Disease table of LEIGH SYNDROME OMIM ID: 256000

Gene-disease associations table

Gene	Associated with LEIGH SYNDROME in	Link to HGNC	Cytogenetic band	Number of associated diseases	Associated diseases
MT-CO3	ClinVar	HGNC link	MT	4	540000, 550500, 535000, 256000
POLG	HUMSAVAR	HGNC link	15q26.1	4	PS157640, 607459, PS603041, 256000
NDUFAF6	OMIM	HGNC link	8q22.1	2	256000, 252010
NDUFAF2	OMIM	HGNC link	5q12.1	2	256000, 252010
NDUFV1	HUMSAVAR	HGNC link	11q13.2	2	256000, 252010
MT-ND3	HUMSAVAR	HGNC link	MT	3	256000, 252010, 500001
MT-ND5	HUMSAVAR	HGNC link	MT	6	535000, 256000, 520100, 540000, 545000, 252010
BCS1L	OMIM	HGNC link	2q35	4	124000, 262000, 603358, 256000
FOXRED1	OMIM	HGNC link	11q24.2	2	256000, 252010
NDUFA10	OMIM	HGNC link	2q37.3	1	256000
NDUFA12	OMIM	HGNC link	12q22	1	256000
SURF1	ClinVar, OMIM, HUMSAVAR	HGNC link	9q34.2	3	PS118220, PS601462, 256000
MT-ATP6	HUMSAVAR	HGNC link	MT	5	535000, 256000, 551500, 500003, 500011
NDUFA2	OMIM	HGNC link	5q31.3	1	256000
MTFMT	ClinVar	HGNC link	15q22.31	2	PS609060, 256000
NARS2	HUMSAVAR	HGNC link	11q14.1	2	PS609060, 256000
IARS2	ClinVar	HGNC link	1q41	2	256000, 616007
NDUFA9	OMIM	HGNC link	12p13.32	1	256000
COX10	OMIM	HGNC link	17p12	3	256000, 220110, PS601462
SDHA	OMIM, HUMSAVAR	HGNC link	5p15.33	5	252011, 604287, PS115200, PS168000, 256000
NDUFAF5	HUMSAVAR	HGNC link	20p12.1	2	256000, 252010
ECHS1	ClinVar	HGNC link	10q26.3	2	256000, 616277
NDUFS3	OMIM	HGNC link	11p11.2	2	256000, 252010
NDUFS4	OMIM	HGNC link	5q11.2	2	256000, 252010
NDUFS7	OMIM	HGNC link	19p13.3	2	256000, 252010
NDUFS8	ClinVar, OMIM, HUMSAVAR	HGNC link	11q13.2	1	256000
COX15	OMIM, HUMSAVAR	HGNC link	10q24.2	3	256000, PS601462, 615119

Download the disease annotation in CSV format

Relations among genes:

Tandem repeat annotations from DGD

Cytogenetic band analysis

By sub-band

Shared sub_band	Number of genes associated with the disease	Genes associated with the disease
11q13.2	2	NDUFS8, NDUFV1

By band

Shared band	Number of genes associated with the disease	Genes associated with the disease
11q13	2	NDUFS8, NDUFV1

By region

Shared region	Number of genes associated with the disease	Genes associated with the disease
2q3	2	BCS1L, NDUFA10
11q1	3	NDUFS8, NARS2, NDUFV1
10q2	2	ECHS1, COX15
5q1	2	NDUFS4, NDUFAF2
15q2	2	POLG, MTFMT

By arm

Shared arm	Number of genes associated with the disease	Genes associated with the disease
15q	2	POLG, MTFMT
10q	2	ECHS1, COX15
2q	2	BCS1L, NDUFA10
5q	3	NDUFS4, NDUFA2, NDUFAF2
11q	4	FOXRED1, NDUFS8, NARS2, NDUFV1

By chromosome

Shared chromosome	Number of genes associated with the disease	Genes associated with the disease
11	5	FOXRED1, NDUFS3, NARS2, NDUFV1, NDUFS8
10	2	ECHS1, COX15
12	2	NDUFA9, NDUFA12
15	2	POLG, MTFMT
2	2	BCS1L, NDUFA10
5	4	SDHA, NDUFS4, NDUFA2, NDUFAF2

Transcription Factors (TF) annotation from TRRUST

regulated gene	associated to this disease	# TFs	TFs	# TFs associated with this disease	TFs associated with this disease
NDUFV1	YES	1	SP1	0
SURF1	YES	2	MYC, YY1	0

