA4
cellular response to oxygen-containing compound (GO:1901701)	3.22	2	MEF2C, CTNNB1
peptide metabolic process (GO:0006518)	3.44	2	EEF1A2, SOX11
regulation of glycoprotein biosynthetic process (GO:0010559)	6.09	2	ADNP, CTNNB1
regulation of myeloid cell differentiation (GO:0045637)	4.56	2	MEF2C, CTNNB1
positive regulation of developmental growth (GO:0048639)	4.67	2	MEF2C, ADNP
regulation of sister chromatid segregation (GO:0033045)	5.63	2	CTCF, CTNNB1
cell fate determination (GO:0001709)	5.97	2	MEF2C, CTNNB1
negative regulation of cell growth (GO:0030308)	4.58	2	PPP2R1A, SMARCA4
dephosphorylation (GO:0016311)	4.06	2	PPP2R1A, PPP2R5D
regulation of cytoskeleton organization (GO:0051493)	3.72	2	MEF2C, CTNNB1
regulation of cell adhesion (GO:0030155)	3.27	2	PPP2R1A, CTNNB1
immune response (GO:0006955)	2.86	2	MEF2C, COL4A3BP
epithelial tube formation (GO:0072175)	6.36	2	SOX11, CTNNB1
regulation of muscle organ development (GO:0048634)	5.07	2	MEF2C, CTNNB1
positive regulation of muscle organ development (GO:0048636)	5.69	2	MEF2C, CTNNB1
cellular catabolic process (GO:0044248)	2.62	2	PPP2R1A, CTNNB1
embryo development ending in birth or egg hatching (GO:0009792)	4.35	2	COL4A3BP, CTNNB1
regulation of secretion by cell (GO:1903530)	3.28	2	MEF2C, SOX11
positive regulation of protein binding (GO:0032092)	5.42	2	MEF2C, PACS1
positive regulation of intracellular signal transduction (GO:1902533)	2.95	2	SOX11, CTNNB1
mitotic cell cycle phase transition (GO:0044772)	4.27	2	PPP2R1A, DYNC1H1
protein localization to cell periphery (GO:1990778)	4.91	2	PACS1, DPP6
response to growth factor (GO:0070848)	4.14	2	MEF2C, CTNNB1
negative regulation of MAPK cascade (GO:0043409)	4.74	2	PPP2R1A, ZMYND11
regulation of cellular response to growth factor stimulus (GO:0090287)	4.29	2	SOX11, CTNNB1
in utero embryonic development (GO:0001701)	4.4	2	COL4A3BP, CTNNB1
regulation of viral life cycle (GO:1903900)	4.6	2	SMARCB1, SMARCA4
regulation of centromeric sister chromatid cohesion (GO:0070602)	8.63	2	CTCF, CTNNB1
positive regulation of viral life cycle (GO:1903902)	5.26	2	SMARCB1, SMARCA4
negative regulation of phosphorus metabolic process (GO:0010563)	3.45	2	PPP2R1A, ZMYND11
histone lysine methylation (GO:0034968)	5.57	2	KMT2C, EHMT1
modification by host of symbiont morphology or physiology (GO:0051851)	5.8	2	SMARCB1, SMARCA4
regulation of transporter activity (GO:0032409)	4.45	2	MEF2C, CACNG2
regulation of viral transcription (GO:0046782)	5.62	2	SMARCB1, SMARCA4
regulation of mitotic cell cycle (GO:0007346)	3.71	2	SMARCA4, CTNNB1
proteolysis (GO:0006508)	2.73	2	DPP6, CTNNB1
chordate embryonic development (GO:0043009)	4.38	2	COL4A3BP, CTNNB1
regulation of stem cell proliferation (GO:0072091)	5.6	2	SOX11, CTNNB1
cellular response to endogenous stimulus (GO:0071495)	3.33	2	MEF2C, CTNNB1
glomerulus morphogenesis (GO:0072102)	8.34	2	KIRREL3, MEF2C
cellular response to external stimulus (GO:0071496)	4.2	2	ADNP, CTNNB1
tube morphogenesis (GO:0035239)	4.35	2	MEF2C, CTNNB1
multicellular organismal reproductive process (GO:0048609)	3.35	2	ADNP, GRIN1
cardiac muscle cell differentiation (GO:0055007)	6.29	2	MEF2C, ARID1A
ionotropic glutamate receptor signaling pathway (GO:0035235)	6.55	2	GRIN2B, GRIN1
establishment of protein localization to organelle (GO:0072594)	3.92	2	PACS1, CTNNB1
epithelium development (GO:0060429)	4.57	2	SOX11, CTNNB1
regulation of neuronal synaptic plasticity (GO:0048168)	5.84	2	GRIN1, SYNGAP1
cellular response to hormone stimulus (GO:0032870)	3.99	2	MEF2C, CTNNB1
cell fate commitment (GO:0045165)	4.72	2	MEF2C, CTNNB1
metal ion transport (GO:0030001)	3.36	2	CACNG2, GRIN1
modulation by host of viral transcription (GO:0043921)	6.68	2	SMARCB1, SMARCA4
cell-cell junction organization (GO:0045216)	4.66	2	CDH15, CTNNB1
positive regulation by host of viral transcription (GO:0043923)	7.24	2	SMARCB1, SMARCA4
divalent metal ion transport (GO:0070838)	4.15	2	CACNG2, GRIN1
cellular lipid metabolic process (GO:0044255)	2.92	2	PPP2R1A, COL4A3BP
regulation of chromosome segregation (GO:0051983)	5.38	2	CTCF, CTNNB1
protein oligomerization (GO:0051259)	3.71	2	GRIN1, CTNNB1
protein alkylation (GO:0008213)	4.96	2	EHMT1, KMT2C
regulation of DNA binding (GO:0051101)	5.21	2	SOX11, CTNNB1
cellular response to growth factor stimulus (GO:0071363)	4.27	2	MEF2C, CTNNB1
positive regulation of epithelial cell proliferation (GO:0050679)	4.67	2	SOX11, CTNNB1
regulation of dendrite development (GO:0050773)	4.93	2	MEF2C, GRIN1
cellular response to organic cyclic compound (GO:0071407)	3.93	2	MEF2C, CTNNB1
positive regulation of binding (GO:0051099)	4.88	2	MEF2C, PACS1
response to drug (GO:0042493)	3.71	2	MEF2C, CTNNB1
negative regulation of cell cycle process (GO:0010948)	4.37	2	SOX11, SMARCA4
regulation of transcription regulatory region DNA binding (GO:2000677)	6.12	2	SOX11, CTNNB1
