biological regulation (GO:0065007) | 0.39 | 13 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, JPH2, RBM20, SNTA1, PKP2, DSP |
regulation of biological process (GO:0050789) | 0.45 | 13 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, JPH2, RBM20, SNTA1, PKP2, DSP |
cellular process (GO:0009987) | 0.26 | 12 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, JPH2, RBM20, PKP2, DSP |
single-organism process (GO:0044699) | 0.48 | 12 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, JPH2, RBM20, PKP2, DSP |
regulation of cellular process (GO:0050794) | 0.5 | 12 | CACNA1C, RYR2, SCN5A, TTN, KCNH2, VCL, JUP, JPH2, RBM20, SNTA1, PKP2, DSP |
multicellular organismal process (GO:0032501) | 1.45 | 11 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, SNTA1, PKP2, DSP |
single-organism cellular process (GO:0044763) | 0.65 | 11 | CACNA1C, RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, JUP, JPH2, PKP2, DSP |
developmental process (GO:0032502) | 1.36 | 10 | CACNA1C, RYR2, SCN5A, MYH7, TTN, VCL, JUP, RBM20, PKP2, DSP |
regulation of biological quality (GO:0065008) | 1.68 | 10 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JPH2, JUP, SNTA1, PKP2, DSP |
regulation of localization (GO:0032879) | 1.94 | 10 | CACNA1C, RYR2, SCN5A, KCNH2, VCL, JUP, JPH2, SNTA1, PKP2, DSP |
localization (GO:0051179) | 1.4 | 10 | CACNA1C, RYR2, SCN5A, TTN, KCNH2, JPH2, JUP, VCL, PKP2, DSP |
regulation of multicellular organismal process (GO:0051239) | 1.87 | 10 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JPH2, JUP, SNTA1, PKP2, DSP |
regulation of heart contraction (GO:0008016) | 4.35 | 9 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JUP, SNTA1, PKP2, DSP |
regulation of system process (GO:0044057) | 3.53 | 9 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JUP, SNTA1, PKP2, DSP |
anatomical structure development (GO:0048856) | 1.58 | 9 | CACNA1C, RYR2, SCN5A, MYH7, TTN, JUP, RBM20, PKP2, DSP |
single-organism developmental process (GO:0044767) | 1.49 | 9 | CACNA1C, RYR2, SCN5A, MYH7, TTN, VCL, RBM20, PKP2, DSP |
regulation of heart rate (GO:0002027) | 5.29 | 9 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JUP, SNTA1, PKP2, DSP |
regulation of blood circulation (GO:1903522) | 4.05 | 9 | CACNA1C, RYR2, SCN5A, MYH7, KCNH2, JUP, SNTA1, PKP2, DSP |
establishment of localization (GO:0051234) | 1.48 | 9 | CACNA1C, RYR2, SCN5A, TTN, KCNH2, JPH2, JUP, VCL, PKP2 |
regulation of transport (GO:0051049) | 2.24 | 8 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, JUP, SNTA1, PKP2 |
anatomical structure morphogenesis (GO:0009653) | 2.53 | 8 | CACNA1C, RYR2, SCN5A, MYH7, TTN, VCL, PKP2, DSP |
regulation of membrane potential (GO:0042391) | 3.89 | 8 | CACNA1C, RYR2, SCN5A, KCNH2, JUP, SNTA1, PKP2, DSP |
single organism signaling (GO:0044700) | 3.25 | 7 | CACNA1C, RYR2, SCN5A, KCNH2, JUP, PKP2, DSP |
regulation of cellular component movement (GO:0051270) | 3.08 | 7 | CACNA1C, RYR2, SCN5A, VCL, JUP, PKP2, DSP |
muscle contraction (GO:0006936) | 4.37 | 7 | RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, SNTA1 |
single-multicellular organism process (GO:0044707) | 1.78 | 7 | CACNA1C, RYR2, SCN5A, KCNH2, JUP, PKP2, DSP |
regulation of muscle contraction (GO:0006937) | 4.75 | 7 | CACNA1C, RYR2, SCN5A, MYH7, JUP, PKP2, DSP |