Interactions from BIOGRID - physical

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
POLG	NARS2	No	1	OXLD1
POLG	NDUFAF5	No	1	OXLD1
NDUFAF2	NDUFA2	No	1	CDV3
NDUFV1	BCS1L	No	2	VAPA, UQCRFS1
NDUFV1	FOXRED1	No	1	NDUFS5
NDUFV1	NDUFA10	Yes	11	GOLT1B, SDHB, NDUFV2, RMDN3, NDUFA9, NDUFS2, RAB5C, NDUFA11, UQCRB, NDUFA12, VAPA
NDUFV1	NDUFA12	Yes	33	BMPR1A, NDUFV2, RMDN3, ND1, ATP1B1, UQCRB, NDUFS5, NDUFS4, VAPA, VDAC2, NDUFS1, NDUFA13, NDUFA2, NDUFS7, NDUFB4, NDUFS3, TIMMDC1, NDUFS6, NDUFS2, RAB5C, NDUFA11, NDUFB6, NDUFB8, NDUFA10, GOLT1B, NDUFB10, NDUFA9, NDUFA8, ND5, UQCRFS1, SDHB, NDUFS8, NDUFV3
NDUFV1	SURF1	No	6	NDUFS8, NDUFV2, ABCD3, NDUFA12, NDUFB8, NDUFS3
NDUFV1	NDUFA2	Yes	22	ILF3, NDUFV2, RMDN3, TOMM40, ATP1B1, NDUFA8, NDUFS5, VAPA, CPT1A, NDUFA12, NDUFS6, RAB5C, NDUFA11, SDHA, NDUFS4, NDUFS3, GOLT1B, ICT1, NDUFA9, ATP6V0D1, SDHB, PHB2
NDUFV1	IARS2	No	1	ILF3
NDUFV1	NDUFA9	Yes	28	NDUFS8, NDUFV2, NDUFA8, NDUFS5, NDUFB8, VAPA, VDAC2, NDUFS1, ICT1, NDUFA13, NDUFA2, NDUFS7, NDUFB4, NDUFS3, NDUFA12, NDUFS6, TIMMDC1, ATP5F1, NDUFS2, NDUFA11, NDUFS4, NDUFA10, GOLT1B, NDUFB10, ND5, UQCRFS1, SDHB, NDUFV3
NDUFV1	SDHA	Yes	16	ATP5F1, NDUFS2, NDUFV2, ICT1, OXCT1, PDHA1, NDUFS8, ATP1B1, NDUFA2, COPS5, NDUFS3, SDHB, NDUFS6, UQCRFS1, MTCH1, UQCRB
NDUFV1	NDUFAF5	No	3	NDUFS7, NDUFA10, NDUFS3
NDUFV1	NDUFS3	Yes	26	NDUFS8, NPHP1, NDUFV2, ND1, ATP1B1, NDUFS5, NDUFB8, NDUFS1, ICT1, NDUFA13, NDUFA2, NDUFS7, NDUFB4, NDUFA12, NDUFS6, ADRB2, NDUFS2, NDUFA11, SDHA, NDUFB6, NDUFS4, GOLT1B, NDUFB10, NDUFA9, ND5, NDUFV3
NDUFV1	NDUFS4	Yes	29	ND1, NDUFV2, NDUFS8, UQCRB, NDUFS5, VAPA, VDAC2, NDUFS1, NDUFA13, NDUFA2, NDUFS7, NDUFB4, NDUFA12, NDUFS6, ATP5F1, NDUFS2, NDUFA11, NDUFA8, NDUFB8, ATP1A1, NDUFS3, GOLT1B, NDUFB10, ABCD3, ATP6V0D1, ND5, SDHB, NDUFA9, NDUFV3
NDUFV1	NDUFS7	Yes	17	NDUFS2, NDUFB10, NDUFV2, ATP5F1, NDUFA12, NDUFA9, NDUFA13, NDUFS8, NDUFS7, NDUFA11, NDUFA8, NDUFS3, TIMMDC1, NDUFS5, NDUFS6, NDUFS4, NDUFS1
NDUFV1	NDUFS8	Yes	19	GOLT1B, TIMMDC1, ICT1, NDUFA12, NDUFS1, NDUFA9, NDUFS5, NDUFS2, NDUFS7, NDUFA11, NDUFA8, VAPA, SDHB, NDUFS3, NDUFS6, NDUFV2, NDUFS4, PHB2, SDHA
NDUFV1	COX15	No	5	NDUFS8, NDUFS6, NDUFA9, NDUFS4, NDUFA12
BCS1L	NDUFA10	No	1	VAPA
BCS1L	NDUFA12	No	2	VAPA, UQCRFS1
BCS1L	NDUFA2	No	1	VAPA
BCS1L	NDUFA9	No	2	VAPA, UQCRFS1
BCS1L	SDHA	No	1	UQCRFS1
BCS1L	NDUFS4	No	1	VAPA
BCS1L	NDUFS8	No	1	VAPA
FOXRED1	NDUFA12	No	1	NDUFS5
FOXRED1	SURF1	No	2	NXF1, MOV10
FOXRED1	NDUFA2	No	1	NDUFS5
FOXRED1	NDUFA9	No	1	NDUFS5
FOXRED1	SDHA	No	1	NXF1
FOXRED1	ECHS1	No	2	NXF1, MOV10
FOXRED1	NDUFS3	No	4	NXF1, SHMT2, NDUFS5, MOV10
FOXRED1	NDUFS4	No	1	NDUFS5
FOXRED1	NDUFS7	No	1	NDUFS5
FOXRED1	NDUFS8	No	1	NDUFS5
NDUFA10	NDUFA12	Yes	14	SDHB, GOLT1B, NDUFB7, NDUFV2, RMDN3, NDUFA9, NDUFS2, RAB5C, NDUFA11, UQCRB, MPV17, NDUFV1, IMMT, VAPA
NDUFA10	SURF1	No	2	NDUFA12, NDUFV2
NDUFA10	NDUFA2	No	14	GOLT1B, SDHB, NDUFV2, NDUFA12, RMDN3, NDUFA9, UQCRQ, RAB5C, NDUFA11, COX4I1, NDUFB7, NDUFV1, ABCC2, VAPA
NDUFA10	IARS2	No	1	NTRK1
NDUFA10	NDUFA9	Yes	14	SDHB, GOLT1B, NDUFA12, NDUFV2, IMMT, NDUFS2, RNF2, NDUFA11, NDUFB7, NTRK1, NDUFV1, ABCC2, MME, VAPA
NDUFA10	SDHA	No	7	NDUFS2, NDUFV2, UQCRQ, UQCRB, SDHB, NTRK1, NDUFV1
NDUFA10	NDUFAF5	Yes	0
NDUFA10	ECHS1	No	2	NTRK1, COX4I1
NDUFA10	NDUFS3	No	12	GOLT1B, NDUFA12, NDUFV2, PARK2, NDUFA9, UQCRQ, NDUFS2, NDUFA11, NDUFB7, NTRK1, NDUFV1, NDUFAF5
NDUFA10	NDUFS4	No	12	NDUFS2, NDUFA12, NDUFV2, NDUFA9, PARK2, GOLT1B, NDUFA11, COX4I1, SDHB, NDUFV1, VAPA, UQCRB
NDUFA10	NDUFS7	No	8	NDUFS2, NDUFA12, NDUFV2, NDUFA9, NDUFA11, MPV17, NDUFV1, NDUFAF5
NDUFA10	NDUFS8	No	12	GOLT1B, SDHB, NDUFV2, NDUFA12, NDUFA9, UQCRQ, NDUFS2, NDUFA11, MPV17, NDUFV1, ABCC2, VAPA
NDUFA10	COX15	No	2	NDUFA9, NDUFA12
NDUFA12	SURF1	Yes	7	NDUFS8, COX15, NDUFV2, CYC1, NDUFB8, UQCRC1, NDUFS3
NDUFA12	NDUFA2	Yes	24	ATP5B, NDUFV2, RMDN3, NDUFB11, ATP1B3, MTCH2, NDUFS5, TMED2, VAPA, NDUFB7, NDUFV1, RAB5C, NDUFA11, ATP1B1, NDUFA8, NDUFS4, NDUFS6, NDUFS3, GOLT1B, NDUFA9, CISD1, NDUFB9, MMGT1, SDHB
NDUFA12	NDUFA9	Yes	38	NDUFS8, UQCRC2, NDUFV2, NDUFB11, NDUFB9, NDUFS5, IMMT, VAPA, VDAC2, NDUFS1, NDUFA13, ND5, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA6, COX15, TIMMDC1, NDUFA5, NDUFS2, NDUFA11, NDUFA8, NDUFB8, NDUFV1, NDUFA10, SDHB, GOLT1B, NDUFB10, NDUFB4, NDUFS4, ATP1B3, NDUFA2, NDUFS6, UQCRFS1, NDUFB3, NDUFB5, NDUFV3
NDUFA12	SDHA	No	12	NDUFS2, NDUFV2, UQCRFS1, NDUFS8, CYC1, NDUFA2, ATP1B1, SDHB, NDUFV1, NDUFS6, NDUFS3, UQCRB
NDUFA12	NDUFAF5	No	3	NDUFS7, NDUFA10, NDUFS3
NDUFA12	NDUFS3	Yes	35	ND1, UQCRC2, NDUFV2, NDUFS8, NDUFB11, NDUFB9, MTCH2, NDUFS5, NDUFS4, NDUFS1, NDUFA13, NDUFA5, NDUFS7, NDUFA7, SURF1, NDUFB7, NDUFV1, CYC1, NDUFS2, NDUFA11, NDUFAF1, ATP1B1, NDUFB6, NDUFB8, NDUFS6, GOLT1B, NDUFB10, NDUFB4, NDUFA9, ATP1B3, NDUFA2, ND5, NDUFB3, NDUFB5, NDUFV3
NDUFA12	NDUFS4	Yes	33	ND1, NDUFS5, NDUFV2, NDUFS8, CYC1, UQCRB, MRPL15, VAPA, VDAC2, NDUFS1, ATP5C1, NDUFA13, ND5, NDUFS7, NDUFA7, NDUFV1, COX15, NDUFS2, NDUFA11, UQCRC2, NDUFB8, UQCRH, NDUFS3, GOLT1B, NDUFB10, NDUFB4, NDUFA9, NDUFA8, NDUFA2, NDUFS6, SDHB, NDUFB5, NDUFV3
NDUFA12	NDUFS7	Yes	19	MPV17, NDUFS2, NDUFB10, NDUFS1, NDUFV2, NDUFS5, NDUFS4, NDUFS8, NDUFA13, NDUFA8, NDUFS7, NDUFA11, NDUFA5, NDUFS6, NDUFA9, TIMMDC1, NDUFB5, NDUFV1, NDUFS3
NDUFA12	NDUFS8	Yes	23	NDUFV2, CYC1, NDUFA8, NDUFS5, TMED2, VAPA, NDUFS1, NDUFS7, TIMMDC1, NDUFS6, COX15, MPV17, NDUFS2, SLC25A3, NDUFA11, UQCRC2, NDUFS4, NDUFV1, NDUFS3, GOLT1B, NDUFA9, SURF1, SDHB
NDUFA12	COX15	Yes	7	NDUFS8, NDUFA9, CYC1, SURF1, MRPL15, NDUFS4, NDUFS6
SURF1	NDUFA2	No	3	NDUFS3, NDUFV2, NDUFA12
SURF1	NDUFA9	No	6	NDUFS8, COX15, NDUFV2, NDUFA12, NDUFB8, NDUFS3
SURF1	SDHA	No	6	NDUFS8, NDUFV2, SAMM50, CYC1, NXF1, NDUFS3
SURF1	NDUFAF5	No	2	NDUFAF3, NDUFS3
SURF1	ECHS1	No	3	ABCC1, NXF1, MOV10
SURF1	NDUFS3	Yes	9	NDUFS8, NDUFAF3, NDUFV2, CYC1, SAMM50, NDUFA12, NDUFB8, NXF1, MOV10
SURF1	NDUFS4	No	9	NDUFS8, COX15, NDUFA12, NDUFV2, ABCD3, CYC1, NDUFAF3, NDUFB8, NDUFS3
SURF1	NDUFS7	No	5	NDUFAF3, NDUFS8, NDUFS3, NDUFV2, NDUFA12
SURF1	NDUFS8	Yes	7	COX15, NDUFA12, NDUFV2, CYC1, SAMM50, NDUFAF3, NDUFS3
SURF1	COX15	Yes	3	NDUFS8, NDUFA12, CYC1
NDUFA2	MTFMT	No	1	APP
NDUFA2	IARS2	No	2	ILF3, APP
NDUFA2	NDUFA9	Yes	19	GOLT1B, FN1, NDUFV2, ICT1, NDUFS5, NDUFS4, NDUFA12, ATP1B3, NDUFB11, NDUFA11, NDUFB9, VAPA, NDUFB7, SDHB, NDUFA8, NDUFV1, ABCC2, NDUFS6, NDUFS3
NDUFA2	SDHA	Yes	10	FN1, ICT1, NDUFV2, UQCRQ, ATP1B1, NDUFS3, SDHB, NDUFV1, NDUFS6, ITGA4
NDUFA2	NDUFAF5	No	2	NDUFS3, MRPL43
NDUFA2	ECHS1	No	1	COX4I1
NDUFA2	NDUFS3	Yes	21	NDUFA11, GOLT1B, FN1, NDUFV2, ICT1, NDUFA12, NDUFA9, UQCRQ, ATP1B3, NDUFB11, NDUFS5, ACAD9, NDUFB9, NDUFS6, MTCH2, SDHA, NDUFB7, ATP1B1, NDUFV1, NDUFS4, ITGA4
NDUFA2	NDUFS4	Yes	15	GOLT1B, SDHB, NDUFV2, NDUFS5, NDUFA9, NDUFA8, ATP6V0D1, NDUFA11, COX4I1, APP, NDUFA12, NDUFS3, NDUFV1, NDUFS6, VAPA
NDUFA2	NDUFS7	No	11	NDUFA11, NDUFS5, NDUFV2, NDUFS4, NDUFA9, ACAD9, NDUFA8, NDUFA12, NDUFV1, NDUFS6, NDUFS3
NDUFA2	NDUFS8	No	19	GOLT1B, NDUFV2, ICT1, NDUFA12, NDUFS4, NDUFA9, UQCRQ, SDHA, NDUFS5, NDUFA11, NDUFA8, VAPA, SDHB, NDUFS3, TMED2, NDUFV1, ABCC2, NDUFS6, PHB2
NDUFA2	COX15	No	5	NDUFS4, LAMTOR3, NDUFS6, NDUFA12, NDUFA9
MTFMT	IARS2	No	1	APP
MTFMT	NDUFA9	No	1	ELAVL1
MTFMT	NDUFS4	No	1	APP
NARS2	NDUFAF5	No	1	OXLD1
IARS2	NDUFA9	No	1	NTRK1
IARS2	SDHA	No	3	NTRK1, HSPB1, SIRT7
IARS2	ECHS1	No	2	NTRK1, YWHAQ
IARS2	NDUFS3	No	2	NTRK1, ECSIT
IARS2	NDUFS4	No	1	APP
IARS2	NDUFS8	No	1	ECSIT
NDUFA9	SDHA	No	15	DLD, SDHB, FN1, ICT1, NDUFV2, NDUFS8, NDUFS2, NDUFA2, UQCRFS1, FBXO6, NTRK1, NDUFV1, NDUFS6, NDUFS3, ATP5F1
NDUFA9	NDUFAF5	No	3	NDUFS7, NDUFA10, NDUFS3
NDUFA9	ECHS1	No	1	NTRK1
NDUFA9	NDUFS3	Yes	35	FN1, NDUFS5, NDUFV2, NDUFS8, NDUFB11, NDUFB9, EGFR, NDUFS4, NDUFB1, NDUFS1, ICT1, HTT, NDUFA13, NDUFA5, NDUFS7, NDUFA7, NDUFB7, NDUFV1, NDUFA12, NDUFS2, NDUFA11, UQCRC2, NDUFB8, NDUFS6, GOLT1B, NDUFB10, NDUFB4, TCTN3, ATP1B3, NDUFA2, ND5, NDUFB3, NTRK1, NDUFB5, NDUFV3
NDUFA9	NDUFS4	Yes	30	NDUFS8, NDUFS1, NDUFA8, NDUFS5, VAPA, VDAC2, VDAC3, NDUFV2, NDUFA13, ND5, NDUFS7, NDUFA7, NDUFA12, NDUFV1, COX15, ATP5F1, NDUFS2, NDUFA11, UQCRC2, NDUFB8, NDUFB5, NDUFS3, GOLT1B, NDUFB10, NDUFB4, NDUFA2, NDUFS6, SDHB, VDAC1, NDUFV3
NDUFA9	NDUFS7	Yes	20	NDUFS2, NDUFB10, TIMMDC1, NDUFV2, NDUFS5, NDUFS4, NDUFS8, NDUFA13, NDUFA8, NDUFS7, NDUFA11, NDUFA5, NDUFS6, NDUFS3, NDUFA12, NDUFB5, FBXO6, NDUFV1, NDUFS1, ATP5F1
NDUFA9	NDUFS8	Yes	24	ABCC2, NDUFV2, NDUFA8, NDUFS5, VAPA, VDAC3, NDUFS1, ICT1, NDUFA12, NDUFS7, OPA1, NDUFS6, COX15, TIMMDC1, NDUFS2, NDUFA11, UQCRC2, NDUFS4, NDUFV1, NDUFS3, GOLT1B, TCTN3, AFG3L2, SDHB
NDUFA9	COX15	Yes	4	NDUFS8, NDUFS6, NDUFS4, NDUFA12
SDHA	NDUFAF5	No	1	NDUFS3
SDHA	ECHS1	No	4	NTRK1, HSPA9, NXF1, PPIB
SDHA	NDUFS3	Yes	19	FN1, ICT1, NDUFV2, NDUFS8, CUL3, UQCRQ, NDUFS2, SAMM50, CYC1, ATP1B1, UBC, NDUFA2, NDUFS6, SQSTM1, NTRK1, NXF1, CRY1, NDUFV1, ITGA4
SDHA	NDUFS4	No	12	NDUFS2, ATP5F1, NDUFV2, NDUFS8, CYC1, NDUFA2, MARC1, SDHB, NDUFV1, NDUFS6, NDUFS3, UQCRB
SDHA	NDUFS7	No	9	NDUFS2, FBXO6, NDUFV2, ATP5F1, NDUFS8, DNAJA3, NDUFV1, NDUFS6, NDUFS3
SDHA	NDUFS8	Yes	13	HSPA9, DHODH, CEP128, NDUFV2, UQCRQ, NDUFS2, CYC1, SAMM50, SDHB, NDUFV1, ICT1, NDUFS6, NDUFS3
SDHA	COX15	No	3	NDUFS8, NDUFS6, CYC1
NDUFAF5	NDUFS3	Yes	2	NDUFS7, NDUFAF3
NDUFAF5	NDUFS4	No	3	NDUFS7, NDUFAF3, NDUFS3
NDUFAF5	NDUFS7	Yes	3	NDUFS7, NDUFAF3, NDUFS3
NDUFAF5	NDUFS8	No	3	NDUFS7, NDUFAF3, NDUFS3
ECHS1	NDUFS3	No	4	NTRK1, NXF1, MOV10, CUL7
ECHS1	NDUFS4	No	2	ALDOA, COX4I1
ECHS1	NDUFS8	No	1	HSPA9
NDUFS3	NDUFS4	Yes	27	ND1, NDUFS5, NDUFV2, NDUFS8, CYC1, NDUFAF3, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFA12, NDUFV1, ND4, NDUFS2, NDUFA11, UQCRC2, NDUFB8, NDUFS6, GOLT1B, NDUFB10, NDUFA9, PARK2, NDUFA2, ND5, NDUFB5, NDUFV3
NDUFS3	NDUFS7	Yes	20	NDUFA11, NDUFB5, NDUFS2, NDUFB10, NDUFS1, NDUFV2, NDUFAF4, NDUFS4, NDUFA12, NDUFA13, NDUFS8, NDUFS7, ACAD9, NDUFA5, NDUFA9, NDUFAF3, NDUFAF5, NDUFS5, NDUFV1, NDUFS6
NDUFS3	NDUFS8	Yes	23	NDUFS5, NDUFV2, UQCRQ, CYC1, NDUFS7, NDUFAF3, NDUFS1, ICT1, SAMM50, NDUFA12, NDUFS6, ECSIT, TMEM17, NDUFS2, NDUFA11, SDHA, UQCRC2, NDUFS4, NDUFV1, GOLT1B, TCTN3, NDUFA9, SURF1
NDUFS3	COX15	No	7	NDUFS8, NDUFA9, CYC1, SURF1, NDUFA12, NDUFS4, NDUFS6
NDUFS4	NDUFS7	Yes	18	NDUFS2, NDUFB10, NDUFV2, ATP5F1, NDUFA12, NDUFA9, NDUFA13, NDUFS8, NDUFS7, NDUFA11, NDUFA8, NDUFS6, NDUFS3, NDUFAF3, NDUFS5, NDUFB5, NDUFV1, NDUFS1
NDUFS4	NDUFS8	Yes	20	SDHB, GOLT1B, COX15, NDUFV2, NDUFS1, NDUFS5, UQCRC2, NDUFAF3, NDUFA9, NDUFS2, CYC1, NDUFA11, NDUFA8, NDUFS7, NDUFS3, NDUFA12, VDAC3, NDUFV1, NDUFS6, VAPA
NDUFS4	COX15	Yes	6	NDUFS8, NDUFA12, NDUFA9, CYC1, MRPL15, NDUFS6
NDUFS7	NDUFS8	Yes	17	NDUFS2, TIMMDC1, NDUFV2, NDUFA12, NDUFS4, NDUFAF3, NDUFA9, RHOT2, NDUFA11, NDUFA8, NDUFS7, NDUFS3, MPV17, NDUFS5, NDUFV1, NDUFS6, NDUFS1
NDUFS7	COX15	No	5	NDUFS8, NDUFS6, NDUFA9, NDUFS4, NDUFA12
NDUFS8	COX15	Yes	6	NDUFA9, CYC1, SURF1, NDUFA12, NDUFS4, NDUFS6