positive regulation of transcription from RNA polymerase I promoter (GO:0045943)	7.09	2	SMARCB1, SMARCA4
negative regulation of cell morphogenesis involved in differentiation (GO:0010771)	4.96	2	SYNGAP1, CTNNB1
hemopoiesis (GO:0030097)	5.07	2	KIRREL3, CTNNB1
cellular response to nitrogen compound (GO:1901699)	3.79	2	MEF2C, CTNNB1
negative regulation of growth (GO:0045926)	4.24	2	PPP2R1A, SMARCA4
positive regulation of growth (GO:0045927)	4.25	2	MEF2C, ADNP
cell cycle G2/M phase transition (GO:0044839)	4.82	2	PPP2R1A, DYNC1H1
cell projection organization (GO:0030030)	3.14	2	KIRREL3, SYNGAP1
divalent inorganic cation transport (GO:0072511)	4.13	2	CACNG2, GRIN1
cell junction organization (GO:0034330)	4.51	2	CDH15, CTNNB1
cell cycle phase transition (GO:0044770)	4.24	2	PPP2R1A, DYNC1H1
striated muscle tissue development (GO:0014706)	5.23	2	MEF2C, ZBTB18
smooth muscle cell differentiation (GO:0051145)	6.68	2	MEF2C, CTNNB1
protein transport (GO:0015031)	2.62	2	PACS1, CTNNB1
modulation by host of symbiont transcription (GO:0052472)	6.68	2	SMARCB1, SMARCA4
striated muscle cell differentiation (GO:0051146)	5.69	2	MEF2C, ARID1A
lens morphogenesis in camera-type eye (GO:0002089)	7.16	2	SOX11, CTNNB1
cell death (GO:0008219)	3.05	2	PPP2R1A, MEF2C
positive regulation of glucose mediated signaling pathway (GO:1902661)	8.63	2	SMARCB1, SMARCA4
osteoblast differentiation (GO:0001649)	5.05	2	NR1I3, MEF2C
membrane lipid metabolic process (GO:0006643)	4.51	2	PPP2R1A, COL4A3BP
leukocyte differentiation (GO:0002521)	4.13	2	MEF2C, CTNNB1
developmental maturation (GO:0021700)	4.7	2	GRIN1, CTNNB1
cellular response to organonitrogen compound (GO:0071417)	3.87	2	MEF2C, CTNNB1
positive regulation of protein phosphorylation (GO:0001934)	2.95	2	ADNP, CTNNB1
response to toxic substance (GO:0009636)	4.88	2	EHMT1, GRIN1
regulation of immune effector process (GO:0002697)	3.71	2	PACS1, MBD5
myeloid leukocyte differentiation (GO:0002573)	5.23	2	MEF2C, CTNNB1
cellular response to organic substance (GO:0071310)	2.78	2	MEF2C, CTNNB1
regulation of sister chromatid cohesion (GO:0007063)	6.9	2	CTCF, CTNNB1
regulation of histone H4 acetylation (GO:0090239)	7.33	2	SMARCB1, AUTS2
hematopoietic or lymphoid organ development (GO:0048534)	4.49	2	KIRREL3, CTNNB1
regulation of receptor activity (GO:0010469)	4.98	2	MEF2C, CACNG2
negative regulation of mitotic cell cycle (GO:0045930)	4.45	2	SMARCA4, CTNNB1
regulation of protein phosphatase type 2A activity (GO:0034047)	6.55	2	PPP2R1A, PPP2R5D
Golgi vesicle transport (GO:0048193)	4.07	2	DYNC1H1, PACS1
apoptotic process (GO:0006915)	3.14	2	PPP2R1A, MEF2C
cardiocyte differentiation (GO:0035051)	6.02	2	MEF2C, ARID1A
organic substance catabolic process (GO:1901575)	2.45	2	PPP2R1A, CTNNB1
regulation of cellular localization (GO:0060341)	3.03	2	MEF2C, CTNNB1
regulation of metal ion transport (GO:0010959)	3.94	2	DPP6, CTNNB1
response to ethanol (GO:0045471)	4.83	2	GRIN2B, GRIN1
cellular macromolecule catabolic process (GO:0044265)	3.19	2	PPP2R1A, CTNNB1
positive regulation of histone H3-K4 methylation (GO:0051571)	6.9	2	AUTS2, CTNNB1
organelle assembly (GO:0070925)	3.75	2	DYNC1H1, POGZ
catabolic process (GO:0009056)	2.38	2	PPP2R1A, CTNNB1
macromolecule catabolic process (GO:0009057)	3.0	2	PPP2R1A, CTNNB1
organelle localization (GO:0051640)	3.94	2	DYNC1H1, CTNNB1
embryonic epithelial tube formation (GO:0001838)	6.4	2	SOX11, CTNNB1
heart development (GO:0007507)	4.24	2	MEF2C, CTNNB1
cytoskeleton organization (GO:0007010)	3.22	2	DYNC1H1, EPB41L1
cell part morphogenesis (GO:0032990)	3.99	2	KIRREL3, COL4A3BP
microtubule-based movement (GO:0007018)	4.39	2	DYNC1H1, KIF1A
translation (GO:0006412)	3.79	2	EEF1A2, SOX11
forebrain development (GO:0030900)	5.48	2	ARID1A, CTNNB1
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter (GO:1901838)	7.94	2	SMARCB1, SMARCA4
response to lipid (GO:0033993)	3.11	2	MEF2C, CTNNB1
positive regulation of peptidyl-lysine acetylation (GO:2000758)	6.29	2	SMARCB1, AUTS2
positive regulation of viral process (GO:0048524)	5.11	2	SMARCB1, SMARCA4
negative regulation of protein phosphorylation (GO:0001933)	3.79	2	PPP2R1A, ZMYND11
cation transmembrane transport (GO:0098655)	3.43	2	CACNG2, GRIN1
intracellular protein transport (GO:0006886)	3.2	2	PACS1, CTNNB1
positive regulation of cellular component biogenesis (GO:0044089)	3.71	2	ADNP, CTNNB1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
nucleosome organization (GO:0034728)	-	4.79	0.0	CTCF, SMARCB1, SMARCE1, KAT6A, SMARCA4, ARID1A
regulation of chromosome organization (GO:0033044)	-	4.11	0.01	CTNNB1, CTCF, SETD5, SMARCE1, DYRK1A, PPP2R1A, GRIN1, SMARCA4
hatching (GO:0035188)	NEW	9.04	0.043	SMARCB1, SMARCA4
negative regulation of metabolic process (GO:0009892)	-	1.93	0.023	ZMYND11, NR1I3, SMARCA4, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, PPP2R1A, ARID1A, MEF2C