transport (GO:0006810) | 1.51 | 7 | CACNA1C, RYR2, SCN5A, TTN, KCNH2, JPH2, VCL |
regulation of metal ion transport (GO:0010959) | 3.94 | 7 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, SNTA1, PKP2 |
muscle system process (GO:0003012) | 4.18 | 7 | RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, SNTA1 |
regulation of striated muscle contraction (GO:0006942) | 5.38 | 7 | CACNA1C, RYR2, SCN5A, MYH7, JUP, PKP2, DSP |
signaling (GO:0023052) | 3.25 | 7 | CACNA1C, RYR2, SCN5A, KCNH2, JUP, PKP2, DSP |
regulation of muscle system process (GO:0090257) | 4.51 | 7 | CACNA1C, RYR2, SCN5A, MYH7, JUP, PKP2, DSP |
positive regulation of biological process (GO:0048518) | 1.2 | 7 | RYR2, SCN5A, KCNH2, JPH2, JUP, PKP2, RBM20 |
single-organism localization (GO:1902578) | 2.09 | 7 | CACNA1C, RYR2, TTN, KCNH2, JPH2, JUP, VCL |
regulation of ion transport (GO:0043269) | 3.4 | 7 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, SNTA1, PKP2 |
system process (GO:0003008) | 2.3 | 7 | RYR2, SCN5A, MYH7, TTN, KCNH2, VCL, SNTA1 |
multicellular organismal signaling (GO:0035637) | 5.36 | 6 | CACNA1C, SCN5A, KCNH2, JUP, PKP2, DSP |
action potential (GO:0001508) | 5.42 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, SNTA1, PKP2 |
regulation of ion transmembrane transport (GO:0034765) | 3.77 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, SNTA1 |
regulation of transmembrane transport (GO:0034762) | 3.74 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, SNTA1 |
regulation of cardiac muscle cell contraction (GO:0086004) | 6.51 | 6 | CACNA1C, RYR2, SCN5A, JUP, PKP2, DSP |
cardiac muscle cell action potential (GO:0086001) | 6.33 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, SNTA1, PKP2 |
cardiac muscle cell action potential involved in contraction (GO:0086002) | 6.47 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, SNTA1, PKP2 |
cardiac conduction (GO:0061337) | 5.54 | 6 | CACNA1C, SCN5A, KCNH2, JUP, PKP2, DSP |
animal organ development (GO:0048513) | 2.53 | 6 | CACNA1C, MYH7, JUP, DSP, PKP2, RBM20 |
regulation of action potential (GO:0098900) | 6.07 | 6 | CACNA1C, RYR2, SCN5A, JUP, PKP2, DSP |
negative regulation of biological process (GO:0048519) | 1.33 | 6 | RYR2, KCNH2, JPH2, VCL, PKP2, SNTA1 |
tissue morphogenesis (GO:0048729) | 3.87 | 6 | RYR2, MYH7, TTN, VCL, PKP2, DSP |
regulation of actin filament-based movement (GO:1903115) | 6.33 | 6 | CACNA1C, RYR2, SCN5A, JUP, PKP2, DSP |
positive regulation of transport (GO:0051050) | 2.9 | 6 | RYR2, SCN5A, KCNH2, JPH2, JUP, PKP2 |
regulation of actin filament-based process (GO:0032970) | 3.97 | 6 | CACNA1C, RYR2, SCN5A, JUP, PKP2, DSP |
single-organism transport (GO:0044765) | 2.18 | 6 | CACNA1C, RYR2, TTN, KCNH2, JPH2, VCL |
regulation of cardiac muscle contraction (GO:0055117) | 5.57 | 6 | CACNA1C, RYR2, SCN5A, JUP, PKP2, DSP |
response to stimulus (GO:0050896) | 1.22 | 6 | RYR2, SCN5A, TTN, KCNH2, JUP, DSP |
regulation of cation transmembrane transport (GO:1904062) | 4.4 | 6 | CACNA1C, RYR2, SCN5A, KCNH2, JPH2, SNTA1 |
regulation of heart rate by cardiac conduction (GO:0086091) | 6.33 | 6 | CACNA1C, SCN5A, KCNH2, JUP, PKP2, DSP |
negative regulation of cellular process (GO:0048523) | 1.41 | 6 | RYR2, KCNH2, JPH2, VCL, PKP2, SNTA1 |