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from BIOGRID - genetic

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
IARS2	NDUFA9	No	1	KRAS

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from STRING

Gene1	Gene2	Direct Interaction	Interaction mode	Number of shared interactors	Shared genes in interaction
MT-CO3	NDUFV1	No	-	1	NDUFA4
MT-CO3	MT-ND3	No	-	1	NDUFA4
MT-CO3	MT-ND5	No	-	1	NDUFA4
MT-CO3	BCS1L	Yes	binding	8	MT-CO1, MT-CYB, NDUFA4, MT-CO2, COX4I2, UQCRC2, UQCRFS1, UQCRB
MT-CO3	NDUFA10	No	-	1	NDUFA4
MT-CO3	NDUFA12	No	-	1	NDUFA4
MT-CO3	SURF1	No	-	3	MT-CO1, COX5A, MT-CO2
MT-CO3	MT-ATP6	Yes	binding	2	MT-CO1, OXA1L
MT-CO3	NDUFA2	No	-	1	NDUFA4
MT-CO3	NDUFA9	No	-	1	NDUFA4
MT-CO3	COX10	No	-	1	MT-CO1
MT-CO3	SDHA	No	-	1	COX4I1
MT-CO3	NDUFS3	No	-	1	NDUFA4
MT-CO3	NDUFS4	No	-	1	NDUFA4
MT-CO3	NDUFS7	No	-	1	NDUFA4
MT-CO3	NDUFS8	No	-	1	NDUFA4
NDUFV1	MT-ND3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	MT-ND5	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	BCS1L	No	-	1	NDUFA4
NDUFV1	NDUFA10	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFA12	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFA2	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFA9	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFS3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFV1	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFS6, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	MT-ND5	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	BCS1L	No	-	1	NDUFA4
MT-ND3	NDUFA10	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFA12	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFA2	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFA9	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFS3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND3	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	BCS1L	No	-	1	NDUFA4
MT-ND5	NDUFA10	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFA12	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFA2	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFA9	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFS3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
MT-ND5	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
BCS1L	FOXRED1	No	-	1	UBC
BCS1L	NDUFA10	No	-	1	NDUFA4
BCS1L	NDUFA12	No	-	2	UBC, NDUFA4
BCS1L	SURF1	No	-	2	MT-CO1, MT-CO2
BCS1L	MT-ATP6	No	-	2	MT-CO1, MT-CO3
BCS1L	NDUFA2	No	-	1	NDUFA4
BCS1L	IARS2	No	-	1	UBC
BCS1L	NDUFA9	No	-	2	UBC, NDUFA4
BCS1L	COX10	No	-	1	MT-CO1
BCS1L	SDHA	No	-	1	UBC
BCS1L	ECHS1	No	-	1	UBC
BCS1L	NDUFS3	No	-	2	UBC, NDUFA4
BCS1L	NDUFS4	No	-	1	NDUFA4
BCS1L	NDUFS7	No	-	2	UBC, NDUFA4
BCS1L	NDUFS8	No	-	1	NDUFA4
FOXRED1	NDUFA12	No	-	1	UBC
FOXRED1	IARS2	No	-	1	UBC
FOXRED1	NDUFA9	No	-	1	UBC
FOXRED1	SDHA	No	-	1	UBC
FOXRED1	ECHS1	No	-	1	UBC
FOXRED1	NDUFS3	No	-	1	UBC
FOXRED1	NDUFS7	No	-	1	UBC
NDUFA10	NDUFA12	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFA2	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFA9	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFS3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA10	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFS3, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	NDUFA2	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	IARS2	No	-	1	UBC
NDUFA12	NDUFA9	Yes	binding	44	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, MT-ND5, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	SDHA	No	-	1	UBC
NDUFA12	ECHS1	No	-	1	UBC
NDUFA12	NDUFS3	Yes	binding	45	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFC2-KCTD14, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	NDUFS7	Yes	binding	44	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA12	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
SURF1	MT-ATP6	No	-	1	MT-CO1
SURF1	COX10	No	-	1	MT-CO1
MT-ATP6	COX10	No	-	1	MT-CO1
NDUFA2	NDUFA9	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA2	NDUFS3	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA2	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA2	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA2	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NARS2	IARS2	Yes	binding	3	EPRS, MARS2, MARS
IARS2	NDUFA9	No	-	1	UBC
IARS2	SDHA	No	-	1	UBC
IARS2	ECHS1	No	-	1	UBC
IARS2	NDUFS3	No	-	1	UBC
IARS2	NDUFS7	No	-	1	UBC
NDUFA9	SDHA	No	-	1	UBC
NDUFA9	ECHS1	No	-	1	UBC
NDUFA9	NDUFS3	Yes	binding	44	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA9	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA9	NDUFS7	Yes	binding	44	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFA9	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
COX10	COX15	Yes	binding	1	COX11
SDHA	ECHS1	No	-	1	UBC
SDHA	NDUFS3	No	-	1	UBC
SDHA	NDUFS7	No	-	1	UBC
ECHS1	NDUFS3	No	-	1	UBC
ECHS1	NDUFS7	No	-	1	UBC
NDUFS3	NDUFS4	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFS3	NDUFS7	Yes	binding	44	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, UBC, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFS3	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFS4	NDUFS7	Yes	binding	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFS4	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2
NDUFS7	NDUFS8	Yes	binding	43	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA9, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFV1, NDUFA10, NDUFS2, NDUFB10, NDUFB2, MT-ND5, NDUFS4, MT-ND4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA4, NDUFV3, NDUFC2

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CORUM

Gene1	Gene2	Direct Interaction	Complexes	Number of shared interactors	Shared genes in interaction
NDUFV1	MT-ND3	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	MT-ND5	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFA10	Yes	Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFA12	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFA2	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFA9	Yes	Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFV1	NDUFS3	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFS4	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFS7	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFV1	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	MT-ND5	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFV1, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFA10	Yes	Respiratory chain complex I (gamma subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFA12	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFA2	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFA9	Yes	Respiratory chain complex I (gamma subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFV3, NDUFC2
MT-ND3	NDUFS3	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, MT-ND2, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, NDUFAF1, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFS4	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFS7	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND3	NDUFS8	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFA10	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFS3, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFA12	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFA2	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFA9	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
MT-ND5	NDUFS3	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFS4	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFS7	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
MT-ND5	NDUFS8	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, NDUFC1, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFA12	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFA2	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFA9	Yes	Respiratory chain complex I (gamma subunit) mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA10	NDUFS3	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFS4	Yes	Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFS7	Yes	Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, NDUFB9, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFA3, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFB7, NDUFA8, NDUFV1, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA6, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFS4, NDUFA4, MT-ND2, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA10	NDUFS8	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFS3, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA12	NDUFA2	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA12	NDUFA9	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA12	NDUFS3	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA12	NDUFS4	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA12	NDUFS7	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA12	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA2	NDUFA9	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (intermediate V/380kD and VI/480kD), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA2	NDUFS3	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (intermediate V/380kD and VI/480kD), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFS7, NDUFA7, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA2	NDUFS4	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA2	NDUFS7	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA2	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFA9	NDUFS3	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (intermediate V/380kD and VI/480kD), mitochondrial;Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial;Respiratory chain complex I (intermediate I/200kD and III/250kD), mitochondrial;Respiratory chain complex I (intermediate IV/310kD), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA9	NDUFS4	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA9	NDUFS7	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFA7, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFA9	NDUFS8	Yes	Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFV3, NDUFC2
NDUFS3	NDUFS4	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFS3	NDUFS7	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (early intermediate NDUFAF1 assembly), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	43	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFB4, NDUFA7, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFAF1, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFS3	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFS4	NDUFS7	Yes	Respiratory chain complex I (intermediate VII/650kD), mitochondrial;Respiratory chain complex I (intermediate II/230kD), mitochondrial;Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (incomplete intermediate), mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFS8, NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFS4	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFS7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2
NDUFS7	NDUFS8	Yes	Respiratory chain complex I (lambda subunit) mitochondrial;Respiratory chain complex I (holoenzyme), mitochondrial	42	NDUFV2, MT-ND1, MT-ND2, NDUFS5, NDUFA1, MT-ND4L, NDUFB1, NDUFS1, NDUFA13, NDUFA7, NDUFB4, NDUFS3, NDUFB7, NDUFA8, NDUFA6, NDUFA12, MT-ND3, NDUFA5, NDUFAB1, NDUFA11, NDUFC1, MT-ND6, NDUFB11, NDUFB6, NDUFB8, NDUFA3, NDUFA10, NDUFS2, NDUFB10, MT-ND5, NDUFB2, NDUFV1, NDUFS4, NDUFA4, NDUFB9, NDUFA2, NDUFS6, NDUFB3, NDUFB5, NDUFA9, NDUFV3, NDUFC2

