negative regulation of metabolic process (GO:0009892) | 1.93 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of primary metabolic process (GO:0080090) | 1.08 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of metabolic process (GO:0019222) | 1.02 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of cellular biosynthetic process (GO:0031326) | 1.38 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
negative regulation of cellular metabolic process (GO:0031324) | 2.01 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of cellular metabolic process (GO:0031323) | 1.07 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of biological process (GO:0050789) | 0.45 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
single-organism process (GO:0044699) | 0.48 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
negative regulation of macromolecule metabolic process (GO:0010605) | 2.01 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of cellular macromolecule biosynthetic process (GO:2000112) | 1.46 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
biological regulation (GO:0065007) | 0.39 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
negative regulation of biological process (GO:0048519) | 1.33 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of gene expression (GO:0010468) | 1.37 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of macromolecule metabolic process (GO:0060255) | 1.08 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
cellular process (GO:0009987) | 0.26 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of biosynthetic process (GO:0009889) | 1.37 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of cellular process (GO:0050794) | 0.5 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
single-organism cellular process (GO:0044763) | 0.65 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of nitrogen compound metabolic process (GO:0051171) | 1.36 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
negative regulation of nitrogen compound metabolic process (GO:0051172) | 2.47 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
regulation of macromolecule biosynthetic process (GO:0010556) | 1.43 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
negative regulation of cellular process (GO:0048523) | 1.41 | 6 | VHL, HNF1A, OGG1, HNF1B, RNF139, FLCN |
positive regulation of metabolic process (GO:0009893) | 1.74 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
negative regulation of biosynthetic process (GO:0009890) | 2.47 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
negative regulation of cellular biosynthetic process (GO:0031327) | 2.49 | 5 | VHL, RNF139, HNF1A, HNF1B, FLCN |
positive regulation of cellular metabolic process (GO:0031325) | 1.81 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
negative regulation of gene expression (GO:0010629) | 2.48 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
positive regulation of macromolecule metabolic process (GO:0010604) | 1.81 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
cellular macromolecule metabolic process (GO:0044260) | 0.93 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
negative regulation of cellular macromolecule biosynthetic process (GO:2000113) | 2.6 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
organic substance metabolic process (GO:0071704) | 0.63 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
positive regulation of biological process (GO:0048518) | 1.2 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
regulation of biological quality (GO:0065008) | 1.68 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