positive regulation of cellular process (GO:0048522) | 1.3 | 6 | RYR2, SCN5A, KCNH2, JPH2, JUP, RBM20 |
regulation of primary metabolic process (GO:0080090) | 1.08 | 5 | RBM20, TTN, JUP, RYR2, SNTA1 |
regulation of metabolic process (GO:0019222) | 1.02 | 5 | RBM20, TTN, JUP, RYR2, SNTA1 |
regulation of cellular metabolic process (GO:0031323) | 1.07 | 5 | RBM20, TTN, JUP, RYR2, SNTA1 |
homeostatic process (GO:0042592) | 2.61 | 5 | CACNA1C, RYR2, KCNH2, PKP2, JPH2 |
cardiac muscle contraction (GO:0060048) | 5.88 | 5 | TTN, SCN5A, RYR2, KCNH2, MYH7 |
cellular component organization or biogenesis (GO:0071840) | 1.22 | 5 | TTN, JUP, PKP2, DSP, VCL |
ventricular cardiac muscle cell action potential (GO:0086005) | 7.02 | 5 | PKP2, SCN5A, SNTA1, KCNH2, RYR2 |
cellular component organization (GO:0016043) | 1.24 | 5 | TTN, JUP, PKP2, DSP, VCL |
organic substance metabolic process (GO:0071704) | 0.63 | 5 | TTN, DSP, KCNH2, MYH7, RBM20 |
inorganic cation transmembrane transport (GO:0098662) | 3.55 | 5 | CACNA1C, SCN5A, RYR2, KCNH2, JPH2 |
regulation of cardiac muscle cell action potential (GO:0098901) | 6.78 | 5 | CACNA1C, JUP, PKP2, RYR2, DSP |
cardiac muscle tissue morphogenesis (GO:0055008) | 5.8 | 5 | TTN, MYH7, RYR2, PKP2, DSP |
cation transport (GO:0006812) | 3.11 | 5 | CACNA1C, KCNH2, RYR2, SCN5A, JPH2 |
ion transport (GO:0006811) | 2.66 | 5 | CACNA1C, SCN5A, RYR2, KCNH2, JPH2 |
inorganic ion transmembrane transport (GO:0098660) | 3.38 | 5 | CACNA1C, KCNH2, RYR2, SCN5A, JPH2 |
positive regulation of ion transport (GO:0043270) | 4.36 | 5 | KCNH2, RYR2, SCN5A, PKP2, JPH2 |
ion transmembrane transport (GO:0034220) | 3.08 | 5 | CACNA1C, KCNH2, RYR2, SCN5A, JPH2 |
metal ion transport (GO:0030001) | 3.36 | 5 | CACNA1C, KCNH2, RYR2, SCN5A, JPH2 |
metabolic process (GO:0008152) | 0.58 | 5 | TTN, RBM20, KCNH2, MYH7, DSP |
response to chemical (GO:0042221) | 1.98 | 5 | TTN, KCNH2, RYR2, SCN5A, JUP |
transmembrane transport (GO:0055085) | 2.72 | 5 | CACNA1C, SCN5A, RYR2, KCNH2, JPH2 |
striated muscle contraction (GO:0006941) | 5.37 | 5 | TTN, SCN5A, RYR2, KCNH2, MYH7 |
primary metabolic process (GO:0044238) | 0.69 | 5 | TTN, RBM20, KCNH2, MYH7, DSP |
regulation of macromolecule metabolic process (GO:0060255) | 1.08 | 5 | RYR2, TTN, SNTA1, JUP, RBM20 |
cellular metabolic process (GO:0044237) | 0.69 | 5 | DSP, TTN, KCNH2, MYH7, RBM20 |
chemical homeostasis (GO:0048878) | 2.97 | 5 | CACNA1C, RYR2, KCNH2, PKP2, JPH2 |
regulation of ventricular cardiac muscle cell action potential (GO:0098911) | 7.33 | 5 | CACNA1C, RYR2, PKP2, JUP, DSP |
cation transmembrane transport (GO:0098655) | 3.43 | 5 | CACNA1C, SCN5A, RYR2, KCNH2, JPH2 |
muscle tissue morphogenesis (GO:0060415) | 5.62 | 5 | TTN, RYR2, PKP2, DSP, MYH7 |
cellular component assembly (GO:0022607) | 2.14 | 4 | TTN, JUP, PKP2, VCL |
single organismal cell-cell adhesion (GO:0016337) | 3.69 | 4 | DSP, JUP, PKP2, VCL |
regulation of cellular localization (GO:0060341) | 3.03 | 4 | CACNA1C, RYR2, JUP, JPH2 |
ventricular cardiac muscle tissue morphogenesis (GO:0055010) | 6.07 | 4 | MYH7, RYR2, PKP2, DSP |
adherens junction organization (GO:0034332) | 5.48 | 4 | DSP, JUP, PKP2, VCL |
ion homeostasis (GO:0050801) | 3.42 | 4 | CACNA1C, RYR2, KCNH2, JPH2 |
