Gene table of ODC1 : ornithine decarboxylase 1

Gene-disease associations table

Disease IDDisease nameSource of annotation with ODC1OMIM linkNumber of associated genesgenes
114500COLORECTAL CANCEROMIM link to OMIM 30TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B

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Annotation of the gene ODC1

Associated genes in ENSEMBL
Associated proteins - SwissProt Accession ID
Associated PDB IDs
Cytogenetic Band
Tandem repeats annotation
Transcription regulation as annotated in TRRUST

It is regulated by the following TF:

Associated KEGG pathways
KEGG pathwayKEGG IDKEGG IC
Metabolic pathwayshsa011002.49
Glutathione metabolismhsa004806.96
Arginine and proline metabolismhsa003306.84
Associated REACTOME pathways
REACTOME pathwayREACTOME IDREACTOME IC
Metabolism of amino acids and derivativesR-HSA-712915.4
Regulation of ornithine decarboxylase (ODC)R-HSA-3505627.34
MetabolismR-HSA-14307282.34
Metabolism of polyaminesR-HSA-3512029.08
Associated GO terms for Molecular function
GO termGO IDGO IC
lyase activityGO:00168294.53
carbon-carbon lyase activityGO:00168305.81
carboxy-lyase activityGO:00168316.15
catalytic activityGO:00038241.05
bindingGO:00054880.18
protein bindingGO:00055150.46
ornithine decarboxylase activityGO:00045869.74
protein dimerization activityGO:00469832.72
identical protein bindingGO:00428022.63
protein homodimerization activityGO:00428033.16