RNA biosynthetic process (GO:0032774)	-	1.84	0.005	ADNP, NR1I3, SMARCA4, ARID1A, CTCF, DEAF1, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, MEF2C, ARID1B
negative regulation of biosynthetic process (GO:0009890)	-	2.47	0.001	ZMYND11, NR1I3, SMARCA4, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C
negative regulation of cellular biosynthetic process (GO:0031327)	-	2.49	0.001	ZMYND11, NR1I3, CTNNB1, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, SMARCA4, MEF2C, ARID1A
regulation of cellular biosynthetic process (GO:0031326)	-	1.38	0.015	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
regulation of RNA biosynthetic process (GO:2001141)	-	1.55	0.001	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
RNA metabolic process (GO:0016070)	-	1.59	0.047	ADNP, NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PPP2R1A, PURA, KMT2C, ARID1A, ARID1B
behavior (GO:0007610)	-	3.47	0.008	ADNP, SYNGAP1, MBD5, MEF2C, SMARCB1, GATAD2B, SMARCE1, PPP2R5D, CACNG2, DYRK1A, PPP2R1A, GRIN1, GRIN2B, CTNNB1, SMARCA4
regulation of gene expression, epigenetic (GO:0040029)	-	4.58	0.01	SMARCA4, EHMT1, ARID1A, ARID1B, CTCF
embryo development (GO:0009790)	-	4.2	0.012	COL4A3BP, CTCF, MEF2C, ZBTB18, SMARCE1, EHMT1, CTNNB1, PPP2R1A, GRIN1, GRIN2B, SMARCA4
negative regulation of gene expression (GO:0010629)	-	2.48	0.0	PPP2R5D, CACNG2, GATAD2B, ARID1A, SMARCE1, NR1I3, CTCF, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, GRIN1, SMARCB1, ZBTB18, PPP2R1A, KMT2C, EHMT1, PURA, SMARCA4, DYRK1A, MEF2C
cell cycle process (GO:0022402)	-	2.75	0.0	DYRK1A, KIF1A, CTNNB1, PPP2R5D, CTCF, DYNC1H1, SMARCB1, GRIN2B, CACNG2, POGZ, SMARCE1, CHAMP1, SOX11, COL4A3BP, GRIN1, PPP2R1A, PACS1, ARID1A, MEF2C, SMARCA4
cellular macromolecule biosynthetic process (GO:0034645)	-	1.66	0.009	ADNP, NR1I3, SMARCA4, ARID1A, CTCF, DEAF1, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, EEF1A2, MEF2C, ARID1B
regulation of long-term neuronal synaptic plasticity (GO:0048169)	-	6.55	0.036	EPB41L1, GRIN2B, GRIN1, SYNGAP1
synaptic transmission, glutamatergic (GO:0035249)	NEW	6.64	0.048	GRIN2B, CACNG2, GRIN1, CTNNB1
cellular component organization or biogenesis (GO:0071840)	-	1.22	0.001	CTCF, CACNG2, GRIN1, ARID1A, SMARCE1, SYNGAP1, KAT6A, POGZ, ZMYND11, CHAMP1, CTNNB1, SMARCB1, KANSL1, COL4A3BP, DYNC1H1, EPB41L1, PPP2R1A, KMT2C, SMARCA4, EHMT1, GATAD2B, CDH15, MEF2C, ARID1B
protein-DNA complex disassembly (GO:0032986)	-	6.9	0.0	SMARCE1, ARID1A, SMARCB1, SMARCA4
negative regulation of transcription from RNA polymerase II promoter (GO:0000122)	-	3.12	0.01	ZMYND11, GRIN1, PPP2R5D, KAT6A, EPB41L1, GRIN2B, SMARCB1, CHAMP1, ZBTB18, SMARCE1, CACNG2, EHMT1, CTCF, SOX11, GATAD2B, CTNNB1, MEF2C, ARID1A, SMARCA4
negative regulation of protein metabolic process (GO:0051248)	-	2.82	0.008	NR1I3, KIF1A, GRIN1, PPP2R5D, DYNC1H1, EPB41L1, GRIN2B, PURA, SMARCE1, PACS1, CTNNB1, PPP2R1A, MEF2C, EEF1A2, SMARCB1, SMARCA4
negative regulation of macromolecule metabolic process (GO:0010605)	-	2.01	0.008	ZMYND11, NR1I3, SMARCA4, CTCF, KAT6A, PURA, SMARCE1, EHMT1, SOX11, ZBTB18, CTNNB1, PPP2R1A, ARID1A, MEF2C
regulation of secondary heart field cardioblast proliferation (GO:0003266)	NEW	7.65	0.02	MEF2C, SMARCA4, CTNNB1
regulation of cardioblast proliferation (GO:0003264)	NEW	7.53	0.02	MEF2C, SMARCA4, CTNNB1
chromatin organization (GO:0006325)	-	3.28	0.002	ZMYND11, KANSL1, DYRK1A, CTCF, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, CTNNB1, SMARCA4, KMT2C, ARID1A, ARID1B
regulation of growth (GO:0040008)	-	3.26	0.019	SYNGAP1, MBD5, CTCF, DYNC1H1, SMARCB1, CTNNB1, SETD5, SMARCE1, CACNG2, PACS1, SMARCA4, PPP2R1A, GRIN1, MEF2C, EEF1A2, GRIN2B
ATP-dependent chromatin remodeling (GO:0043044)	-	5.6	0.0	SMARCE1, ARID1A, SMARCB1, SMARCA4, GATAD2B
regulation of cellular macromolecule biosynthetic process (GO:2000112)	-	1.46	0.005	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
negative regulation of cellular macromolecule biosynthetic process (GO:2000113)	-	2.6	0.0	PPP2R5D, CACNG2, PURA, ARID1A, SMARCE1, NR1I3, CTCF, EEF1A2, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, GRIN1, DYNC1H1, EPB41L1, ZBTB18, KMT2C, EHMT1, GATAD2B, SMARCA4, DYRK1A, MEF2C
cellular component organization (GO:0016043)	-	1.24	0.001	CTCF, CACNG2, GRIN1, ARID1A, SMARCE1, SYNGAP1, KAT6A, POGZ, ZMYND11, CHAMP1, CTNNB1, SMARCB1, KANSL1, COL4A3BP, DYNC1H1, EPB41L1, PPP2R1A, KMT2C, SMARCA4, EHMT1, GATAD2B, CDH15, MEF2C, ARID1B
cerebral cortex development (GO:0021987)	NEW	5.57	0.035	GRIN1, SMARCB1, ZBTB18, SMARCA4, CTNNB1
regulation of chromatin organization (GO:1902275)	-	4.69	0.016	CTNNB1, CTCF, SETD5, SMARCE1, DYRK1A, GRIN1, SMARCA4
regulation of transcription from RNA polymerase II promoter (GO:0006357)	-	2.24	0.001	ZMYND11, NR1I3, SMARCA4, CTCF, DEAF1, SMARCB1, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, GRIN1, MEF2C, CTNNB1, ARID1A