cell junction organization (GO:0034330) | 4.51 | 4 | DSP, JUP, PKP2, VCL |
movement of cell or subcellular component (GO:0006928) | 2.61 | 4 | TTN, JUP, MYH7, VCL |
cell adhesion (GO:0007155) | 2.82 | 4 | DSP, JUP, PKP2, VCL |
signal transduction (GO:0007165) | 1.28 | 4 | CACNA1C, RYR2, KCNH2, JUP |
cellular response to chemical stimulus (GO:0070887) | 2.57 | 4 | KCNH2, JUP, SCN5A, RYR2 |
regulation of signaling (GO:0023051) | 1.72 | 4 | CACNA1C, RYR2, JUP, JPH2 |
inorganic ion homeostasis (GO:0098771) | 3.43 | 4 | CACNA1C, RYR2, KCNH2, JPH2 |
cell communication involved in cardiac conduction (GO:0086065) | 6.73 | 4 | CACNA1C, RYR2, SCN5A, PKP2 |
cellular response to stimulus (GO:0051716) | 1.97 | 4 | KCNH2, RYR2, SCN5A, JUP |
regulation of cell communication (GO:0010646) | 1.73 | 4 | CACNA1C, JUP, RYR2, JPH2 |
cellular macromolecule metabolic process (GO:0044260) | 0.93 | 4 | TTN, KCNH2, RBM20, DSP |
regulation of molecular function (GO:0065009) | 1.78 | 4 | TTN, JUP, RYR2, JPH2 |
biological adhesion (GO:0022610) | 2.81 | 4 | DSP, JUP, PKP2, VCL |
single organism cell adhesion (GO:0098602) | 3.63 | 4 | DSP, JUP, PKP2, VCL |
cell-cell adhesion (GO:0098609) | 3.34 | 4 | DSP, JUP, PKP2, VCL |
homotypic cell-cell adhesion (GO:0034109) | 5.76 | 4 | DSP, JUP, PKP2, VCL |
cell-cell junction organization (GO:0045216) | 4.66 | 4 | DSP, JUP, PKP2, VCL |
metal ion homeostasis (GO:0055065) | 3.61 | 4 | CACNA1C, RYR2, KCNH2, JPH2 |
cation homeostasis (GO:0055080) | 3.46 | 4 | CACNA1C, RYR2, KCNH2, JPH2 |
cell communication (GO:0007154) | 3.04 | 4 | CACNA1C, RYR2, SCN5A, PKP2 |
regulation of homeostatic process (GO:0032844) | 3.65 | 4 | CACNA1C, RYR2, SCN5A, JPH2 |
organelle organization (GO:0006996) | 2.02 | 4 | TTN, JUP, PKP2, DSP |
heart development (GO:0007507) | 4.24 | 4 | CACNA1C, PKP2, RBM20, MYH7 |
cytoskeleton organization (GO:0007010) | 3.22 | 4 | TTN, JUP, PKP2, DSP |
macromolecule metabolic process (GO:0043170) | 0.83 | 4 | TTN, KCNH2, DSP, RBM20 |
single-organism organelle organization (GO:1902589) | 2.68 | 4 | TTN, JUP, PKP2, DSP |
regulation of ion homeostasis (GO:2000021) | 4.44 | 4 | CACNA1C, RYR2, SCN5A, JPH2 |
cellular homeostasis (GO:0019725) | 3.23 | 3 | CACNA1C, RYR2, JPH2 |
regulation of RNA metabolic process (GO:0051252) | 1.52 | 3 | JUP, RYR2, RBM20 |
heterotypic cell-cell adhesion (GO:0034113) | 6.43 | 3 | JUP, PKP2, DSP |
cellular cation homeostasis (GO:0030003) | 3.6 | 3 | CACNA1C, RYR2, JPH2 |
regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 6.84 | 3 | KCNH2, SNTA1, SCN5A |
regulation of membrane repolarization (GO:0060306) | 6.4 | 3 | KCNH2, SNTA1, SCN5A |
regulation of calcium ion transmembrane transport (GO:1903169) | 4.98 | 3 | CACNA1C, RYR2, JPH2 |
positive regulation of cytosolic calcium ion concentration (GO:0007204) | 4.56 | 3 | CACNA1C, RYR2, JPH2 |
membrane depolarization (GO:0051899) | 5.62 | 3 | CACNA1C, KCNH2, SCN5A |
cell-cell junction assembly (GO:0007043) | 5.42 | 3 | JUP, PKP2, VCL |
calcium ion homeostasis (GO:0055074) | 3.97 | 3 | CACNA1C, RYR2, JPH2 |
positive regulation of transmembrane transport (GO:0034764) | 4.99 | 3 | RYR2, KCNH2, JPH2 |
cell communication by electrical coupling (GO:0010644) | 7.02 | 3 | CACNA1C, RYR2, PKP2 |
intracellular signal transduction (GO:0035556) | 2.39 | 3 | CACNA1C, RYR2, KCNH2 |