developmental process (GO:0032502) | 1.36 | 5 | VHL, HNF1B, HNF1A, FLCN, OGG1 |
negative regulation of nucleobase-containing compound metabolic process (GO:0045934) | 2.55 | 5 | VHL, HNF1B, HNF1A, OGG1, FLCN |
regulation of nucleobase-containing compound metabolic process (GO:0019219) | 1.43 | 5 | VHL, HNF1B, HNF1A, OGG1, FLCN |
regulation of nucleic acid-templated transcription (GO:1903506) | 1.55 | 5 | VHL, HNF1B, HNF1A, OGG1, FLCN |
single-organism developmental process (GO:0044767) | 1.49 | 5 | VHL, HNF1B, HNF1A, FLCN, OGG1 |
metabolic process (GO:0008152) | 0.58 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
regulation of RNA biosynthetic process (GO:2001141) | 1.55 | 5 | VHL, HNF1B, HNF1A, FLCN, OGG1 |
primary metabolic process (GO:0044238) | 0.69 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
response to stimulus (GO:0050896) | 1.22 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
regulation of RNA metabolic process (GO:0051252) | 1.52 | 5 | VHL, HNF1B, HNF1A, FLCN, OGG1 |
cellular metabolic process (GO:0044237) | 0.69 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
macromolecule metabolic process (GO:0043170) | 0.83 | 5 | VHL, HNF1B, HNF1A, RNF139, OGG1 |
regulation of transcription, DNA-templated (GO:0006355) | 1.56 | 5 | VHL, HNF1B, HNF1A, FLCN, OGG1 |
negative regulation of macromolecule biosynthetic process (GO:0010558) | 2.53 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
positive regulation of cellular process (GO:0048522) | 1.3 | 5 | VHL, HNF1B, HNF1A, RNF139, FLCN |
positive regulation of biosynthetic process (GO:0009891) | 2.29 | 4 | VHL, HNF1B, HNF1A, FLCN |
response to stress (GO:0006950) | 1.8 | 4 | VHL, RNF139, HNF1A, OGG1 |
regulation of response to stimulus (GO:0048583) | 1.54 | 4 | HNF1B, HNF1A, OGG1, FLCN |
positive regulation of gene expression (GO:0010628) | 2.35 | 4 | VHL, HNF1B, HNF1A, FLCN |
regulation of cell death (GO:0010941) | 2.43 | 4 | VHL, HNF1B, FLCN, OGG1 |
regulation of apoptotic process (GO:0042981) | 2.5 | 4 | VHL, HNF1B, FLCN, OGG1 |
cellular component organization or biogenesis (GO:0071840) | 1.22 | 4 | VHL, HNF1B, HNF1A, FLCN |
negative regulation of transcription from RNA polymerase II promoter (GO:0000122) | 3.12 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of cellular biosynthetic process (GO:0031328) | 2.3 | 4 | VHL, HNF1B, HNF1A, FLCN |
cellular component organization (GO:0016043) | 1.24 | 4 | VHL, HNF1B, HNF1A, FLCN |
regulation of programmed cell death (GO:0043067) | 2.49 | 4 | VHL, HNF1B, OGG1, FLCN |
positive regulation of nucleic acid-templated transcription (GO:1903508) | 2.56 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of nucleobase-containing compound metabolic process (GO:0045935) | 2.35 | 4 | VHL, HNF1B, HNF1A, FLCN |
negative regulation of nucleic acid-templated transcription (GO:1903507) | 2.71 | 4 | VHL, HNF1B, HNF1A, FLCN |
negative regulation of RNA biosynthetic process (GO:1902679) | 2.7 | 4 | VHL, HNF1B, HNF1A, FLCN |
macromolecule modification (GO:0043412) | 1.73 | 4 | VHL, RNF139, HNF1A, OGG1 |
negative regulation of transcription, DNA-templated (GO:0045892) | 2.75 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of transcription, DNA-templated (GO:0045893) | 2.56 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of nitrogen compound metabolic process (GO:0051173) | 2.29 | 4 | VHL, HNF1B, HNF1A, FLCN |
response to chemical (GO:0042221) | 1.98 | 4 | HNF1B, HNF1A, RNF139, OGG1 |
regulation of localization (GO:0032879) | 1.94 | 4 | RNF139, HNF1A, FLCN, OGG1 |
response to organic substance (GO:0010033) | 2.2 | 4 | HNF1B, HNF1A, RNF139, OGG1 |