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from CENSUS

Gene1	Gene2	Direct Interaction	Number of shared interactors	Shared genes in interaction
NDUFAF2	NDUFA2	No	1	CDV3
NDUFV1	MT-ND5	Yes	7	NDUFS2, NDUFV2, NDUFS1, NDUFS8, NDUFS7, MT-ND1, NDUFS3
NDUFV1	NDUFA10	No	1	NDUFV2
NDUFV1	NDUFA12	No	2	NDUFA9, NDUFS1
NDUFV1	SURF1	No	4	NDUFS3, NDUFS8, ABCD3, NDUFV2
NDUFV1	NDUFA2	No	2	ILF3, CPT1A
NDUFV1	IARS2	No	1	ILF3
NDUFV1	NDUFA9	Yes	1	NDUFS1
NDUFV1	SDHA	Yes	4	NDUFS3, NDUFS8, NDUFS2, NDUFV2
NDUFV1	NDUFS3	Yes	7	NDUFS2, MT-ND5, NDUFV2, NDUFS8, NDUFS7, MT-ND1, SDHA
NDUFV1	NDUFS4	No	2	ABCD3, NDUFS7
NDUFV1	NDUFS7	Yes	8	NDUFS2, NDUFB10, NDUFV2, MT-ND5, NDUFS8, MT-ND1, NDUFS3, NDUFS1
NDUFV1	NDUFS8	Yes	8	NDUFS2, NDUFV2, NDUFS1, MT-ND5, MT-ND1, NDUFS7, NDUFS3, SDHA
NDUFV1	COX15	No	2	NDUFS8, NDUFA9
MT-ND5	NDUFA10	No	3	ABCC2, MPV17, NDUFV2
MT-ND5	NDUFA12	No	2	MPV17, NDUFS1
MT-ND5	SURF1	No	4	ABCC1, NDUFS8, NDUFS3, NDUFV2
MT-ND5	NDUFA2	No	2	DHX30, ABCC2
MT-ND5	NDUFA9	No	4	DLD, NDUFV1, ABCC2, NDUFS1
MT-ND5	SDHA	No	6	NDUFS8, NDUFV2, NDUFS2, UQCRB, NDUFV1, NDUFS3
MT-ND5	NDUFS3	Yes	7	NDUFS2, NDUFV2, NDUFS8, NDUFS7, NDUFA5, MT-ND1, NDUFV1
MT-ND5	NDUFS4	No	3	DLAT, UQCRB, NDUFS7
MT-ND5	NDUFS7	Yes	8	NDUFS2, NDUFS1, NDUFV2, NDUFS8, MT-ND1, MPV17, NDUFV1, NDUFS3
MT-ND5	NDUFS8	Yes	9	NDUFS2, NDUFS1, NDUFV2, MT-ND1, NDUFS7, MPV17, NDUFV1, ABCC2, NDUFS3
MT-ND5	COX15	No	1	NDUFS8
BCS1L	SDHA	No	1	UQCRFS1
NDUFA10	NDUFA12	No	1	MPV17
NDUFA10	SURF1	No	1	NDUFV2
NDUFA10	NDUFA2	No	1	ABCC2
NDUFA10	NDUFA9	No	2	ABCC2, SDHB
NDUFA10	SDHA	No	2	SDHB, NDUFV2
NDUFA10	NDUFS3	No	1	NDUFV2
NDUFA10	NDUFS7	No	2	MPV17, NDUFV2
NDUFA10	NDUFS8	No	3	ABCC2, MPV17, NDUFV2
NDUFA12	SURF1	Yes	2	COX15, CYC1
NDUFA12	MT-ATP6	Yes	0
NDUFA12	NDUFA2	Yes	2	ATP5B, NDUFB9
NDUFA12	NDUFA9	Yes	2	COX15, NDUFS1
NDUFA12	NDUFS3	No	1	SURF1
NDUFA12	NDUFS4	Yes	3	COX15, MRPL15, CYC1
NDUFA12	NDUFS7	No	3	NDUFS4, MPV17, NDUFS1
NDUFA12	NDUFS8	No	5	CYC1, SURF1, COX15, MPV17, NDUFS1
NDUFA12	COX15	Yes	5	SURF1, MRPL15, NDUFA9, NDUFS4, CYC1
SURF1	MT-ATP6	No	1	NDUFA12
SURF1	NDUFA2	No	1	NDUFA12
SURF1	NDUFA9	No	3	NDUFB8, COX15, NDUFA12
SURF1	SDHA	No	4	NDUFS8, SAMM50, NDUFS3, NDUFV2
SURF1	NDUFS3	Yes	3	NDUFS8, SAMM50, NDUFV2
SURF1	NDUFS4	No	5	NDUFAF3, ABCD3, COX15, NDUFA12, CYC1
SURF1	NDUFS7	No	3	NDUFS8, NDUFS3, NDUFV2
SURF1	NDUFS8	Yes	7	COX15, NDUFV2, SAMM50, MT-CO2, CYC1, NDUFAF3, NDUFS3
SURF1	COX15	Yes	4	NDUFS8, MT-CO2, CYC1, NDUFA12
MT-ATP6	NDUFA2	No	1	NDUFA12
MT-ATP6	NDUFA9	No	1	NDUFA12
MT-ATP6	NDUFS4	No	1	NDUFA12
MT-ATP6	COX15	No	1	NDUFA12
NDUFA2	IARS2	No	1	ILF3
NDUFA2	NDUFA9	No	2	NDUFA12, ABCC2
NDUFA2	SDHA	No	1	NDUFS6
NDUFA2	NDUFS4	No	2	NDUFS6, NDUFA12
NDUFA2	NDUFS7	No	1	NDUFS6
NDUFA2	NDUFS8	No	2	NDUFS6, ABCC2
NDUFA2	COX15	No	3	NDUFS6, LAMTOR3, NDUFA12
NDUFA9	SDHA	No	2	NDUFV1, SDHB
NDUFA9	NDUFS3	No	1	NDUFV1
NDUFA9	NDUFS4	No	2	COX15, NDUFA12
NDUFA9	NDUFS7	No	2	NDUFV1, NDUFS1
NDUFA9	NDUFS8	No	5	NDUFV1, OPA1, COX15, ABCC2, NDUFS1
NDUFA9	COX15	Yes	1	NDUFA12
SDHA	NDUFS3	Yes	5	NDUFS2, NDUFS8, SAMM50, NDUFV1, NDUFV2
SDHA	NDUFS4	No	3	UQCRB, MARC1, NDUFS6
SDHA	NDUFS7	No	7	NDUFS8, ATP5F1, NDUFV2, NDUFS2, NDUFV1, NDUFS6, NDUFS3
SDHA	NDUFS8	Yes	7	NDUFS2, NDUFV2, DHODH, SAMM50, NDUFV1, NDUFS6, NDUFS3
SDHA	COX15	No	2	NDUFS8, NDUFS6
NDUFS3	NDUFS4	No	1	NDUFS7
NDUFS3	NDUFS7	Yes	6	NDUFS2, MT-ND5, NDUFV2, NDUFS8, MT-ND1, NDUFV1
NDUFS3	NDUFS8	Yes	9	NDUFS2, MT-ND5, NDUFV2, SAMM50, SURF1, NDUFS7, MT-ND1, NDUFV1, SDHA
NDUFS3	COX15	No	2	NDUFS8, SURF1
NDUFS4	NDUFS7	Yes	2	NDUFB5, NDUFS6
NDUFS4	NDUFS8	No	5	NDUFS6, NDUFS7, COX15, NDUFAF3, CYC1
NDUFS4	COX15	Yes	4	NDUFS6, MRPL15, CYC1, NDUFA12
NDUFS7	NDUFS8	Yes	10	NDUFS2, NDUFV2, MT-ND5, RHOT2, MT-ND1, NDUFS3, MPV17, NDUFV1, NDUFS6, NDUFS1
NDUFS7	COX15	No	3	NDUFS8, NDUFS6, NDUFS4
NDUFS8	COX15	Yes	4	SURF1, NDUFS6, MT-CO2, CYC1

Direct interactions graph
Interactions graph (direct and indirect interactions, when direct are not available)

Interactions from PDB

Interactions from manually curated literature

KEGG pathways annotation: shared terms / NET-GE enrichment

Shared terms

KEGG term	KEGG term ID	IC	Number of genes with the same term	Genes
Metabolic pathways	hsa01100	2.49	18	NDUFS8, ECHS1, MT-CO3, MT-ND3, NDUFA9, MT-ND5, NDUFA10, MT-ATP6, POLG, NDUFA2, NDUFS7, NDUFS3, NDUFA12, COX15, NDUFV1, NDUFS4, COX10, SDHA
Oxidative phosphorylation	hsa00190	5.69	16	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, MT-CO3, MT-ATP6, SDHA, NDUFA2, NDUFS7, NDUFA12, NDUFS3, NDUFV1, COX10, NDUFS4, NDUFA10
Parkinson's disease	hsa05012	5.59	14	NDUFS8, MT-ND5, MT-ND3, NDUFA9, MT-CO3, NDUFA10, SDHA, NDUFA2, NDUFS7, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, NDUFS3
Huntington's disease	hsa05016	5.17	12	NDUFS8, MT-CO3, NDUFA9, MT-ATP6, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3, SDHA
Alzheimer's disease	hsa05010	5.34	12	NDUFS8, MT-CO3, NDUFA9, NDUFA10, MT-ATP6, NDUFS7, NDUFA2, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
Non-alcoholic fatty liver disease (NAFLD)	hsa04932	5.51	11	NDUFS8, MT-CO3, NDUFA9, SDHA, NDUFA2, NDUFS7, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
Aminoacyl-tRNA biosynthesis	hsa00970	7.31	3	MTFMT, IARS2, NARS2
Carbon metabolism	hsa01200	6.03	2	ECHS1, SDHA
Porphyrin and chlorophyll metabolism	hsa00860	7.41	2	COX15, COX10

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
Neurodegenerative diseases	NEW	4.27	0.0	NDUFS8, MT-CO3, MT-ND5, NDUFA9, NDUFA2, SDHA, BCS1L, NDUFS7, MT-ND3, NDUFA10, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, NDUFS3
Global and overview maps	NEW	2.47	0.0	NDUFS8, ECHS1, MT-ND3, MT-CO3, NDUFA10, NDUFA9, MT-ND5, NARS2, NDUFA2, POLG, BCS1L, NDUFS7, SURF1, SDHA, NDUFA12, MT-ATP6, NDUFS3, COX15, NDUFV1, NDUFS4, COX10
Endocrine and metabolic diseases	NEW	4.75	0.0	NDUFS8, MT-ND3, MT-CO3, NDUFA9, NDUFA10, NDUFA2, NDUFS7, BCS1L, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
Metabolism	NEW	2.06	0.0	NDUFS8, NDUFA10, POLG, COX15, MTFMT, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFV1, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
Oxidative phosphorylation (hsa00190)	-	5.69	0.0	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, MT-CO3, NDUFA10, NDUFS7, NDUFA2, NDUFS3, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, COX10, SDHA
Aminoacyl-tRNA biosynthesis (hsa00970)	-	7.31	0.001	MTFMT, IARS2, NARS2, POLG
Metabolic pathways (hsa01100)	-	2.49	0.0	NDUFS8, ECHS1, MT-ND3, MT-ND5, NDUFA10, MT-CO3, NDUFA9, NARS2, NDUFA2, POLG, BCS1L, NDUFS7, SURF1, COX10, NDUFA12, MT-ATP6, COX15, NDUFV1, NDUFS4, NDUFS3, SDHA
Energy metabolism	NEW	5.42	0.0	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA10, NDUFA9, MT-CO3, BCS1L, NDUFS7, NDUFA2, NDUFS3, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, COX10, SDHA
Parkinson's disease (hsa05012)	-	5.59	0.0	NDUFS8, MT-CO3, MT-ND5, NDUFA9, MT-ATP6, SDHA, NDUFA2, NDUFS7, MT-ND3, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
Huntington's disease (hsa05016)	-	5.17	0.0	NDUFS8, MT-CO3, NDUFA9, MT-ATP6, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3, SDHA
Alzheimer's disease (hsa05010)	-	5.34	0.0	NDUFS8, MT-CO3, NDUFA9, NDUFA10, MT-ATP6, NDUFS7, NDUFA2, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
Non-alcoholic fatty liver disease (NAFLD) (hsa04932)	-	5.51	0.0	NDUFS8, MT-CO3, NDUFA9, NDUFA2, NDUFS7, BCS1L, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3, SDHA

REACTOME pathways annotation: shared terms / NET-GE enrichment

Shared terms

REACTOME term	REACTOME term ID	IC	Number of genes with the same term	Genes
Metabolism	R-HSA-1430728	2.34	21	MT-ATP6, NDUFS8, ECHS1, MT-ND3, MT-CO3, NDUFS4, NDUFA9, MT-ND5, NDUFA10, SURF1, NDUFS7, NDUFAF2, NDUFA2, SDHA, NDUFA12, NDUFS3, NDUFAF6, COX15, NDUFV1, NDUFAF5, COX10
The citric acid (TCA) cycle and respiratory electron transport	R-HSA-1428517	5.71	18	NDUFS8, MT-ND3, MT-ND5, NDUFS4, NDUFA9, MT-CO3, NDUFA10, SDHA, NDUFAF6, NDUFA2, SURF1, NDUFS7, NDUFA12, MT-ATP6, NDUFAF2, NDUFV1, NDUFAF5, NDUFS3
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	R-HSA-163200	6.12	18	NDUFS8, MT-ND3, MT-CO3, NDUFS4, NDUFA9, MT-ND5, NDUFA10, SURF1, NDUFS7, NDUFAF2, NDUFA2, SDHA, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3
Respiratory electron transport	R-HSA-611105	6.44	17	NDUFS8, MT-CO3, MT-ND5, NDUFS4, NDUFA9, SURF1, NDUFS7, NDUFAF2, NDUFA2, MT-ND3, NDUFA10, NDUFA12, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3, SDHA
Gene Expression	R-HSA-74160	2.72	4	SURF1, NARS2, IARS2, MT-CO3
Transcriptional Regulation by TP53	R-HSA-3700989	6.73	2	SURF1, MT-CO3
Mitochondrial tRNA aminoacylation	R-HSA-379726	8.59	2	IARS2, NARS2
tRNA Aminoacylation	R-HSA-379724	7.59	2	IARS2, NARS2
Generic Transcription Pathway	R-HSA-212436	3.86	2	SURF1, MT-CO3
Heme biosynthesis	R-HSA-189451	9.52	2	COX15, COX10
Metabolism of porphyrins	R-HSA-189445	8.89	2	COX15, COX10
TP53 Regulates Metabolic Genes	R-HSA-5628897	6.73	2	SURF1, MT-CO3

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
Respiratory electron transport (R-HSA-611105)	-	6.44	0.0	NDUFS8, MT-CO3, MT-ND5, NDUFS4, NDUFA9, SURF1, NDUFS7, NDUFAF2, NDUFA2, MT-ND3, NDUFA10, NDUFA12, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3, SDHA
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (R-HSA-163200)	-	6.12	0.0	NDUFS8, MT-ND3, MT-CO3, NDUFS4, NDUFA9, MT-ND5, NDUFA10, SURF1, NDUFS7, NDUFAF2, NDUFA2, SDHA, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3
The citric acid (TCA) cycle and respiratory electron transport (R-HSA-1428517)	-	5.71	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFS4, NDUFA9, MT-CO3, NDUFA10, SDHA, NDUFAF6, NDUFA2, SURF1, NDUFS7, NDUFA12, MT-ATP6, NDUFAF2, NDUFV1, NDUFAF5, NDUFS3
Heme biosynthesis (R-HSA-189451)	-	9.52	0.015	COX15, COX10
Metabolism (R-HSA-1430728)	-	2.34	0.0	NDUFS8, NDUFA10, SDHA, NDUFAF6, COX15, MT-ND3, SURF1, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, BCS1L, NDUFS4, NDUFV1, NDUFS3, MT-ND5, NDUFA9, NDUFA2
Metabolism of porphyrins (R-HSA-189445)	-	8.89	0.036	COX15, COX10