cell cycle (GO:0007049)	-	3.14	0.001	SMARCE1, COL4A3BP, PPP2R5D, DYNC1H1, SMARCB1, PURA, ZMYND11, PACS1, DYRK1A, PPP2R1A, GRIN1, GRIN2B, EEF1A2, SMARCA4
transcription from RNA polymerase II promoter (GO:0006366)	-	3.38	0.002	KANSL1, SMARCA4, PPP2R5D, CTCF, MEF2C, SMARCB1, NR1I3, PURA, ZMYND11, KAT6A, CTNNB1, PPP2R1A, KMT2C, DEAF1
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (GO:2000311)	-	6.78	0.005	GRIN1, GRIN2B, MEF2C, CACNG2
regulation of gene expression (GO:0010468)	-	1.37	0.023	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
heterocycle biosynthetic process (GO:0018130)	-	1.7	0.034	ADNP, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, NR1I3, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, ARID1A, ARID1B
developmental process (GO:0032502)	-	1.36	0.02	PPP2R5D, EHMT1, KIRREL3, GRIN1, ARID1A, MYT1L, SYNGAP1, SMARCE1, KAT6A, SOX11, CTNNB1, GRIN2B, SMARCB1, SMARCA4, MBD5, DEAF1, ZBTB18, PURA, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
protein-DNA complex subunit organization (GO:0071824)	-	4.45	0.049	CTCF, SMARCB1, SMARCE1, KAT6A, SMARCA4, ARID1A
negative regulation of cellular metabolic process (GO:0031324)	-	2.01	0.01	ZMYND11, NR1I3, CTNNB1, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, SMARCA4, PPP2R1A, MEF2C, ARID1A
negative regulation of nucleobase-containing compound metabolic process (GO:0045934)	-	2.55	0.0	PPP2R5D, CACNG2, PURA, ARID1A, SMARCE1, NR1I3, CTCF, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, GRIN1, DYNC1H1, DEAF1, ZBTB18, KMT2C, EHMT1, GATAD2B, EPB41L1, SMARCA4, DYRK1A, MEF2C
neuron differentiation (GO:0030182)	-	4.17	0.006	GRIN1, PPP2R5D, MEF2C, SMARCB1, POGZ, CACNG2, SOX11, CTNNB1, PPP2R1A, GRIN2B, SMARCA4
regulation of nucleobase-containing compound metabolic process (GO:0019219)	-	1.43	0.017	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, SYNGAP1, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
cellular protein localization (GO:0034613)	-	3.11	0.05	GRIN1, SYNGAP1, CTCF, DYNC1H1, EEF1A2, CACNG2, CHAMP1, CTNNB1, PPP2R1A, GRIN2B, SMARCA4
regulation of biosynthetic process (GO:0009889)	-	1.37	0.017	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
negative regulation of RNA biosynthetic process (GO:1902679)	-	2.7	0.0	PPP2R5D, CACNG2, PURA, ARID1A, SMARCE1, NR1I3, CTCF, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, GRIN1, SMARCB1, ZBTB18, KMT2C, EHMT1, GATAD2B, SMARCA4, DYRK1A, MEF2C
macromolecule biosynthetic process (GO:0009059)	-	1.61	0.023	ADNP, GATAD2B, ARID1A, CTCF, DEAF1, SMARCB1, NR1I3, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, EEF1A2, MEF2C, ARID1B
negative regulation of transcription, DNA-templated (GO:0045892)	-	2.75	0.0	PPP2R5D, CACNG2, PURA, ARID1A, SMARCE1, NR1I3, CTCF, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, GRIN1, SMARCB1, ZBTB18, KMT2C, EHMT1, GATAD2B, SMARCA4, DYRK1A, MEF2C
regulation of nitrogen compound metabolic process (GO:0051171)	-	1.36	0.025	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, SYNGAP1, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
negative regulation of nitrogen compound metabolic process (GO:0051172)	-	2.47	0.001	ZMYND11, NR1I3, SMARCA4, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, ARID1A, MEF2C
intracellular steroid hormone receptor signaling pathway (GO:0030518)	-	5.47	0.034	PPP2R1A, SMARCA4, NR1I3, ARID1A, CTNNB1
nucleobase-containing compound biosynthetic process (GO:0034654)	-	1.72	0.022	ADNP, GATAD2B, CTCF, DEAF1, MEF2C, SMARCB1, NR1I3, ZBTB18, ZMYND11, KAT6A, SOX11, PURA, CTNNB1, MYT1L, SMARCA4, KMT2C, ARID1A, ARID1B
regulation of glutamate receptor signaling pathway (GO:1900449)	-	6.36	0.038	MEF2C, CACNG2, GRIN2B, GRIN1
negative regulation of neuron death (GO:1901215)	-	4.57	0.029	MEF2C, CTNNB1, GRIN1, SYNGAP1, ADNP
glial cell fate determination (GO:0007403)	NEW	9.73	0.021	SMARCA4, CTNNB1
regulation of centromeric sister chromatid cohesion (GO:0070602)	-	8.63	0.021	CTCF, CTNNB1
organelle organization (GO:0006996)	-	2.02	0.045	KANSL1, CTNNB1, KAT6A, DYNC1H1, EPB41L1, SMARCB1, CHAMP1, POGZ, SMARCE1, EHMT1, COL4A3BP, ARID1A, KMT2C, SMARCA4
heart morphogenesis (GO:0003007)	NEW	5.84	0.016	SMARCA4, MEF2C, COL4A3BP, CTNNB1, KAT6A
muscle cell differentiation (GO:0042692)	-	5.09	0.045	CDH15, SMARCB1, SMARCE1, CTNNB1, MEF2C, GRIN2B, SMARCA4
cellular nitrogen compound biosynthetic process (GO:0044271)	-	1.59	0.043	ADNP, NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, ARID1A, ARID1B
nervous system development (GO:0007399)	-	3.53	0.004	MYT1L, GRIN1, MBD5, SMARCB1, PURA, SMARCE1, PPP2R5D, DYRK1A, MEF2C, CTNNB1, SMARCA4, ARID1B
chromatin remodeling (GO:0006338)	-	4.78	0.035	SMARCB1, GATAD2B, SMARCE1, SMARCA4, ARID1A, ARID1B