positive regulation of ion transmembrane transport (GO:0034767) | 5.05 | 3 | RYR2, KCNH2, JPH2 |
regulation of response to stimulus (GO:0048583) | 1.54 | 3 | JUP, MYH7, JPH2 |
cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 7.16 | 3 | CACNA1C, RYR2, PKP2 |
regulation of sequestering of calcium ion (GO:0051282) | 5.07 | 3 | CACNA1C, RYR2, JPH2 |
cellular protein metabolic process (GO:0044267) | 1.63 | 3 | TTN, KCNH2, DSP |
membrane depolarization during action potential (GO:0086010) | 6.07 | 3 | CACNA1C, KCNH2, SCN5A |
cellular divalent inorganic cation homeostasis (GO:0072503) | 3.96 | 3 | CACNA1C, RYR2, JPH2 |
response to mechanical stimulus (GO:0009612) | 4.41 | 3 | TTN, JUP, RYR2 |
regulation of calcium ion import (GO:0090279) | 5.08 | 3 | CACNA1C, RYR2, JPH2 |
cellular metal ion homeostasis (GO:0006875) | 3.75 | 3 | CACNA1C, RYR2, JPH2 |
positive regulation of molecular function (GO:0044093) | 2.23 | 3 | JUP, RYR2, JPH2 |
response to calcium ion (GO:0051592) | 4.98 | 3 | TTN, RYR2, SCN5A |
regulation of gene expression (GO:0010468) | 1.37 | 3 | JUP, RYR2, RBM20 |
regulation of calcium ion transport into cytosol (GO:0010522) | 5.23 | 3 | CACNA1C, RYR2, JPH2 |
regulation of cell proliferation (GO:0042127) | 2.41 | 3 | JUP, SCN5A, PKP2 |
cytosolic calcium ion transport (GO:0060401) | 5.74 | 3 | CACNA1C, RYR2, JPH2 |
calcium ion transport into cytosol (GO:0060402) | 5.78 | 3 | CACNA1C, RYR2, JPH2 |
divalent inorganic cation homeostasis (GO:0072507) | 3.9 | 3 | CACNA1C, RYR2, JPH2 |
regulation of nucleobase-containing compound metabolic process (GO:0019219) | 1.43 | 3 | JUP, RYR2, RBM20 |
cellular calcium ion homeostasis (GO:0006874) | 4.01 | 3 | CACNA1C, RYR2, JPH2 |
calcium ion transport (GO:0006816) | 4.33 | 3 | CACNA1C, RYR2, JPH2 |
cellular ion homeostasis (GO:0006873) | 3.57 | 3 | CACNA1C, RYR2, JPH2 |
establishment of protein localization (GO:0045184) | 2.53 | 3 | JUP, PKP2, RYR2 |
macromolecule modification (GO:0043412) | 1.73 | 3 | TTN, KCNH2, DSP |
protein modification process (GO:0036211) | 1.79 | 3 | TTN, KCNH2, DSP |
cellular protein modification process (GO:0006464) | 1.79 | 3 | TTN, KCNH2, DSP |
response to metal ion (GO:0010038) | 3.91 | 3 | TTN, RYR2, SCN5A |
establishment of localization in cell (GO:0051649) | 2.47 | 3 | CACNA1C, RYR2, JPH2 |
desmosome organization (GO:0002934) | 7.53 | 3 | JUP, PKP2, DSP |
divalent metal ion transport (GO:0070838) | 4.15 | 3 | CACNA1C, RYR2, JPH2 |
cellular chemical homeostasis (GO:0055082) | 3.4 | 3 | CACNA1C, RYR2, JPH2 |
response to inorganic substance (GO:0010035) | 3.56 | 3 | TTN, RYR2, SCN5A |
cell junction assembly (GO:0034329) | 4.86 | 3 | JUP, PKP2, VCL |
bundle of His cell-Purkinje myocyte adhesion involved in cell communication (GO:0086073) | 7.94 | 3 | JUP, PKP2, DSP |
response to abiotic stimulus (GO:0009628) | 2.8 | 3 | TTN, JUP, RYR2 |
divalent inorganic cation transport (GO:0072511) | 4.13 | 3 | CACNA1C, RYR2, JPH2 |
detection of stimulus (GO:0051606) | 3.22 | 3 | TTN, JUP, RYR2 |
response to external stimulus (GO:0009605) | 2.55 | 3 | TTN, JUP, RYR2 |
protein metabolic process (GO:0019538) | 1.45 | 3 | TTN, KCNH2, DSP |
regulation of release of sequestered calcium ion into cytosol (GO:0051279) | 5.44 | 3 | CACNA1C, RYR2, JPH2 |