GO - molecular function annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
catalytic activity (GO:0003824)	1.05	26	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, NDUFA2
oxidoreductase activity (GO:0016491)	3.12	18	NDUFS8, COX15, NDUFA12, MT-CO3, NDUFA9, MT-ND5, NDUFA10, SURF1, NDUFS7, NDUFA2, MT-ND3, NDUFS3, FOXRED1, NDUFAF2, NDUFV1, NDUFS4, COX10, SDHA
binding (GO:0005488)	0.18	14	NDUFS8, ECHS1, MT-CO3, MT-ND3, NDUFA9, NARS2, BCS1L, POLG, IARS2, SURF1, NDUFS7, NDUFV1, NDUFS3, SDHA
oxidoreductase activity, acting on NAD(P)H (GO:0016651)	5.13	13	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (GO:0016655)	5.66	12	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
NADH dehydrogenase activity (GO:0003954)	5.93	12	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
NADH dehydrogenase (ubiquinone) activity (GO:0008137)	5.93	12	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
NADH dehydrogenase (quinone) activity (GO:0050136)	5.93	12	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
protein binding (GO:0005515)	0.46	10	ECHS1, MT-CO3, MT-ND3, NDUFA9, SURF1, POLG, BCS1L, NDUFS7, SDHA, NDUFS3
electron carrier activity (GO:0009055)	4.97	7	COX15, MT-CO3, SURF1, NDUFS3, NDUFA12, NDUFAF2, COX10
organic cyclic compound binding (GO:0097159)	1.05	6	NARS2, BCS1L, POLG, IARS2, SDHA, NDUFV1
heterocyclic compound binding (GO:1901363)	1.06	6	NARS2, BCS1L, POLG, IARS2, SDHA, NDUFV1
substrate-specific transmembrane transporter activity (GO:0022891)	2.9	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
inorganic cation transmembrane transporter activity (GO:0022890)	3.49	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
substrate-specific transporter activity (GO:0022892)	2.72	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
transporter activity (GO:0005215)	2.57	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
cation transmembrane transporter activity (GO:0008324)	3.32	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
monovalent inorganic cation transmembrane transporter activity (GO:0015077)	3.87	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
nucleotide binding (GO:0000166)	1.96	5	BCS1L, IARS2, NARS2, NDUFV1, SDHA
ion transmembrane transporter activity (GO:0015075)	3.04	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
transmembrane transporter activity (GO:0022857)	2.82	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
transferase activity (GO:0016740)	1.95	5	MTFMT, NDUFAF6, NDUFAF5, COX10, POLG
small molecule binding (GO:0036094)	1.89	5	BCS1L, IARS2, NARS2, NDUFV1, SDHA
hydrogen ion transmembrane transporter activity (GO:0015078)	5.01	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
nucleoside phosphate binding (GO:1901265)	1.96	5	BCS1L, NDUFV1, NARS2, IARS2, SDHA
cytochrome-c oxidase activity (GO:0004129)	6.34	4	SURF1, COX15, MT-CO3, COX10
carbohydrate derivative binding (GO:0097367)	2.03	4	BCS1L, NDUFV1, NARS2, IARS2
oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor (GO:0016676)	6.34	4	SURF1, COX15, MT-CO3, COX10
heme-copper terminal oxidase activity (GO:0015002)	6.34	4	SURF1, COX15, MT-CO3, COX10
oxidoreductase activity, acting on a heme group of donors (GO:0016675)	6.3	4	SURF1, COX15, MT-CO3, COX10
cofactor binding (GO:0048037)	4.16	4	NDUFV1, NDUFA9, NDUFS7, SDHA
ribonucleotide binding (GO:0032553)	2.19	4	BCS1L, IARS2, NARS2, NDUFV1
hydrolase activity (GO:0016787)	1.9	3	IARS2, MT-ATP6, POLG
4 iron, 4 sulfur cluster binding (GO:0051539)	6.0	3	NDUFS8, NDUFV1, NDUFS7
cation binding (GO:0043169)	1.4	3	NDUFS8, NDUFV1, NDUFS7
purine ribonucleoside triphosphate binding (GO:0035639)	2.22	3	IARS2, NARS2, BCS1L
metal cluster binding (GO:0051540)	5.55	3	NDUFS8, NDUFV1, NDUFS7
iron-sulfur cluster binding (GO:0051536)	5.55	3	NDUFS8, NDUFV1, NDUFS7
adenyl nucleotide binding (GO:0030554)	2.4	3	IARS2, NARS2, BCS1L
ion binding (GO:0043167)	1.36	3	NDUFS8, NDUFV1, NDUFS7
coenzyme binding (GO:0050662)	4.53	3	NDUFV1, NDUFA9, SDHA
adenyl ribonucleotide binding (GO:0032559)	2.41	3	IARS2, NARS2, BCS1L
purine nucleoside binding (GO:0001883)	2.22	3	IARS2, NARS2, BCS1L
ribonucleoside binding (GO:0032549)	2.22	3	IARS2, NARS2, BCS1L
purine ribonucleotide binding (GO:0032555)	2.2	3	IARS2, NARS2, BCS1L
purine nucleotide binding (GO:0017076)	2.19	3	IARS2, NARS2, BCS1L
metal ion binding (GO:0046872)	1.41	3	NDUFS8, NDUFV1, NDUFS7
purine ribonucleoside binding (GO:0032550)	2.22	3	IARS2, NARS2, BCS1L
ATP binding (GO:0005524)	2.43	3	IARS2, NARS2, BCS1L
nucleoside binding (GO:0001882)	2.21	3	IARS2, NARS2, BCS1L
aminoacyl-tRNA ligase activity (GO:0004812)	5.93	2	IARS2, NARS2
nucleic acid binding (GO:0003676)	1.44	2	NARS2, POLG
oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627)	5.66	2	COX15, SDHA
enzyme binding (GO:0019899)	2.27	2	NDUFS7, POLG
transferase activity, transferring one-carbon groups (GO:0016741)	4.3	2	MTFMT, NDUFAF5
macromolecular complex binding (GO:0044877)	2.61	2	NDUFA9, POLG
hydrolase activity, acting on ester bonds (GO:0016788)	3.1	2	IARS2, POLG
protease binding (GO:0002020)	5.08	2	NDUFS7, POLG
ligase activity (GO:0016874)	3.72	2	IARS2, NARS2
ligase activity, forming carbon-oxygen bonds (GO:0016875)	5.93	2	IARS2, NARS2
ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876)	5.93	2	IARS2, NARS2

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
cytochrome-c oxidase activity (GO:0004129)	-	6.34	0.003	SURF1, COX15, MT-CO3
NADH dehydrogenase (quinone) activity (GO:0050136)	-	5.93	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
4 iron, 4 sulfur cluster binding (GO:0051539)	-	6.0	0.003	NDUFS8, NDUFV1, NDUFS7
prenyltransferase activity (GO:0004659)	NEW	6.91	0.048	COX15, COX10
catalytic activity (GO:0003824)	-	1.05	0.0	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, SURF1
NADH dehydrogenase (ubiquinone) activity (GO:0008137)	-	5.93	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
iron-sulfur cluster binding (GO:0051536)	-	5.55	0.014	NDUFS8, NDUFV1, NDUFS7
hydrogen ion transmembrane transporter activity (GO:0015078)	-	5.01	0.014	SURF1, COX15, MT-ATP6, MT-CO3
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor (GO:0016655)	-	5.66	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
farnesyltranstransferase activity (GO:0004311)	NEW	8.35	0.004	COX15, COX10
oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor (GO:0016676)	-	6.34	0.003	SURF1, COX15, MT-CO3
oxidoreductase activity, acting on NAD(P)H (GO:0016651)	-	5.13	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
oxidoreductase activity, acting on a heme group of donors (GO:0016675)	-	6.3	0.003	SURF1, COX15, MT-CO3
metal cluster binding (GO:0051540)	-	5.55	0.014	NDUFS8, NDUFV1, NDUFS7
electron carrier activity (GO:0009055)	-	4.97	0.0	COX15, MT-CO3, SURF1, BCS1L, NDUFA12, NDUFS3
NADH dehydrogenase activity (GO:0003954)	-	5.93	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3
heme-copper terminal oxidase activity (GO:0015002)	-	6.34	0.003	SURF1, COX15, MT-CO3
oxidoreductase activity (GO:0016491)	-	3.12	0.0	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS8, NDUFA9, NDUFA10, NDUFA2, NDUFS7, MT-ND3, BCS1L, SURF1, SDHA, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, NDUFS3