aromatic compound biosynthetic process (GO:0019438)	-	1.7	0.033	ADNP, NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, ARID1A, ARID1B
single-organism behavior (GO:0044708)	-	3.79	0.044	MBD5, SYNGAP1, DYNC1H1, SMARCB1, CACNG2, CTNNB1, GRIN1, PPP2R1A, DYRK1A, MEF2C, GRIN2B, SMARCA4
negative regulation of RNA metabolic process (GO:0051253)	-	2.66	0.0	PPP2R5D, EHMT1, PURA, ARID1A, SMARCE1, NR1I3, CTCF, KAT6A, SETD5, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, GRIN1, SMARCB1, ZBTB18, KMT2C, CACNG2, GATAD2B, SMARCA4, DYRK1A, MEF2C
anatomical structure development (GO:0048856)	-	1.58	0.0	PPP2R5D, EHMT1, KIRREL3, GRIN1, ARID1A, MYT1L, SYNGAP1, SMARCE1, KAT6A, SOX11, CTNNB1, GRIN2B, DEAF1, COL4A3BP, MBD5, SMARCB1, ZBTB18, SMARCA4, PURA, DYRK1A, MEF2C, ARID1B
organism emergence from protective structure (GO:0071684)	NEW	9.04	0.043	SMARCB1, SMARCA4
blastocyst hatching (GO:0001835)	NEW	9.04	0.043	SMARCB1, SMARCA4
regulation of transcription, DNA-templated (GO:0006355)	-	1.56	0.001	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
single-organism organelle organization (GO:1902589)	-	2.68	0.001	KANSL1, CTNNB1, KAT6A, DYNC1H1, EPB41L1, SMARCB1, CHAMP1, POGZ, SMARCE1, EHMT1, COL4A3BP, KMT2C, ARID1A, SMARCA4
regulation of macromolecule biosynthetic process (GO:0010556)	-	1.43	0.008	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
transcription, DNA-templated (GO:0006351)	-	1.91	0.002	ADNP, NR1I3, SMARCA4, CTCF, DEAF1, MEF2C, SMARCB1, MYT1L, ZBTB18, ZMYND11, KAT6A, SOX11, GATAD2B, CTNNB1, PURA, KMT2C, ARID1A, ARID1B
nucleosome disassembly (GO:0006337)	-	6.9	0.0	SMARCE1, SMARCB1, ARID1A, SMARCA4
system development (GO:0048731)	-	2.92	0.0	MYT1L, MBD5, PPP2R5D, CTCF, DEAF1, SMARCA4, SMARCB1, CACNG2, PURA, SMARCE1, DYNC1H1, KAT6A, SOX11, GRIN1, PPP2R1A, DYRK1A, GRIN2B, CTNNB1, MEF2C, ARID1B
regulation of RNA metabolic process (GO:0051252)	-	1.52	0.002	CTCF, EHMT1, PURA, ARID1A, SMARCE1, ADNP, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, GRIN1, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, GATAD2B, SMARCA4, MEF2C, ARID1B
negative regulation of macromolecule biosynthetic process (GO:0010558)	-	2.53	0.001	ZMYND11, NR1I3, SMARCA4, CTCF, KAT6A, ZBTB18, SMARCE1, EHMT1, SOX11, PURA, CTNNB1, MEF2C, ARID1A
chromatin modification (GO:0016568)	-	4.06	0.0	ZMYND11, KANSL1, DYRK1A, CTCF, SMARCB1, KAT6A, GATAD2B, SMARCE1, EHMT1, CTNNB1, SMARCA4, ARID1A, KMT2C, ARID1B

GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
cell part (GO:0044464)	0.11	42	KIF1A, PPP2R5D, CACNG2, PACS1, PURA, KIRREL3, ARID1A, KMT2C, AUTS2, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, GRIN1, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, EHMT1, GATAD2B, EPB41L1, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
organelle (GO:0043226)	0.4	39	KIF1A, PPP2R5D, SMARCB1, EHMT1, PACS1, PURA, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, EPB41L1, DPP6, KANSL1, AUTS2, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, GATAD2B, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
intracellular part (GO:0044424)	0.28	38	KIF1A, PPP2R5D, EHMT1, PACS1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, CHAMP1, POGZ, ZMYND11, KAT6A, SOX11, CTNNB1, SMARCB1, KANSL1, AUTS2, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, CACNG2, PURA, EPB41L1, GRIN1, DYRK1A, MEF2C, COL4A3BP, ARID1B
intracellular organelle (GO:0043229)	0.51	37	KIF1A, PPP2R5D, SMARCB1, EHMT1, PACS1, PURA, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, EPB41L1, KANSL1, AUTS2, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
membrane-bounded organelle (GO:0043227)	0.47	36	PPP2R5D, EHMT1, PACS1, PURA, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, AUTS2, SMARCB1, DPP6, KANSL1, CTNNB1, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, GATAD2B, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
intracellular membrane-bounded organelle (GO:0043231)	0.6	33	PPP2R5D, EHMT1, PACS1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, AUTS2, SMARCB1, KANSL1, COL4A3BP, MBD5, DEAF1, MYT1L, ZBTB18, PPP2R1A, KMT2C, SMARCA4, NR1I3, PURA, GRIN1, DYRK1A, MEF2C, CTNNB1, ARID1B
intracellular organelle part (GO:0044446)	0.81	30	KIF1A, PPP2R5D, EHMT1, PACS1, GATAD2B, ARID1A, SMARCE1, NR1I3, CTCF, EEF1A2, CHAMP1, POGZ, ZMYND11, KAT6A, CTNNB1, SMARCB1, KANSL1, COL4A3BP, MBD5, DYNC1H1, DEAF1, ZBTB18, PPP2R1A, KMT2C, CACNG2, PURA, SMARCA4, DYRK1A, MEF2C, ARID1B
nucleus (GO:0005634)	1.07	30	PPP2R5D, EHMT1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, AUTS2, SMARCB1, KANSL1, CTNNB1, MBD5, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, SMARCA4, PURA, DYRK1A, MEF2C, ARID1B
organelle part (GO:0044422)	0.79	30	KIF1A, PPP2R5D, CACNG2, PACS1, GATAD2B, ARID1A, SMARCE1, NR1I3, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, CTNNB1, SMARCB1, KANSL1, COL4A3BP, MBD5, DYNC1H1, DEAF1, ZBTB18, PPP2R1A, KMT2C, EHMT1, PURA, SMARCA4, DYRK1A, MEF2C, ARID1B