regulation of calcium ion transport (GO:0051924) | 4.38 | 3 | CACNA1C, RYR2, JPH2 |
calcium ion transmembrane transport (GO:0070588) | 4.67 | 3 | CACNA1C, RYR2, JPH2 |
cardiac muscle cell-cardiac muscle cell adhesion (GO:0086042) | 7.94 | 3 | JUP, PKP2, DSP |
regulation of cytosolic calcium ion concentration (GO:0051480) | 4.41 | 3 | CACNA1C, RYR2, JPH2 |
phosphate-containing compound metabolic process (GO:0006796) | 2.16 | 3 | TTN, KCNH2, MYH7 |
regulation of cardiac muscle cell membrane repolarization (GO:0099623) | 6.68 | 3 | KCNH2, SNTA1, SCN5A |
regulation of sodium ion transport (GO:0002028) | 5.4 | 3 | SNTA1, SCN5A, PKP2 |
phosphorus metabolic process (GO:0006793) | 2.15 | 3 | TTN, KCNH2, MYH7 |
positive regulation of cation transmembrane transport (GO:1904064) | 5.17 | 3 | RYR2, KCNH2, JPH2 |
regulation of nitrogen compound metabolic process (GO:0051171) | 1.36 | 3 | JUP, RYR2, RBM20 |
protein localization (GO:0008104) | 2.36 | 2 | DSP, VCL |
positive regulation of response to stimulus (GO:0048584) | 2.18 | 2 | JUP, JPH2 |
positive regulation of homeostatic process (GO:0032846) | 4.38 | 2 | RYR2, JPH2 |
negative regulation of homeostatic process (GO:0032845) | 4.91 | 2 | RYR2, JPH2 |
membrane depolarization during AV node cell action potential (GO:0086045) | 8.34 | 2 | CACNA1C, SCN5A |
membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 7.09 | 2 | CACNA1C, SCN5A |
establishment of protein localization to plasma membrane (GO:0090002) | 5.2 | 2 | JUP, PKP2 |
organic cyclic compound metabolic process (GO:1901360) | 1.26 | 2 | RBM20, MYH7 |
single-organism metabolic process (GO:0044710) | 1.63 | 2 | KCNH2, MYH7 |
regulation of signal transduction (GO:0009966) | 1.84 | 2 | JUP, JPH2 |
positive regulation of signal transduction (GO:0009967) | 2.5 | 2 | JUP, JPH2 |
release of sequestered calcium ion into cytosol (GO:0051209) | 6.04 | 2 | RYR2, JPH2 |
cellular developmental process (GO:0048869) | 1.82 | 2 | TTN, DSP |
phosphorylation (GO:0016310) | 2.63 | 2 | TTN, KCNH2 |
macromolecule localization (GO:0033036) | 2.34 | 2 | DSP, VCL |
regulation of sodium ion transmembrane transport (GO:1902305) | 5.86 | 2 | SNTA1, SCN5A |
calcium-mediated signaling (GO:0019722) | 5.24 | 2 | CACNA1C, RYR2 |
negative regulation of sequestering of calcium ion (GO:0051283) | 6.04 | 2 | RYR2, JPH2 |
muscle filament sliding (GO:0030049) | 6.09 | 2 | TTN, MYH7 |
actin filament-based movement (GO:0030048) | 5.54 | 2 | TTN, MYH7 |
calcium ion import into cytosol (GO:1902656) | 5.99 | 2 | RYR2, JPH2 |
regulation of RNA biosynthetic process (GO:2001141) | 1.55 | 2 | JUP, RYR2 |
response to organic substance (GO:0010033) | 2.2 | 2 | JUP, RYR2 |
heterocycle metabolic process (GO:0046483) | 1.31 | 2 | RBM20, MYH7 |
intermediate filament organization (GO:0045109) | 6.73 | 2 | PKP2, DSP |
intermediate filament cytoskeleton organization (GO:0045104) | 6.04 | 2 | PKP2, DSP |
response to organonitrogen compound (GO:0010243) | 3.2 | 2 | JUP, RYR2 |
intermediate filament-based process (GO:0045103) | 6.02 | 2 | PKP2, DSP |
positive regulation of heart contraction (GO:0045823) | 6.15 | 2 | RYR2, SCN5A |
regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) | 6.68 | 2 | CACNA1C, RYR2 |