GO - biological process annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
cellular process (GO:0009987)	0.26	27	NDUFS8, FOXRED1, POLG, NDUFAF6, COX15, NDUFS3, MTFMT, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-ND3, IARS2, SDHA, NDUFS4, NDUFV1, COX10, MT-ND5, NDUFA9, BCS1L, SURF1
metabolic process (GO:0008152)	0.58	26	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, NDUFA2
cellular metabolic process (GO:0044237)	0.69	23	NDUFS8, POLG, COX15, MTFMT, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, SDHA, NDUFS4, COX10, NDUFS3, MT-ND5, NDUFA9, SURF1
single-organism process (GO:0044699)	0.48	23	NDUFS8, NDUFA10, FOXRED1, POLG, COX15, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, SDHA, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
single-organism metabolic process (GO:0044710)	1.63	22	NDUFS8, NDUFA10, FOXRED1, SDHA, COX15, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
single-organism cellular process (GO:0044763)	0.65	22	NDUFS8, NDUFA10, POLG, COX15, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, SDHA, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
cellular component assembly (GO:0022607)	2.14	20	NDUFS8, COX15, MT-CO3, MT-ND3, NDUFA12, NDUFS4, NDUFA9, MT-ND5, NDUFA10, NDUFA2, NDUFS7, NDUFAF2, BCS1L, SURF1, NDUFS3, FOXRED1, NDUFAF6, NDUFV1, NDUFAF5, COX10
protein complex subunit organization (GO:0071822)	2.6	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, MT-ND3, NDUFAF6, BCS1L, SURF1, NDUFA10, NDUFA12, NDUFS3, NDUFAF2, NDUFV1, NDUFAF5, COX10
macromolecular complex subunit organization (GO:0043933)	2.14	20	NDUFS8, COX15, NDUFA12, MT-ND3, NDUFS4, MT-CO3, NDUFA9, MT-ND5, NDUFA10, NDUFA2, NDUFS7, NDUFAF2, BCS1L, SURF1, NDUFS3, FOXRED1, NDUFAF6, NDUFV1, NDUFAF5, COX10
protein complex assembly (GO:0006461)	2.78	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, MT-ND3, NDUFAF6, BCS1L, SURF1, NDUFA10, NDUFA12, NDUFS3, NDUFAF2, NDUFV1, NDUFAF5, COX10
cellular component organization (GO:0016043)	1.24	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, MT-ND3, NDUFAF6, BCS1L, SURF1, NDUFA10, NDUFA12, NDUFS3, NDUFAF2, NDUFV1, NDUFAF5, COX10
macromolecular complex assembly (GO:0065003)	2.55	20	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA12, NDUFS4, NDUFA9, MT-CO3, BCS1L, NDUFS7, NDUFAF2, NDUFA2, SURF1, NDUFA10, FOXRED1, NDUFAF6, NDUFV1, COX10, NDUFAF5, NDUFS3
cellular macromolecular complex assembly (GO:0034622)	3.18	20	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA12, NDUFS4, NDUFA9, MT-CO3, BCS1L, NDUFS7, NDUFAF2, NDUFA2, SURF1, NDUFA10, FOXRED1, NDUFAF6, NDUFV1, COX10, NDUFAF5, NDUFS3
cellular protein complex assembly (GO:0043623)	3.9	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, MT-ND3, NDUFAF6, BCS1L, SURF1, NDUFA10, NDUFA12, NDUFS3, NDUFAF2, NDUFV1, NDUFAF5, COX10
cellular component organization or biogenesis (GO:0071840)	1.22	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFA10, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF6, BCS1L, MT-ND3, COX10, NDUFA12, SURF1, NDUFAF2, NDUFV1, NDUFAF5, NDUFS3
oxidation-reduction process (GO:0055114)	2.91	19	NDUFS8, ECHS1, MT-CO3, MT-ND3, NDUFA9, MT-ND5, NDUFA10, FOXRED1, NDUFS7, NDUFA2, SURF1, NDUFS3, NDUFA12, NDUFAF2, COX15, NDUFV1, NDUFS4, COX10, SDHA
generation of precursor metabolites and energy (GO:0006091)	4.07	17	NDUFS8, COX15, MT-CO3, MT-ND5, NDUFA9, NDUFA10, SURF1, NDUFS7, NDUFA2, MT-ND3, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, COX10, SDHA
mitochondrial respiratory chain complex assembly (GO:0033108)	5.31	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF6, BCS1L, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFAF5, NDUFA10
mitochondrial respiratory chain complex I assembly (GO:0032981)	5.6	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF2, BCS1L, NDUFA10, NDUFA12, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3
mitochondrial respiratory chain complex I biogenesis (GO:0097031)	5.6	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF2, BCS1L, NDUFA10, NDUFA12, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3
protein complex biogenesis (GO:0070271)	5.37	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF6, BCS1L, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFAF5, NDUFA10
NADH dehydrogenase complex assembly (GO:0010257)	5.6	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF6, BCS1L, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFAF5, NDUFA10
electron transport chain (GO:0022900)	5.09	16	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, MT-CO3, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFAF2, NDUFV1, COX10, NDUFS4, NDUFS3, SDHA
respiratory electron transport chain (GO:0022904)	5.11	16	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, MT-CO3, NDUFA10, NDUFS7, NDUFA2, SDHA, NDUFA12, NDUFAF2, NDUFV1, COX10, NDUFS4, NDUFS3
cellular component biogenesis (GO:0044085)	4.46	16	FOXRED1, MT-ND3, MT-ND5, NDUFS4, NDUFA9, NDUFS8, NDUFA2, NDUFS7, NDUFAF6, BCS1L, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFAF5, NDUFA10
organic substance metabolic process (GO:0071704)	0.63	11	MTFMT, ECHS1, NDUFA9, NARS2, MT-ATP6, POLG, IARS2, SURF1, SDHA, COX15, COX10
mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	5.84	11	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
biosynthetic process (GO:0009058)	1.32	10	MTFMT, COX15, NDUFA9, NARS2, SURF1, POLG, IARS2, MT-ATP6, NDUFAF6, COX10
cellular biosynthetic process (GO:0044249)	1.37	9	MTFMT, COX15, NDUFA9, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
organic substance biosynthetic process (GO:1901576)	1.34	9	MTFMT, COX15, NDUFA9, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
primary metabolic process (GO:0044238)	0.69	8	MTFMT, ECHS1, NARS2, SURF1, POLG, IARS2, SDHA, MT-ATP6
cellular nitrogen compound biosynthetic process (GO:0044271)	1.59	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
response to stimulus (GO:0050896)	1.22	8	NDUFS8, MT-ND3, MT-ND5, POLG, MT-ATP6, NDUFA12, NDUFS4, NDUFA10
cellular aromatic compound metabolic process (GO:0006725)	1.3	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
cellular nitrogen compound metabolic process (GO:0034641)	1.22	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
nitrogen compound metabolic process (GO:0006807)	1.13	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
organic cyclic compound metabolic process (GO:1901360)	1.26	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
heterocycle metabolic process (GO:0046483)	1.31	8	MTFMT, COX15, NARS2, SURF1, POLG, IARS2, MT-ATP6, COX10
cellular respiration (GO:0045333)	5.9	7	COX15, MT-CO3, SURF1, NDUFAF2, NDUFS4, NDUFV1, COX10
organonitrogen compound metabolic process (GO:1901564)	2.32	7	MTFMT, COX15, NARS2, SURF1, IARS2, MT-ATP6, COX10
small molecule metabolic process (GO:0044281)	2.38	7	ECHS1, NDUFA9, NARS2, SURF1, SDHA, IARS2, MT-ATP6
organonitrogen compound biosynthetic process (GO:1901566)	2.85	7	MTFMT, COX15, NARS2, SURF1, IARS2, MT-ATP6, COX10
energy derivation by oxidation of organic compounds (GO:0015980)	4.93	7	COX15, MT-CO3, SURF1, NDUFAF2, NDUFS4, NDUFV1, COX10
nucleobase-containing compound metabolic process (GO:0006139)	1.35	6	MTFMT, NARS2, SURF1, POLG, IARS2, MT-ATP6
cation transport (GO:0006812)	3.11	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
ion transport (GO:0006811)	2.66	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
transport (GO:0006810)	1.51	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
localization (GO:0051179)	1.4	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
response to stress (GO:0006950)	1.8	6	NDUFS8, MT-ND3, MT-ND5, POLG, MT-ATP6, NDUFA12
establishment of localization (GO:0051234)	1.48	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
monovalent inorganic cation transport (GO:0015672)	3.74	6	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
developmental process (GO:0032502)	1.36	5	NDUFS3, MT-ATP6, NDUFS4, SDHA, POLG
single-organism biosynthetic process (GO:0044711)	2.8	5	SURF1, COX15, MT-ATP6, COX10, NDUFA9
proton transport (GO:0015992)	4.73	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
hydrogen ion transmembrane transport (GO:1902600)	4.97	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
inorganic ion transmembrane transport (GO:0098660)	3.38	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
cytochrome complex assembly (GO:0017004)	6.4	5	BCS1L, SURF1, COX15, MT-CO3, COX10
respiratory chain complex IV assembly (GO:0008535)	6.73	5	BCS1L, SURF1, COX15, MT-CO3, COX10
ion transmembrane transport (GO:0034220)	3.08	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
single-organism transport (GO:0044765)	2.18	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
hydrogen transport (GO:0006818)	4.72	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
biological regulation (GO:0065007)	0.39	5	NDUFS4, NDUFAF2, IARS2, NDUFS3, POLG
inorganic cation transmembrane transport (GO:0098662)	3.55	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
aromatic compound biosynthetic process (GO:0019438)	1.7	5	COX15, MT-ATP6, SURF1, COX10, POLG
response to chemical (GO:0042221)	1.98	5	NDUFS4, MT-ND5, NDUFA10, MT-ND3, POLG
cation transmembrane transport (GO:0098655)	3.43	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
organic cyclic compound biosynthetic process (GO:1901362)	1.66	5	SURF1, POLG, COX15, MT-ATP6, COX10
transmembrane transport (GO:0055085)	2.72	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
single-organism localization (GO:1902578)	2.09	5	COX15, SURF1, MT-CO3, MT-ATP6, COX10
heterocycle biosynthetic process (GO:0018130)	1.7	5	SURF1, POLG, COX15, MT-ATP6, COX10
response to abiotic stimulus (GO:0009628)	2.8	4	MT-ATP6, MT-ND5, MT-ND3, POLG
nucleic acid metabolic process (GO:0090304)	1.46	4	MTFMT, IARS2, NARS2, POLG
organic acid metabolic process (GO:0006082)	3.01	4	ECHS1, IARS2, NARS2, SDHA
cellular macromolecule metabolic process (GO:0044260)	0.93	4	MTFMT, IARS2, NARS2, POLG
macromolecule biosynthetic process (GO:0009059)	1.61	4	MTFMT, IARS2, NARS2, POLG
regulation of cellular process (GO:0050794)	0.5	4	NDUFAF2, IARS2, NDUFS4, NDUFS3
single-organism developmental process (GO:0044767)	1.49	4	NDUFS4, MT-ATP6, NDUFS3, POLG
regulation of biological process (GO:0050789)	0.45	4	NDUFAF2, IARS2, NDUFS4, NDUFS3
aerobic respiration (GO:0009060)	6.4	4	SURF1, MT-CO3, NDUFV1, COX10
carboxylic acid metabolic process (GO:0019752)	3.12	4	NARS2, IARS2, ECHS1, SDHA
cellular macromolecule biosynthetic process (GO:0034645)	1.66	4	MTFMT, IARS2, NARS2, POLG
oxoacid metabolic process (GO:0043436)	3.12	4	ECHS1, IARS2, NARS2, SDHA
macromolecule metabolic process (GO:0043170)	0.83	4	MTFMT, IARS2, NARS2, POLG
response to oxidative stress (GO:0006979)	3.9	4	NDUFS8, MT-ND5, MT-ND3, NDUFA12
response to organic substance (GO:0010033)	2.2	4	NDUFS4, MT-ND5, MT-ND3, POLG
RNA metabolic process (GO:0016070)	1.59	3	MTFMT, IARS2, NARS2
response to oxygen-containing compound (GO:1901700)	2.57	3	NDUFS4, MT-ND5, POLG
cofactor metabolic process (GO:0051186)	3.91	3	NDUFA9, COX15, COX10
cellular amide metabolic process (GO:0043603)	3.23	3	MTFMT, IARS2, NARS2
cellular protein metabolic process (GO:0044267)	1.63	3	MTFMT, IARS2, NARS2
protein metabolic process (GO:0019538)	1.45	3	MTFMT, IARS2, NARS2
mitochondrial electron transport, cytochrome c to oxygen (GO:0006123)	6.73	3	COX15, MT-CO3, COX10
anatomical structure development (GO:0048856)	1.58	3	NDUFS4, NDUFS3, SDHA
peptide biosynthetic process (GO:0043043)	3.73	3	MTFMT, IARS2, NARS2
cofactor biosynthetic process (GO:0051188)	4.62	3	NDUFA9, COX15, COX10
reactive oxygen species metabolic process (GO:0072593)	5.14	3	NDUFAF2, NDUFS4, NDUFS3
response to endogenous stimulus (GO:0009719)	2.79	3	NDUFS4, MT-ND5, MT-ND3
tRNA metabolic process (GO:0006399)	4.52	3	MTFMT, IARS2, NARS2
amide biosynthetic process (GO:0043604)	3.6	3	MTFMT, IARS2, NARS2
nucleobase-containing compound biosynthetic process (GO:0034654)	1.72	3	SURF1, MT-ATP6, POLG
ncRNA metabolic process (GO:0034660)	3.44	3	MTFMT, IARS2, NARS2
peptide metabolic process (GO:0006518)	3.44	3	MTFMT, IARS2, NARS2
regulation of biological quality (GO:0065008)	1.68	3	NDUFAF2, IARS2, POLG
translation (GO:0006412)	3.79	3	MTFMT, IARS2, NARS2
response to oxygen levels (GO:0070482)	4.02	3	MT-ATP6, MT-ND5, POLG
regulation of primary metabolic process (GO:0080090)	1.08	2	IARS2, NDUFS4
regulation of metabolic process (GO:0019222)	1.02	2	IARS2, NDUFS4
negative regulation of response to stimulus (GO:0048585)	2.52	2	NDUFAF2, NDUFS3
regulation of response to stimulus (GO:0048583)	1.54	2	NDUFAF2, NDUFS3
porphyrin-containing compound metabolic process (GO:0006778)	6.09	2	COX15, COX10
porphyrin-containing compound biosynthetic process (GO:0006779)	6.47	2	COX15, COX10
purine ribonucleoside monophosphate metabolic process (GO:0009167)	4.7	2	SURF1, MT-ATP6
nucleotide biosynthetic process (GO:0009165)	4.49	2	SURF1, MT-ATP6
nucleoside biosynthetic process (GO:0009163)	4.97	2	SURF1, MT-ATP6
ribonucleoside monophosphate metabolic process (GO:0009161)	4.62	2	SURF1, MT-ATP6
purine nucleoside biosynthetic process (GO:0042451)	5.25	2	SURF1, MT-ATP6
mitochondrion organization (GO:0007005)	3.69	2	BCS1L, COX10
cellular response to stimulus (GO:0051716)	1.97	2	MT-ND3, POLG
pigment metabolic process (GO:0042440)	5.59	2	COX15, COX10
heme biosynthetic process (GO:0006783)	6.68	2	COX15, COX10
heme a biosynthetic process (GO:0006784)	9.04	2	COX15, COX10
ribonucleoside triphosphate metabolic process (GO:0009199)	4.77	2	SURF1, MT-ATP6
negative regulation of biological process (GO:0048519)	1.33	2	NDUFAF2, NDUFS3
purine ribonucleoside triphosphate biosynthetic process (GO:0009206)	5.82	2	SURF1, MT-ATP6
purine ribonucleoside triphosphate metabolic process (GO:0009205)	4.81	2	SURF1, MT-ATP6
ribonucleoside triphosphate biosynthetic process (GO:0009201)	5.7	2	SURF1, MT-ATP6
phosphorus metabolic process (GO:0006793)	2.15	2	SURF1, MT-ATP6
regulation of macromolecule metabolic process (GO:0060255)	1.08	2	IARS2, NDUFS4
ATP metabolic process (GO:0046034)	4.98	2	SURF1, MT-ATP6
purine ribonucleoside biosynthetic process (GO:0046129)	5.25	2	SURF1, MT-ATP6
purine ribonucleoside metabolic process (GO:0046128)	4.33	2	SURF1, MT-ATP6
ribonucleoside biosynthetic process (GO:0042455)	5.06	2	SURF1, MT-ATP6
single-multicellular organism process (GO:0044707)	1.78	2	COX15, NDUFA12
response to organonitrogen compound (GO:0010243)	3.2	2	NDUFS4, MT-ND5
purine nucleotide metabolic process (GO:0006163)	4.09	2	SURF1, MT-ATP6
amino acid activation (GO:0043038)	5.76	2	IARS2, NARS2
tRNA aminoacylation (GO:0043039)	5.76	2	IARS2, NARS2
purine nucleotide biosynthetic process (GO:0006164)	4.87	2	SURF1, MT-ATP6
organophosphate metabolic process (GO:0019637)	3.04	2	SURF1, MT-ATP6
nucleoside triphosphate metabolic process (GO:0009141)	4.61	2	SURF1, MT-ATP6
nucleoside triphosphate biosynthetic process (GO:0009142)	5.51	2	SURF1, MT-ATP6
purine nucleoside triphosphate metabolic process (GO:0009144)	4.76	2	SURF1, MT-ATP6
purine nucleoside triphosphate biosynthetic process (GO:0009145)	5.8	2	SURF1, MT-ATP6
purine nucleoside monophosphate biosynthetic process (GO:0009127)	5.54	2	SURF1, MT-ATP6
tetrapyrrole biosynthetic process (GO:0033014)	6.36	2	COX15, COX10
tetrapyrrole metabolic process (GO:0033013)	5.65	2	COX15, COX10
purine ribonucleoside monophosphate biosynthetic process (GO:0009168)	5.54	2	SURF1, MT-ATP6
ribonucleoside monophosphate biosynthetic process (GO:0009156)	5.36	2	SURF1, MT-ATP6
purine ribonucleotide biosynthetic process (GO:0009152)	4.92	2	SURF1, MT-ATP6
purine ribonucleotide metabolic process (GO:0009150)	4.16	2	SURF1, MT-ATP6
ribonucleotide biosynthetic process (GO:0009260)	4.82	2	SURF1, MT-ATP6
organophosphate biosynthetic process (GO:0090407)	3.67	2	SURF1, MT-ATP6
pigment biosynthetic process (GO:0046148)	5.86	2	COX15, COX10
response to nitrogen compound (GO:1901698)	3.12	2	NDUFS4, MT-ND5
ribose phosphate biosynthetic process (GO:0046390)	4.79	2	SURF1, MT-ATP6
nucleoside phosphate biosynthetic process (GO:1901293)	4.47	2	SURF1, MT-ATP6
nucleoside phosphate metabolic process (GO:0006753)	3.71	2	SURF1, MT-ATP6
ATP biosynthetic process (GO:0006754)	6.04	2	SURF1, MT-ATP6
response to radiation (GO:0009314)	3.69	2	MT-ND3, POLG
negative regulation of signaling (GO:0023057)	2.65	2	NDUFAF2, NDUFS3
response to light stimulus (GO:0009416)	4.08	2	MT-ND3, POLG
negative regulation of cell communication (GO:0010648)	2.66	2	NDUFAF2, NDUFS3
cellular response to chemical stimulus (GO:0070887)	2.57	2	MT-ND3, POLG
regulation of signaling (GO:0023051)	1.72	2	NDUFAF2, NDUFS3
nucleoside monophosphate metabolic process (GO:0009123)	4.54	2	SURF1, MT-ATP6
regulation of cell communication (GO:0010646)	1.73	2	NDUFAF2, NDUFS3
purine nucleoside monophosphate metabolic process (GO:0009126)	4.69	2	SURF1, MT-ATP6
ribonucleotide metabolic process (GO:0009259)	4.11	2	SURF1, MT-ATP6
response to organic cyclic compound (GO:0014070)	3.07	2	NDUFS4, MT-ND3
purine nucleoside metabolic process (GO:0042278)	4.32	2	SURF1, MT-ATP6
regulation of protein metabolic process (GO:0051246)	1.93	2	IARS2, NDUFS4
heme metabolic process (GO:0042168)	6.33	2	COX15, COX10
heme a metabolic process (GO:0046160)	9.04	2	COX15, COX10
nucleobase-containing small molecule metabolic process (GO:0055086)	3.59	2	SURF1, MT-ATP6
regulation of cellular protein metabolic process (GO:0032268)	1.99	2	IARS2, NDUFS4
aging (GO:0007568)	4.16	2	MT-ATP6, POLG
carbohydrate derivative biosynthetic process (GO:1901137)	3.73	2	SURF1, MT-ATP6
carbohydrate derivative metabolic process (GO:1901135)	3.07	2	SURF1, MT-ATP6
nucleoside monophosphate biosynthetic process (GO:0009124)	5.26	2	SURF1, MT-ATP6
response to increased oxygen levels (GO:0036296)	6.4	2	MT-ATP6, POLG
regulation of cellular metabolic process (GO:0031323)	1.07	2	IARS2, NDUFS4
multicellular organismal process (GO:0032501)	1.45	2	COX15, NDUFA12
purine-containing compound metabolic process (GO:0072521)	4.0	2	SURF1, MT-ATP6
purine-containing compound biosynthetic process (GO:0072522)	4.79	2	SURF1, MT-ATP6
response to hyperoxia (GO:0055093)	6.4	2	MT-ATP6, POLG
cellular amino acid metabolic process (GO:0006520)	4.22	2	IARS2, NARS2
cellular response to organic substance (GO:0071310)	2.78	2	MT-ND3, POLG
respiratory gaseous exchange (GO:0007585)	5.86	2	COX15, NDUFA12
nucleotide metabolic process (GO:0009117)	3.73	2	SURF1, MT-ATP6
nucleoside metabolic process (GO:0009116)	4.12	2	SURF1, MT-ATP6
ribonucleoside metabolic process (GO:0009119)	4.21	2	SURF1, MT-ATP6
organelle organization (GO:0006996)	2.02	2	BCS1L, COX10
ribose phosphate metabolic process (GO:0019693)	4.06	2	SURF1, MT-ATP6
glycosyl compound metabolic process (GO:1901657)	4.04	2	SURF1, MT-ATP6
phosphate-containing compound metabolic process (GO:0006796)	2.16	2	SURF1, MT-ATP6
tRNA aminoacylation for protein translation (GO:0006418)	5.82	2	IARS2, NARS2
negative regulation of cellular process (GO:0048523)	1.41	2	NDUFAF2, NDUFS3
glycosyl compound biosynthetic process (GO:1901659)	4.95	2	SURF1, MT-ATP6