macromolecular complex (GO:0032991)	1.35	26	KIF1A, PPP2R5D, CACNG2, PURA, GRIN1, ARID1A, EEF1A2, KAT6A, POGZ, SMARCE1, CHAMP1, CTNNB1, GRIN2B, DEAF1, DPP6, KANSL1, SMARCA4, DYNC1H1, SMARCB1, PPP2R1A, KMT2C, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
protein complex (GO:0043234)	1.51	24	KIF1A, PPP2R5D, CACNG2, PURA, GRIN1, ARID1A, EEF1A2, KAT6A, SMARCE1, CHAMP1, CTNNB1, GRIN2B, DEAF1, DPP6, KANSL1, SMARCA4, DYNC1H1, SMARCB1, PPP2R1A, KMT2C, GATAD2B, COL4A3BP, MEF2C, ARID1B
nuclear part (GO:0044428)	1.55	23	PPP2R5D, EHMT1, PURA, ARID1A, SMARCE1, NR1I3, CTCF, CHAMP1, POGZ, ZMYND11, KAT6A, CTNNB1, DEAF1, KANSL1, SMARCA4, SMARCB1, ZBTB18, KMT2C, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
nucleoplasm (GO:0005654)	1.89	22	PPP2R5D, EHMT1, ARID1A, SMARCE1, NR1I3, CTCF, CHAMP1, POGZ, ZMYND11, KAT6A, CTNNB1, DEAF1, KANSL1, SMARCA4, SMARCB1, ZBTB18, KMT2C, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
non-membrane-bounded organelle (GO:0043228)	1.76	21	SMARCE1, KANSL1, NR1I3, KIF1A, MBD5, SYNGAP1, KAT6A, DYNC1H1, EPB41L1, SMARCB1, EHMT1, POGZ, ZMYND11, CHAMP1, CTCF, ZBTB18, CTNNB1, PPP2R1A, GRIN1, DEAF1, SMARCA4
intracellular non-membrane-bounded organelle (GO:0043232)	1.76	21	SMARCE1, KANSL1, NR1I3, KIF1A, MBD5, SYNGAP1, KAT6A, DYNC1H1, DEAF1, SMARCB1, CHAMP1, ZBTB18, ZMYND11, EHMT1, CTCF, POGZ, CTNNB1, PPP2R1A, GRIN1, EPB41L1, SMARCA4
cytoplasm (GO:0005737)	1.01	19	NR1I3, KIF1A, CTNNB1, SYNGAP1, DEAF1, EPB41L1, ADNP, PURA, DYNC1H1, CHAMP1, PPP2R5D, POGZ, COL4A3BP, GRIN1, PPP2R1A, SOX11, MEF2C, EEF1A2, ARID1B
neuron part (GO:0097458)	2.64	15	ADNP, KIF1A, GRIN1, SYNGAP1, SMARCB1, PURA, SMARCE1, DPP6, CTNNB1, KIRREL3, SMARCA4, ARID1A, EEF1A2, GRIN2B, ARID1B
membrane (GO:0016020)	0.68	14	COL4A3BP, SYNGAP1, DYNC1H1, EPB41L1, ZMYND11, KIRREL3, CACNG2, CDH15, PPP2R1A, GRIN1, GRIN2B, CTNNB1, SMARCA4, DPP6
cytoplasmic part (GO:0044444)	0.82	14	NR1I3, KIF1A, CTNNB1, SYNGAP1, DYNC1H1, EPB41L1, KAT6A, PPP2R5D, CACNG2, PACS1, COL4A3BP, PPP2R1A, GRIN1, EEF1A2
chromosomal part (GO:0044427)	3.18	14	KANSL1, GATAD2B, MBD5, CTCF, SMARCB1, KAT6A, PURA, SMARCE1, CHAMP1, POGZ, CTNNB1, PPP2R1A, ARID1A, SMARCA4
membrane part (GO:0044425)	0.95	12	COL4A3BP, SYNGAP1, EPB41L1, ZMYND11, CACNG2, CDH15, KIRREL3, GRIN1, GRIN2B, CTNNB1, EEF1A2, DPP6
chromosome (GO:0005694)	3.78	11	ZMYND11, KANSL1, CTCF, MBD5, SMARCB1, CHAMP1, POGZ, SMARCE1, EHMT1, ZBTB18, PPP2R1A
cytosol (GO:0005829)	1.68	9	NR1I3, CTNNB1, SYNGAP1, DYNC1H1, EPB41L1, PPP2R5D, PACS1, COL4A3BP, PPP2R1A
extracellular region part (GO:0044421)	1.57	9	ADNP, CDH15, MBD5, DYNC1H1, ZBTB18, CTNNB1, PPP2R1A, SMARCA4, DPP6
cytoskeleton (GO:0005856)	2.55	8	NR1I3, KIF1A, DYNC1H1, EPB41L1, ZBTB18, CHAMP1, CTNNB1, PPP2R1A
vesicle (GO:0031982)	1.64	8	CTNNB1, MBD5, DYNC1H1, PACS1, CDH15, PPP2R1A, GRIN1, DPP6
membrane-bounded vesicle (GO:0031988)	1.71	8	CDH15, MBD5, DYNC1H1, PACS1, CTNNB1, PPP2R1A, GRIN1, DPP6
nuclear chromosome part (GO:0044454)	3.67	8	GATAD2B, SMARCB1, PURA, SMARCE1, POGZ, CTNNB1, ARID1A, SMARCA4
plasma membrane (GO:0005886)	1.39	8	CDH15, EPB41L1, CACNG2, CTNNB1, KIRREL3, GRIN1, GRIN2B, DPP6
intrinsic component of membrane (GO:0031224)	1.13	8	GRIN1, SYNGAP1, ZMYND11, CACNG2, CDH15, KIRREL3, GRIN2B, DPP6
catalytic complex (GO:1902494)	2.9	7	KANSL1, PPP2R5D, DYNC1H1, GATAD2B, KAT6A, PPP2R1A, KMT2C
integral component of membrane (GO:0016021)	1.14	7	GRIN1, ZMYND11, CACNG2, CDH15, KIRREL3, GRIN2B, DPP6
nuclear chromatin (GO:0000790)	4.42	7	SMARCA4, SMARCB1, GATAD2B, SMARCE1, POGZ, CTNNB1, ARID1A
chromatin (GO:0000785)	3.99	7	SMARCA4, SMARCB1, GATAD2B, SMARCE1, POGZ, CTNNB1, ARID1A
cell projection (GO:0042995)	2.47	7	ADNP, GRIN1, DYNC1H1, PURA, CTNNB1, KIRREL3, GRIN2B
plasma membrane part (GO:0044459)	1.95	7	CTNNB1, SYNGAP1, CACNG2, CDH15, GRIN1, GRIN2B, DPP6
SWI/SNF superfamily-type complex (GO:0070603)	5.5	6	SMARCB1, GATAD2B, SMARCE1, SMARCA4, ARID1A, ARID1B
extracellular exosome (GO:0070062)	1.89	6	CDH15, MBD5, DYNC1H1, CTNNB1, PPP2R1A, DPP6
nucleoplasm part (GO:0044451)	3.22	6	KANSL1, GATAD2B, KAT6A, DYRK1A, MEF2C, KMT2C
neuron projection (GO:0043005)	3.12	6	ADNP, GRIN1, PURA, CTNNB1, KIRREL3, GRIN2B
extracellular organelle (GO:0043230)	1.89	6	CDH15, MBD5, DYNC1H1, CTNNB1, PPP2R1A, DPP6
extracellular vesicle (GO:1903561)	1.89	6	CDH15, MBD5, DYNC1H1, CTNNB1, PPP2R1A, DPP6
chromosomal region (GO:0098687)	4.19	6	KANSL1, CTCF, MBD5, PURA, CHAMP1, PPP2R1A
nucleolus (GO:0005730)	3.06	5	DEAF1, SMARCB1, KAT6A, SMARCA4, CTCF
cell projection part (GO:0044463)	2.97	5	KIRREL3, KIF1A, GRIN1, CTNNB1, SYNGAP1
cell body (GO:0044297)	3.74	5	ADNP, EEF1A2, GRIN1, PURA, DPP6
plasma membrane protein complex (GO:0098797)	3.55	5	GRIN1, GRIN2B, CACNG2, CTNNB1, DPP6
membrane protein complex (GO:0098796)	2.84	5	GRIN2B, CACNG2, GRIN1, CTNNB1, DPP6