negative regulation of RNA metabolic process (GO:0051253) | 2.66 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of RNA metabolic process (GO:0051254) | 2.51 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of RNA biosynthetic process (GO:1902680) | 2.54 | 4 | VHL, HNF1B, HNF1A, FLCN |
positive regulation of macromolecule biosynthetic process (GO:0010557) | 2.39 | 4 | VHL, HNF1B, HNF1A, FLCN |
regulation of transcription from RNA polymerase II promoter (GO:0006357) | 2.24 | 4 | VHL, HNF1B, HNF1A, FLCN |
regulation of cellular localization (GO:0060341) | 3.03 | 3 | RNF139, OGG1, FLCN |
regulation of transport (GO:0051049) | 2.24 | 3 | RNF139, HNF1A, OGG1 |
regulation of cellular component organization (GO:0051128) | 2.01 | 3 | HNF1B, HNF1A, FLCN |
nucleic acid metabolic process (GO:0090304) | 1.46 | 3 | HNF1B, HNF1A, OGG1 |
cellular nitrogen compound metabolic process (GO:0034641) | 1.22 | 3 | HNF1B, HNF1A, OGG1 |
nitrogen compound metabolic process (GO:0006807) | 1.13 | 3 | HNF1B, HNF1A, OGG1 |
signal transduction (GO:0007165) | 1.28 | 3 | HNF1B, HNF1A, FLCN |
regulation of signaling (GO:0023051) | 1.72 | 3 | HNF1B, HNF1A, FLCN |
anatomical structure morphogenesis (GO:0009653) | 2.53 | 3 | VHL, HNF1B, HNF1A |
organic cyclic compound metabolic process (GO:1901360) | 1.26 | 3 | HNF1B, HNF1A, OGG1 |
regulation of protein localization (GO:0032880) | 2.88 | 3 | HNF1A, OGG1, FLCN |
cellular protein metabolic process (GO:0044267) | 1.63 | 3 | VHL, RNF139, HNF1A |
cellular response to stimulus (GO:0051716) | 1.97 | 3 | VHL, RNF139, OGG1 |
regulation of cell communication (GO:0010646) | 1.73 | 3 | HNF1B, HNF1A, FLCN |
regulation of signal transduction (GO:0009966) | 1.84 | 3 | HNF1B, HNF1A, FLCN |
animal organ development (GO:0048513) | 2.53 | 3 | HNF1B, HNF1A, FLCN |
negative regulation of programmed cell death (GO:0043069) | 3.02 | 3 | VHL, HNF1B, OGG1 |
regulation of cell proliferation (GO:0042127) | 2.41 | 3 | VHL, RNF139, FLCN |
negative regulation of cell proliferation (GO:0008285) | 3.26 | 3 | VHL, RNF139, FLCN |
multicellular organismal process (GO:0032501) | 1.45 | 3 | HNF1B, HNF1A, FLCN |
nucleobase-containing compound metabolic process (GO:0006139) | 1.35 | 3 | HNF1B, HNF1A, OGG1 |
negative regulation of cell death (GO:0060548) | 2.95 | 3 | VHL, HNF1B, OGG1 |
transport (GO:0006810) | 1.51 | 3 | HNF1A, HNF1B, DIRC2 |
cellular aromatic compound metabolic process (GO:0006725) | 1.3 | 3 | HNF1B, HNF1A, OGG1 |
single-organism metabolic process (GO:0044710) | 1.63 | 3 | RNF139, HNF1A, OGG1 |
cellular protein modification process (GO:0006464) | 1.79 | 3 | VHL, RNF139, HNF1A |
regulation of cell differentiation (GO:0045595) | 2.42 | 3 | VHL, HNF1B, FLCN |
protein modification process (GO:0036211) | 1.79 | 3 | VHL, RNF139, HNF1A |
negative regulation of apoptotic process (GO:0043066) | 3.04 | 3 | VHL, HNF1B, OGG1 |
establishment of localization (GO:0051234) | 1.48 | 3 | HNF1A, HNF1B, DIRC2 |
localization (GO:0051179) | 1.4 | 3 | HNF1A, HNF1B, DIRC2 |
heterocycle metabolic process (GO:0046483) | 1.31 | 3 | HNF1B, HNF1A, OGG1 |
response to oxygen-containing compound (GO:1901700) | 2.57 | 3 | HNF1B, HNF1A, OGG1 |
single-multicellular organism process (GO:0044707) | 1.78 | 3 | HNF1B, HNF1A, FLCN |
protein metabolic process (GO:0019538) | 1.45 | 3 | VHL, RNF139, HNF1A |
anatomical structure development (GO:0048856) | 1.58 | 3 | HNF1B, HNF1A, FLCN |
positive regulation of transcription from RNA polymerase II promoter (GO:0045944) | 2.81 | 3 | HNF1B, HNF1A, FLCN |
cellular response to stress (GO:0033554) | 2.51 | 3 | VHL, RNF139, OGG1 |
protein localization (GO:0008104) | 2.36 | 2 | HNF1B, HNF1A |
negative regulation of response to stimulus (GO:0048585) | 2.52 | 2 | OGG1, FLCN |
