Disease ID | Disease name | Source of annotation with ODC1 | OMIM link | Number of associated genes | genes |
---|---|---|---|---|---|
114500 | COLORECTAL CANCER | OMIM | link to OMIM | 30 | TLR4, RAD54B, PTPRJ, TP53, EP300, PTPN12, ODC1, FLCN, TLR2, BAX, PLA2G2A, AURKA, NRAS, APC, MCC, TRIM28, MLH3, AKT1, MT-CO1, AXIN2, CTNNB1, PDGFRL, PIK3CA, KAT5, DCC, BRAF, CCND1, FGFR3, DLC1, BUB1B |
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KEGG pathway | KEGG ID | KEGG IC |
---|---|---|
Metabolic pathways | hsa01100 | 2.49 |
Glutathione metabolism | hsa00480 | 6.96 |
Arginine and proline metabolism | hsa00330 | 6.84 |
REACTOME pathway | REACTOME ID | REACTOME IC |
---|---|---|
Metabolism of amino acids and derivatives | R-HSA-71291 | 5.4 |
Regulation of ornithine decarboxylase (ODC) | R-HSA-350562 | 7.34 |
Metabolism | R-HSA-1430728 | 2.34 |
Metabolism of polyamines | R-HSA-351202 | 9.08 |
GO term | GO ID | GO IC |
---|---|---|
lyase activity | GO:0016829 | 4.53 |
carbon-carbon lyase activity | GO:0016830 | 5.81 |
carboxy-lyase activity | GO:0016831 | 6.15 |
catalytic activity | GO:0003824 | 1.05 |
binding | GO:0005488 | 0.18 |
protein binding | GO:0005515 | 0.46 |
ornithine decarboxylase activity | GO:0004586 | 9.74 |
protein dimerization activity | GO:0046983 | 2.72 |
identical protein binding | GO:0042802 | 2.63 |
protein homodimerization activity | GO:0042803 | 3.16 |