nBAF complex (GO:0071565)	7.16	5	SMARCE1, ARID1A, ARID1B, SMARCB1, SMARCA4
SWI/SNF complex (GO:0016514)	7.09	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, ARID1B
BAF-type complex (GO:0090544)	6.67	5	SMARCE1, ARID1A, SMARCB1, SMARCA4, ARID1B
neuronal cell body (GO:0043025)	3.9	5	ADNP, EEF1A2, PURA, GRIN1, DPP6
plasma membrane region (GO:0098590)	2.97	4	CDH15, GRIN2B, GRIN1, CTNNB1
nuclear body (GO:0016604)	3.94	4	MEF2C, GATAD2B, KAT6A, DYRK1A
transmembrane transporter complex (GO:1902495)	4.06	4	GRIN2B, CACNG2, GRIN1, DPP6
transporter complex (GO:1990351)	4.04	4	GRIN2B, CACNG2, GRIN1, DPP6
dendrite (GO:0030425)	3.92	4	KIRREL3, ADNP, GRIN1, PURA
cytoskeletal part (GO:0044430)	2.49	4	DYNC1H1, CHAMP1, KIF1A, CTNNB1
ion channel complex (GO:0034702)	4.18	4	GRIN2B, CACNG2, GRIN1, DPP6
npBAF complex (GO:0071564)	7.32	4	SMARCE1, SMARCB1, ARID1A, SMARCA4
synapse part (GO:0044456)	3.42	4	MEF2C, GRIN2B, GRIN1, SYNGAP1
chromosome, centromeric region (GO:0000775)	4.85	4	PPP2R1A, KANSL1, CHAMP1, CTCF
cell junction (GO:0030054)	2.75	4	EPB41L1, GRIN2B, GRIN1, CTNNB1
synapse (GO:0045202)	3.58	4	CDH15, GRIN2B, GRIN1, CTNNB1
nuclear speck (GO:0016607)	4.52	3	MEF2C, DYRK1A, GATAD2B
Golgi apparatus (GO:0005794)	2.7	3	KAT6A, PACS1, COL4A3BP
receptor complex (GO:0043235)	4.01	3	GRIN2B, CACNG2, GRIN1
dendritic shaft (GO:0043198)	6.16	3	KIRREL3, CTNNB1, SYNGAP1
cell surface (GO:0009986)	3.44	3	GRIN2B, DPP6, GRIN1
ionotropic glutamate receptor complex (GO:0008328)	5.97	3	GRIN2B, CACNG2, GRIN1
plasma membrane receptor complex (GO:0098802)	4.63	3	GRIN2B, CACNG2, GRIN1
(GO:0098878)	5.97	3	GRIN2B, CACNG2, GRIN1
extracellular region (GO:0005576)	2.18	3	KIRREL3, DEAF1, GRIN1
transferase complex (GO:1990234)	3.32	3	KMT2C, KANSL1, KAT6A
nuclear chromosome (GO:0000228)	5.55	3	SMARCE1, SMARCB1, ZBTB18
intrinsic component of plasma membrane (GO:0031226)	2.53	3	GRIN2B, GRIN1, SYNGAP1
perinuclear region of cytoplasm (GO:0048471)	3.35	3	PACS1, COL4A3BP, CTNNB1
protein acetyltransferase complex (GO:0031248)	5.21	2	KANSL1, KAT6A
supramolecular fiber (GO:0099512)	3.31	2	DYNC1H1, KIF1A
polymeric cytoskeletal fiber (GO:0099513)	3.31	2	DYNC1H1, KIF1A
phosphatase complex (GO:1903293)	5.93	2	PPP2R1A, PPP2R5D
postsynaptic specialization (GO:0099572)	4.77	2	GRIN1, SYNGAP1
axon (GO:0030424)	4.15	2	KIRREL3, ADNP
microtubule cytoskeleton (GO:0015630)	4.78	2	PPP2R1A, ZBTB18
cation channel complex (GO:0034703)	4.69	2	CACNG2, DPP6
integral component of plasma membrane (GO:0005887)	2.57	2	GRIN2B, GRIN1
microtubule (GO:0005874)	3.81	2	DYNC1H1, KIF1A
microtubule associated complex (GO:0005875)	4.79	2	DYNC1H1, KIF1A
methyltransferase complex (GO:0034708)	5.3	2	KMT2C, KANSL1
endoplasmic reticulum (GO:0005783)	2.56	2	COL4A3BP, GRIN1
synaptic membrane (GO:0097060)	4.22	2	GRIN2B, GRIN1
extracellular space (GO:0005615)	2.63	2	ADNP, SMARCA4
histone acetyltransferase complex (GO:0000123)	5.32	2	KAT6A, KANSL1
cytoplasmic, membrane-bounded vesicle (GO:0016023)	3.12	2	PACS1, GRIN1
cytoplasmic vesicle (GO:0031410)	2.87	2	PACS1, GRIN1
mitochondrion (GO:0005739)	2.42	2	PPP2R1A, COL4A3BP
microtubule organizing center (GO:0005815)	3.42	2	DYNC1H1, CTNNB1
centrosome (GO:0005813)	3.75	2	DYNC1H1, CTNNB1
acetyltransferase complex (GO:1902493)	5.21	2	KAT6A, KANSL1
protein serine/threonine phosphatase complex (GO:0008287)	5.93	2	PPP2R1A, PPP2R5D
transcriptional repressor complex (GO:0017053)	5.37	2	SMARCE1, GATAD2B
cytoplasmic region (GO:0099568)	4.51	2	KIF1A, CTNNB1
postsynaptic membrane (GO:0045211)	4.47	2	GRIN2B, GRIN1
postsynaptic density (GO:0014069)	4.77	2	GRIN1, SYNGAP1
intracellular vesicle (GO:0097708)	2.86	2	PACS1, GRIN1
cell-cell junction (GO:0005911)	3.85	2	EPB41L1, CTNNB1
kinetochore (GO:0000776)	5.05	2	KANSL1, CHAMP1
condensed chromosome kinetochore (GO:0000777)	5.31	2	KANSL1, CHAMP1
protein phosphatase type 2A complex (GO:0000159)	6.81	2	PPP2R1A, PPP2R5D
protein-DNA complex (GO:0032993)	5.03	2	KAT6A, CTNNB1
condensed chromosome (GO:0000793)	5.64	2	CHAMP1, CTCF
histone methyltransferase complex (GO:0035097)	5.54	2	KMT2C, KANSL1
postsynapse (GO:0098794)	4.87	2	MEF2C, GRIN1
transcription factor complex (GO:0005667)	4.1	2	DEAF1, CTNNB1
axon part (GO:0033267)	4.4	2	KIF1A, GRIN1
NMDA selective glutamate receptor complex (GO:0017146)	7.4	2	GRIN2B, GRIN1

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
intracellular organelle (GO:0043229)	-	0.51	0.002	PPP2R5D, SMARCB1, EHMT1, PACS1, PURA, GRIN1, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, EPB41L1, KANSL1, SMARCA4, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, NR1I3, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
chromatin (GO:0000785)	-	3.99	0.006	SMARCA4, PPP2R5D, SMARCB1, POGZ, SMARCE1, KAT6A, GATAD2B, CTNNB1, MEF2C, ARID1A