regulation of Wnt signaling pathway (GO:0030111) | 3.98 | 2 | HNF1B, HNF1A |
small molecule metabolic process (GO:0044281) | 2.38 | 2 | HNF1A, OGG1 |
organic cyclic compound biosynthetic process (GO:1901362) | 1.66 | 2 | HNF1B, HNF1A |
endocrine pancreas development (GO:0031018) | 6.36 | 2 | HNF1B, HNF1A |
single-organism catabolic process (GO:0044712) | 3.21 | 2 | RNF139, OGG1 |
cellular developmental process (GO:0048869) | 1.82 | 2 | VHL, HNF1B |
protein modification by small protein conjugation or removal (GO:0070647) | 2.95 | 2 | VHL, RNF139 |
hormone secretion (GO:0046879) | 5.48 | 2 | HNF1B, HNF1A |
protein modification by small protein conjugation (GO:0032446) | 3.1 | 2 | VHL, RNF139 |
macromolecule localization (GO:0033036) | 2.34 | 2 | HNF1B, HNF1A |
regulation of intracellular transport (GO:0032386) | 3.58 | 2 | RNF139, OGG1 |
establishment of protein localization (GO:0045184) | 2.53 | 2 | HNF1B, HNF1A |
developmental process involved in reproduction (GO:0003006) | 3.36 | 2 | HNF1B, HNF1A |
regulation of pronephros size (GO:0035565) | 9.04 | 2 | HNF1B, HNF1A |
regulation of kidney size (GO:0035564) | 8.12 | 2 | HNF1B, HNF1A |
cellular catabolic process (GO:0044248) | 2.62 | 2 | RNF139, OGG1 |
single organism reproductive process (GO:0044702) | 2.73 | 2 | HNF1B, HNF1A |
organonitrogen compound metabolic process (GO:1901564) | 2.32 | 2 | HNF1A, OGG1 |
response to monosaccharide (GO:0034284) | 4.77 | 2 | HNF1B, HNF1A |
protein ubiquitination (GO:0016567) | 3.28 | 2 | VHL, RNF139 |
aromatic compound biosynthetic process (GO:0019438) | 1.7 | 2 | HNF1B, HNF1A |
regulation of transcription initiation from RNA polymerase II promoter (GO:0060260) | 6.59 | 2 | HNF1B, HNF1A |
positive regulation of transcription initiation from RNA polymerase II promoter (GO:0060261) | 6.9 | 2 | HNF1B, HNF1A |
cellular component assembly (GO:0022607) | 2.14 | 2 | HNF1B, FLCN |
negative regulation of kidney development (GO:0090185) | 6.9 | 2 | HNF1B, FLCN |
regulation of kidney development (GO:0090183) | 5.72 | 2 | HNF1B, FLCN |
secretion by cell (GO:0032940) | 3.59 | 2 | HNF1B, HNF1A |
regulation of protein transport (GO:0051223) | 3.12 | 2 | HNF1A, OGG1 |
nucleic acid-templated transcription (GO:0097659) | 1.91 | 2 | HNF1B, HNF1A |
insulin secretion (GO:0030073) | 6.09 | 2 | HNF1B, HNF1A |
organic substance biosynthetic process (GO:1901576) | 1.34 | 2 | HNF1B, HNF1A |
organic substance catabolic process (GO:1901575) | 2.45 | 2 | RNF139, OGG1 |
regulation of anatomical structure size (GO:0090066) | 3.78 | 2 | HNF1B, HNF1A |
protein secretion (GO:0009306) | 4.97 | 2 | HNF1B, HNF1A |
anatomical structure formation involved in morphogenesis (GO:0048646) | 3.01 | 2 | HNF1B, HNF1A |
heterocycle biosynthetic process (GO:0018130) | 1.7 | 2 | HNF1B, HNF1A |
positive regulation of cellular component organization (GO:0051130) | 2.68 | 2 | HNF1B, HNF1A |
regulation of establishment of protein localization (GO:0070201) | 3.02 | 2 | HNF1A, OGG1 |
regulation of developmental process (GO:0050793) | 2.1 | 2 | HNF1B, FLCN |
amide transport (GO:0042886) | 5.19 | 2 | HNF1B, HNF1A |
regulation of multicellular organismal process (GO:0051239) | 1.87 | 2 | HNF1B, FLCN |
nucleobase-containing compound biosynthetic process (GO:0034654) | 1.72 | 2 | HNF1B, HNF1A |
regulation of protein complex assembly (GO:0043254) | 3.83 | 2 | HNF1B, HNF1A |
RNA metabolic process (GO:0016070) | 1.59 | 2 | HNF1B, HNF1A |
regulation of protein localization to nucleus (GO:1900180) | 4.34 | 2 | OGG1, FLCN |
secretion (GO:0046903) | 3.38 | 2 | HNF1B, HNF1A |
cellular nitrogen compound biosynthetic process (GO:0044271) | 1.59 | 2 | HNF1B, HNF1A |
regulation of protein stability (GO:0031647) | 4.33 | 2 | VHL, RNF139 |