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
cellular component assembly (GO:0022607)	-	2.14	0.014	NDUFS8, COX15, MT-CO3, SURF1, NDUFS7, BCS1L, NDUFAF6, NDUFAF5, NDUFS4, COX10
protein complex biogenesis (GO:0070271)	-	5.37	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5
hydrogen ion transmembrane transport (GO:1902600)	-	4.97	0.0	COX15, SURF1, MT-CO3, MT-ATP6, COX10
cytochrome complex assembly (GO:0017004)	-	6.4	0.0	BCS1L, SURF1, COX15, MT-CO3, COX10
aerobic respiration (GO:0009060)	-	6.4	0.001	SURF1, COX15, MT-CO3, COX10
small molecule metabolic process (GO:0044281)	-	2.38	0.0	NDUFS8, ECHS1, MT-ND3, MT-CO3, NDUFA9, MT-ND5, NARS2, IARS2, SDHA, NDUFA2, NDUFS7, SURF1, NDUFA10, NDUFA12, MT-ATP6, COX15, NDUFV1, COX10, NDUFS4, NDUFS3
cellular macromolecular complex assembly (GO:0034622)	-	3.18	0.001	NDUFS8, COX15, MT-CO3, NDUFA2, NDUFS7, SURF1, NDUFAF6, NDUFAF5, BCS1L, NDUFS4, COX10
generation of precursor metabolites and energy (GO:0006091)	-	4.07	0.0	NDUFS8, COX15, MT-CO3, MT-ND5, NDUFA9, NDUFA10, MT-ATP6, NDUFS7, MT-ND3, NDUFA2, SURF1, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, COX10, SDHA
mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	-	5.84	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFV1, NDUFS4, NDUFS3
mitochondrion organization (GO:0007005)	-	3.69	0.002	COX15, NDUFA10, POLG, BCS1L, COX10, NDUFV1, NDUFS3
single-organism metabolic process (GO:0044710)	-	1.63	0.0	NDUFS8, NDUFA10, FOXRED1, SDHA, COX15, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
proton transport (GO:0015992)	-	4.73	0.001	COX15, SURF1, MT-CO3, MT-ATP6, COX10
protein complex subunit organization (GO:0071822)	-	2.6	0.001	NDUFS8, COX15, MT-CO3, SURF1, NDUFS7, BCS1L, NDUFAF6, NDUFAF5, NDUFS4, COX10
mitochondrial respiratory chain complex I assembly (GO:0032981)	-	5.6	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5
NADH dehydrogenase complex assembly (GO:0010257)	-	5.6	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5
heme a biosynthetic process (GO:0006784)	-	9.04	0.001	COX15, COX10
macromolecular complex assembly (GO:0065003)	-	2.55	0.001	NDUFS8, ECHS1, MT-CO3, NDUFS4, NDUFA10, NDUFA2, NDUFS7, BCS1L, SURF1, COX10, MT-ATP6, NDUFAF6, COX15, NDUFV1, NDUFAF5, NDUFS3
macromolecular complex subunit organization (GO:0043933)	-	2.14	0.005	NDUFS8, COX15, MT-CO3, SURF1, NDUFS7, BCS1L, NDUFAF6, NDUFAF5, NDUFS4, COX10
electron transport chain (GO:0022900)	-	5.09	0.0	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, MT-CO3, NDUFA10, SDHA, NDUFA2, NDUFS7, NDUFS3, NDUFA12, MT-ATP6, NDUFAF2, NDUFV1, NDUFS4, COX10
respiratory electron transport chain (GO:0022904)	-	5.11	0.0	NDUFS8, COX15, MT-CO3, MT-ND5, NDUFA9, NDUFA10, MT-ATP6, NDUFS7, NDUFA2, MT-ND3, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, NDUFS4, COX10, SDHA
monovalent inorganic cation transport (GO:0015672)	-	3.74	0.008	COX15, MT-CO3, NDUFA9, MT-ATP6, SURF1, COX10
mitochondrial respiratory chain complex assembly (GO:0033108)	-	5.31	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5
hydrogen transport (GO:0006818)	-	4.72	0.001	COX15, SURF1, MT-CO3, MT-ATP6, COX10
protein complex assembly (GO:0006461)	-	2.78	0.0	NDUFS8, ECHS1, MT-CO3, NDUFS4, NDUFA10, NDUFA2, NDUFS7, BCS1L, SURF1, NDUFS3, MT-ATP6, NDUFAF6, COX15, NDUFV1, NDUFAF5, COX10
heme a metabolic process (GO:0046160)	-	9.04	0.001	COX15, COX10
cellular respiration (GO:0045333)	-	5.9	0.0	COX15, MT-CO3, NDUFA9, SURF1, NDUFS4, COX10
metabolic process (GO:0008152)	-	0.58	0.005	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, SURF1
cellular protein complex assembly (GO:0043623)	-	3.9	0.0	NDUFS8, COX15, MT-CO3, BCS1L, NDUFS7, NDUFA2, SURF1, NDUFAF6, NDUFAF5, NDUFS4, COX10
oxidation-reduction process (GO:0055114)	-	2.91	0.0	NDUFS8, ECHS1, MT-CO3, MT-ND3, NDUFA12, NDUFA9, MT-ND5, NDUFA10, NDUFA2, SDHA, BCS1L, NDUFS7, SURF1, NDUFS3, FOXRED1, MT-ATP6, NDUFAF2, COX15, NDUFV1, NDUFS4, COX10
energy derivation by oxidation of organic compounds (GO:0015980)	-	4.93	0.0	COX15, MT-CO3, NDUFA9, NDUFS7, SURF1, COX10, NDUFS4, NDUFS3
mitochondrial respiratory chain complex I biogenesis (GO:0097031)	-	5.6	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5
mitochondrial electron transport, cytochrome c to oxygen (GO:0006123)	-	6.73	0.002	COX15, COX10
cellular metabolic process (GO:0044237)	-	0.69	0.036	NDUFS8, POLG, COX15, MTFMT, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-ND3, IARS2, SDHA, NDUFS4, COX10, NDUFA10, MT-ND5, NDUFA9, SURF1
respiratory chain complex IV assembly (GO:0008535)	-	6.73	0.0	BCS1L, SURF1, COX15, MT-CO3, COX10
cellular component biogenesis (GO:0044085)	-	4.46	0.0	NDUFS8, NDUFS7, BCS1L, NDUFAF6, NDUFS4, NDUFAF5