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO:0010881) | 6.9 | 2 | CACNA1C, RYR2 |
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) | 6.59 | 2 | CACNA1C, RYR2 |
positive regulation of ion transmembrane transporter activity (GO:0032414) | 5.55 | 2 | RYR2, JPH2 |
positive regulation of transporter activity (GO:0032411) | 5.44 | 2 | RYR2, JPH2 |
regulation of ion transmembrane transporter activity (GO:0032412) | 4.55 | 2 | RYR2, JPH2 |
detection of external stimulus (GO:0009581) | 4.98 | 2 | TTN, JUP |
detection of abiotic stimulus (GO:0009582) | 4.96 | 2 | TTN, JUP |
secretion by cell (GO:0032940) | 3.59 | 2 | TTN, VCL |
nitrogen compound metabolic process (GO:0006807) | 1.13 | 2 | RBM20, MYH7 |
second-messenger-mediated signaling (GO:0019932) | 4.65 | 2 | CACNA1C, RYR2 |
regulation of protein transport (GO:0051223) | 3.12 | 2 | CACNA1C, JUP |
response to muscle stretch (GO:0035994) | 6.78 | 2 | TTN, RYR2 |
exocytosis (GO:0006887) | 4.11 | 2 | TTN, VCL |
regulated exocytosis (GO:0045055) | 4.44 | 2 | TTN, VCL |
macromolecular complex assembly (GO:0065003) | 2.55 | 2 | TTN, JUP |
positive regulation of calcium ion transmembrane transport (GO:1904427) | 5.69 | 2 | RYR2, JPH2 |
calcium ion transmembrane import into cytosol (GO:0097553) | 5.99 | 2 | RYR2, JPH2 |
regulation of establishment of protein localization (GO:0070201) | 3.02 | 2 | CACNA1C, JUP |
regulation of catalytic activity (GO:0050790) | 1.97 | 2 | TTN, RYR2 |
regulation of biosynthetic process (GO:0009889) | 1.37 | 2 | JUP, RYR2 |
positive regulation of blood circulation (GO:1903524) | 5.16 | 2 | RYR2, SCN5A |
secretion (GO:0046903) | 3.38 | 2 | TTN, VCL |
regulation of transmembrane transporter activity (GO:0022898) | 4.52 | 2 | RYR2, JPH2 |
response to nitrogen compound (GO:1901698) | 3.12 | 2 | JUP, RYR2 |
cellular response to nitrogen compound (GO:1901699) | 3.79 | 2 | JUP, RYR2 |
response to stress (GO:0006950) | 1.8 | 2 | RYR2, DSP |
regulation of transcription, DNA-templated (GO:0006355) | 1.56 | 2 | JUP, RYR2 |
muscle hypertrophy (GO:0014896) | 6.68 | 2 | TTN, RYR2 |
striated muscle hypertrophy (GO:0014897) | 6.78 | 2 | TTN, RYR2 |
regulation of cell motility (GO:2000145) | 3.16 | 2 | PKP2, VCL |
negative regulation of cell motility (GO:2000146) | 4.36 | 2 | PKP2, VCL |
cardiac muscle hypertrophy (GO:0003300) | 6.84 | 2 | TTN, RYR2 |
positive regulation of signaling (GO:0023056) | 2.41 | 2 | JUP, JPH2 |
cellular nitrogen compound metabolic process (GO:0034641) | 1.22 | 2 | RBM20, MYH7 |
positive regulation of cell communication (GO:0010647) | 2.41 | 2 | JUP, JPH2 |
response to organic cyclic compound (GO:0014070) | 3.07 | 2 | JUP, RYR2 |
regulation of protein localization (GO:0032880) | 2.88 | 2 | CACNA1C, JUP |
response to endogenous stimulus (GO:0009719) | 2.79 | 2 | JUP, RYR2 |
nucleobase-containing compound metabolic process (GO:0006139) | 1.35 | 2 | RBM20, MYH7 |
positive regulation of multicellular organismal process (GO:0051240) | 2.49 | 2 | RYR2, SCN5A |
regulation of protein metabolic process (GO:0051246) | 1.93 | 2 | TTN, SNTA1 |
actin-myosin filament sliding (GO:0033275) | 6.09 | 2 | TTN, MYH7 |
regulation of the force of heart contraction (GO:0002026) | 6.4 | 2 | RYR2, MYH7 |
macromolecular complex subunit organization (GO:0043933) | 2.14 | 2 | TTN, JUP |