single-organism transport (GO:0044765) | 2.18 | 2 | HNF1B, HNF1A |
regulation of DNA-templated transcription, initiation (GO:2000142) | 6.29 | 2 | HNF1B, HNF1A |
transcription, DNA-templated (GO:0006351) | 1.91 | 2 | HNF1B, HNF1A |
RNA biosynthetic process (GO:0032774) | 1.84 | 2 | HNF1B, HNF1A |
regulation of cellular protein localization (GO:1903827) | 3.43 | 2 | OGG1, FLCN |
cellular biosynthetic process (GO:0044249) | 1.37 | 2 | HNF1B, HNF1A |
peptide transport (GO:0015833) | 5.44 | 2 | HNF1B, HNF1A |
cellular macromolecule biosynthetic process (GO:0034645) | 1.66 | 2 | HNF1B, HNF1A |
response to organic cyclic compound (GO:0014070) | 3.07 | 2 | HNF1B, OGG1 |
negative regulation of protein metabolic process (GO:0051248) | 2.82 | 2 | RNF139, FLCN |
negative regulation of multicellular organismal process (GO:0051241) | 2.84 | 2 | HNF1B, FLCN |
regulation of protein metabolic process (GO:0051246) | 1.93 | 2 | RNF139, FLCN |
positive regulation of protein metabolic process (GO:0051247) | 2.43 | 2 | RNF139, FLCN |
positive regulation of cellular protein metabolic process (GO:0032270) | 2.49 | 2 | RNF139, FLCN |
regulation of protein modification process (GO:0031399) | 2.32 | 2 | RNF139, FLCN |
proteolysis (GO:0006508) | 2.73 | 2 | VHL, RNF139 |
reproductive structure development (GO:0048608) | 4.08 | 2 | HNF1B, HNF1A |
positive regulation of protein complex assembly (GO:0031334) | 4.44 | 2 | HNF1B, HNF1A |
response to oxidative stress (GO:0006979) | 3.9 | 2 | HNF1A, OGG1 |
negative regulation of developmental process (GO:0051093) | 3.17 | 2 | HNF1B, FLCN |
negative regulation of cellular protein metabolic process (GO:0032269) | 2.88 | 2 | RNF139, FLCN |
regulation of cellular protein metabolic process (GO:0032268) | 1.99 | 2 | RNF139, FLCN |
response to drug (GO:0042493) | 3.71 | 2 | HNF1B, OGG1 |
gland development (GO:0048732) | 4.15 | 2 | HNF1B, HNF1A |
positive regulation of protein modification process (GO:0031401) | 2.7 | 2 | RNF139, FLCN |
macromolecular complex subunit organization (GO:0043933) | 2.14 | 2 | HNF1B, HNF1A |
liver development (GO:0001889) | 4.98 | 2 | HNF1B, HNF1A |
hormone transport (GO:0009914) | 5.33 | 2 | HNF1B, HNF1A |
regulation of growth (GO:0040008) | 3.26 | 2 | HNF1B, FLCN |
nitrogen compound transport (GO:0071705) | 3.54 | 2 | HNF1B, HNF1A |
peptide hormone secretion (GO:0030072) | 5.69 | 2 | HNF1B, HNF1A |
organic substance transport (GO:0071702) | 2.15 | 2 | HNF1B, HNF1A |
positive regulation of DNA-templated transcription, initiation (GO:2000144) | 6.55 | 2 | HNF1B, HNF1A |
embryonic morphogenesis (GO:0048598) | 3.72 | 2 | HNF1B, HNF1A |
signal release (GO:0023061) | 4.65 | 2 | HNF1B, HNF1A |
regulation of hormone levels (GO:0010817) | 3.56 | 2 | HNF1B, HNF1A |
reproductive process (GO:0022414) | 2.55 | 2 | HNF1B, HNF1A |
biosynthetic process (GO:0009058) | 1.32 | 2 | HNF1B, HNF1A |
macromolecule biosynthetic process (GO:0009059) | 1.61 | 2 | HNF1B, HNF1A |
catabolic process (GO:0009056) | 2.38 | 2 | RNF139, OGG1 |
single-organism localization (GO:1902578) | 2.09 | 2 | HNF1B, HNF1A |
response to hexose (GO:0009746) | 4.82 | 2 | HNF1B, HNF1A |
response to carbohydrate (GO:0009743) | 4.62 | 2 | HNF1B, HNF1A |
peptide secretion (GO:0002790) | 5.67 | 2 | HNF1B, HNF1A |
response to glucose (GO:0009749) | 4.86 | 2 | HNF1B, HNF1A |
regulation of cellular component biogenesis (GO:0044087) | 3.08 | 2 | HNF1B, HNF1A |
regulation of multicellular organismal development (GO:2000026) | 2.31 | 2 | HNF1B, FLCN |
protein transport (GO:0015031) | 2.62 | 2 | HNF1B, HNF1A |
positive regulation of cellular component biogenesis (GO:0044089) | 3.71 | 2 | HNF1B, HNF1A |