GO - cellular component annotation: shared terms / NET-GE enrichment

Shared terms

GO	IC	Number of genes with the same GO	Genes
intracellular membrane-bounded organelle (GO:0043231)	0.6	27	NDUFS8, FOXRED1, POLG, NDUFAF6, COX15, NDUFS3, MTFMT, MT-CO3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, NDUFV1, COX10, MT-ND5, NDUFA9, IARS2, NDUFA2
cell part (GO:0044464)	0.11	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, NDUFS3, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, NDUFV1, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
cytoplasmic part (GO:0044444)	0.82	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
mitochondrion (GO:0005739)	2.42	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
intracellular organelle (GO:0043229)	0.51	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFV1, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
intracellular part (GO:0044424)	0.28	27	NDUFS8, FOXRED1, POLG, NDUFAF6, COX15, NDUFS3, MTFMT, MT-CO3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, NDUFV1, COX10, MT-ND5, NDUFA9, IARS2, NDUFA2
membrane-bounded organelle (GO:0043227)	0.47	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
organelle (GO:0043226)	0.4	27	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
intracellular organelle part (GO:0044446)	0.81	26	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MT-ND3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, BCS1L, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, IARS2, NDUFA2
mitochondrial part (GO:0044429)	2.92	26	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MT-ND3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, BCS1L, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, IARS2, NDUFA2
organelle part (GO:0044422)	0.79	26	FOXRED1, NDUFA10, NDUFS8, POLG, NDUFAF6, COX15, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, NDUFV1, NDUFS3, MT-ND5, NDUFA9, BCS1L, SURF1
membrane (GO:0016020)	0.68	23	FOXRED1, NDUFA10, NDUFS8, SDHA, NDUFAF6, MT-ND3, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF2, NDUFV1, COX15, MT-CO3, IARS2, NDUFS4, NDUFAF5, NDUFS3, MT-ND5, NDUFA9, BCS1L, SURF1
membrane part (GO:0044425)	0.95	21	NDUFS8, NDUFS4, COX15, NDUFA12, MT-CO3, IARS2, NDUFA9, MT-ND5, NDUFA2, SDHA, MT-ND3, BCS1L, NDUFS7, SURF1, NDUFA10, FOXRED1, MT-ATP6, NDUFV1, COX10, NDUFAF5, NDUFS3
organelle membrane (GO:0031090)	1.97	21	FOXRED1, COX15, MT-ND3, MT-ND5, NDUFS4, NDUFS3, NDUFA9, MT-CO3, NDUFA2, SDHA, NDUFAF2, BCS1L, NDUFS7, SURF1, NDUFA10, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, NDUFAF5, COX10
mitochondrial membrane (GO:0031966)	3.31	21	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA9, NDUFA10, NDUFA2, NDUFS7, MT-ND3, NDUFAF2, BCS1L, SURF1, NDUFS3, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, NDUFAF5, COX10, SDHA
mitochondrial inner membrane (GO:0005743)	3.65	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA10, NDUFA2, NDUFS7, MT-ND3, NDUFAF2, BCS1L, SURF1, SDHA, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, COX10, NDUFAF5, NDUFS3
organelle inner membrane (GO:0019866)	3.56	20	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS4, NDUFA10, NDUFA2, NDUFS7, MT-ND3, NDUFAF2, BCS1L, SURF1, COX10, NDUFA12, MT-ATP6, NDUFAF6, NDUFV1, NDUFAF5, NDUFS3, SDHA
protein complex (GO:0043234)	1.51	19	FOXRED1, COX15, MT-CO3, MT-ND5, NDUFS8, NDUFA9, NDUFA10, NDUFA2, POLG, BCS1L, NDUFS7, MT-ND3, SDHA, NDUFA12, MT-ATP6, NDUFV1, COX10, NDUFS4, NDUFS3
macromolecular complex (GO:0032991)	1.35	19	FOXRED1, COX15, MT-ND3, MT-ND5, NDUFS8, NDUFA9, MT-CO3, NDUFA2, POLG, BCS1L, NDUFS7, NDUFA10, NDUFA12, MT-ATP6, NDUFS3, NDUFV1, NDUFS4, COX10, SDHA
mitochondrial membrane part (GO:0044455)	4.54	18	NDUFS8, COX15, NDUFA12, MT-ND3, NDUFS4, NDUFA9, MT-ND5, NDUFA2, NDUFS7, BCS1L, SURF1, NDUFA10, FOXRED1, MT-ATP6, NDUFV1, NDUFAF5, NDUFS3, SDHA
membrane protein complex (GO:0098796)	2.84	16	FOXRED1, MT-ND3, MT-ND5, NDUFA10, NDUFS8, NDUFA9, MT-CO3, NDUFA2, SDHA, BCS1L, NDUFS7, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, NDUFS3
mitochondrial protein complex (GO:0098798)	4.78	16	NDUFS8, MT-ND3, MT-ND5, NDUFA12, NDUFA9, NDUFA2, POLG, BCS1L, NDUFS7, NDUFA10, FOXRED1, MT-ATP6, NDUFV1, NDUFS4, NDUFS3, SDHA
respiratory chain complex (GO:0098803)	5.47	15	FOXRED1, MT-CO3, MT-ND5, NDUFS8, NDUFA9, NDUFA10, NDUFA2, NDUFS7, BCS1L, MT-ND3, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
catalytic complex (GO:1902494)	2.9	15	FOXRED1, MT-ND3, MT-ND5, NDUFS8, NDUFA9, NDUFA10, NDUFA2, POLG, BCS1L, NDUFS7, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
inner mitochondrial membrane protein complex (GO:0098800)	5.01	15	FOXRED1, MT-ND3, MT-ND5, NDUFA10, NDUFA9, NDUFS8, NDUFA2, SDHA, BCS1L, NDUFS7, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, NDUFS3
respiratory chain (GO:0070469)	5.51	14	NDUFS8, COX15, MT-ND3, MT-ND5, NDUFA9, FOXRED1, NDUFS7, NDUFA2, SURF1, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
oxidoreductase complex (GO:1990204)	5.19	14	NDUFS8, MT-ND3, MT-ND5, NDUFA12, NDUFA9, NDUFA2, NDUFS7, BCS1L, NDUFA10, FOXRED1, NDUFV1, NDUFS4, NDUFS3, SDHA
NADH dehydrogenase complex (GO:0030964)	5.91	12	FOXRED1, MT-ND3, MT-ND5, NDUFA9, NDUFS8, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
respiratory chain complex I (GO:0045271)	5.91	12	FOXRED1, MT-ND3, MT-ND5, NDUFA9, NDUFS8, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
mitochondrial respiratory chain complex I (GO:0005747)	5.91	12	FOXRED1, MT-ND3, MT-ND5, NDUFA9, NDUFS8, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
integral component of membrane (GO:0016021)	1.14	10	FOXRED1, COX15, MT-ND3, MT-ND5, MT-CO3, BCS1L, IARS2, SURF1, MT-ATP6, COX10
intrinsic component of membrane (GO:0031224)	1.13	10	FOXRED1, COX15, MT-ND3, MT-ND5, MT-CO3, BCS1L, IARS2, SURF1, MT-ATP6, COX10
mitochondrial matrix (GO:0005759)	4.03	8	NDUFS8, ECHS1, NDUFA9, NARS2, NDUFS7, IARS2, NDUFA10, NDUFS3
intracellular organelle lumen (GO:0070013)	3.05	8	NDUFS8, ECHS1, NDUFA9, NARS2, NDUFS7, IARS2, NDUFA10, NDUFS3
membrane-enclosed lumen (GO:0031974)	3.05	8	NDUFS8, ECHS1, NDUFA9, NARS2, NDUFS7, IARS2, NDUFA10, NDUFS3
organelle lumen (GO:0043233)	3.05	8	NDUFS8, ECHS1, NDUFA9, NARS2, NDUFS7, IARS2, NDUFA10, NDUFS3
cytochrome complex (GO:0070069)	6.51	4	BCS1L, COX15, MT-CO3, COX10
cytoplasm (GO:0005737)	1.01	3	NDUFAF6, IARS2, NARS2
extracellular organelle (GO:0043230)	1.89	3	MT-ATP6, ECHS1, POLG
vesicle (GO:0031982)	1.64	3	MT-ATP6, ECHS1, POLG
myelin sheath (GO:0043209)	4.76	3	NDUFA10, NDUFS3, SDHA
nucleus (GO:0005634)	1.07	3	NDUFAF6, NDUFA9, NDUFS3
membrane-bounded vesicle (GO:0031988)	1.71	3	MT-ATP6, ECHS1, POLG
neuron part (GO:0097458)	2.64	3	NDUFS7, MT-ND5, POLG
extracellular vesicle (GO:1903561)	1.89	3	MT-ATP6, ECHS1, POLG
extracellular region part (GO:0044421)	1.57	3	MT-ATP6, ECHS1, POLG
extracellular exosome (GO:0070062)	1.89	3	MT-ATP6, ECHS1, POLG
synapse part (GO:0044456)	3.42	2	NDUFS7, POLG
cell projection (GO:0042995)	2.47	2	NDUFS7, MT-ND5
mitochondrial respiratory chain (GO:0005746)	7.16	2	SURF1, COX15
neuron projection (GO:0043005)	3.12	2	NDUFS7, MT-ND5

NET-GE enrichment

Term	New enriched term	IC	P value	Genes
oxidoreductase complex (GO:1990204)	-	5.19	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFA2, NDUFS7, BCS1L, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3, SDHA
cytochrome complex (GO:0070069)	-	6.51	0.024	BCS1L, MT-CO3
organelle membrane (GO:0031090)	-	1.97	0.0	NDUFS8, NDUFA10, POLG, NDUFAF6, COX15, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFV1, ECHS1, MT-CO3, BCS1L, SDHA, NDUFS4, NDUFS3, MT-ND5, NDUFA9, SURF1
mitochondrion (GO:0005739)	-	2.42	0.0	MTFMT, FOXRED1, ECHS1, NDUFS8, NDUFS3, NDUFA9, NARS2, BCS1L, POLG, NDUFAF6, IARS2, NDUFS7, NDUFA10, NDUFA12, MT-ATP6, NDUFAF2, COX15, NDUFV1, NDUFS4, COX10, SDHA
mitochondrial membrane part (GO:0044455)	-	4.54	0.0	NDUFS8, COX15, MT-ND3, MT-CO3, NDUFS4, NDUFA9, MT-ND5, NDUFA2, NDUFS7, BCS1L, SURF1, NDUFA10, NDUFA12, MT-ATP6, NDUFV1, NDUFAF5, NDUFS3, SDHA
mitochondrial matrix (GO:0005759)	-	4.03	0.002	ECHS1, NDUFA9, NARS2, IARS2, NDUFA10, NDUFS3
mitochondrial respiratory chain complex I (GO:0005747)	-	5.91	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
catalytic complex (GO:1902494)	-	2.9	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFA10, NDUFA2, POLG, BCS1L, NDUFS7, SDHA, NDUFA12, NDUFV1, NDUFS4, NDUFS3
mitochondrial membrane (GO:0031966)	-	3.31	0.0	NDUFS8, ECHS1, MT-ND3, MT-CO3, NDUFA9, MT-ND5, NDUFA10, NDUFA2, POLG, BCS1L, NDUFS7, NDUFS3, NDUFA12, MT-ATP6, NDUFAF6, COX15, NDUFV1, NDUFS4, COX10, SDHA
protein complex (GO:0043234)	-	1.51	0.001	NDUFS8, MT-CO3, MT-ND5, NDUFA9, NDUFA10, NDUFA2, POLG, BCS1L, MT-ND3, NDUFS7, NDUFA12, MT-ATP6, NDUFV1, NDUFS4, NDUFS3, SDHA
respiratory chain complex I (GO:0045271)	-	5.91	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
macromolecular complex (GO:0032991)	-	1.35	0.012	NDUFS8, MT-ND3, MT-ND5, NDUFA9, MT-CO3, NDUFA2, POLG, BCS1L, NDUFS7, SDHA, NDUFA12, MT-ATP6, NDUFS3, NDUFV1, NDUFS4, NDUFA10
NADH dehydrogenase complex (GO:0030964)	-	5.91	0.0	NDUFS8, MT-ND3, MT-ND5, NDUFA9, NDUFS7, NDUFA2, NDUFA10, NDUFA12, NDUFV1, NDUFS4, NDUFS3
organelle inner membrane (GO:0019866)	-	3.56	0.0	NDUFS8, ECHS1, MT-CO3, MT-ND5, NDUFA9, NDUFA10, BCS1L, POLG, NDUFA2, NDUFS7, MT-ND3, NDUFS3, NDUFA12, MT-ATP6, NDUFAF6, COX15, NDUFV1, NDUFS4, COX10, SDHA
intracellular organelle part (GO:0044446)	-	0.81	0.0	NDUFS8, POLG, NDUFAF6, COX15, MT-CO3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, IARS2, NDUFA2
mitochondrial inner membrane (GO:0005743)	-	3.65	0.0	NDUFS8, ECHS1, MT-CO3, MT-ND5, NDUFA9, NDUFA10, NDUFA2, POLG, BCS1L, NDUFS7, MT-ND3, SDHA, NDUFA12, MT-ATP6, NDUFAF6, COX15, NDUFV1, COX10, NDUFS4, NDUFS3
cytoplasmic part (GO:0044444)	-	0.82	0.0	FOXRED1, NDUFS8, POLG, NDUFAF6, COX15, MTFMT, MT-ND3, NARS2, NDUFA2, NDUFS7, MT-ATP6, NDUFS3, NDUFA12, NDUFAF2, NDUFV1, ECHS1, MT-CO3, IARS2, SDHA, NDUFS4, COX10, NDUFAF5, NDUFA10, MT-ND5, NDUFA9, BCS1L, SURF1
mitochondrial respiratory chain (GO:0005746)	-	7.16	0.017	SURF1, COX15
mitochondrial part (GO:0044429)	-	2.92	0.0	NDUFS8, POLG, NDUFAF6, COX15, MT-CO3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, COX10, NDUFV1, NDUFS3, MT-ND5, NDUFA9, IARS2, NDUFA2
intracellular part (GO:0044424)	-	0.28	0.01	NDUFS8, FOXRED1, POLG, NDUFAF6, COX15, NDUFS3, MTFMT, MT-CO3, NARS2, SURF1, NDUFS7, MT-ATP6, NDUFA10, NDUFA12, NDUFAF2, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, NDUFV1, COX10, MT-ND5, NDUFA9, IARS2, NDUFA2
membrane part (GO:0044425)	-	0.95	0.004	NDUFS8, COX15, NDUFA12, MT-CO3, NDUFS4, NDUFA9, MT-ND5, NDUFA2, SDHA, MT-ND3, BCS1L, NDUFS7, SURF1, NDUFA10, FOXRED1, MT-ATP6, NDUFV1, COX10, NDUFAF5, NDUFS3
respiratory chain (GO:0070469)	-	5.51	0.042	SURF1, COX15
organelle part (GO:0044422)	-	0.79	0.0	NDUFS8, NDUFA10, POLG, NDUFAF6, COX15, MT-CO3, NARS2, NDUFA2, NDUFS7, MT-ATP6, COX10, NDUFA12, NDUFAF5, ECHS1, MT-ND3, BCS1L, SDHA, NDUFS4, NDUFV1, NDUFS3, MT-ND5, NDUFA9, IARS2, SURF1