regulation of transporter activity (GO:0032409) | 4.45 | 2 | RYR2, JPH2 |
regulation of protein modification process (GO:0031399) | 2.32 | 2 | TTN, SNTA1 |
monovalent inorganic cation transport (GO:0015672) | 3.74 | 2 | KCNH2, SCN5A |
positive regulation of sodium ion transport (GO:0010765) | 6.23 | 2 | PKP2, SCN5A |
cellular response to endogenous stimulus (GO:0071495) | 3.33 | 2 | JUP, RYR2 |
regulation of calcium ion transmembrane transporter activity (GO:1901019) | 5.49 | 2 | RYR2, JPH2 |
cellular aromatic compound metabolic process (GO:0006725) | 1.3 | 2 | RBM20, MYH7 |
negative regulation of locomotion (GO:0040013) | 4.22 | 2 | PKP2, VCL |
regulation of nucleic acid-templated transcription (GO:1903506) | 1.55 | 2 | JUP, RYR2 |
cell-cell signaling involved in cardiac conduction (GO:0086019) | 8.12 | 2 | RYR2, PKP2 |
epithelial cell-cell adhesion (GO:0090136) | 7.09 | 2 | JUP, VCL |
regulation of cellular protein metabolic process (GO:0032268) | 1.99 | 2 | TTN, SNTA1 |
cellular response to organic cyclic compound (GO:0071407) | 3.93 | 2 | JUP, RYR2 |
adherens junction assembly (GO:0034333) | 6.2 | 2 | JUP, VCL |
regulation of cellular biosynthetic process (GO:0031326) | 1.38 | 2 | JUP, RYR2 |
morphogenesis of an epithelium (GO:0002009) | 4.08 | 2 | RYR2, VCL |
protein complex subunit organization (GO:0071822) | 2.6 | 2 | TTN, JUP |
detection of mechanical stimulus (GO:0050982) | 5.94 | 2 | TTN, JUP |
platelet degranulation (GO:0002576) | 5.12 | 2 | TTN, VCL |
regulation of cellular macromolecule biosynthetic process (GO:2000112) | 1.46 | 2 | JUP, RYR2 |
cellular response to organic substance (GO:0071310) | 2.78 | 2 | JUP, RYR2 |
regulation of macromolecule biosynthetic process (GO:0010556) | 1.43 | 2 | JUP, RYR2 |
positive regulation of calcium ion transmembrane transporter activity (GO:1901021) | 6.36 | 2 | RYR2, JPH2 |
positive regulation of heart rate (GO:0010460) | 6.59 | 2 | RYR2, SCN5A |
skin development (GO:0043588) | 5.84 | 2 | JUP, DSP |
embryonic morphogenesis (GO:0048598) | 3.72 | 2 | CACNA1C, RYR2 |
negative regulation of cell migration (GO:0030336) | 4.41 | 2 | PKP2, VCL |
protein phosphorylation (GO:0006468) | 2.89 | 2 | TTN, KCNH2 |
regulation of cell migration (GO:0030334) | 3.23 | 2 | PKP2, VCL |
actin filament-based process (GO:0030029) | 3.94 | 2 | TTN, MYH7 |
protein complex assembly (GO:0006461) | 2.78 | 2 | TTN, JUP |
desmosome assembly (GO:0002159) | 8.34 | 2 | JUP, PKP2 |
cell-cell signaling (GO:0007267) | 3.35 | 2 | RYR2, PKP2 |
calcium ion import (GO:0070509) | 5.57 | 2 | RYR2, JPH2 |
response to oxygen-containing compound (GO:1901700) | 2.57 | 2 | JUP, RYR2 |
cellular response to oxygen-containing compound (GO:1901701) | 3.22 | 2 | JUP, RYR2 |
negative regulation of cellular component movement (GO:0051271) | 4.22 | 2 | PKP2, VCL |
regulation of locomotion (GO:0040012) | 3.12 | 2 | PKP2, VCL |
positive regulation of calcium ion transport (GO:0051928) | 5.06 | 2 | RYR2, JPH2 |
establishment of protein localization to membrane (GO:0090150) | 4.14 | 2 | JUP, PKP2 |
actin-mediated cell contraction (GO:0070252) | 5.88 | 2 | TTN, MYH7 |
cellular response to organonitrogen compound (GO:0071417) | 3.87 | 2 | JUP, RYR2 |
vesicle-mediated transport (GO:0016192) | 2.72 | 2 | TTN, VCL |