Gene | Associated with PILOMATRIXOMA in | Link to HGNC | Cytogenetic band | Number of associated diseases | Associated diseases |
---|---|---|---|---|---|
CTNNB1 | ClinVar, OMIM, HUMSAVAR | HGNC link | 3p22.1 | 6 | 114550, 155255, 167000, PS156200, 114500, 132600 |
MUTYH | OMIM | HGNC link | 1p34.1 | 3 | 132600, 613659, PS175100 |
Download the disease annotation in CSV format
TF | associated to this disease | # regulated genes | Regulated genes | # regulated genes associated with this disease | Regulated genes associated with this disease |
---|---|---|---|---|---|
CTNNB1 | YES | 20 | PTGS2, BIRC5, PPARD, CHGA, TCF7, CLDN2, CCND1, GLCE, CD44, GLI2, NRCAM, RB1, MMP14, JUN, SPP1, VIM, MYC, PLD1, MMP7, STARD7 | 0 |
regulated gene | associated to this disease | # TFs | TFs | # TFs associated with this disease | TFs associated with this disease |
---|---|---|---|---|---|
CTNNB1 | YES | 8 | AR, NKX2-5, LEF1, TP53, NELFCD, SOX6, ESR1, SIRT1 | 0 |
Gene1 | Gene2 | Direct Interaction | Number of shared interactors | Shared genes in interaction |
---|---|---|---|---|
CTNNB1 | MUTYH | No | 1 | HUWE1 |
Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)
Gene1 | Gene2 | Direct Interaction | Interaction mode | Number of shared interactors | Shared genes in interaction |
---|---|---|---|---|---|
CTNNB1 | MUTYH | No | - | 1 | UBC |
Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)
GO | IC | Number of genes with the same GO | Genes |
---|---|---|---|
protein binding (GO:0005515) | 0.46 | 2 | MUTYH, CTNNB1 |
organic cyclic compound binding (GO:0097159) | 1.05 | 2 | MUTYH, CTNNB1 |
macromolecular complex binding (GO:0044877) | 2.61 | 2 | MUTYH, CTNNB1 |
binding (GO:0005488) | 0.18 | 2 | MUTYH, CTNNB1 |
nucleic acid binding (GO:0003676) | 1.44 | 2 | MUTYH, CTNNB1 |
DNA binding (GO:0003677) | 1.92 | 2 | MUTYH, CTNNB1 |
protein complex binding (GO:0032403) | 3.09 | 2 | MUTYH, CTNNB1 |
heterocyclic compound binding (GO:1901363) | 1.06 | 2 | MUTYH, CTNNB1 |
GO | IC | Number of genes with the same GO | Genes |
---|---|---|---|
intracellular organelle part (GO:0044446) | 0.81 | 2 | MUTYH, CTNNB1 |
intracellular membrane-bounded organelle (GO:0043231) | 0.6 | 2 | MUTYH, CTNNB1 |
nucleus (GO:0005634) | 1.07 | 2 | MUTYH, CTNNB1 |
cell part (GO:0044464) | 0.11 | 2 | MUTYH, CTNNB1 |
cytoplasmic part (GO:0044444) | 0.82 | 2 | MUTYH, CTNNB1 |
nucleoplasm (GO:0005654) | 1.89 | 2 | MUTYH, CTNNB1 |
intracellular organelle (GO:0043229) | 0.51 | 2 | MUTYH, CTNNB1 |
nuclear part (GO:0044428) | 1.55 | 2 | MUTYH, CTNNB1 |
intracellular part (GO:0044424) | 0.28 | 2 | MUTYH, CTNNB1 |
membrane-bounded organelle (GO:0043227) | 0.47 | 2 | MUTYH, CTNNB1 |
organelle (GO:0043226) | 0.4 | 2 | MUTYH, CTNNB1 |
organelle part (GO:0044422) | 0.79 | 2 | MUTYH, CTNNB1 |