membrane-bounded organelle (GO:0043227)	-	0.47	0.001	PPP2R5D, EHMT1, PACS1, PURA, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, DPP6, KANSL1, GRIN1, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, GATAD2B, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
organelle (GO:0043226)	-	0.4	0.004	PPP2R5D, SMARCB1, EHMT1, PACS1, PURA, ARID1A, KMT2C, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, EPB41L1, DPP6, KANSL1, GRIN1, MBD5, DYNC1H1, DEAF1, MYT1L, ZBTB18, PPP2R1A, SETBP1, SMARCA4, NR1I3, GATAD2B, CDH15, DYRK1A, MEF2C, COL4A3BP, ARID1B
SWI/SNF superfamily-type complex (GO:0070603)	-	5.5	0.001	SMARCE1, ARID1A, ARID1B, SMARCB1, SMARCA4
nuclear chromosome part (GO:0044454)	-	3.67	0.0	GATAD2B, PPP2R5D, CTCF, SMARCB1, PURA, SMARCE1, KAT6A, POGZ, CTNNB1, MEF2C, ARID1A, SMARCA4
nucleus (GO:0005634)	-	1.07	0.0	PPP2R5D, EHMT1, GATAD2B, ARID1A, SETBP1, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, SMARCB1, KANSL1, SMARCA4, MBD5, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, PURA, DYRK1A, MEF2C, COL4A3BP, ARID1B
nucleoplasm (GO:0005654)	-	1.89	0.018	KANSL1, NR1I3, DYRK1A, PPP2R5D, KAT6A, EPB41L1, SMARCB1, CHAMP1, PURA, SMARCE1, EHMT1, CTCF, CTNNB1, PPP2R1A, GRIN1, MEF2C, KMT2C, EEF1A2, SMARCA4
neuron part (GO:0097458)	-	2.64	0.001	ADNP, KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, EEF1A2, SMARCB1, CACNG2, PURA, SMARCE1, PPP2R5D, CTNNB1, PPP2R1A, GRIN1, GRIN2B, EPB41L1, SMARCA4, ARID1A
nucleoplasm part (GO:0044451)	-	3.22	0.035	KANSL1, DYRK1A, CTCF, SMARCB1, GATAD2B, SMARCE1, KAT6A, CTNNB1, PPP2R1A, MEF2C, KMT2C, SMARCA4
neuron projection (GO:0043005)	-	3.12	0.019	KIF1A, COL4A3BP, SYNGAP1, DYNC1H1, EPB41L1, PURA, SMARCE1, CACNG2, CTNNB1, PPP2R1A, GRIN1, GRIN2B, SMARCB1, SMARCA4
SWI/SNF complex (GO:0016514)	-	7.09	0.0	SMARCE1, ARID1A, SMARCB1, SMARCA4, ARID1B
nuclear part (GO:0044428)	-	1.55	0.0	GATAD2B, PPP2R5D, EHMT1, SETD5, GRIN1, ARID1A, SETBP1, NR1I3, CTCF, EEF1A2, KAT6A, POGZ, SMARCE1, CHAMP1, CTNNB1, SMARCB1, KANSL1, SMARCA4, DYNC1H1, EPB41L1, ZBTB18, PPP2R1A, KMT2C, CACNG2, PURA, COL4A3BP, DYRK1A, MEF2C, ARID1B
neuronal cell body (GO:0043025)	-	3.9	0.011	KIF1A, SMARCA4, SYNGAP1, EEF1A2, PURA, CACNG2, CTNNB1, PPP2R1A, GRIN1, GRIN2B
ionotropic glutamate receptor complex (GO:0008328)	-	5.97	0.031	GRIN2B, CACNG2, GRIN1
chromosome (GO:0005694)	-	3.78	0.0	ZMYND11, SMARCA4, CTCF, SMARCB1, CHAMP1, ZBTB18, SMARCE1, EHMT1, CTNNB1
cell body (GO:0044297)	-	3.74	0.037	KIF1A, SMARCA4, SYNGAP1, EEF1A2, PURA, CACNG2, CTNNB1, PPP2R1A, GRIN1, GRIN2B
nuclear chromatin (GO:0000790)	-	4.42	0.0	SMARCA4, SMARCB1, POGZ, SMARCE1, KAT6A, GATAD2B, CTNNB1, MEF2C, ARID1A
transferase complex (GO:1990234)	-	3.32	0.027	KANSL1, GRIN1, DYNC1H1, SMARCB1, KAT6A, SMARCE1, CHAMP1, CTNNB1, PPP2R1A, KMT2C, GRIN2B
BAF-type complex (GO:0090544)	-	6.67	0.0	SMARCE1, ARID1A, SMARCB1, SMARCA4, ARID1B
protein complex (GO:0043234)	-	1.51	0.001	KIF1A, PPP2R5D, EHMT1, PACS1, GATAD2B, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, CHAMP1, SETD5, SMARCE1, KAT6A, CTNNB1, GRIN2B, SMARCB1, KANSL1, COL4A3BP, DYNC1H1, DEAF1, NR1I3, PPP2R1A, KMT2C, CACNG2, PURA, EPB41L1, SMARCA4, DYRK1A, MEF2C, ARID1B
macromolecular complex (GO:0032991)	-	1.35	0.0	KIF1A, PPP2R5D, EHMT1, PACS1, SETD5, GRIN1, ARID1A, ADNP, CTCF, SYNGAP1, EEF1A2, KAT6A, POGZ, SMARCE1, CHAMP1, CTNNB1, PURA, GRIN2B, SMARCB1, KANSL1, COL4A3BP, DYNC1H1, DEAF1, NR1I3, PPP2R1A, KMT2C, CACNG2, GATAD2B, EPB41L1, SMARCA4, DYRK1A, MEF2C, ARID1B
intracellular membrane-bounded organelle (GO:0043231)	-	0.6	0.002	PPP2R5D, EHMT1, PACS1, GATAD2B, GRIN1, ARID1A, SETBP1, SMARCE1, ADNP, CTCF, EEF1A2, KAT6A, POGZ, ZMYND11, CHAMP1, SOX11, CTNNB1, GRIN2B, SMARCB1, KANSL1, COL4A3BP, MBD5, DEAF1, NR1I3, ZBTB18, MYT1L, PPP2R1A, KMT2C, PURA, SMARCA4, DYRK1A, MEF2C, ARID1B
protein-DNA complex (GO:0032993)	-	5.03	0.036	CTNNB1, CTCF, SMARCB1, KAT6A, SMARCA4, PPP2R1A
dendritic shaft (GO:0043198)	-	6.16	0.022	GRIN2B, CTNNB1, CACNG2, SYNGAP1
intracellular organelle part (GO:0044446)	-	0.81	0.003	KIF1A, PPP2R5D, EHMT1, PACS1, PURA, GRIN1, ARID1A, NR1I3, CTCF, KAT6A, POGZ, SMARCE1, CHAMP1, CTNNB1, GRIN2B, KANSL1, SMARCA4, MBD5, DYNC1H1, SMARCB1, ZBTB18, PPP2R1A, KMT2C, CACNG2, GATAD2B, COL4A3BP, DYRK1A, MEF2C, ARID1B
nBAF complex (GO:0071565)	-	7.16	0.0	SMARCE1, ARID1A, SMARCB1, SMARCA4
npBAF complex (GO:0071564)	-	7.32	0.0	SMARCE1, SMARCB1, ARID1A, SMARCA4
N-methyl-D-aspartate selective glutamate receptor complex (GO:0017146)	-	7.4	0.041	GRIN2B, GRIN1
chromosomal part (GO:0044427)	-	3.18	0.0	PPP2R5D, MBD5, CTCF, DYNC1H1, MEF2C, SMARCB1, KAT6A, GATAD2B, SMARCE1, CHAMP1, PURA, CTNNB1, POGZ, PPP2R1A, ARID1A, SMARCA4
organelle part (GO:0044422)	-	0.79	0.006	KIF1A, PPP2R5D, CACNG2, PACS1, GATAD2B, GRIN1, ARID1A, NR1I3, CTCF, KAT6A, POGZ, SMARCE1, CHAMP1, CTNNB1, GRIN2B, KANSL1, SMARCA4, MBD5, DYNC1H1, SMARCB1, ZBTB18, PPP2R1A, KMT2C, EHMT1, PURA, COL4A3BP, DYRK1A, MEF2C, ARID1B